<strong>Objectives:</strong> To identify the main risk factors of vascular cognitive impairment in patients with acute cerebral infarction by Meta-analysis, and provide references for the effective prevent...<strong>Objectives:</strong> To identify the main risk factors of vascular cognitive impairment in patients with acute cerebral infarction by Meta-analysis, and provide references for the effective prevention of the cognitive impairment in stroke patients. <strong>Methods:</strong> To retrieve the observational research literatures that refer to the risk factors of vascular cognitive impairment in patients with ischemic stroke, which are published on China National Knowledge Infrastructure (CNKI), Wanfang and Weipu Chinese databases. The screening and data extraction of these literatures are independently completed by two researchers, who also give the quality evaluation of the literatures according to the evaluation criterion of the Australian JBI Evidence-Based Health Care Center. Then, Meta-analysis is conducted by using Revman5.3 software. <strong>Results:</strong> There are twenty-eight articles selected from 1507 literatures, with a total of 10,711 cases and 50 risk factors included. Among them, there are combined effects of ten factors which have statistical significance, such as infarction area, alcohol consumption, smoking, hyper homocysteinemia, hypertension, diabetes mellitus, age, history of cerebral infarction, hyperlipoidemia and education level. The relational merging OR value and 95% CI between the type-variable factors and cognitive impairment are 3.25 (1.84, 5.76);2.98 (2.58, 3.45);2.79 (1.69, 4.59);2.35 (1.93, 2.85);2.25 (1.86, 2.71);2.14 (2.10, 2.18);1.82 (1.62, 2.03);1.54 (1.24, 1.92);1.45 (1.34, 1.56);0.83 (0.78, 0.89). <strong>Conclusion: </strong>Infarction area, alcohol consumption, smoking, hyper homocysteinemia, hypertension, diabetesmellitus, age, history of cerebral infarction, hyperlipoidemia and low education level are the main risk factors for vascular cognitive impairment in patients with acute cerebral infarction. Clinical nursing staff should include it into the routine assessment of patients with acute cerebral infarction and actively prevent and intervene.展开更多
Cerebral ischemia is the pathophysiological condition in which the oxygenated cerebral blood flow is less than what is needed to meet cerebral metabolic demand.It is one of the most debilitating complications in the p...Cerebral ischemia is the pathophysiological condition in which the oxygenated cerebral blood flow is less than what is needed to meet cerebral metabolic demand.It is one of the most debilitating complications in the perioperative period and has serious clinical sequelae.The monitoring and prevention of intraoperative cerebral ischemia are crucial because an anesthetized patient in the operating room cannot be neurologically assessed.In this paper,we provide an overview of the definition,etiology,risk factors,and prevention of cerebral ischemia during surgery.展开更多
目的:分析高血压脑出血术后肺部感染危险因素。方法:检索中国知网、万方、维普、PubMed、EMBASE、Web of Science和Cochrane Library有关危险因素相关研究。检索时限从建库至2024年4月,筛选符合要求的文献,并进行质量评价和提取相比值比...目的:分析高血压脑出血术后肺部感染危险因素。方法:检索中国知网、万方、维普、PubMed、EMBASE、Web of Science和Cochrane Library有关危险因素相关研究。检索时限从建库至2024年4月,筛选符合要求的文献,并进行质量评价和提取相比值比(OR)及95%CI,采用RevMan5.4软件进行Meta分析。结果:有13篇文献符合要求,共计689例高血压脑出血患者。通过Meta分析后认为危险因素包括吸烟史、糖尿病、低蛋白血症、机械通气时间、侵入性操作、气管切开、GCS<8、鼻饲;描述性分析结果显示:年龄、GCS与术后发生肺部感染有关。结论:高血压脑出血肺部感染危险因素较多,尽早识别危险因素,采取相关防治措施,有利于降低肺部感染发病率。展开更多
文摘<strong>Objectives:</strong> To identify the main risk factors of vascular cognitive impairment in patients with acute cerebral infarction by Meta-analysis, and provide references for the effective prevention of the cognitive impairment in stroke patients. <strong>Methods:</strong> To retrieve the observational research literatures that refer to the risk factors of vascular cognitive impairment in patients with ischemic stroke, which are published on China National Knowledge Infrastructure (CNKI), Wanfang and Weipu Chinese databases. The screening and data extraction of these literatures are independently completed by two researchers, who also give the quality evaluation of the literatures according to the evaluation criterion of the Australian JBI Evidence-Based Health Care Center. Then, Meta-analysis is conducted by using Revman5.3 software. <strong>Results:</strong> There are twenty-eight articles selected from 1507 literatures, with a total of 10,711 cases and 50 risk factors included. Among them, there are combined effects of ten factors which have statistical significance, such as infarction area, alcohol consumption, smoking, hyper homocysteinemia, hypertension, diabetes mellitus, age, history of cerebral infarction, hyperlipoidemia and education level. The relational merging OR value and 95% CI between the type-variable factors and cognitive impairment are 3.25 (1.84, 5.76);2.98 (2.58, 3.45);2.79 (1.69, 4.59);2.35 (1.93, 2.85);2.25 (1.86, 2.71);2.14 (2.10, 2.18);1.82 (1.62, 2.03);1.54 (1.24, 1.92);1.45 (1.34, 1.56);0.83 (0.78, 0.89). <strong>Conclusion: </strong>Infarction area, alcohol consumption, smoking, hyper homocysteinemia, hypertension, diabetesmellitus, age, history of cerebral infarction, hyperlipoidemia and low education level are the main risk factors for vascular cognitive impairment in patients with acute cerebral infarction. Clinical nursing staff should include it into the routine assessment of patients with acute cerebral infarction and actively prevent and intervene.
基金supported by the Inaugural Anesthesia Department Awards for Seed Funding for ClinicallyOriented Research Projects from the Department of Anesthesia and Perioperative Care,University of California San Francisco,San Francisco,California (to Dr.Meng)
文摘Cerebral ischemia is the pathophysiological condition in which the oxygenated cerebral blood flow is less than what is needed to meet cerebral metabolic demand.It is one of the most debilitating complications in the perioperative period and has serious clinical sequelae.The monitoring and prevention of intraoperative cerebral ischemia are crucial because an anesthetized patient in the operating room cannot be neurologically assessed.In this paper,we provide an overview of the definition,etiology,risk factors,and prevention of cerebral ischemia during surgery.
文摘目的:分析高血压脑出血术后肺部感染危险因素。方法:检索中国知网、万方、维普、PubMed、EMBASE、Web of Science和Cochrane Library有关危险因素相关研究。检索时限从建库至2024年4月,筛选符合要求的文献,并进行质量评价和提取相比值比(OR)及95%CI,采用RevMan5.4软件进行Meta分析。结果:有13篇文献符合要求,共计689例高血压脑出血患者。通过Meta分析后认为危险因素包括吸烟史、糖尿病、低蛋白血症、机械通气时间、侵入性操作、气管切开、GCS<8、鼻饲;描述性分析结果显示:年龄、GCS与术后发生肺部感染有关。结论:高血压脑出血肺部感染危险因素较多,尽早识别危险因素,采取相关防治措施,有利于降低肺部感染发病率。
