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Stem cell transplantation in cerebrovascular accidents:A global bibliometric analysis(2000-2023)
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作者 Jad El Masri Ahmad Afyouni +7 位作者 Maya Ghazi Karim Hamideh Israe Moubayed Abdo Jurjus Hanine Haidar Ruzanna Petrosyan Pascale Salameh Hassan Hosseini 《World Journal of Stem Cells》 SCIE 2024年第9期832-841,共10页
BACKGROUND Cerebrovascular accident(CVA)is a major global contributor to death and disability.As part of its medical management,researchers have recognized the importance of promising neuroprotective strategies,where ... BACKGROUND Cerebrovascular accident(CVA)is a major global contributor to death and disability.As part of its medical management,researchers have recognized the importance of promising neuroprotective strategies,where stem cell transplantation(SCT)is thought to confer advantages via trophic and neuroprotective effects.AIM To evaluate the current state of research on SCT in patients with CVA,assess key trends and highlight literature gaps.METHODS PubMed was screened for SCT in CVA-related articles in October 2023,for each country during the period between 2000 and 2023.Using the World Bank data,total population and gross domestic product were collected for comparison.VOSviewer_1.6.19 was used to create the VOS figure using the results of the same query.Graphs and tables were obtained using Microsoft Office Excel.RESULTS A total of 6923 studies were identified on SCT in CVA,making 0.03%of all published studies worldwide.Approximately,68%were conducted in high-income countries,with a significant focus on mesenchymal stem cells.The journal“Stroke”featured the largest share of these articles,with mesenchymal SCT having the highest rate of inclusion,followed by hematopoietic SCT.Over time,there has been a noticeable shift from in vitro studies,which assess stem cell proliferation and neurogenesis,to in vivo studies aimed at evaluating efficacy and safety.Additionally,the number of reviews increased along this approach.CONCLUSION This bibliometric analysis provides a comprehensive guide for physicians and researchers in the field through an objective overview of research activity,and highlights both current trends and gaps.Having a potential therapeutic role in CVA,more research is needed in the future to focus on different aspects of SCT,aiming to reach a better treatment strategy and improve life quality in patients. 展开更多
关键词 Bibliometric analysis PUBMED Stem cell transplantation cerebrovascular accidents STROKE
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Stroke (Cerebrovascular Accident): Epidemiological, Clinical and Evolving Aspects in the Internal Medicine Department of the Public Health Establishment 1 (EPS1) of Tivaouane
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作者 Fulgence Abdou Faye Bachir Mansour Diallo +8 位作者 Awa Ba Amina Dia Guèye Abdou Khadre Mbaye Zeinabou Marone Adama Berthé Papa Soulèyemane Touré Madoky Magatte Diop Bernard Marcel Diop Mamadou Mourtalla Ka 《Open Journal of Internal Medicine》 2023年第4期313-329,共17页
Introduction: The frequency, severity, cost of treatment, morbidity and mortality of stroke make it a real public health problem. In industrialized countries, strokes are the leading cause of physical disability in ad... Introduction: The frequency, severity, cost of treatment, morbidity and mortality of stroke make it a real public health problem. In industrialized countries, strokes are the leading cause of physical disability in adults, the second leading cause of dementia (after Alzheimer’s disease), and the third leading cause of death (after cancer and cardiovascular disease). It’s also a major cause of depression. The objective of our study was to describe the epidemiological, clinical and evolutionary aspects of stroke in the internal medicine department of Tivaouane Hospital. Material and Method: This is a retrospective study carried out from January 1, 2015 to December 31, 2018 on the files of patients hospitalized for stroke in the medical department of the EPS1 in Tivaouane. We took into account all the patients who had a brain CT (computed tomography) scan. We collected data related to socio-demographic characteristics, history, risk factors, reasons for admission, clinical signs, paraclinical examinations, as well as evolution. Results: Out of 1999 patients, 206 files of patients with stroke were collected, i.e. a proportion of 10.3%. Our study population had a mean age of 65.53 years [16 - 97 years]. We noted a clear predominance of women (50.5%). The majority of the population came from the outskirts of Tivaouane (56.7%). Risk factors for stroke were dominated by hypertension (90.3%), dyslipidemia (19.4%), previous stroke (18.9%), and diabetes (16%). The clinical signs were dominated by a motor deficit (94.1%), speech disorders (67.4%) and consciousness disorders (47%). Ischemic strokes were predominant (65%) over hemorrhagic strokes (34.5%). The outcome was generally unfavorable with 14.6% total recovery, 58.7% recovery with sequelae and a case fatality of 26.7%. Conclusion: It emerges from this study that strokes still remain a real public health problem. Knowledge of populations of risk factors as well as their proper management is fundamental in primary prevention strategies, the only guarantee for a reduction in the still very high morbidity and mortality of this disease. 展开更多
关键词 cerebrovascular accident EPIDEMIOLOGY Risk Factors Tivaouane EPS1
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Medical Direct Cost of Hospital Admission for Cerebrovascular Accident on Medical Recovery at the Sylvanus Olympio Teaching Hospital of Lomé 被引量:2
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作者 Abago Balaka Toyi Tchamdja +3 位作者 Kodjo Agbéko Djagadou Hamadi Assane Komi Dzidzonu Némi Mohaman Awalou Djibril 《Open Journal of Internal Medicine》 2017年第4期165-171,共7页
Objectives: Appreciate the Medical direct cost for cerebrovascular accident on medical recovery at the Sylvanus Olympio Teaching Hospital of Lomé. Patients and method: This was a prospective and cross study that ... Objectives: Appreciate the Medical direct cost for cerebrovascular accident on medical recovery at the Sylvanus Olympio Teaching Hospital of Lomé. Patients and method: This was a prospective and cross study that took place from 01st October 2015 to 31st July 2016 in the medical recovery Unit of Sylvanus Olympio Teaching Hospital of Lomé. Results: Of the 91 stroke patients surveyed, the average age was 55.1 years;the sex-ratio (Men/women) was 1.3 and only 8.8% of patients had benefited from INAM (National Institute of Health Insurance) granting of benefits. The proportion of ICVA was 73.6% compared to 26.4% for the MCVA. The average overall cost of granting benefits of a CVA patient was 312,245 FCFA for an average stay of 18.6 days. This cost was 399.115 FCFA in MCVA for an average stay of 19.0 days against 281.130 FCFA in ICVA for an average stay of 16.1 days. Conclusion: CVAs on the one hand inflict losses of national productivity by its handicap, and a heavy economic burden for both patients and their families on the other hand, by its high cost of granting of benefits;Hence there is the need for assistance of all kinds by national and international health actors. 展开更多
关键词 cerebrovascular accidents Cost Granting of BENEFITS Sylvanus Olympio Teaching HOSPITAL of Lomé TOGO
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RESEARCH ON SEQUELAE OF CEREBROVASCULAR ACCIDENT TREATED BY THREE DIFFERENT NEEDLING TECHNIQUES
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《World Journal of Acupuncture-Moxibustion》 1994年第2期10-15,共6页
One hundred and sixty cases of sequelae of cerebrovascular accident (CVA) wererandomly divided into three groups: The temporal point group (TG), 58 cases; the scalp acupuncturegroup(SG), 52 cases; the body acupuncture... One hundred and sixty cases of sequelae of cerebrovascular accident (CVA) wererandomly divided into three groups: The temporal point group (TG), 58 cases; the scalp acupuncturegroup(SG), 52 cases; the body acupuncture group(BG), 50 cases. It was shown that after 30 treat-ments the curative effects were significantly different (P【0. 01) among the three groups. The effectin TG was better than those in SG and BG. There was no difference in curative effects between SGand BG. It is indicated that all the three needling techniques can improve encephalic blood flow in pa-tients. It seems that the effects of the three needling techniques are as follows: TG】SG】BG. 展开更多
关键词 cerebrovascular accident SEQUELAE Temporal point SCALP ACUPUNCTURE Body ACUPUNCTURE
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Predictors of a Cerebrovascular Accident in a Population of Systemic Sclerosis Patients Followed at a Large Academic Center with a Dedicated Scleroderma Center
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作者 Christopher J. Inserra Chris T. Derk 《Open Journal of Rheumatology and Autoimmune Diseases》 2020年第2期45-56,共12页
Aim: The aim of this study is to describe the clinical characteristics of patients with a diagnosis of systemic sclerosis who later suffer a stroke and to identify associations for this relationship. Background: Prior... Aim: The aim of this study is to describe the clinical characteristics of patients with a diagnosis of systemic sclerosis who later suffer a stroke and to identify associations for this relationship. Background: Prior studies have showed an increased risk of cardiovascular disease among patients with chronic inflammatory disorders, with chronic inflammation leading to atherosclerosis believed to be the culprit. Systemic sclerosis (SSc) is a chronic inflammatory disease characterized by diffuse fibrosis of the skin and internal organs. Previous studies have suggested a possible link between systemic sclerosis and macrovascular complications such as stroke. Methods: This is a retrospective chart review of patients treated within the University of Pennsylvania Health System from October 2015 to April 2019 with a diagnosis of SSc. Using ICD10 codes, we identified a cohort of SSc patients who suffered a stroke. Information regarding demographics and stroke risk factors were gathered from the charts of patients with a diagnosis of both SSc plus stroke and compared to a control group of randomly selected patients with SSc who never suffered a stroke. Continuous variables were conveyed using a mean plus a standard deviation. A two-sample t-test was used to compare the two groups of patients. Qualitative variables were compared using a two-tailed Fisher’s exact test. Results: Based on a large cohort of SSc patients (n = 2080) followed between October 2015 and April 2019, we identified 36 SSc patients who developed a subsequent stroke (1.7% of cohort). When looking at risk factors for stroke in SSc patients, we identified hypertension and atrial fibrillation to be associated with the diagnosis of stroke in such patients. Specifically, 28 of the 36 patients with both SSc and stroke also had a diagnosis of hypertension while in the control group, only 17 of 36 patients had hypertension. Atrial fibrillation was seen in 9 of 36 patients with both SSc and CVA while it was seen in only 2 of 36 patients in the control group. Conclusions: This case control study demonstrated that the presence of hypertension and atrial fibrillation had a statistically significant association with the diagnosis of CVA in patients with SSc. 展开更多
关键词 Systemic SCLEROSIS SCLERODERMA Stroke cerebrovascular accident ATRIAL FIBRILLATION Hypertension
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Acupuncture combined with Buyang Huanwu decoction in the treatment of sequelae of cerebrovascular accident:a systematic review and meta-analysis
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作者 Shao-Fu Yu Yun-Yun Wang +5 位作者 Qi-Yuan He Lei Zhang Ying-Hui Jin Bo-Xuan Liu Jian-Ping Gong Li-Ming Tan 《TMR Non-Drug Therapy》 2020年第3期101-124,共24页
Background:Cerebrovascular accident has high morbidity,high disability,and high mortality,possibly causing several serious sequelae and bringing a heavy burden to the patient,the family,and the society.Buyang Huanwu d... Background:Cerebrovascular accident has high morbidity,high disability,and high mortality,possibly causing several serious sequelae and bringing a heavy burden to the patient,the family,and the society.Buyang Huanwu decoction,a classic ancient prescription of traditional Chinese medicine,and acupuncture are often used in combination to treat the sequelae of cerebrovascular accident.In the present study,we systematically evaluated the clinical efficacy and safety of acupuncture combined with Buyang Huanwu decoction in treating the sequelae of cerebrovascular accident.Methods:Relevant randomized controlled trials of acupuncture combined with Buyang Huanwu decoction in treating the sequelae of cerebrovascular accident were comprehensively retrieved from electronic databases from inception to May 8,2020,including PubMed,Embase,The Cochrane Library,China National Knowledge Infrastructure,WanFang Data,and China Science and Technology Journal Database.The main outcomes of clinical efficacy,degree of nerve function impairment,daily self-care capacity,Fugl-Meyer locomotor function score,life quality score,and occurrence of adverse reactions were subjected to meta-analysis.Results:The 28 randomized controlled trials included 2,341 patients with the sequelae of cerebrovascular accident.Systematic review and meta-analysis indicated that compared with acupuncture alone,its combined treatment with Buyang Huanwu decoction significantly increased clinical efficacy(RR=1.19,95%CI(1.14,1.23),P<0.001),improved nerve function impairment(WMD=−4.89,95%CI(−8.25,−1.53),P=0.004),promoted daily self-care capacity(WMD=15.87,95%CI(11.22,20.51),P<0.001),strengthened Fugl-Meyer locomotor function(WMD=20.89,95%CI(13.79,27.98),P<0.001),enhanced physical functioning(WMD=16.99,95%CI(6.01,27.96),P<0.001)and mental health(WMD=16.91,95%CI(9.14,24.69),P<0.001)in terms of life quality score(SF-36 scale)of patients with sequelae of cerebrovascular accident,with few adverse reactions.Conclusion:Compared with acupuncture alone,its combination with Buyang Huanwu decoction had better comprehensive effects on sequelae of cerebrovascular accident without obvious adverse reactions. 展开更多
关键词 ACUPUNCTURE Buyang Huanwu decoction Sequelae of cerebrovascular accident Randomized controlled trials Clinical efficacy Nerve function
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Traumatic Brain Injury and Cerebral Vascular Accident: Application of Rasch Analysis to Examine Differences in Disability and Outcome in Post-Hospital Rehabilitation
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作者 Frank D. Lewis Gordon J. Horn 《Open Journal of Statistics》 2018年第4期670-683,共14页
The purpose of this study was to demonstrate an application of Rasch analysis to identify differences in disability profiles resulting from traumatic brain injury (TBI) and cerebral vascular accident (CVA) and to exam... The purpose of this study was to demonstrate an application of Rasch analysis to identify differences in disability profiles resulting from traumatic brain injury (TBI) and cerebral vascular accident (CVA) and to examine outcome differences between the two groups following post-hospital residential rehabilitation. Participant data were collected from 32 facilities in 16 states. From 2990 neurologically impaired individuals with consecutive admissions from 2011 through 2017, 874 met inclusion criteria: TBI (n = 687) or CVA (n = 187), 18 years or older, minimum length of stay of one month, and maximum chronicity of 1 year. Participants were evaluated at admission and discharge on the Mayo Portland Adaptability Inventory-Version 4 (MPAI-4). Rasch analysis was performed to establish item reliability, construct validity and item difficulty. A Repeated Measures Multivariate Analysis of Covariance (RM MANCOVA) determined group differences and improvement from admission and discharge. Rasch Analysis demonstrated satisfactory construct validity and internal consistency (Person reliability > 0.90, Item reliability > 0.98 for admission and discharge MPAI-4s). Both groups showed significant improvement on the MPAI-4 (p 0.0005). The TBI group was more impaired on the adjustment scale at both admission and discharge (p 0.001). Rasch analysis identified two distinct impairment patterns. CVA participants exhibited deficits characteristic of focal impairment while the TBI group presented with deficits reflective of diffuse impairment. Rehabilitation was shown to be beneficial in reducing disability following neurologic injury in both groups. Importantly, Rasch Analysis accurately produced unique disability profiles that differentiated the treatment groups. This unique statistical technique offers a promising prescriptive hierarchical model for guiding neurological rehabilitation treatment. 展开更多
关键词 Traumatic Brain Injury TBI cerebrovascular accident CVA Stroke OUTCOME Post-Hospital Rehabilitation MPAI-4 RASCH Analysis Functional Assessment
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鼻肠管及鼻胃管的营养干预护理对脑血管意外患者发生吸入性肺炎并发症及睡眠质量的影响
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作者 周彩丽 《世界睡眠医学杂志》 2024年第7期1581-1584,共4页
目的:探讨研究脑血管意外患者用鼻肠管营养干预效果。方法:选取2021年4月至2022年4月厦门大学附属第一医院神经内科收治的脑血管意外患者100例作为研究对象,按照随机数字表法分为对照组和观察组,每组50例。2组患者均予以常规护理,对照... 目的:探讨研究脑血管意外患者用鼻肠管营养干预效果。方法:选取2021年4月至2022年4月厦门大学附属第一医院神经内科收治的脑血管意外患者100例作为研究对象,按照随机数字表法分为对照组和观察组,每组50例。2组患者均予以常规护理,对照组给予常规鼻胃管营养干预,观察组给予鼻肠管营养干预。比较2组患者的吸入性肺炎发生率、睡眠质量评分及营养状况。结果:观察组吸入性肺炎发生率低于对照组,差异有统计学意义(P<0.05);观察组入睡潜伏期、PSQI评分低于对照组,实际睡眠时长高于对照组,差异有统计学意义(P<0.05);观察组血红蛋白(Hb)、血清白蛋白(Alb)、血清总蛋白(TP)均高于对照组,差异有统计学意义(P<0.05)。结论:鼻肠管营养干预护理可降低脑血管意外患者吸入性肺炎发生率,改善患者睡眠质量及营养状况,值得临床推广应用。 展开更多
关键词 鼻肠管 鼻胃管 营养干预护理 脑血管意外 吸入性肺炎 睡眠质量
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颞浅动脉-大脑中动脉分支吻合术治疗闭塞性脑血管疾病的临床效果
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作者 付增彬 秦立鹏 +4 位作者 李尧 李普阳 王凯 赵亚鹏 高雪亮 《局解手术学杂志》 2024年第1期80-84,共5页
目的探讨颞浅动脉-大脑中动脉分支吻合术(STA-MCA)治疗闭塞性脑血管疾病的临床效果。方法纳入我院收治的74例闭塞性脑血管疾病患者,根据随机数字表法分为观察组与对照组,每组37例。对照组患者采用保守治疗,观察组患者采用STA-MCA治疗。... 目的探讨颞浅动脉-大脑中动脉分支吻合术(STA-MCA)治疗闭塞性脑血管疾病的临床效果。方法纳入我院收治的74例闭塞性脑血管疾病患者,根据随机数字表法分为观察组与对照组,每组37例。对照组患者采用保守治疗,观察组患者采用STA-MCA治疗。术后随访3个月,观察2组治疗前和治疗后第3天、1个月、3个月的脑血流指标(大脑前动脉脑血流量、达峰时间),记录2组患者治疗前和治疗后第3天、1个月改良Rankin评分,统计治疗后血管重建情况和并发症发生情况。结果2组患者治疗后1个月、3个月的大脑前动脉脑血流量均提高,达峰时间均缩短,且观察组患者大脑前动脉脑血流量高于对照组,达峰时间短于对照组,差异有统计学意义(P<0.05)。与治疗前比较,2组患者治疗后1个月改良Rankin评分均降低,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组患者治疗后1个月血管重建为0级、1级的比例低于对照组,2级、3级比例高于对照组,差异均有统计学意义(P<0.05);观察组患者治疗后3个月血管重建为0级、1级比例低于对照组,3级比例高于对照组,差异均有统计学意义(P<0.05)。2组患者治疗后并发症总发生率比较,差异无统计学意义(P>0.05)。结论STA-MCA治疗闭塞性脑血管疾病的临床效果良好,有利于改善脑血流指标,促进神经功能恢复和血管重建,安全可靠。 展开更多
关键词 闭塞性脑血管疾病 颞浅动脉-大脑中动脉分支吻合术 脑血流量 改良Rankin评分 并发症
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脑卒中患病影响因素的研究现状
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作者 鞠柠蔚 蒋红 +3 位作者 宋润琛 闫琴琴 熊明钰 高怡萌 《中外医学研究》 2024年第14期165-171,共7页
随着脑卒中的发病率逐年升高,给社会、家庭和患者带来了巨大的痛苦、经济压力和社会负担,因而加强其疾病因素的分类、研究和预警,对降低发病率和死亡率具有重要意义。因此,本文从不可控因素(年龄、性别、遗传、环境等)、疾病因素(高血... 随着脑卒中的发病率逐年升高,给社会、家庭和患者带来了巨大的痛苦、经济压力和社会负担,因而加强其疾病因素的分类、研究和预警,对降低发病率和死亡率具有重要意义。因此,本文从不可控因素(年龄、性别、遗传、环境等)、疾病因素(高血压、糖尿病、高血脂、冠心病、偏头痛等)、个人因素(生活习惯、心理因素、睡眠因素等)、其他因素等方面对脑卒中发病的影响因素进行综述,以期为脑卒中的预防、治疗和护理提供依据。 展开更多
关键词 脑卒中 发病 影响因素 综述
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基于FMEA模型的预见性护理在脑血管介入术患者中的应用
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作者 龚俊 苗锐 +1 位作者 李露 成毅 《海南医学》 CAS 2024年第10期1499-1503,共5页
目的研究基于失效模式和效应分析(FMEA)模型的预见性护理在脑血管介入术患者中的应用效果。方法前瞻性选取2021年1月至2023年12月在陕西省第二人民医院拟接受脑血管介入术治疗的102例患者作为研究对象,按随机数表法分为观察组和对照组... 目的研究基于失效模式和效应分析(FMEA)模型的预见性护理在脑血管介入术患者中的应用效果。方法前瞻性选取2021年1月至2023年12月在陕西省第二人民医院拟接受脑血管介入术治疗的102例患者作为研究对象,按随机数表法分为观察组和对照组各51例,对照组患者采用常规护理,观察组患者在对照组护理的基础上采用基于FMEA模型的预见性护理。持续护理至患者出院,比较两组患者的置管时间、卧床时间、住院时间以及ICU入住情况;分别于术前、出院时,比较两组患者的D-二聚体(D-D)、超敏C反应蛋白(hs-CRP)水平;出院时采用自制调查问卷调查两组患者和护理满意度;出院时,统计分析两组患者并发症发生情况,并采用生活质量评价量表(SF-36)评估两组患者术后生活质量恢复情况。结果观察组患者的置管时间、卧床时间、住院时间、ICU入住率分别为(4.67±0.78)d、(3.63±1.74)d、(9.67±1.45)d、3.92%,明显短(低)于对照组的(6.39±1.24)d、(5.53±1.26)d、(13.39±2.25)d、21.57%,差异均有统计学意义(P<0.05);术前,两组患者D-D、hs-CRP比较差异均无统计学意义(P>0.05);出院时,观察组患者的D-D、hs-CRP水平分别为(0.29±0.15)mg/L、(3.48±0.45)mg/L,明显低于对照组的(0.57±0.44)mg/L、(6.97±1.40)mg/L,差异均有统计学意义(P<0.05);出院时观察组患者对护理的总满意度为94.12%,明显高于对照组的80.39%,差异有统计学意义(P<0.05);出院时,观察组患者的并发症总发生率为5.88%,明显低于对照组的29.41%,观察组患者SF-36各项得分明显高于对照组,差异均有统计学意义(P<0.05)。结论基于FMEA模型的预见性护理可显著降低脑血管介入术后患者的并发症发生率,促进改善患者临床结局,提升患者护理满意度。 展开更多
关键词 失效模式 效应分析 脑血管介入术 并发症 预见性护理
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Aspirin interruption before neurosurgical interventions:A controversial problem
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作者 Alexander Kulikov Anton Konovalov +1 位作者 Pier Paolo Pugnaloni Federico Bilotta 《World Journal of Cardiology》 2024年第4期191-198,共8页
Aspirin is widely used for primary or secondary prevention of ischemic events.At the same time,chronic aspirin consumption can affect blood clot formation during surgical intervention and increase intraoperative blood... Aspirin is widely used for primary or secondary prevention of ischemic events.At the same time,chronic aspirin consumption can affect blood clot formation during surgical intervention and increase intraoperative blood loss.This is especially important for high-risk surgery,including neurosurgery.Current European Society of Cardiology guidelines recommend aspirin interruption for at least 7 d before neurosurgical intervention,but this suggestion is not supported by clinical evidence.This narrative review presents evidence that challenges the necessity for aspirin interruption in neurosurgical patients,describes options for aspirin effect monitoring and the clinical implication of these methods,and summarizes current clinical data on bleeding risk associated with chronic aspirin therapy in neurosurgical patients,including brain tumor surgery,cerebrovascular procedures,and spinal surgery. 展开更多
关键词 ASPIRIN NEUROSURGERY Postoperative complications Bleeding risk Brain tumor surgery cerebrovascular surgery Spinal surgery
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Information-motivation-behavioral guided nursing for stroke patients with pulmonary dysfunction:A randomized controlled trial
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作者 Xia Peng Hui-Qin Ni +2 位作者 Yong-Mei Liu Jin-Ling Zhu Yu-Ting Bai 《World Journal of Clinical Cases》 SCIE 2024年第24期5549-5557,共9页
BACKGROUND Patients with stroke frequently experience pulmonary dysfunction.AIM To explore the effects of information-motivation-behavioral(IMB)skills modelbased nursing care on pulmonary function,blood gas indices,co... BACKGROUND Patients with stroke frequently experience pulmonary dysfunction.AIM To explore the effects of information-motivation-behavioral(IMB)skills modelbased nursing care on pulmonary function,blood gas indices,complication rates,and quality of life(QoL)in stroke patients with pulmonary dysfunction.METHODS We conducted a controlled study involving 120 stroke patients with pulmonary dysfunction.The control group received routine care,whereas the intervention group received IMB-model-based nursing care.Various parameters including pulmonary function,blood gas indices,complication rates,and QoL were assessed before and after the intervention.RESULTS Baseline data of the control and intervention groups were comparable.Post-intervention,the IMB model-based care group showed significant improvements in pulmonary function indicators,forced expiratory volume in 1 sec,forced vital capacity,and peak expiratory flow compared with the control group.Blood gas indices,such as arterial oxygen pressure and arterial oxygen saturation,increased significantly,and arterial carbon dioxide partial.pressure decreased significantly in the IMB model-based care group compared with the control group.The intervention group also had a lower complication rate(6.67%vs 23.33%)and higher QoL scores across all domains than the control group.CONCLUSION IMB model-based nursing care significantly enhanced pulmonary function,improved blood gas indices,reduced complication rates,and improved the QoL of stroke patients with pulmonary dysfunction.Further research is needed to validate these results and to assess the long-term efficacy and broader applicability of the model. 展开更多
关键词 cerebrovascular accident rehabilitation Respiratory function tests Nursing methodology research Behavioral medicine Quality of life
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经食管超声心动图建立卵圆孔未闭致病风险因素模型
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作者 马亚利 徐艳 +3 位作者 赵蓓 王慧 陈允安 范乐乐 《河北医药》 CAS 2024年第19期3018-3021,共4页
目的分析致病性卵圆孔未闭(PFO)的危险因素并构建风险评估模型,为制订临床护理方案提供依据。方法回顾性分析2022年7月至2023年7月徐州医科大学附属连云港医院收治的110例PFO患者临床资料,根据是否发生隐匿性脑血管意外(CVA)分为CVA组4... 目的分析致病性卵圆孔未闭(PFO)的危险因素并构建风险评估模型,为制订临床护理方案提供依据。方法回顾性分析2022年7月至2023年7月徐州医科大学附属连云港医院收治的110例PFO患者临床资料,根据是否发生隐匿性脑血管意外(CVA)分为CVA组42例和非CVA组68例。收集患者临床资料及经食管超声心动图评估参数,采用单因素和多因素Logistic回归分析PFO患者发生CVA的危险因素并建立风险预测模型,通过绘制ROC曲线评价模型的预测效能。结果CVA组和非CVA组在高血压病、高脂血症、房间隔膨出瘤、房间隔高移动性发生率以及甘油三酯、半胱氨酸、PFO高度、PFO隧道长度等指标的差异有统计学意义(P<0.05)。以是否发生CVA作为因变量,将单因素分析中有统计学意义的指标作为自变量进行多因素Logistic回归分析,结果显示,高脂血症、PFO高度、房间隔膨出瘤、房间隔高移动性是PFO患者发生CVA的独立危险因素(P<0.05)。根据多因素分析结果,建立CVA风险预测模型为:Logit(P)=-2.613+1.442×高脂血症+2.610×PFO高度+1.194×房间隔膨出瘤+1.309×房间隔高移动性,模型中变量的意义分别为:高脂血症(0=无,1=是),PFO高度为实际测量值,房间隔膨出瘤(0=无,1=是),房间隔高移动性(0=无,1=是)。Hosmer-Lemeshow检验的P>0.05,说明预测模型的预测值与实际值差异无统计学意义,模型拟合优度较好。以CVA预测概率作为检验变量进行ROC分析,结果显示该预测模型的曲线下面积为0.866(95%CI:0.787~0.923,P<0.01),最佳临界值为0.635,特异性为77.9%,敏感性为81.0%,约登指数为0.589。结论基于危险因素建立的风险预测模型能预测PFO发生CVA风险,可成为医护人员评估有PFO致病风险的工具,有利于护理人员制订个体化的护理决策。 展开更多
关键词 卵圆孔未闭 不明原因脑血管意外 经食管超声心动图
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Acute Colonic Pseudo-Obstruction (ACPO): An Expanding Colon with Unusual Risk Factors
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作者 Kelly Schulte Alyson Terry +1 位作者 Grace Boyle Dmitriy Scherbak 《Open Journal of Internal Medicine》 2024年第2期167-174,共8页
The distention of the colon without mechanical or anatomical obstruction, Acute Colonic Pseudo-obstruction (ACPO), is a common condition occurring in the critically ill. ACPO in the setting of an acute pulmonary embol... The distention of the colon without mechanical or anatomical obstruction, Acute Colonic Pseudo-obstruction (ACPO), is a common condition occurring in the critically ill. ACPO in the setting of an acute pulmonary embolism and embolic stroke is a rarity. A 76-year-old female with shortness of breath, left hemiparesis and right-sided paresthesias presented with acute pulmonary embolism and acute infarcts of the left caudate nucleus, thalamus and occipital lobe. Her hospitalization was complicated with persistent distention of the large bowel without dilation of the small bowel. Empiric antibiotics were initiated without improvement and laboratory studies including Clostridium difficile were negative. She underwent nasogastric decompression and two decompressive colonoscopies with a resolution of her symptoms. This case illustrates an example of acute abdominal distension, without underlying etiology, in the setting of acute embolism of the pulmonary and cerebral vasculature. Early identification and action with decompressive colonoscopy were key to preventing further bowel damage or rupture. 展开更多
关键词 Acute Colonic Pseudo-Obstruction ACPO Ogilvie’s Syndrome Colonic Dilation Acute Embolic Infarcts cerebrovascular accident Pulmonary Embolism PE
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重症脑血管病患者早期气管切开的护理关键要素探究
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作者 王延珍 张铭新 程玉花 《中外医疗》 2024年第15期128-131,共4页
目的 分析重症脑血管病患者在针对早期气管切开时的护理要素。方法 本研究便利选取2021年10月—2023年5月济南市济阳区中医院收治的91例行早期气管切开的重症脑血管病患者为研究对象。依据护理方法分为两组,对照组(n=45)采用常规护理模... 目的 分析重症脑血管病患者在针对早期气管切开时的护理要素。方法 本研究便利选取2021年10月—2023年5月济南市济阳区中医院收治的91例行早期气管切开的重症脑血管病患者为研究对象。依据护理方法分为两组,对照组(n=45)采用常规护理模式,观察组(n=46)采用综合护理模式,比较两组患者的生活质量、并发症发生情况和护理满意度。结果 护理前,两组患者生活质量评分比较,差异无统计学意义(P>0.05);护理后,观察组生活质量评分高于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为4.35%,低于对照组的20.00%,差异有统计学意义(χ^(2)=5.244,P<0.05)。观察组护理总满意度为97.83%,高于对照组的82.22%,差异有统计学意义(χ^(2)=4.587,P<0.05)。结论 针对重症脑血管病患者早期气管切开时采用综合护理可以提高患者的生活质量,减少患者并发症发生,进一步提高患者的满意度。 展开更多
关键词 重症脑血管病 早期气管切开 生活质量 并发症 护理满意度
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综合性康复疗法治疗脑血管意外偏瘫的临床疗效评价
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作者 李仲敏 《中外医疗》 2024年第12期54-57,共4页
目的分析脑血管意外偏瘫患者使用综合性康复疗法的临床疗效。方法方便选择宁津县人民医院于2021年8月—2023年6月收治的106例脑血管意外偏瘫患者作为研究对象,以随机数表法分为对照组和观察组,每组53例。对照组采用常规康复疗法,观察组... 目的分析脑血管意外偏瘫患者使用综合性康复疗法的临床疗效。方法方便选择宁津县人民医院于2021年8月—2023年6月收治的106例脑血管意外偏瘫患者作为研究对象,以随机数表法分为对照组和观察组,每组53例。对照组采用常规康复疗法,观察组采用综合性康复疗法,对比两组临床疗效、肢体运动功能评分、日常生活能力评分、神经功能缺损程度评分。结果治疗后,观察组临床总疗效(94.34%)高于对照组(79.25%),差异有统计学意义(χ^(2)=5.267,P<0.05);观察组肢体运动功能评分、日常生活能力评分、神经功能缺损程度评分均优于对照组,差异有统计学意义(P均<0.05)。结论综合性康复疗法对于提升脑血管意外偏瘫的临床疗效具有重要作用,且可以提升患者肢体运动功能、日常生活能力,改善神经功能缺损问题。 展开更多
关键词 脑血管意外 偏瘫 综合性康复疗法 临床疗效 日常生活能力 肢体运动功能
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血清Hcy及FGF-23预测血液透析治疗尿毒症合并高血压患者并发心脑血管事件的价值
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作者 柯婷雯 叶钊 +1 位作者 杜雅钦 郑烨焱 《国际医药卫生导报》 2024年第15期2500-2506,共7页
目的分析血清同型半胱氨酸(Hcy)、成纤维细胞生长因子-23(FGF-23)预测血液透析治疗尿毒症合并高血压患者并发心脑血管事件的价值。方法回顾性分析,选取2019年2月至2022年12月在黄石市中医医院收治的98例行血液透析治疗的尿毒症合并高血... 目的分析血清同型半胱氨酸(Hcy)、成纤维细胞生长因子-23(FGF-23)预测血液透析治疗尿毒症合并高血压患者并发心脑血管事件的价值。方法回顾性分析,选取2019年2月至2022年12月在黄石市中医医院收治的98例行血液透析治疗的尿毒症合并高血压患者的临床资料,其中男58例、女40例,年龄53~76(64.18±5.39)岁;另收集患者血清Hcy、FGF-23等临床资料,随访1年。统计随访期间患者发生心脑血管事件情况,采用t检验、χ^(2)检验及logistic回归分析影响血液透析治疗尿毒症合并高血压患者心脑血管事件发生的因素,并绘制受试者操作特征曲线(ROC)分析Hcy与FGF-23预测其发生心脑血管事件的价值。结果98例行血液透析治疗的尿毒症合并高血压患者中,有37例(37.76%)出现心脑血管事件,其余61例(62.24%)未出现心脑血管事件。两组患者性别、年龄、体质量指数、吸烟史、饮酒史、心率、高血压病程、收缩压、舒张压、降压药物使用种类、空腹血糖、三酰甘油、总胆固醇、高密度脂蛋白胆固醇、前白蛋白、转铁蛋白、尿素氮、肌酐、尿酸、血清丙氨酸转氨酶、γ-谷氨酰转移酶、血钙、血磷、总尿素清除指数、血甲状旁腺素、左室射血分数比较,差异均无统计学意义(均P>0.05);心脑血管事件组透析龄、血白蛋白、低密度脂蛋白胆固醇、尿白蛋白排泄率、红细胞分布宽度、Hcy、FGF-23均高于非心脑血管事件组[(4.83±0.81)年比(4.39±0.58)年、(36.33±5.08)g/L比(32.66±5.39)g/L、(3.59±0.75)mmol/L比(3.25±0.35)mmol/L、(38.77±4.43)mg/24 h比(35.54±4.41)mg/24 h、(15.59±2.19)%比(13.21±1.16)%、(18.82±2.31)μmol/L比(14.46±2.20)μmol/L、(189.71±32.69)ng/L比(154.59±27.68)ng/L],估算肾小球滤过率(eGFR)低于非心脑血管事件组[(40.56±7.12)ml/min/1.73m2比(46.37±6.23)ml/min/1.73 m2],差异均有统计学意义(t=3.126、3.388、3.043、3.509、7.303、9.333、5.683、4.239,均P<0.05)。logistic多因素回归分析显示,透析龄、Hcy、FGF-23、eGFR水平是影响血液透析治疗尿毒症合并高血压患者心脑血管事件发生的因素(均P<0.05)。ROC分析结果显示,Hcy、FGF-23及二者联合预测血液透析治疗尿毒症合并高血压患者发生心脑血管事件的灵敏度分别为71.68%、76.57%、78.04%,特异度分别为78.59%、74.31%、89.36%,曲线下面积(AUC)分别为0.768、0.745、0.886。结论血清Hcy、FGF-23水平与血液透析治疗尿毒症合并高血压患者并发心脑血管事件有关,Hcy、FGF-23处于高水平时心脑血管事件发生风险更高,二者联合预测血液透析治疗尿毒症合并高血压患者并发心脑血管事件效能较高。 展开更多
关键词 血液透析 尿毒症合并高血压 同型半胱氨酸 成纤维细胞生长因子-23 心脑血管疾病
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中医情志护理在脑血管局部麻醉介入患者术中的效果观察
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作者 李焕梅 黎梅 +2 位作者 裴姣 李超群 谢森 《中国医药科学》 2024年第16期89-92,共4页
目的 探究脑血管局部麻醉介入术者的护理,分析中医情志护理效果。方法 选择2022年6月至2023年8月阳春市中医院脑病科进行脑血管局部麻醉介入术患者100例为研究对象,随机分为两组,对照组50例,采用术中常规护理,观察组50例,采用术中中医... 目的 探究脑血管局部麻醉介入术者的护理,分析中医情志护理效果。方法 选择2022年6月至2023年8月阳春市中医院脑病科进行脑血管局部麻醉介入术患者100例为研究对象,随机分为两组,对照组50例,采用术中常规护理,观察组50例,采用术中中医情志护理,统计患者的负性情绪、并发症、疼痛评分、舒适度、满意度,实施比较分析。结果 护理后对照组负性情绪、并发症总发生率、疼痛评分高于观察组,差异有统计学意义(P <0.05)。护理后观察组舒适度评分、满意度高于对照组,差异有统计学意义(P <0.05)。结论 脑血管局部麻醉介入术中施以中医情志护理,效果显著,负性情绪、术后并发症减少,疼痛症状减轻,舒适度及满意度提高,应用价值显著。 展开更多
关键词 脑血管介入术 常规护理 中医情志护理 并发症发生率 舒适度
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头颅CT及磁共振成像在脑梗死后睡眠障碍患者中的应用价值研究
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作者 崔节敏 《世界睡眠医学杂志》 2024年第8期1910-1912,共3页
目的:分析头颅CT及磁共振成像在脑梗死后睡眠障碍患者中的应用价值。方法:选取2023年1月至2024年1月莘县人民医院收治的脑梗死患者80例作为研究对象,按照是否合并睡眠障碍分为对照组和观察组,每组40例。2组均接受头颅CT及磁共振检查,回... 目的:分析头颅CT及磁共振成像在脑梗死后睡眠障碍患者中的应用价值。方法:选取2023年1月至2024年1月莘县人民医院收治的脑梗死患者80例作为研究对象,按照是否合并睡眠障碍分为对照组和观察组,每组40例。2组均接受头颅CT及磁共振检查,回顾性总结2组睡眠质量、神经功能与影像学检查结果。结果:与对照组相较,观察组匹兹堡睡眠指数量表(PSQI)、美国国立卫生研究院卒中量表(NIHSS)评分更高(P<0.05)。2组患者梗死患侧分布情况比较,差异无统计学意义(P>0.05)。2组发病部位情况比较,观察组患者病灶多发情况高于对照组,差异有统计学意义(P<0.05)。结论:头颅CT与磁共振成像联合可充分为识别脑梗死患者的睡眠障碍提供依据,从而为睡眠障碍的诊断与治疗方案优化提供指导性策略。 展开更多
关键词 脑梗死 睡眠障碍 头颅CT 磁共振成像 睡眠质量 神经功能 脑血管疾病 并发症
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