Experiences with the Use of Vaginal Dilator by Cervical Cancer Women Who Received Pelvic Radiotherapy at Cancer Diseases Hospital, Lusaka Zambia

Background: Cancer of the cervix is the commonest cancer in women seen at Cancer Diseases Hospital in Zambia and Pelvic Radiotherapy is the main treatment modality used on cervical cancer patients. Radiotherapy to the pelvis has a potential to causes vaginal stenosis but the stenosis can be prevented by regular sexual intercourse or use of vaginal dilators as recommended by cancer organizations. Despite the well-established benefits of vaginal dilators, there was reluctance by women to adopt this practice as seen by the number of survivors with vaginal stenosis at Cancer Diseases Hospital. The objective of this study was to explore experiences with the use of vaginal dilators by cervical cancer women who received Pelvic Radiotherapy. Methodology: A descriptive phenomenological design was used to explore experiences with the use of vaginal dilators by cervical cancer women. The study was conducted at Cancer Diseases Hospital in Lusaka District of Zambia. Participants were identified and purposefully sampled during the follow up clinics, they were then followed for interviews into their homes in Lusaka and data saturation was attained after interviewing 22 participants. Data were analyzed using thematic analysis. Results: Five themes from the study emerged on how women with cervical cancer experienced the use of vaginal dilator;such as uncomfortable dilators, pity for the husband, changed lifestyle, embarrassment and fear. Conclusion: It was acknowledged that the use of vaginal dilator was associated with negative experiences such as uncomfortable dilators, pity for the husband, changed lifestyle, fear and embarrassment. Therefore, this study recommends that Health care providers from CDH and other health institutions should give appropriate information to patients concerning the use of vaginal dilators and the Ministry of Health to provide vaginal dilators instead of 50 milliliter syringes currently in use.

Changing Trends in Rate of Cervical Dilation in First Stage of Labor: Prospective Longitudinal Study

Introduction: Knowledge of change in the duration of stages of labour would be an essential step to reduce the increasing rates of cesarean section reported worldwide. Objective: To study the rate of cervical dilation in the 1st stage of labour in spontaneous and induced labour and in primigravida and multigravida with singleton pregnancy. Methods: A prospective observational study conducted at a multispeciality hospital was carried out for a period of 3 years from Jan 2017 to Dec 2019. A total of 640 patients who were admitted with spontaneous and induced labour having singleton pregnancy with cephalic presentation and intact membranes after 34 weeks who delivered vaginally were included for analysis. Progression of labor in the 1st stage of labour was measured by the rate of cervical dilation as noted by serial per vaginal examination and findings were plotted in partograph. Result: The difference between mean rate of cervical dilation in the study group is statistically significant between 4 - 6 cm and 6 - 10 cm (P < 0.0001). When primigravida & multigravida patients were compared for the cervical dilation rate, statistically significant difference was seen between 4 - 6 cm but not in 6 - 10 cm. Average rate of cervical dilatation was 3.44 (Standard Deviation (SD) = 1.84) in spontaneous labor while average rate of cervical dilatation was 2.69 (SD = 1.18) in induced labor between 6 - 10 cm of cervical dilatation. Conclusion: The active phase of labour starts at 6 cm of cervical dilation in the majority of the patients. In multigravida, cervix dilates at faster rate before 6 cm. In induced labour cervix dilates at a slower rate than spontaneous labour after 6 cm dilation.

Cervical dilation and improvement of reproductive performance in fat-tailed ewes via cervical dilator treatments

Objective:To determine the effect of different cervical dilators on cervical dilation and reproductive performance of fat-tailed ewes.Methods: In experiment 1140 ewes were divided into seven groups with seven different treatments as following: 10 mL normal saline (control group), 100 IU oxytocin (OT group), 100 μg estradiol and 100 IU oxytocin (E2+OT group), 5 mL relaxin (R group), 2 mL sensiblex (SEN group), 200 μg misoprostol (MIS group) or 200 μg dinoprostone (DIN group). In experiment 2, artificial insemination was applied for evaluation of reproductive performance in experimental groups.Results: In experiment 1, the highest cervical dilation was observed in OT (90%) and E2+OT (100%) groups (P<0.05), while no significant differences was found among DIN, MIS, SEN and R groups (80%, 75%, 70% and 65%, respectively). In addition, the lowest cervical dilation was observed in control group. Experiment 2 found no significant differences among control, OT and E2+OT groups. The highest pregnancy rate, parturition rate and lambing rate were observed in OT groups (60%, 60% and 70%, respectively) and E2+OT groups (65%, 60% and 70%, respectively) compared to SEN, R, MIS and DIN groups (P<0.05).Conclusions:Oxytocin treatment alone or with estradiol could be used as a suitable dilator for improving reproductive efficiency during artificial insemination in fat-tailed ewes.

Conservative management of cervical pregnancy: The utility of methotrexate treatment and uterine artery embolization

The aim of this retrospective case series report is to evaluate systemic methotrexate therapy in conjunction with uterine artery embolization (UAE) in the conservative management of cervical pregnancy. We examined clinical presentations, treatments, and therapeutic outcomes in fifteen patients with a cervical pregnancy who wished for preservation of fertility, treated at Okayama University Hospital between 1998 and 2012. Twelve patients received systemic methotrexate including five treated with UAE. One was treated with UAE alone. Two patients received neither UAE nor methotrexate because of a low human chorionic gonadotropin (hCG) level and poor blood flow around the gestational sac (GS). An increased GS size and the elevated hCG level during methotrexate therapy might be risk factors for emergent UAE. Two of six patients treated with UAE had subsequent confirmed viable pregnancies. In patients with a cervical pregnancy, methotrexate therapy in combination with UAE can be considered as an option before performing a hysterectomy with suitable counseling about the risk of loss of fertility. Careful observation of the GS size and hCG level during methotrexate therapy might be important for management.

正性暗示语言对宫颈扩张球囊引产孕妇的效果研究

目的探讨正性暗示语言在宫颈扩张球囊引产孕妇中的实施效果。方法选取2023年1月至6月江西省妇幼保健院收治的300例引产孕妇作为研究对象,采用随机数字表法将其分为常规组(150例)和观察组(150例)。对照组采取常规护理,观察组在常规组基础上加用正性暗示语言干预。比较两组孕妇心理状态、舒适度、宫颈成熟程度、妊娠结局和满意度。结果观察组干预后医院焦虑抑郁量表(HADS)评分低于常规组,差异有统计学意义(P<0.05);观察组干预后舒适状况量表(GCQ)评分高于常规组,差异有统计学意义(P<0.05);观察组干预后宫颈Bishop评分高于常规组,差异有统计学意义(P<0.05);观察组自然分娩率为93.33%高于常规组的85.33%,中转剖宫产率为6.67%低于常规组的14.67%,差异有统计学意义(P<0.05);观察组孕妇满意度为96.67%,高于常规组的90.00%,差异有统计学意义(P<0.05)。结论正性暗示语言应用于宫颈扩张球囊引产孕妇中,可促使产妇保持良好心态,增加其身心舒适度,有助于提升宫颈成熟程度,提高自然分娩率,故孕妇对护理服务较为满意。

宫颈癌放疗病人阴道扩张康复措施证据总结

目的:检索、总结并评价宫颈癌放疗病人阴道扩张的相关证据,为临床实施阴道扩张提供证据。方法:按照循证资源“6S”模型,系统检索国内外数据库、指南网及专业协会网站,收集宫颈癌放疗病人阴道扩张相关文献,检索时限为建库至2023年1月15日。结果:共纳入14篇文献,包括2篇专家共识、3篇临床实践、2篇指南、4篇系统评价、3篇随机对照研究,最终从目标人群、扩张准备、扩张时机、扩张频率、注意事项、性健康指导、随访管理与支持7个方面总结出25条证据。结论:总结的宫颈癌放疗病人阴道扩张康复措施的最佳证据具有科学性及实用性,可为医护人员对宫颈癌放疗病人的阴道康复提供循证依据。

子宫颈扩张球囊对妊娠晚期引产促宫颈成熟的临床疗效及安全性观察

目的探讨妊娠晚期足月引产产妇应用子宫颈扩张球囊促宫颈成熟的临床疗效与安全性。方法选取2019年5月至2020年5月于吉安市妇幼保健院分娩的100名足月妊娠引产产妇作为研究对象,按照随机信封法分为对照组与实验组,每组50名。对照组应用催产素引产,实验组应用子宫颈扩张球囊引产。比较两组引产成功率、促宫颈成熟优良率、产程、产后出血量、母婴结局、新生儿出生质量。结果实验组引产成功率、促宫颈成熟优良率均高于对照组,差异有统计学意义(P<0.05)。实验组第一、第二产程及总产程均短于对照组,产后2h出血量少于对照组,差异有统计学意义(P<0.05)。实验组胎儿宫内窘迫、胎盘早期剥离、产褥感染发生率及剖宫产率均低于对照组,差异有统计学意义(P<0.05)。两组新生儿出生后1、5min的Apgar评分比较差异无统计学意义。结论妊娠晚期足月引产产妇应用子宫颈扩张球囊促宫颈成熟的有效性、安全性更高,值得临床推广应用。

Uterine artery pseudoaneurysm caused by hysteroscopic surgery: A case report

BACKGROUND We report a case of uterine artery pseudoaneurysm(UAP)occurrence during hysteroscopic endometrial polypectomy and its treatment via uterine artery embolization(UAE).CASE SUMMARY A 48-year-old primigravid,primiparous patient was incidentally found to have an endometrial polyp during a health checkup,and underwent a hysteroscopic polypectomy at another hospital.Her cervix was dilated with a Laminken-R®device.After the Laminken-R®was withdrawn,a large amount of genital bleeding was observed.This bleeding persisted after the hysteroscopic polypectomy,and,as hemostasis became impossible,the patient was transferred to our hospital by ambulance.On arrival,transvaginal ultrasonography revealed a 3-cm hypoechoic mass with a swirling internal pulse on the right side of the uterus,and color Doppler ultrasonography showed feeder vessels penetrating the mass.Pelvic contrast-enhanced computed tomography(CT)confirmed the presence of a mass at this site,and vascular proliferation was observed within the uterine cavity.Consequently,UAP was diagnosed,and UAE was performed.The patient’s postoperative course was uneventful,and 6 mo post-UAE,no recurrence of blood flow to the UAP was observed.CONCLUSION When abnormal genital bleeding occurs during hysteroscopic surgery,ultrasonography and contrast-enhanced CT can assist in the detection of early UAPs.

宫腔镜术前宫颈软化的临床研究

目的比较宫腔镜术前应用间苯三酚注射液、米索前列醇、一次性宫颈扩张用模具软化宫颈的效果及不良反应。方法选择2020年7月至2022年12月在该院进行宫腔镜手术的150例患者为研究对象,按照随机数字表法分为间苯三酚组(A组)、米索前列醇组(B组)、一次性宫颈扩张用模具组(C组),每组50例。比较3组患者宫颈软化效果、扩宫时间、术中漏水率及不良反应发生率。结果3组患者宫颈软化有效率比较,差异均有统计学意义(P=0.023),A组宫颈软化有效率明显高于B组(P=0.012),C组宫颈软化有效率虽高于B组,但差异无统计学意义(P=0.053)。3组患者扩宫时间比较,差异有统计学意义(P=0.018),A组和C组扩宫时间均短于B组,差异有统计学意义(P=0.008、0.031),A组和C组扩宫时间比较,差异无统计学意义(P=0.600)。3组患者术中漏水率比较,差异无统计学意义(P=0.108)。3组患者不良反应发生率比较,差异有统计学意义(P<0.001)。B组不良反应发生率最高,均明显高于A组与C组(P<0.001、0.011)。结论3种宫颈扩张方法各有利弊,宫腔镜术前需结合手术时间、漏水率、医疗成本、不良反应等综合考虑,选择软化宫颈的方式。

宫颈扩张棒与卡前列甲酯栓对宫颈手术史绝经后妇女取环成功率及宫颈软化度的影响

目的:分析宫颈扩张棒与卡前列甲酯栓在宫颈手术史绝经后妇女中的效果。方法:选取2020年4月至2022年4月于峄城区妇幼保健计划生育服务中心择期行取环术的有宫颈手术史的绝经后妇女68例,按随机数字表法分为两组,各34例。对照组予以宫颈扩张棒,观察组给予卡前列甲酯栓。对比两组一次性取环成功率、术后30min疼痛程度、宫颈软化度。结果:观察组一次性取环成功率[94.12%(32/34)]高于对照组[76.47%(26/34)],术后30min的视觉模拟疼痛量表(VAS)评分[(2.05±0.31)分]低于对照组[(2.67±0.45)分],宫颈软化度[94.12%(32/34)]优于对照组[76.47%(26/34)],有统计学差异(P<0.05)。结论:与宫颈扩张棒相比,卡前列甲酯栓在宫颈手术史绝经后妇女取环术中效果更为显著,可更有效地降低术后疼痛,提高宫颈软化度,获得优良的一次性取环成功率,安全可靠。

子宫颈扩张球囊应用于妊娠晚期女性宫颈成熟和引产的优势评价

目的 评价子宫颈扩张球囊应用于妊娠晚期女性宫颈成熟和引产的优势。方法 方便选取2022年12月—2023年12月武汉真爱妇产医院妇产科引产的62例妊娠晚期产妇,使用随机数字表法分为对照组和研究组,每组31例。对照组患者行缩宫素引产,研究组患者在此基础上行子宫颈扩张球囊引产,对比两组患者的宫颈成熟和引产情况。结果 研究组患者促宫颈成熟有效率(96.77%)高于对照组(80.65%),差异有统计学意义(P<0.05)。研究组患者第一产程时间(7.23±1.67)h、第二产程时间(0.56±0.18)h及总产程时间(8.49±1.35)h短于对照组,产后出血量(210.85±34.41)mL少于对照组,差异有统计学意义(P均<0.05)。研究组患者母婴不良结局总发生率低于对照组,差异有统计学意义(P<0.05)。两组患者并发症总发生率对比,差异无统计学意义(P>0.05)。结论 妊娠晚期应用子宫颈扩张球囊可促进宫颈成熟,提高阴道分娩率,改善母婴结局。

地诺前列酮与宫颈扩张球囊用于足月产妇促宫颈成熟及引产的可行性及安全性分析

目的探讨地诺前列酮与宫颈扩张球囊用于足月产妇促宫颈成熟及引产的可行性及安全性。方法选取2020年1月至2023年3月在徐州医科大学附属徐州市立医院住院分娩的足月产妇80例为研究主体进行前瞻性研究,根据其住院ID号将其分至两组中,即地诺前列酮组与球囊组。地诺前列酮组年龄(28.67±2.17)岁;初产妇30例,经产妇10例;孕周37~41(39.12±1.23)周;采用地诺前列酮栓促宫颈成熟。球囊组年龄(28.44±2.12)岁;初产妇31例,经产妇9例;孕周37~42(39.23±1.19)周;采用宫颈扩张球囊促宫颈成熟。比较两组宫颈Bishop评分、促宫颈成熟效果、分娩情况、不良反应发生情况、引产结局。采用独立样本t检验和χ^(2)检验。结果地诺前列酮组引产后Bishop评分为(8.58±0.51)分,与球囊组(8.62±0.58)分比较,差异无统计学意义(t=0.328,P=0.744);地诺前列酮组总有效率92.50%(37/40),与球囊组95.00%(38/40)比较,差异无统计学意义(χ^(2)=0.213,P=0.644);地诺前列酮组干预至临产时间、第一产程、总产程及干预至阴道分娩时间分别为(14.68±3.81)h、(5.67±2.23)h、(6.12±2.24)h及(34.21±5.49)h,均短于球囊组的(20.22±4.26)h、(7.23±1.12)h、(8.02±1.22)h及(45.25±6.58)h(t=6.131、3.954、4.711、8.148,均P<0.001);球囊组胎膜早破及宫缩过频发生率分别为2.50%(1/40)及0,低于地诺前列酮组的22.50%(9/40)及25.00%(10/40)(χ^(2)=7.314、11.429,均P<0.05);地诺前列酮组与球囊组引产结局比较,差异均无统计学意义(均P>0.05)。结论对于足月分娩的产妇,选择宫颈扩张球囊或地诺前列酮促宫颈成熟及引产都是安全有效的,然而采用地诺前列酮可缩短产妇的临产时间和总产程,适用于需要缩短产程的高危产妇,但其易导致子宫过度刺激及血压波动大,导致产妇宫缩过频、胎膜早破,因此,要根据个体病例选择适宜的方式。

初产妇和经产妇应用子宫颈扩张双球囊引产的结局比较

目的:探讨初产妇和经产妇应用子宫颈扩张双球囊引产的结局。方法:回顾性选取2021年1月—2023年9月郎溪县人民医院接受子宫颈扩张双球囊引产的150例产妇,根据产次分为初产妇组和经产妇组,各75例。比较两组球囊放置到分娩时间、球囊放置前后宫颈Bishop评分、促宫颈成熟有效率、引产效果及新生儿结局。结果:球囊放置后,经产妇组宫颈Bishop评分高于初产妇组,差异有统计学意义(P<0.05);经产妇组球囊放置到分娩时间短于初产妇组,促宫颈成熟总有效率高于初产妇组,差异有统计学意义(P<0.05)。经产妇组剖宫产、阴道助产、继发感染、分娩镇痛、发热的发生率均低于初产妇组,差异有统计学意义(P<0.05)。经产妇组新生儿产伤、新生儿窒息率低于初产妇组,差异有统计学意义(P<0.05)。结论:相比于初产妇,经产妇使用子宫颈扩张双球囊引产的效果更好,且副作用较少。初产妇需寻找更有效地促进宫颈成熟方法,以减少剖宫产率和母婴不良结局。

探讨米索前列醇在妊娠早期人工流产中的应用方法及价值评价

目的探讨米索前列醇在妊娠早期人工流产中的应用价值。方法选取62例行人工流产手术的妊娠早期孕妇,根据随机抽签法分为对照组(采用常规手术)与研究组(采用米索前列醇),每组31例。比较两组不良反应发生率,宫颈扩张效果及临床指标。结果研究组的不良反应发生率为3.23%,对照组不良反应发生率为25.81%,比较差异有统计学意义(P<0.05)。研究组宫颈扩张有效率高于对照组(P<0.05)。研究组术中出血量少于对照组,手术时间短于对照组,且宫缩幅度大于对照组(P<0.05)。结论妊娠早期人工流产孕妇采用米索前列醇,能增强宫缩扩张力,同时具备时效性强及安全可靠价值,值得临床推广。

宫颈扩张球囊及护理干预用于足月引产的临床效果

目的探讨宫颈扩张球囊及护理干预用于足月引产的临床效果。方法选取68例足月引产产妇为研究对象,根据随机数字表法分为两组,各34例。对照组予以常规干预,观察组予以宫颈扩张球囊及护理干预。比较两组产妇干预后诱发临产时间、经阴道分娩率、胎儿窘迫率、护理满意度。结果干预后,观察组诱发临产时间短于对照组,经阴道分娩率高于对照组,胎儿窘迫率低于对照组(P<0.05);观察组护理态度、护理能力、安全管理和护理操作评分高于对照组(P<0.05)。结论宫颈扩张球囊及护理干预用于足月引产的临床效果显著,能有效提高护理满意度,值得推广与应用。

宫颈水囊扩张法与COOK球囊在孕晚期初产妇引产中的应用效果对比

目的对比分析晚期初产妇分别采用宫颈水囊扩张法与COOK宫颈扩张球囊(COOK球囊)进行引产的效果。方法以2022年1月—2023年6月来本院就诊的200例妊娠晚期初产妇为观察对象,按照随机原则对其分组,每组100例。A组采用小剂量缩宫素联合宫颈水囊扩张法引产,B组采取小剂量缩宫素联合COOK球囊导管引产,以产妇治疗12h后宫颈Bishop评分情况为依据,判断其促宫颈成熟效果,并对其治疗有效性进行评价,观察产妇诱发宫缩至临床时间、第一产程、总产程时间及其不良妊娠结局等,对比两种引产方法的有效性与安全性。结果A组产妇治疗阴道分娩率与B组相比较高,剖宫产率与B组相比较低(P<0.05),且A组产妇诱发宫缩至临床时间、第一产程时间与总产程时间都短于B组(P<0.05),但两组12h宫颈Bishop评分、产后出血率、宫内窘迫率与宫颈裂伤率与B组无明显差异(P>0.05)。结论妊娠晚期初产妇采用宫颈水囊扩张法与COOK球囊均可有效促进宫颈成熟、缩短产程并提高阴道分娩率,改善产妇的不良妊娠结局,保障产妇引产安全性,宫颈单水囊扩张法在改善宫颈成熟度方面更为理想,舒适度更高。

Dilation of a severe bilioenteric or pancreatoenteric anastomotic stricture using a Soehendra Stent Retriever

Bilioenteric or pancreatoenteric anastomotic stric-tures often occur after surgery for a pancreaticobiliary disorder. Therapeutic endoscopic retrograde cholan-giopancreatography using balloon enteroscopy has been shown to be feasible and effective in patients with such strictures. However, when a benign anas-tomotic stricture is severe, a dilation catheter cannot pass through the stricture despite successful insertion of the guidewire. We report on the usefulness of the Soehendra Stent Retriever over a guidewire for dilating a severe bilioenteric or pancreatoenteric anastomotic stricture under short double-balloon enteroscopy, in two patients with surgically altered anatomies.

双胎妊娠紧急子宫颈环扎术妊娠结局的研究

目的:探讨双胎妊娠紧急子宫颈环扎术(CC)的临床疗效。方法:收集2004年1月至2021年12月于北京大学第一医院就诊并分娩的双胎妊娠孕16~27^(+6)周宫口开大1~4 cm行紧急CC的30例孕妇的临床资料,依据CC的孕周分为<24周组(19例)和≥24周组(11例)。比较两组的CC疗效,以是否获得活产儿分为成功组(23例)和失败组(7例),分析影响CC分娩结局的相关因素。结果:①30例双胎妊娠紧急CC后的分娩孕周29.5±5.2周,围产儿死亡率25.0%,延长孕周6.8±4.4周。②孕周≥24周组孕妇的CC孕周(24.7±0.8周vs.21.7±1.6周)、分娩孕周(31.6±2.8周vs.28.3±6.0周)及活产率(100.0%vs.63.2%)明显高于<24周组,差异有统计学意义(P<0.05)。③多因素Logistics回归分析示,术前超声检查宫腔内絮状回声、术后白细胞计数(WBC)≥10×10^(9)/L是双胎妊娠紧急CC失败的独立危险因素(OR>1,P<0.05),CC孕周≥24周是保护性因素(OR<1,P<0.05)。结论:双胎妊娠孕周≥24周后行紧急CC仍有临床价值,必要时双胎妊娠行紧急CC可以在孕24~27^(+)周进行。CC孕周<24周、术前超声检查提示宫腔内絮状回声、术后WBC≥10×10^(9)/L者双胎妊娠紧急CC失败的风险升高。

初次宫颈环扎后宫口再次扩张≤2cm行重复宫颈环扎术的临床观察

目的:探究初次宫颈环扎后宫口再次扩张≤2cm行重复宫颈环扎术的临床效果。方法:回顾性分析2016年1月至2020年12月于我院初次行McDonald’s宫颈环扎术后再次出现宫口扩张的36例宫颈机能不全患者的临床资料。所有患者均行重复宫颈环扎术治疗。根据患者初次宫颈环扎后宫口再次扩张≤2cm(15例)和>2cm(21例)分为两组。统计所有患者的妊娠及分娩结局,并比较两组患者的人口统计学特征及妊娠结局。结果:初次宫颈环扎后宫口再次扩张≤2cm患者的重复环扎后孕周延长、从诊断到分娩孕周延长、分娩孕周长于初次宫颈环扎后宫口再次扩张>2cm患者,新生儿出生体重、新生儿存活率均高于初次宫颈环扎后宫口再次扩张>2cm患者,差异有统计学意义(P<0.05);两组患者的年龄、初产妇、顺娩次数、>14周流产次数比较,差异无统计学意义(P>0.05)。结论:初次宫颈环扎后宫口再次扩张≤2cm行重复宫颈环扎术可以延长宫颈机能不全患者的孕周,改善其妊娠结局及新生儿结局。

宫颈扩张球囊和缩宫素对足月妊娠促宫颈成熟和分娩结局的影响

目的 比较宫颈扩张球囊和缩宫素对足月妊娠宫颈成熟和分娩结局的影响。方法 将122例孕足月产妇随机等分为球囊组(宫颈扩张球囊引产)和缩宫素组(缩宫素引产),比较两组的促宫颈成熟总有效率、分娩结局、凝血因子水平和分娩期间并发症。结果 球囊组引产后Bishop评分和促宫颈成熟总有效率高于缩宫素组(P<0.05)。球囊组阴道分娩率、新生儿Apgar评分高于缩宫素组,剖宫产率、羊水污染率、引产到临产时间、产程时间均小于缩宫素组(P<0.05)。治疗后3天缩宫素组凝血指标和产后出血量优于球囊组(P<0.05)。结论 宫颈扩张球囊较缩宫素可更有效促足月妊娠宫颈成熟,改善分娩结局,缩宫素可有效预防产后出血,增强凝血功能,临床可根据实际情况单用或联用。