A rat model of extra-vertebral foramen cervical nerve entrapment was established according to the following parameters： stimulation intensity 20 V; frequency 50 Hz; pulse width 200 μs; duration 333 ms/s for a total ...A rat model of extra-vertebral foramen cervical nerve entrapment was established according to the following parameters： stimulation intensity 20 V; frequency 50 Hz; pulse width 200 μs; duration 333 ms/s for a total of 8 hours. After the electrical stimulation, rats exhibited mild muscle fiber atrophy, mild inflammatory exudates, connective tissue local fibrosis and chondrocyte metaplasia. Mean muscle fiber cross-sectional area was reduced. The nerve myelin sheath continuity was partially demyelinated. The microstructure of nerve cells was disrupted and these symptoms worsened with prolongation of the stimulation. The shoulder, neck and upper extremity muscles on the tested side demonstrated positive sharp waves and fibrillations. The severity increased with continuation of the stimulation. High amplitude and polyphasic motor unit potentials gradually appeared. Similar findings were seen in the contralateral side, but at a less severe level.展开更多
目的探讨局部正骨推拿联合针灸治疗颈肩腰腿痛的临床疗效及对疼痛程度、活动功能的影响。方法便利选取2021年5月—2023年3月福建省龙岩人民医院收治的120例颈肩腰腿痛患者为研究对象,依据随机数表法分组,每组60例,对照组给予局部正骨推...目的探讨局部正骨推拿联合针灸治疗颈肩腰腿痛的临床疗效及对疼痛程度、活动功能的影响。方法便利选取2021年5月—2023年3月福建省龙岩人民医院收治的120例颈肩腰腿痛患者为研究对象,依据随机数表法分组,每组60例,对照组给予局部正骨推拿治疗,观察组在对照组基础上联合针灸治疗。比较两组临床疗效,治疗期前后疼痛程度、各功能量表评分、生活质量。结果治疗后,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组视觉模拟评分法(Visual Analogue Scale,VAS)评分(1.93±0.42)分低于对照组的(3.07±0.75)分,差异有统计学意义(t=10.273,P<0.05)。观察组颈椎病临床评价量表(Clinical Evaluation Scale for Cervical Spondylosis,CASCS)评分、肩关节功能评价量表(Shoulder Joint Function Assess-ment Scale,C-M)评分、日本改良颈椎腰腿痛评分法(Japan Modified Cervical Low Back and Leg Pain Scale,M-JOA)评分、Lysholm膝关节评分表(Lysholm Knee Scale,Lysholm)评分均高于对照组,差异有统计学意义(P<0.05)。观察组Barthel指数高于对照组,差异有统计学意义(P<0.05)。结论局部正骨推拿联合针灸治疗颈肩腰腿痛临床疗效显著,可减轻患者疼痛,改善患者颈肩腰腿功能,促进生活质量提升。展开更多
基金the National Natural Science Foundation of China,No. 81171707the Major State Basic Research Program of China,No.2012CB933600+2 种基金Shanghai Pujiang Program,No.11PJD016China Postdoctoral Science Foundation,No. 20090460629Fund for Key Disciplines of Shanghai Municipal Education Commission,No.J50206
文摘A rat model of extra-vertebral foramen cervical nerve entrapment was established according to the following parameters： stimulation intensity 20 V; frequency 50 Hz; pulse width 200 μs; duration 333 ms/s for a total of 8 hours. After the electrical stimulation, rats exhibited mild muscle fiber atrophy, mild inflammatory exudates, connective tissue local fibrosis and chondrocyte metaplasia. Mean muscle fiber cross-sectional area was reduced. The nerve myelin sheath continuity was partially demyelinated. The microstructure of nerve cells was disrupted and these symptoms worsened with prolongation of the stimulation. The shoulder, neck and upper extremity muscles on the tested side demonstrated positive sharp waves and fibrillations. The severity increased with continuation of the stimulation. High amplitude and polyphasic motor unit potentials gradually appeared. Similar findings were seen in the contralateral side, but at a less severe level.
文摘目的探讨局部正骨推拿联合针灸治疗颈肩腰腿痛的临床疗效及对疼痛程度、活动功能的影响。方法便利选取2021年5月—2023年3月福建省龙岩人民医院收治的120例颈肩腰腿痛患者为研究对象,依据随机数表法分组,每组60例,对照组给予局部正骨推拿治疗,观察组在对照组基础上联合针灸治疗。比较两组临床疗效,治疗期前后疼痛程度、各功能量表评分、生活质量。结果治疗后,观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组视觉模拟评分法(Visual Analogue Scale,VAS)评分(1.93±0.42)分低于对照组的(3.07±0.75)分,差异有统计学意义(t=10.273,P<0.05)。观察组颈椎病临床评价量表(Clinical Evaluation Scale for Cervical Spondylosis,CASCS)评分、肩关节功能评价量表(Shoulder Joint Function Assess-ment Scale,C-M)评分、日本改良颈椎腰腿痛评分法(Japan Modified Cervical Low Back and Leg Pain Scale,M-JOA)评分、Lysholm膝关节评分表(Lysholm Knee Scale,Lysholm)评分均高于对照组,差异有统计学意义(P<0.05)。观察组Barthel指数高于对照组,差异有统计学意义(P<0.05)。结论局部正骨推拿联合针灸治疗颈肩腰腿痛临床疗效显著,可减轻患者疼痛,改善患者颈肩腰腿功能,促进生活质量提升。
