Effect of Nursing Intervention Based on Caprini Risk Assessment Scale for Venous Thromboembolism in Perioperative Patients with Liver Cancer

Objective:To explore the effect of nursing intervention based on Caprini risk assessment scale for venous thromboembolism(VTE)in perioperative patients with liver cancer.Methods:A total of 128 hepatocellular cancer(HCC)patients who were hospitalized in our department from January 2021 to March 2022 and met the research criteria were selected.According to odd and even numbers in the order of inclusion,64 cases were divided into two groups:a control group and an observation group.The control group received routine nursing intervention during perioperative period,while the observation group received nursing intervention based on Caprini risk assessment scale for VTE.The incidence of VTE and complications were compared between the two groups.Results:The incidence of VTE and postoperative complications in the observation group were lower than those in the control group(P<0.05).Conclusion:Nursing intervention based on Caprini risk assessment scale for VTE can reduce the incidence of perioperative deep vein thrombosis and complications in patients with liver cancer;thus,it is worthy of clinical application.

Cervical cancer: Epidemiology, risk factors and screening

Cervical cancer is one of the leading causes of cancer death among females worldwide and its behavior epidemiologically likes a venereal disease of low infectiousness. Early age at first intercourse and multiple sexual partners have been shown to exert strong effects on risk. The wide differences in the incidence among different countries also influenced by the introduction of screening. Although the general picture remains one of decreasing incidence and mortality, there are signs of an increasing cervical cancer risk probably due to changes in sexual behavior. Smoking and human papillomavirus(HPV) 16/18 are currently important issues in a concept of multifactorial, stepwise carcinogenesis at the cervix uteri. Therefore, society-based preventive and control measures, screening activities and HPV vaccination are recommended. Cervical cancer screening methods have evolved from cell morphology observation to molecular testing. High-risk HPV genotyping and liquid-based cytology are common methods which have been widely recommended and used worldwide. In future, accurate,cheap, fast and easy-to-use methods would be more popular. Artificial intelligence also shows to be promising in cervical cancer screening by integrating image recognition with big data technology. Meanwhile, China has achieved numerous breakthroughs in cervical cancer prevention and control which could be a great demonstration for other developing and resource-limited areas. In conclusion, although cervical cancer threatens female health, it could be the first cancer that would be eliminated by human beings with comprehensive preventive and control strategy.

The Role of the PNI and NLR in Nutritional Risk Screening and Assessment of Gastric Cancer Patients

Background The use of nutritional risk screening and assessment is becoming increasingly common in cancer patients.The Nutritional Risk Screening 2002(NRS 2002)is a nutritional risk screening programe with good utility.The patient generated-subjective global assessment(PG-SGA)is a method used to assess the nutritional status of cancer patients.The prognostic nutritional index(PNI)and neutrophil to lymphocyte ratio(NLR)are considered to be predictors of the prognosis following treatment for patients with a variety of cancers.However,the relationship between the PNI and NLR in the nutritional screening and assessment in patients with gastric cancer is unknown.Methods A retrospective analysis was performed on 378 patients with gastric cancer who underwent surgery at the First Affiliated Hospital of Guangxi Medical University from August 2019 to December 2020.NRS 2002 and PG-SGA were performed within 24 hours of admission,and indicators such as the serum albumin level,body mass index(BMI),PNI and NLR were measured.Results In the grouping based on the NRS2002,patients in the positive group(NRS 2002≥3)had a higher platelet value,a higher median NLR,and a lower PNI than those in the negative group(NRS 2002<3)(295.50±118.49×10^(9)/L vs.269.36±93.52×10^(9)/L,2.38 vs.1.77,42.36±5.96 vs.46.64±4.29).Based on the PG-SGA grouping,the serum albumin level and lymphocyte count were highest in the mild group(PG-SGA:score 2-3),(36.94±3.51 g/L and 1.91±0.7610^(9)/L)and lowest within the severe group(PG SGA score≥9)(34.09±4.18 g/L and 1.51±0.6410^(9)/L).The BMI was highest in the mild group(23.35±3.00 kg/m^(2))and lowest in the severe group(20.63±2.97 kg/m^(2)),and the PNI was also highest in the mild group(46.50±5.17)and lowest in the severe group(41.64±5.53).However,the NLR was lowest in the mild group(median 1.91)and highest in the severe group(median 2.44).Conclusion The PNI and NLR in gastric cancer patients are closely related to the results of the nutritional risk screening and assessment,suggesting that they may be useful to guide the nutritional interventions for gastric cancer patients.

Assessment of Knowledge of Cervical Cancer and Pap Smear Screening in Makurdi Metropolis

Knowledge of cervical cancer and Pap smear screening in a sample population in Makurdi metropolis was assessed using a survey design. Five hundred and seventy-four （574） participants aged 18-60 years, who were accidentally/conveniently sampled in the town, took part in the study. Of this number, 48.3% （N = 277） were males, and 51.7% （N = 297） were females and from diverse occupations. Data were collected using a standardized questionnaire, the knowledge of cervical cancer and Pap Smear Screening Scale （KCPS） with ten items. Results reveal that participants have limited knowledge on cervical cancer and Pap Smear Screening with 35.3% （N = 203） having knowledge, while 64.7% （N = 371 ） having limited knowledge. No statistical significant difference in the knowledge of cervical cancer and Pap Smear Screening between older and younger participants t （553） = -1.69; P 〉 0.05, Single and Married participants t （562） = -0.97; P 〉 0.05, low and high levels of education t （564） = -1.83; P 〉 0.05 was found. Surprisingly, males （mean = 33.55） significantly had more knowledge of cervical cancer and Pap Smear Screening than females （mean = 32.26） t （572） = 2.03; P 〈 0.05 and other participants had better knowledge than health workers t （572） = -2.43; P 〈 0.05. Enlightenment campaigns, Magazines and News papers, Television, Radio, Friends and Schools were some of the sources participants acquired knowledge of cervical cancer and Pap Smear Screening. It is obvious that knowledge of cervical cancer and Pap Smear Screening is limited among the population in Makurdi metropolis, therefore a need to intensify enlightenments and awareness campaigns targeted at all groups of people is imperative.

Clinical application of DNA ploidy to cervical cancer screening: A review

Screening for cervical cancer with DNA ploidy assessment by automated quantitative image cytometry has spread throughout China over the past decade and now an estimated 1 million tests per year are done there. Compared to conventional liquid based cytology, DNA ploidy has competitive accuracy with much higher throughput per technician. DNA ploidy has the enormous advantage that it is an objective technology that can be taught in typically 2 or 3 wk, unlike qualitative cytology, and so it can enable screening in places that lack sufficient qualified cytotechnologists and cytopathologists for conventional cytology. Most papers on experience with application of the technology to cervical cancer screening over the past decade were published in the Chinese language. This review aims to provide a consistent framework for analysis of screening data and to summarize some of the work published from 2005 to the end of 2013. Of particular interest are a few studies comparing DNA ploidy with testing for high risk human papilloma virus(hrH PV) which suggest that DNA ploidy is at least equivalent, easier and less expensive than hrH PV testing. There may also be patient management benefits to combining hr HPV testing with DNA ploidy. Some knowledge gaps are identified and some suggestions are made for future research directions.

Assessing the Effectiveness of a Cervical Cancer Screening Program in a Hospital-based Study

This study compared HPV testing and liquid-based cytology （LCT） as performance indicators for cervical cancer screening in a hospital-based study. A total of 61,193 outpatients were screened initially by LCT. Samples with screening results showing atypical squamous cells of undetermined significance （ASC-US） or worse were referred for colposcopy, and some samples were tested for high-risk HPV types with the Hybrid Capture II system （HC II）. Data on LCT （n=61,193） and HC II （n=1056） results were analysed. Overall test positivity for LCT was 2.53% using an ASC-US threshold, 3.11% using a low-grade squamous intraepithelial lesion （LSIL） threshold, and 0.67% using a high-grade squamous intraepithelial lesion （HSIL） threshold. A total of 1839 women （84% of the 3893 patients with abnormal cytology） underwent colposcopy-directed biopsy. HPV was positive in 80.3% of women with cervical intraepithelial neoplasia 1 （CIN1）, 88.3% of those with CIN2, 79.2% of women with CIN3 and 50% （2 of 4） of women with invasive cancer. There was a significant increase in the detection of CIN2 or worse with adjunct HPV testing of women with ASC-US and LSIL However, there were detection of CIN2＋ cases no differences in the with adjunct HPV testing of women with HSlI.. The results indicate that HPV testing for HSlL triage should not be recommended in cervical cancer screening.

Cervical cancer screening among female undergraduates and staff in the Niger delta region of Nigeria

A significant decrease in the incidence of cervical cancer and mortality is expected when all eligible women have access to regular Screening tests. Factors that can influence participation rate include: acceptability, accessibility, screening interval, promotion of screening among others. This study is aimed at the assessment of the risk factors for cervical cancer, the knowledge and level of utilization of cervical cancer screening among female staff and female undergraduates of Niger Delta University. A standard questionnaire was used for data collection. The questions were made to capture the objectives of the study. 182 (50.6%) were aware of cervical cancer screening, 22 (12.1%) of the respondents have had at least one pap test in the past, the commonest reasons for uptake of screening were;When it is free or subsidized 6 (27.3%), as part of a general screening program 6 (27.3%), Doctor’s request 4 (18.2%) and self-conviction 4 (18.2%). Many 98 (41.4%) of the respondents, considered themselves healthy and did not see any reason to subject themselves to any form of cervical cancer screening. The reasons for uptake and non uptake of cervical cancer screening are statistically significant between the students and staff (x2 = 18.175, p = 0.001;x2 = 11.31, p = 0.046). The mean age for the initiation of penetrative sex among the respondents was 15.4 ± 2.7, 226 (71.1%) had more than one sexual partner and 184 (51.0%) had been treated for sexually transmitted infections in the past. The study shows that awareness of cervical cancer screening and Uptake was low amongst the respondents, this is despite the fact that a large proportion of the respondents had risk factors for cervical cancer.

甲基化PAX1在宫颈癌筛查和预后评估中的临床应用

目的:探究甲基化PAX1在宫颈癌筛查和预后评估中的临床应用。方法:选取2021年1月~2021年12月在蚌埠医学院第一附属医院接受治疗的150例收集宫颈脱落细胞患者的宫颈脱落细胞,研究采用了多种检测技术,包括PAX1基因、甲基化、薄层细胞学、高危型人乳头瘤病毒(HR-HPV)和HPV16/18检测,以阳性患者进行阴道镜下活检病理诊断为金标准,比较宫颈脱落细胞中不同检测方法学。结果:PAX1基因甲基化灵敏度、特异度分别为81.3%和96.6%,四种检测比较中PAX1具有最高特异度(96.63%),细胞学与HR-HPV检测特异度在17%~70%。细胞学(ASCUS+)的灵敏度为94.7%,明显高于PAX1基因甲基化检测,差异有统计学意义(P<0.05),ASCUS+的特异度为18.0%显著低于PAX1基因甲基化检测,差异有统计学意义(P<0.001)。结论:将细胞学和PAX1基因甲基化技术相结合,能够更好地预防宫颈癌,并且能够减轻年轻患者的焦虑。

肿瘤患者跌倒风险感知量表的编制及信效度检验

目的编制肿瘤患者跌倒风险感知量表并检验信效度,为肿瘤患者跌倒防范提供自评工具。方法通过文献回顾、专家函询、小组讨论等方式构建量表,选取407例肿瘤患者进行调查,检验量表信效度。结果肿瘤患者跌倒风险感知量表包括跌倒认知易感知性(5个条目)、生理状况易感知性(12个条目)、个人活动易感知性(5个条目)、环境因素易感知性(5个条目)、跌倒严重性感知(3个条目)5个维度共30个条目。探索性因子分析提取5个公因子,累计方差贡献率66.746%。量表总的Cronbach′sα系数为0.926,折半信度为0.672,各维度Cronbach′sα系数为0.914~0.970,折半信度为0.877~0.963。量表水平的内容效度指数为0.867,条目水平的内容效度指数为0.813~1.000。验证性因子分析结果显示,χ^(2)/df=1.845,RMSEA=0.059,GFI=0.840,CFI=0.971,NFI=0.939,AGFI=0.811,模型适配良好;AVE平方根均显著大于相关系数,各维度之间有显著相关性(均P<0.05)。结论肿瘤患者跌倒风险感知量表信效度良好,可用于肿瘤患者跌倒风险感知的评估。

肺癌化疗患者味觉改变与其营养状况及癌因性疲乏的相关性研究

目的探索肺癌化疗患者味觉改变与其营养状况及癌因性疲乏的相关性。方法回顾性分析苏州市中医医院2021年2月至2024年2月期间收集的137例肺癌化疗患者,应用化疗相关味觉改变量表(CiTAS)、营养风险筛查2002(NRS 2002)、癌因性疲乏(CFS)状态进行评估,经Pearson法和线性回归分析CiTAS评分、NRS 2002评分、CFS评分相关性,同时,经中介效应分析三者的关系。结果肺癌化疗患者的基本味觉改变评分(15.52±2.52)分、味觉异常和味幻觉(9.12±2.63)分、进食困扰(20.15±2.35)分、整体味觉改变(12.35±2.89)分、CiTAS总分(57.13±7.78)分,NRS 2002评分(4.89±2.22)分,躯体疲乏(24.86±2.84)分、情感疲乏(12.36±2.39)分、认知疲乏(11.78±2.55)分、CFS总分(49.01±6.60)分。经Pearson法分析,Ci-TAS总分与NRS 2002评分,躯体疲乏、情感疲乏、认知疲乏、CFS总分呈正相关;经线性回归分析,NRS 2002评分、CiTAS总分会影响CFS总分;经中介效应分析,NRS 2002评分(β=0.469,P<0.001)与CiTAS总分(β=1.105,P<0.001)均可以显著正向预测CFS总分;CiTAS总分在NRS 2002评分、CFS总分影响中起到部分中介作用,中介效应占总效应比例的21.17%。结论肺癌化疗患者味觉改变症状明显,处于中重度水平,且会直接影响营养状况及癌因性疲乏,味觉改变越严重,营养状态、癌因性疲乏越严重,呈正相关,对此需积极开展营养治疗,调整食物口味,适应患者味觉需求,以保证足够营养摄入,改善身心健康状态。

儿童肿瘤患者营养筛查量表的应用和筛选

营养不良降低儿童肿瘤患者的生命质量,增加其术后医院感染的风险。针对这一问题,尽早对儿童肿瘤患者进行营养筛查,并对存有营养不良风险的患儿采取干预措施,对预防营养不良及相关并发症极为重要。在我国,儿童肿瘤患者营养不良率相对较高,而肿瘤的类型、分期及治疗方案的个体差异性等多重因素,增加了评估儿童肿瘤患者是否营养不良的复杂性。目前,多数研究采用国外的营养风险评估量表,不同量表之间的结果难以统一和比较。因此,制订一套针对性强、适用于我国国情的临床营养筛查量表成为迫切需求。本文通过对比国内外当前儿童营养筛查量表的筛查目标、适用人群、评估内容、评分标准、实际应用、使用限制及效果评估方面的异同,归纳总结各自的优缺点,提出对现有量表的改进建议及制订适用于我国儿童肿瘤患者营养筛查量表的意见,旨在推进我国儿童肿瘤患者营养筛查量表的制订和应用。

健康管理防治围妊娠期宫颈高危人乳头瘤病毒感染的应用价值

目的:探讨围妊娠期宫颈高危人乳头瘤病毒(HPV)感染应用健康管理的防治价值。方法:选取2021年1月—2022年1月攀枝花市中心医院收治的围妊娠期宫颈高危HPV感染患者80例作为研究对象,根据随机数表法分为常规管理组(常规管理)与健康管理组(健康管理),各40例。比较两组妊娠意愿、高危HPV感染转阴率与病毒负荷量相对光单位(RLU)/临床阈值(CO)、临床疗效、HPV感染知信行评分。结果:健康管理组妊娠意愿率高于常规管理组,差异有统计学意义(P=0.001);干预1年后,健康管理组高危HPV感染转阴率高于常规管理组,病毒负荷量RLU/CO低于常规管理组,差异有统计学意义(P<0.001);健康管理组总有效率高于常规管理组,差异有统计学意义(P=0.034);干预后,两组知识、态度、行为评分高于干预前,健康管理组高于常规管理组,差异有统计学意义(P<0.05)。结论:健康管理在围妊娠期宫颈高危HPV感染患者中的防治效果较好,可提高患者的妊娠意愿、高危HPV感染转阴率,促进病毒负荷量RLU/CO下降和知信行评分提高。

宫颈癌筛查妇女高危型人乳头瘤病毒感染现状及影响因素研究:基于成都市45万人群

背景宫颈癌是女性常见恶性肿瘤之一,其病因明确,通过规范筛查可以有效降低宫颈癌发病率。人乳头瘤病毒(HPV)检测是WHO推荐的首选宫颈癌筛查方法,了解成都市高危型人乳头瘤病毒(hrHPV)感染状况,对优化成都市宫颈癌筛查方案具有重要意义。目的分析成都市35~64岁参加宫颈癌筛查人群的hrHPV感染现状和宫颈病变患者的hrHPV亚型感染分布情况,探讨hrHPV阳性检出率的相关影响因素。方法从“成都市育龄妇女生殖健康数据库”收集2023年参加成都市免费宫颈癌筛查的459433例个案数据,分析不同hrHPV基因型感染总体分布情况以及宫颈病变患者的hrHPV亚型感染分布情况,比较不同特征人群hrHPV感染情况,并构建多水平Logistic回归模型分析hrHPV检出阳性情况的相关因素。结果459433例中,hrHPV阳性检出率为11.65%(53509/459433),hrHPV感染随年龄的增长呈上升趋势(χ_(趋势)^(2)=1501.082,P<0.001)。82.39%(131/159)的宫颈癌患者感染HPV 16或18亚型,以单纯感染HPV 16亚型为主(52.20%,83/159)。多水平Logistic回归分析结果显示,年龄、文化程度、婚姻状况、绝经状态、避孕方式、妊娠次数、分娩次数为hrHPV阳性检出情况的影响因素(P<0.05)。结论成都市女性hrHPV阳性检出率略低于全国平均水平。在筛查过程中,要重视健康教育与随访工作,特别是对HPV 16或18亚型阳性者的后续随访工作。开展宫颈癌筛查宣传工作时应特别关注年长者、文化程度较低者、未婚或离异/丧偶者、已绝经者、未避孕或采用避孕套外的其他避孕方式者、妊娠或分娩2次以上者等重点人群,加强宫颈癌防治核心知识、生殖健康知识等的宣传,提高妇女健康素养。

癌症儿童多症状测评工具的范围综述

目的 比较国内外用于癌症患儿的多症状测评工具,为癌症患儿症状管理提供参考。方法 计算机检索PubMed、Web of Science、EMbase、中国期刊全文数据库、中国生物医学文献数据库、万方数据库,查找用于测评癌症患儿多症状评估的工具,检索时限为从建库至2022年9月。提取各工具的条目数、信效度、评分方法、适用对象等信息,对纳入工具进行描述。结果 最终纳入9个持续性评估工具,共28篇全文文献,其中9篇关于评估工具的开发、19篇关于评估工具的运用。结论 目前癌症患儿的多症状测评工具良莠不齐,有必要开发针对不同群体的多症状群测评工具,以保证动态追踪患儿的症状变化,拟订干预措施,促进癌症患儿的症状管理。

门诊宫颈防癌筛查女性HPV感染情况及HR-HPV持续性感染的Logistic回归分析

目的探讨门诊宫颈防癌筛查女性人乳头瘤病毒(HPV)感染情况及高危型人乳头瘤病毒(HR-HPV)持续性感染的危险因素。方法选取2021年1月至2022年12月在浙江省东阳市妇幼保健院接受宫颈防癌筛查的340例女性作为研究对象,根据是否发生HPV感染分为HPV感染组(n=72)和HPV未感染组(n=268)。分析HPV感染情况及HR-HPV持续性感染的危险因素。结果HPV感染72例(21.18%),单一HPV亚型感染55例(76.38%),多重感染17例(23.61%)。72例HPV感染患者中持续性感染17例(23.61%),其中HR-HPV持续性感染11例(64.71%)。年龄≥35岁、妊娠次数>2次、初次性交年龄<25岁、性生活频率>5次/月、有宫颈阴道炎症、性伴侣人数>2名、避孕方式为口服避孕药、同房后无卫生习惯的女性HR-HPV持续性感染率更高(P<0.05)。年龄≥35岁、妊娠次数>2次、有宫颈阴道炎症、避孕方式为口服避孕药是宫颈防癌筛查女性HR-HPV持续性感染的危险因素(P<0.05)。结论在女性宫颈防癌筛查者中HPV感染占比较高,年龄越大、妊娠次数越多、有宫颈阴道炎症且避孕方式为口服避孕药的女性HR-HPV持续性感染风险越高。

TCT检查联合高危型HPV检测在宫颈癌筛查中的应用效果

目的:探究宫颈液基细胞学(TCT)检查联合高危型人乳头瘤病毒(HR-HPV)检测在宫颈癌筛查中的应用效果。方法:收集2022年1月-2023年5月本院行宫颈癌筛查的3500例临床资料,以病理学诊断为金标准,采用受试者工作特征(ROC)曲线分析TCT、HR-HPV检查及两者联合对宫颈癌的筛查效能。结果:3500例中病理诊断宫颈癌33例,余112例为CINⅡ+Ⅲ、267例为CINⅠ、3088例为宫颈炎。ROC曲线分析,TCT筛查宫颈癌的曲线下面积(AUC)为0.741,敏感度48.5%、特异度99.7%;HR-HPV检测筛查宫颈癌的AUC为0.769,敏感度54.6%、特异度99.3%;TCT联合HR-HPV筛查(即其中任意一项为阳性即可诊断为宫颈癌阳性)宫颈癌的AUC为0.980,敏感度97.0%、特异度99.1%。结论:TCT联合HR-HPV检测具备较高诊断效能,可提升宫颈癌筛查的敏感度,用于宫颈癌及癌前病变的临床筛查有较高临床价值。

白带常规与高危型HPV检测在两癌筛查中的应用价值

目的分析在两癌筛查中应用白带常规与高危型HPV检测的效果。方法收录样本的时间为2022年10月至2023年10月,样本对象为200例接受两癌筛查的妇女,均为其提供白带常规与高危型HPV检测,分析两种措施的筛查效果。结果经宫颈病理显示为阳性患者的例数为40例,阴性例数为160例,经高危型HPV与白带常规的筛查结果显示,阳性例数为97例,阴性例数为103例,灵敏度为75.00%,特异度为58.12%,准确率为61.50%。经白带常规检查提示:清洁度正常患者的检出例数为36例,占比为18.00%;清洁度异常患者的检出例数为164例,占比为82.00%,清洁度异常患者的检出率高于清洁度正常患者的检出率(P<0.05);清洁度正常患者的病菌感染检出例数为6例,占比为16.67%;清洁度异常患者的病菌感染的检出例数为97例,占比为59.15%清洁度异常患者的病菌感染检出率高于清洁度正常患者的病菌感染检出率(P<0.05)。结论在进行两癌筛查期间,应用高危型HPV检测的灵敏度相对较高,而白带常规检查可以有效检验受检者是否存在病原菌感染的情况。通过将其联合应用进行干预,可以为临床对两癌疾病的早期诊疗提供依据。

HPV检测及TCT在宫颈癌筛查中联合应用的效果

目的分析高危型人乳头瘤病毒(HR-HPV)、液基薄层细胞学检查(TCT)及联合检查在宫颈癌筛查中的应用效果。方法选取2022年5月至2023年5月该院收治进行宫颈癌筛查150例患者为研究对象,上述所有研究样本均进行HR-HPV、TCT与联合检测,以组织病理学检查结果为诊断金标准。评价观察单独两组检测方法诊断结果以及3组检查方法诊断效能变化差异。结果组织病理学检查结果诊断提醒,阳性者77例(CINⅠ有35例,CINⅡ有21例,CINⅢ或原位癌有15例,宫颈浸润癌有6例),阴性者73例,HR-HPV检查法检查结果发现阳性者有80例,阴性者70例,对于分型检测结果差异有统计学意义(P<0.05);TCT检查结果发现,阳性者有71例,阴性者有79例,分型检测结果差异有统计学意义(P<0.05);3组诊断方法诊断结果差异性分析发现,联合检查方法诊断效能显著较高,差异有统计学意义(P<0.05)。结论在宫颈癌疾病筛查中,采取HR-HPV与TCT检查方法,能够进一步提升疾病诊断准确率,可为患者后续诊治提供良好的诊断依据,临床可进一步推广运用。

风险评估策略基础下行手术室护理干预在宫颈癌根治术中的应用及对患者心理与社会适应能力、风险症状的影响

目的:探讨风险评估策略基础下行手术室护理干预在宫颈癌根治术中的应用及对患者心理与社会适应能力、风险症状的影响。方法:选取2020年1月至2024年1月期间在本院行根治性切除术治疗的宫颈癌患者132例,随机分为两组,对照组采用常规护理干预、观察组采用风险评估策略基础下行手术室护理干预,比较两组康复指标、风险症状发生率、心理社会适应能力评分。结果:观察组肛门首次排气时间、留置引流管时间、住院时间以及风险症状发生率均低于对照组(P<0.05);干预后,观察组PAIS-SR总评分以及各维度评分均高于对照组(P<0.05);观察组膀胱功能恢复率、护理总满意率高于对照组(P<0.05)。结论:风险评估策略基础下行手术室护理干预能加速宫颈癌根治术患者康复进程,降低风险症状发生率,改善患者心理与社会适应能力,护理满意度高。

TCT联合HPV检测应用于妇女早期宫颈癌筛查作用分析

目的分析TCT联合HPV检测应用于35~65岁妇女早期宫颈癌筛查作用。方法选取本院筛查早期宫颈癌的5000例妇女为研究对象,所有检查妇女均接受液基薄层细胞检测(TCT)与HPV(高危型人乳头状瘤病毒DNA检查),将活检病理学结果作为“金标准”,统计不同检测方式的筛查效果。结果TCT联合HPV检测在早期宫颈癌中检出率显著高于两项方法单独应用检出率,差异有统计学意义(P<0.05)。TCT在SCC、HSIL以及LSIL等方面阳性检出率明显低于正常以及炎症女性HPV阳性检出率,差异有统计学意义(P<0.05)。与“金标准”检查结果相比,TCT联合HPV检测在CINⅢ级以上病变检出率非常高,筛查作用明显,差异有统计学意义(P<0.05)。结论在育龄妇女早期宫颈癌筛查过程中应用TCT联合HPV检测对病变组织检出率敏感性较高,可有效提高筛查检出率,减少漏诊及误诊情况。