Clinical pregnancy rate of women with unexplained infertility with or without cervical mucus aspiration before intrauterine insemination: A randomized controlled trial

Objective:To detect effect of removing cervical mucus before performing intrauterine insemination(IUI)on pregnancy rate in patients with unexplained infertility.Methods:The randomized controlled trial was conducted in Infertility Division of Department of Obstetrics and Gynaecology of a tertiary care hospital.Totally 80 patients of unexplained infertility were recruited.By computer generated block randomization in block size of 4 and 6,patients were randomly allocated at time of starting ovarian stimulation into the cervical mucus removal group or the non-removal of cervical mucus group before IUI,40 in each group.Ovarian stimulation with clomiphene 100 mg from day 2-6 of menstrual cycle along with human menopausal gonadotropin 150 IU was given alternate day starting from day 7.Follicular monitoring was done and further doses given as per response;trigger was planned when 1-3 follicle reach a diameter of>18 mm.IUI was planned after trigger.IUI was done as per the group allocated.Mucus cleaning was done in the cervical mucus removal group by aspirating mucus with IUI syringe and sterile cotton swab before IUI.The primary outcome was clinical pregnancy rate.Number of difficult IUIs and cycle cancellation due to ovarian hyperstimulation were also noted.Results:IUI was not done in 4 patients due to hyperstimulation.Pregnancies per IUI cycle occurred in 7.9%(3/38)in the cervical mucus removal group and 21.1%(8/38)in the non-removal of cervical mucus group.There was no statistically significant difference in clinical pregnancy rate between two groups(P=0.19).Conclusions:There is a trend towards a lower clinical pregnancy rate with removal of cervical mucus before IUI in women of unexplained infertility though the difference is not statistically significant.Further studies with large sample size need to be done on this intervention.

Evaluation of the quality of randomized controlled trials on exercise for cervical radiculopathy

Objective:To review and evaluate the quality of the randomized controlled trials of exercise for the treatment of cervical radiculopathy with the present internationally recognized CONSORT statement, which provides reference and basis for the improvement of clinical research on exercise for intervening cervical radiculopathy in the future.Methods: A computer-based search of large domestic databases, including CNKI, Wanfang database and VIP database screened out literature that meet the requirements and used CONSORT statement for quality assessment.Results: According to the prescribed inclusion and exclusion criteria, 30 articles were retrieved in accordance with the standard. No literature was referred to the randomized controlled trial, 2 documents clearly defined the type of test design, 1 documents carried out the calculation of sample size, 13 documents clearly randomly assigned, 1 literature implemented the blind method, in the 7 literature, baseline information was shown in tabular form, and no reference was made to trial registration, trial protocol and funding.Conclusion:There are some aspects of randomized controlled trials on exercise for the treatment of cervical radiculopathy. However, there are some aspects that need to be improved. In the future randomized controlled trial report, the CONSORT statement should be highly valued and carefully considered to improve the accuracy and credibility of the research.

Acupuncture of different stimulation for the treatment of neck type cervical spondylosis:a randomised controlled trial

Objective:To observe the difference in clinical efficacy of acupuncture with strong and weak stimulation in treating neck type cervical spondylosis.Methods:64 patients with neck type cervical spondylosis were randomly divided into strong stimulation group and weak stimulation group,with 32 cases in each group.The acupoints selected are Jingjiaji 5-7(cervical acupoints EX-B2 C5-C7),Tianzhu(BL10)on both sides,Houxi(SI3)on both sides,Hegu(LI4)on both sides,Geshu(BL17)on both sides,and Ashi.In the strong stimulation group,deep needling with 0.25 mm×40 mm milli-needle was performed,with a mild reinforcing-reducing method.The twisting angle was 90°-180°,the frequency was 60-90 times/min,and the needles were applied for 1 min at each point.Keep the needle for 30 minutes,twisting was performed every 10 min during the retention period.Change hands once.In the weak stimulation group,shallow acupuncture with a 0.18 mm×40 mm milli-needle was performed,with a mild reinforcing-reducing method,with a twisting angle of 60°-90°,a frequency of 30-60 times/min,and acupuncture for 10 seconds at each acupoint.Keep the needle for 30 minutes,and no needle during the retention period.Patients in both groups were treated once every 1 to 2 days,3 times a week for 2 weeks,and followed up for 1 month after all treatments.The two groups of patients were compared before and after treatment and during follow-up.The McGill pain questionnaire score and the cervical spine dysfunction index score were compared to determine the clinical efficacy.Statistical analysis was performed using SPSS 22.0 statistical software.Results:1 case drop-out in the strong stimulation group and 1 case in the weak stimulation group.The total effective rate of the strong stimulation group was 90.32%,the total effective rate of the weak stimulation group was 83.87%,and the total effective rate of the strong stimulation group was higher than that of the weak stimulation group(P<0.05).The total scores of the short-form McGill pain questionnaire,the VAS score,and the cervical spine dysfunction index scores of the two groups of patients were significantly lower than those of this group before treatment,and the difference was statistically significant(P<0.05).The total scores of the short-form McGill pain questionnaire,visual analogue scale score,and cervical spine dysfunction index scores of the strong stimulation group after treatment and follow-up were significantly lower than those of the weak stimulation group(P<0.05).Conclusion:Acupuncture with strong and weak stimulation can effectively treat patients with cervical spondylosis,and deep acupuncture with filiform needles and strong stimulation have better effect.

A multi-center randomized controlled clinical trial of three-step acupuncture and cupping therapy for cervicogenic headache

目的:观察三步针罐疗法治疗颈源性头痛的临床有效性和安全性。方法:采用随机、单盲、多中心平行对照临床试验方法,收集符合研究标准的颈源性头痛的患者63例,随机分为治疗组32例和对照组31例,治疗组采用三步针罐疗法治疗,对照组采用假针刺治疗。分别于治疗前、首次治疗后即刻、治疗10天后、治疗20天后、治疗结束3个月随访时观察两组患者的简化的McGill疼痛评分,包括三个部分:疼痛等级指数(PRI),视觉模拟评定(VAS)和现有痛强度(PPI)和头颈部僵硬感及颈椎活动度评定(ROM),并进行安全性评价。结果:与治疗前比较,两组治疗后各个观察时间点各项评分均有显著改善,在观察时间点各项评分方面,治疗组明显优于对照组;疗程结束后3个月随访时各项评分与治疗20天后评分比较,治疗组无显著性差异,对照组各项评分均有显著性差异,提示治疗组与对照组相比有较好的远期疗法。结论:三步针罐法与假针刺组比较,治疗颈源性头痛具有一定的近期疗效,见效快,近期疗效和远期疗效上均优于假针刺组,复发率低。

Qi-guiding Needling Based on Meridian Differentiation for Lumbar Disc Herniation: A Multi-centered, Randomized Controlled Trial

Objective: To observe the efficacy of acupoint selection by meridian differentiation plus qi-guiding needling in treating lumbar disc herniation(LDH). Methods: By using the random number table, 549 patients with LDH were randomized into two groups. Two hundred and eighty participants in the observation group were intervened by selecting acupoints by meridian differentiation associated with qi-guiding needling method, and the other 269 participants in the control group were by selecting acupoints by meridian differentiation plus electroacupuncture. At the end of intervention, the changes of conduction velocities of the common peroneal nerve, superficial peroneal nerve, and tibial nerve were observed, and the therapeutic efficacies were compared. Results: The total effective rate was 87.5% in the observation group versus 86.6% in the control group, and the difference was statistically insignificant(P>0.05). The recovery rate was 51.8% in the observation group versus 37.2% in the control group, and the difference was statistically significant(P<0.05). Conclusion: Selecting acupoints by meridian differentiation associated with qi-guiding needling can produce a similar total effective rate to selecting acupoints by meridian differentiation plus electroacupuncture, while its recovery rate is comparatively higher.

Evaluation of a granulated formula for the nerve root type and vertebral artery type of cervical spondylosis：a multicenter,single-blind,randomized,controlled,phase Ⅲ clinical trial

OBJECTIVE:To evaluate the effectiveness and safety of cervical spondylosis formula granules in reducing the symptoms of patients with the nerve root type and the vertebral artery type of cervical spondylosis.METHODS:This was a multicenter, single-blind,randomized, controlled trial.From April 2002 to November 2003, 499 patients were randomly assigned to either the treatment or the control group.The treatment group was orally administered granules prepared with a formula for cervical spondylosis, while the control group was given Jingfukang granules.The treatment course was 1 month for both groups.RESULTS:In patients with the nerve root type of cervical spondylosis, the total effect rate in the treatment group(87.21%) was significantly higher than that in the control group(80.70%, P < 0.01).After the treatment period in both groups, the treatment group had a significantly greater rate of resolution of pain, numbness of the upper limbs, muscle strength of the upper limbs, and fatigue than the control group(all P < 0.05).In patients with the vertebral artery type of cervical spondylosis, the total effect rate in the treatment group(82.07%) was similar to that in the control group(71.21%, P >0.05).After the treatment period in both groups,the treatment group had a significantly greater rate of resolution of weakness of the waist and knees than the control group(P < 0.05).CONCLUSION:The cervical spondylosis formula granules significantly improve numbness, muscle strength, and fatigue, and reduce pain in patients with the nerve root type of cervical spondylosis,and improve the weakness of the waist and knees in patients with the vertebral artery type of cervical spondylosis.

杵针治疗颈椎病随机对照试验分析

目的:通过分析文献探讨杵针治疗颈椎病的治疗现状。方法:通过搜索Pubmed、Cochane Library、Embase、Medline、中国知网、重庆维普、万方、中国生物医学数据库等8大数据库,检索关于杵针治疗颈椎病的随机对照试验(randomized control trials,RCT),对于符合纳入标准的RCT,以改良的JADAD评分分析其随机方法、盲法实施情况。结果:获得符合标准的RCT 10项,发现文献质量存在差异,杵针的选择穴位和工具较为集中,以大椎八阵和河车脑椎段为主,使用工具以4种工具综合使用为主。结论:单独或联合使用杵针具有治疗优势和特色,但文献的循证质量有待提高,应加强跨区交流、临床穴位配伍、对量效关系和基础机制的研究,以进一步明确杵针治疗颈椎病的效应机制。

不同远端取穴针刺治疗颈型颈椎病的临床随机对照试验

[目的]探讨不同远端取穴针刺治疗颈型颈椎病的临床疗效。[方法]选取2020年8月—2022年4月在天津市天津医院接受治疗的颈型颈椎病患者147例,按1∶1∶1比例随机分为治疗1组(局部联合后溪穴针刺),治疗2组(局部联合合谷穴针刺)和对照组(仅局部针刺)。3组患者均接受治疗2周治疗后随访1个月。比较两组患者简式麦吉尔疼痛问卷(MPQ)评分、颈椎功能障碍指数量表(NDI)评分、生活质量评价量表(SF-36)评分和总有效率。[结果]3组患者在治疗后和随访时的MPQ评分、NDI评分、SF-36评分均优于治疗前(P<0.05);治疗组1和治疗2组在治疗后和随访时的MPQ评分、NDI评分优于对照组,差异具有统计学意义(P<0.05);治疗1组在治疗后的MPQ评分、NDI评分优于治疗2组,差异具有统计学意义(P<0.05),随访时两组没有统计学差异(P>0.05);3组患者在治疗后和随访时的SF-36评分均无统计学差异(P>0.05);在总有效率方面,治疗1组优于对照组,差异具有统计学意义(P<0.05),治疗1组与治疗2组、治疗2组与对照组比较,差异无统计学意义(P>0.05)。[结论]局部取穴联合后溪穴远端取穴治疗颈型颈椎病的疗效最好,远期疗效可靠。

呼吸模式重建的功能锻炼结合隔姜灸治疗椎动脉型颈椎病的临床研究

目的观察呼吸模式重建的功能锻炼结合不同灸量的隔姜灸对椎动脉型颈椎病患者眩晕、颈肩痛、头痛等症状的影响,为临床治疗椎动脉型颈椎病提供安全有效的治疗方法。方法选取符合纳入标准的椎动脉型颈椎病患者120例,随机分为4组(n=30)。治疗1组行常规针刺+电针+推拿+呼吸模式重建功能锻炼结合隔姜灸3壮;治疗2组行常规针刺+电针+推拿+呼吸模式重建功能锻炼结合隔姜灸6壮;治疗3组行常规针刺+电针+推拿+呼吸模式重建功能锻炼结合隔姜灸9壮;对照组行常规针刺+电针+推拿+温和灸。记录患者治疗前后及治疗后第1个月、第3个月的颈性眩晕症状与功能量表评分(ESCV)及视觉模拟评分法(VAS)评分。结果治疗前4组患者ESCV、VAS评分组间比较差异均无统计学意义(P>0.05),治疗后1、2、3组ESCV评分均高于对照组(P<0.05),且治疗3组的ESCV评分最高(P<0.05);治疗1、2、3组VAS评分均低于对照组(P<0.05),且治疗3组的VAS评分明显低于其余三组(P<0.05)。结论呼吸模式重建的功能锻炼结合隔姜灸可明显改善患者眩晕、颈肩痛、头痛等症状,且灸量越大,疗效越好。该疗法安全无副作用,值得临床推广。

半夏白术天麻汤加减治疗椎动脉型颈椎病的Meta分析

目的:系统评价半夏白术天麻汤加减单独使用或与其他疗法联合应用治疗椎动脉型颈椎病(CSA)的临床疗效,为其临床应用提供循证学支持。方法:检索国内外主流文献数据库,搜索半夏白术天麻汤加减单独使用或与其他疗法联合应用(研究组)治疗CSA的随机对照试验(对照组为其他疗法),检索日期为建库至2022年11月22日。参照Cochrane手册5.1.0提供的标准评估文献质量及风险,应用EndNote X9.1软件进行文献管理,应用RevMan 5.4软件进行Meta分析。结果:最终纳入18篇文献,合计1822例患者(研究组936例,对照组886例)。Meta分析结果提示,研究组CSA患者的临床总有效率(OR=3.45,95%CI=2.66~4.48,Z=9.34,P<0.00001)、临床治愈率(OR=2.24,95%CI=1.83~2.73,Z=7.92,P<0.00001)高于对照组,差异均有统计学意义;研究组CSA患者椎-基底动脉血流速度、CSA眩晕症状和头痛症状的改善效果优于对照组,差异均有统计学意义(P<0.05);安全性分析结果显示,两组治疗方案均具有良好的安全性。结论:半夏白术天麻汤加减单独使用或与其他疗法联合应用可以治疗CSA,且可加快椎-基底动脉血流速度,促进血液循环,有效减轻患者的眩晕、头痛等临床症状,安全性良好。

针灸治疗失眠症随机对照试验的系统评价

目的 :评价针灸治疗失眠症的疗效。方法 :对针灸治疗失眠症的随机对照试验 (RCT)进行系统评价。统计方法数据用专用软件RevMan4 1版进行统计分析。结果 :6篇RCT共 5 85例患者满足纳入标准。 6篇均为低质量试验 ,均未使用盲法 ;Meta 分析的结果 ,针刺组和药物组比较 ,比值比 (OR)为 3 5 5 ,95 %的可信区间 [2 5 0 ,5 0 5 ],P <0 0 0 0 1。结论 :针灸治疗失眠症可能有效 ,但由于试验方法学质量较低 ,尚不能充分肯定 ,需高质量的试验进一步证实。

腹针治疗颈椎病临床随机对照研究

目的:比较腹针与传统针刺治疗颈椎病的临床疗效。方法:将62例颈型或神经根型颈椎病患者随机分为腹针组(观察组)32例,穴取中脘、关元等;传统针刺组(对照组)30例,穴取风池、颈夹脊等。以简化McGill疼痛询问量表(MPQ)及临床疗效为客观指标,比较两组第1次治疗后、疗程结束和3个月随访的疗效差异。结果:观察组有效率为100.0%,对照组为100.0%,两组比较,差异无显著性意义。两组治疗后和随访MPQ各项指标均较治疗前明显改善,观察组第1次治疗后与治疗前的疼痛分级指数(PRI)感觉分差值和第1次后、总疗程后和3个月随访与治疗前的PRI总分差值均较对照组明显改善(P<0.05)。结论:腹针能较好地缓解颈椎病患者的疼痛感觉,且有即时的缓解疼痛效果,但尚不能说其疗效优于传统针刺。

针灸治疗贝尔麻痹临床多中心随机对照试验研究

目的:证实针灸治疗贝尔麻痹的临床疗效。方法:4个中心共480例患者纳入研究,439例完成整个研究过程。所有病例随机分为对照组(基础组)和治疗组(基础加针灸组、针灸组)。基础组治疗用强的松、维生素B_1、维生素B_(12)及地巴唑,针灸组治疗用毫针刺加灸,基础加针灸组则二者结合。共治疗4周。采用症状体征、House-Brackmann分级量表、面部残疾指数(FDI)评分量表进行疗效评价。结果:4个中心完成情况良好,4个中心疗效差异无显著性,研究方案执行较好。3个组分组均衡,基线状况良好,可比性强(P>0.05);3个组的疗效差异有显著性,其中治疗组疗效优于对照组、针灸组疗效最好(P<0.05,P<0.01)。轻度面瘫和急性期面瘫疗效优于重度面瘫和非急性期面瘫(P<0.01)。比较治疗前后House-Brackmann量表分级和治疗前后面部残疾指数躯体功能评分(FDIP),治疗组疗效优于对照组(P<0.01)。结论:针灸治疗贝尔麻痹临床疗效肯定,其效果优于基础对照组和基础加针灸组。

针灸治疗颈椎病远期疗效的系统评价

目的评价针灸治疗颈椎病的远期疗效。方法收集针灸治疗颈椎病远期疗效的随机对照试验文献,对符合纳入标准的文献按改良后的Jadad计分表评价其质量,对纳入的试验作系统评价,同时按远期疗效指标的不同进行分层分析。结果符合纳入标准的文献共11篇,研究对象1 723例患者。Meta分析结果显示,针灸治疗组与对照组远期疗效痊愈率相比,OR为3.42,95%CI〔2.64,4.43〕,治疗组痊愈率优于对照组,差异有统计学意义(P<0.000 01)。针灸治疗组对比对照组复发率,OR为0.45,95%CI〔0.23,0.91〕,治疗组远期疗效优于对照组,差别有统计学意义(P=0.03);其中干预措施仅为单纯针刺的P=0.02,I2=67%,采用随机效应模型检验,其合并OR为0.52,95%CI〔0.19,1.44〕,差别无统计学意义(P=0.21)。结论针灸治疗颈椎病远期疗效优于对照组,但需要高质量、大样本、更规范疗效指标的研究进一步证明。

针挑治疗颈椎病的随机对照研究

目的:运用随机对照临床研究方法,对针挑治疗颈椎病进行疗效评价。方法:将158例患者随机分为针挑治疗组(针挑组)56例、常规针刺对照组(针刺组)55例与局麻对照组(局麻组)47例。取穴均为颈百劳、大椎、肩井等,分别采用针挑法、常规针刺法及局部麻醉法治疗。采用简化McGill疼痛询问量表等量化计分,结合临床症状、体征进行疗效分析。结果:针挑组痊愈率为57.1%,优于针刺组的23.6%与局麻组的14.9%(均P<0.01),针挑治疗基本无不良反应。结论:针挑疗法对于颈椎病是一种高效、安全的疗法。

手法治疗椎动脉型颈椎病临床随机对照试验的系统评价

目的:评价手法治疗椎动脉型颈椎病的安全性、有效性,分析目前临床治疗现状。方法:检索PubMed、OVID、Cochrane图书馆、CBM、CNKI、VIP等数据库以及手工检索,共收集手法治疗椎动脉型颈椎病的文献265篇,中文文献251篇,英文文献14篇,其中5篇符合纳入研究标准,全部为中文文献;Cochrane系统评价手册进行质量评价,并对5篇文献采用RevMan 4.2进行Meta分析。结果:纳入的5篇文献共736例患者。5篇文献的治愈率汇总合并OR为2.93,95%CI为[2.10,4.08];有效率汇总合并OR为3.99,95%CI为[2.47,6.44];手法对椎动脉型颈椎病的治愈率、有效率均明显优于其他疗法(除手法之外的治疗方法,如牵引、药物等)(P<0.01)。结论:目前所纳入研究结果显示手法治疗椎动脉型颈椎病安全、有效,手法对椎动脉型颈椎病的治愈率、有效率明显优于其他疗法;但由于纳入文献的数量有限且质量不是很高,结论尚不确定,因此需要多中心的临床随机对照且长时间随访的试验,进一步验证。

针刀联合端提旋转手法治疗神经根型颈椎病的病例对照研究

目的 :比较针刀联合旋提手法与单纯旋提手法治疗神经根型颈椎病患者的临床疗效,探讨针刀治疗神经根型颈椎病的作用机制,为临床治疗提供依据。方法:2013年11月至2015年6月,将符合纳入标准的神经根型颈椎病80例患者随机分为治疗组和对照组,对照组39例,单纯采用旋提手法,每日1次,2周为1个疗程,连续治疗1个疗程;治疗组41例,采用针刀联合旋提手法治疗,1周1次,针刀治疗后观察30 min,如患者无特殊不适则开始进行手法治疗,手法同对照组,每日1次,2周为1个疗程,连续治疗1个疗程,观察两组治疗前后症状、体征积分变化及临床综合疗效。结果:两组患者治疗后,各症状体征积分均较治疗前明显下降(P<0.05),且治疗组优于对照组(P<0.05)。治疗组痊愈19例,显效16例,有效5例,无效1例;对照组痊愈10例,显效10例,有效16例,无效3例;两组比较差异有统计学意义(P<0.01),治疗组优于对照组。结论:针刀联合旋提手法治疗神经根型颈椎病优于单纯手法治疗,可改善局部血液循环,降低局部致痛物质的含量,增加体内生成的抗痛物质,疏通经络,可使机体在新的基础上达到新的静态和动态平衡。

时相性辨证分期推拿疗法治疗气滞血瘀型神经根型颈椎病临床研究

目的:评价时相性辨证分期推拿疗法治疗气滞血瘀型神经根型颈椎病的临床疗效。方法:将80例来自天津中医药大学第一附属医院推拿科门诊的气滞血瘀型神经根型颈椎病(CSR)患者随机分为治疗组和对照组各40例。治疗组采用时相性辨证分期推拿疗法,对照组采用传统推拿法。以25 d为观察周期,分别于治疗前、治疗第7天、第15天以及治疗第25天对患者进行颈部功能障碍指数(NDI)、疼痛视觉模拟标尺评估(VAS)观察,并采集入组、出组患者的神经根周围脂肪CT值进行比较。结果:试验组总有效率为100%,愈显率为97.44%;对照组总有效率为97.30%,愈显率为72.97%,试验组优于对照组(P<0.01)。两组患者治疗后VAS、NDI评分,神经根周围脂肪CT值均较治疗前明显下降,且试验组优于对照组(P<0.05)。结论:与传统推拿疗法相比较,时相性辨证分期推拿疗法可有效改善气滞血瘀型CSR患者的临床症状,降低神经根水肿程度。

颈椎定点引伸手法治疗神经根型颈椎病的随机对照研究

背景:神经根型颈椎病是临床常见病、多发病,颈椎定点引伸手法是治疗神经根型颈椎病的方法之一。目的:评价颈椎定点引伸手法治疗神经根型颈椎病的临床疗效。设计、场所、对象和干预措施:采用前瞻性随机对照设计,84例神经根型颈椎病患者均为解放军总医院康复医学科门诊患者,随机分为治疗组和对照组,每组42例。治疗组采用颈椎定点引伸手法治疗,隔日1次,共7次;对照组单纯使用颈椎电脑牵引治疗,1次/d,每次30min,治疗14d。主要结局指标:采用视觉模拟量表(visual analogue scale,VAS)评估疼痛强度,应用红外热成像仪采集健肢与患肢皮肤温度,并计算健、患侧上肢温度差值。结果:治疗中脱落5例,其中治疗组1例,对照组4例。治疗组治疗后VAS评分和健、患侧上肢皮肤温度差值低于治疗前(t=28.652,P<0.01;t=64.214,P<0.01);对照组治疗后VAS评分和健、患侧上肢皮肤温度差值亦低于治疗前(t=14.484,P<0.05;t=84.425,P<0.05);治疗组VAS评分和上肢温度差值治疗前后的差异较对照组明显(t=7.494,P<0.01;t=5.321,P<0.01)。结论:颈椎定点引伸手法治疗神经根型颈椎病疗效优于颈椎牵引法,主要表现为缓解患者疼痛和减轻神经根压迫等。

针刺治疗急性缺血性脑卒中随机对照观察

目的观察针刺改善急性缺血性脑卒中患者的日常生活能力、降低患者的残障/死亡率的作用。方法将40例急性缺血性脑卒中患者随机分为针刺组和非针刺组各20例。针刺组采用针刺(每周5次,共3～4周)加常规治疗;非针刺组采用常规治疗。结果治疗期末神经功能缺损评分针刺组略优于对照组,但差异无显著性意义(P>0.05);3个月、6个月随访时针刺组残障/死亡率略低于对照组,但差异无显著性意义(P>0.05)。结论早期针刺治疗是安全和可行的。