New Abnormal Cervical Cell Detection Method of Multi-Spectral Pap Smears

Considering the problem of traditional cervical cancer detection method that brings high false negative rate （FNR） and high false positive rate （FPR）, a new abnormal cervical cells detection method of multi-spectral Pap smear is proposed in this thesis, on the basis of multi-spectral microscopic imaging technology and computer automotive recognition technology. At first, image in a specific wave band is segmented according to the relationship between intensity and spectrum of each pixel. Then, multi-spectral features of each pixel are extracted making use of improved cosine correlation analysis （CCA） algorithm. Combined with the characteristic of each cell＇s area, final definition is made. Experiments have proved the new approach could identify abnormal cells efficiently as well as lower FNR and FPR.

Retrospective study on the efficacy and safety of quinacrine sterilization

Aim: To observe the efficacy and safety of quinacrine sterilization.Methods: This retrospective study was to evaluate the efficacy and safetyof quinacrine sterilization in 572 cases in Jiangsu and Guizhou Provincesfrom 1993 to 1997. A total of 588 cases of surgical sterilization performed atthe same time served as the controls. Results: Two groups had similardemographic and gynecological characteristics. The multiple decrement lifetable analysis showed that the 12th month gross cumulative failure rate forquinacrine sterilization was 3.13% . Serious side effects occurred in 2 cases(0.35%); one is ectopic pregnancy (20 months after treatment) and theother, allergy reaction (10 minutes after the second insertion). The liverand renal functions were all normal in both groups. No cance cells/suspect-ed cancer cells were found. In the quinacrine group, the acceptability was99.6% . Conclusions: The quinacrine method has a high acceptability,but the efficacy is relatively low. It is a safe method of contraception inshort-term study, while the long-term safety warrants further investigation.

Retrospective Study on the Efficacy and Safety of Quinacrine Sterilization

Objective To observe and evaluate the efficacy and safety of quinacrine sterilization Methods A total of 572 cases of quinacrine sterilization preformed during the 4 years from 1993 to 1997 in Jiangsu and Guizhou Provinces were employed in this study. The efficacy and safety of quinacrine sterilization in those case were studied and evaluated, with 588 cases of surgical sterilization performed at the same time being the control group. Results Both groups were with identical demographic and gynecological characteristics. The result of multiple decrement life table analysis showed the 12th gross cumulative failure rates for quinacrine sterilization was 3.13% and serious side effects occurred in only 2 cases accounting for 0.35%. One was ectopic pregnancy (20 months after treatment).The other was due to anaphylaxis in 10 minutes after the second insertion). No difference in the liver and nephic functions was detected and no suspected cancer cells or cancer cells were found in the two groups. 99.6% of the 572 women interviewed accepted the quinacrine sterilization. Conclusions Quinacrine sterilization method is with high acceptability but comparatively low effectiveness. It has been proved to be a safe method of contraception in short term. However, the safety of long term still needs further study.