Effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section

Objective:To discuss the effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section. Methods:70 patients with postpartum hemorrhage after placenta previa cesarean section who were treated in Chengdu Women & Children's Central Hospital between January 2014 and February 2017 were collected and then divided into the control group (n=35) who received uterine packing therapy and the observation group (n=35) who received Hemabate combined with packing therapy according to random number table. Serum levels of oxidative stress indexes and stress hormones immediately after operation and 24 h after operation were compared between two groups of patients.Results: Immediately after operation and 24 h after operation, serum oxidative stress indexes ROS and MDA levels of observation group were significantly lower than those of control group while SOD, GSH-px and CAT levels were significantly higher than those of control group, and serum stress hormones NE, E and Cor levels were significantly lower than those of control group.Conclusion: Hemabate combined with packing therapy can effectively reduce systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section, is a more ideal way of the bleeding.

Relationship between Placenta Location and Resolution of Second Trimester Placenta Previa

This prospective study was conducted to assess the rate of resolution of second trimester placenta previa in women with anterior placenta and posterior placenta, and that in women with and without previous cesarean section. In this study, placenta previa was defined as a placenta lying within 20 mm of the internal cervical os or overlapping it. We recruited 183 women diagnosed with previa between 20+0 weeks and 25+6 weeks. They were grouped according to their placenta location(anterior or posterior) and history of cesarean section. Comparative analysis was performed on demographic data, resolution rate of previa and pregnancy outcomes between anterior group and posterior group, and on those between cesarean section group and non-cesarean section group. Women with an anterior placenta tended to be advanced in parity(P=0.040) and have increased number of dilatation and curettage(P=0.044). The women in cesarean section group were significantly older(P=0.000) and had more parity(P=0.000), gravidity(P=0.000), and dilatation and curettage(P=0.048) than in non-cesarean section group. Resolution of previa at delivery occurred in 87.43% women in this study. Women with a posterior placenta had a higher rate of resolution(P=0.030), while history of cesarean section made no difference. Gestational age at resolution was earlier in posterior group(P=0.002) and non-cesarean section group(P=0.008) than in anterior group and cesarean section group correspondingly. Placenta location and prior cesarean section did not influence obstetric outcomes and neonatal outcomes. This study indicates that it is more likely to have subsequent resolution of the previa when the placenta is posteriorly located for women who are diagnosed with placenta previa in the second trimester.

Clinical Analysis on the Effectiveness of Conservative Compression Suture Technique to Conserve Fertility on Pernicious Placenta Previa

Objective: To evaluate the effectiveness of conservative compression surgical suture techniques used for the management of pernicious placenta previa to conserve fertility in the subsequent pregnancies. Study Design: This was a non-comparative retrospective study of 188 patients diagnosed with pernicious placenta previa who underwent cesarean section in The First Hospital of Jilin University, China, from 1 January 2013 to 1 January 2018. Successful group was defined as those in which the intraoperative bleeding was managed by either modified CHO or by B-lynch suture technique and those who had further intervention including hysterectomy were designated as failure group. Results: Out of 217 patients, 188 met inclusion criteria and 29 patients were excluded. In 188 cases, 183 (97.34%) cases successes and 5 (2.65%) cases had hysterectomy. Among included group, 118 patients (62.76%) had undergone emergency cesarean section and 70 patients (37.23%) underwent elective cesarean section. The emergency group had significantly lesser gestation period of gestation at the time of cesarean section (P = 0.021) and lower neonatal weight (P = 0.001) than that of elective group. The estimated blood loss during surgery was 500 - 3200 ml (mean: 925 ml). Additionally, the amount of bleeding was found to be significantly more in patient with intraoperative complication (P = 0.007) and in patient with implanted placenta (P 0.001). Conclusion: The conservative compression suture technique including modified CHO and B-lynch suture technique during the cesarean delivery is a feasible, safe and effective alternative conservative surgical technique for the management of bleeding in case of pernicious placenta previa. Besides good surgical outcome and proper neonatal result this technique also reduces the rate of hysterectomy, thus conserving the fertility.

Clinical analysis of 322 cases of placenta previa

In recent years, the incidence of placenta previa has been increasing. According to the literature, it is mainly related to induced labor, artificial abortion, cesarean section, high aging pregnancy, multipara or smoking. The placenta previa is the chief cause of bleeding in late pregnancy and threatens the lives of mother and infant, resulting in a high risk problem in obstetrics. This article studies 322 cases of placenta previa from my hospital and Dalian Obstetrics and Gynecological Hospital from January, 2002 to July, 2009, on the basis of clinicretrospective analysis, in order to deepen our understanding and art of treating placenta previa. The study revealed that: 1. With 322 cases of placenta previa, the incidence was 0.73%. It was higher than the incidence 0.3% reported abroad and lower than the incidence 0.94% reported in our country. The data were from sampling survey and did not prove relations between placenta previa and ages, different from the result obtained abroad in which placenta previa had relation with pregnancy ages. The outcome needs further study. But artificial abortion, induced labor, cesarean section and multipara clearly influence the incidence. The study did not analyze the relation between smoking and placenta previa, but there was external data proving that smoking was related to placenta previa; 2. Ultrasound-B is a better method for examination at present; 3. In cases of vaginal childbirth there was a higher incidence of lateral placenta previa and partial placenta previa. The conservative temporization and timely cesarean section can greatly decrease the mortality of mother and infant.

Comparison of cell salvage with one and two suction devices during cesarean section in patients with placenta previa and/or accrete: a randomized controlled trial

Background:Cell salvage has recently been recommended for obstetric use in cases with a high risk of massive hemorrhage during cesarean section(CS).However,limited data are available to support the use of one suction device to collect lost blood.This study aimed to investigate the volume of red blood cells(RBCs)salvaged and the components of amniotic fluid(AF)in blood salvaged by one suction device or two devices during CS in patients with placenta previa and/or accrete.Methods:Thirty patients with placenta previa and/or accrete undergoing elective CS in the Women's Hospital of Zhejiang University School of Medicine were recruited for the present study from November 1,2017 to December 1,2018.The patients were randomly assigned to one of the two groups according to an Excel-generated random number sheet:Group 1(w=15),in which only one suction device was used to aspirate all blood and AF,and Group 2(w=15),in which a second suction device was mainly used to aspirate AF before the delivery of the placenta.Three samples of blood per patient(pre-wash,post-wash,and post-filtration)were collected to measure AF components.The salvaged RBC volumes were recorded.Continuous data of pre-wash,post-wash,and postfiltration samples were analyzed by using one-way analysis of variance with Tukey5s test for multiple comparisons,or Kruskal-Wallis test with Dunn test for multiple comparisons.Comparisons of continuous data between Group 1 and Group 2 were conducted using Student's t test or Mann-Whitney U test.Results:The salvaged RBC volume was significantly higher in Group 1 than that in Group 2(401.6±77.2 mL vs.330.1土53.3 mL,?=4.175,P<0.001).In both groups,squamous cells,lamellar bodies,and fat were significantly reduced by washing(all P<0.001)and squamous cells were further reduced by filtering(P<0.001).Squamous cells were found in six post-filtration samples(three from each group).Lamellar bodies and fat were completely removed by filtering.Insulin-like growth factor binding protein 1,alphafetoprotein,albumin,lactate dehydrogenase,and potassium were significantly reduced post-wash(all P<0.05),with no further significant reduction after filtration in either group(all P>0.05).The mean percentage of fetal RBCs post-filtration was(1.8±0.8)%with a range of 1.0%to 3.5%and(1.9±0.9)%with a range of 0.7%to 4.0%in Groups 1 and 2,respectively,showing no significant difference between the two groups(U=188.5,P=0.651).Conclusion:Cell salvage performed by one suction device could result in higher volume of salvaged RBCs and can be used safely for CS in patients with placenta previa and/or accrete when massive hemorrhage occurs.Trial registration number:ChiCTR-INR-17012926,http://www.chictr.org.cn/Chinese Clinical Trial Registry.

Application of Modified Cesarean Hysterectomy for Patients with Placenta Previa Complicated with Placenta Percreta

Objective::To evaluate the efficacy and safety of a modified cesarean hysterectomy(MCH)procedure in controlling hemorrhage in patients with placenta previa complicated with placenta percreta.Methods::A retrospective analysis was conducted on 23 patients with placenta previa complicated with placenta percreta from January 2016 to December 2018 in the Union Hospital.The patients’age ranged from 24 to 41 years,and had gestational durations of 32-38 weeks.Nine of them underwent MCH and 14 underwent conventional cesarean hysterectomy(CCH).In the MCH group,the bladder was not mobilized,deliberately.The uterus was excised horizontally above the tourniquet level.Placental tissue around the cervical os was cleaned thoroughly,and hemostatic suturing was performed under direct vision.In the CCH group,the uterus was removed gradually after programmed hemostasis and dissection of adhesions of the vesicouterine peritoneal fold and mobilization of the bladder.Results::There were no significant differences in general conditions between the two groups.The blood loss was significantly less in the MCH group(P<0.05).The operation time was also decreased dramatically and hospital stay(in days)was shorter than in the CCH group(P<0.05).There were no bladder or ureter injuries in the MCH group,compared with three cases in the CCH group.There were no statistically significant differences in neonatal birth weight,Apgar score,or intensive care unit admittance rates between the two groups(P>0.05).Conclusion::This MCH procedure reduced blood loss,avoided bladder injury,and had no long-term complications.It is a safe,rapid,and effective way to control fatal hemorrhage during surgery for women with placenta previa complicated with placenta percreta.

腰硬联合麻醉下凶险性前置胎盘剖宫产术低血压发生的诱导因素及列线图预测模型的构建

目的探讨腰硬联合麻醉(CSEA)下凶险性前置胎盘剖宫产术中低血压发生的诱导因素并构建列线图预测模型。方法选取玉林市妇幼保健院2020年1月—2023年12月收治的腰硬联合麻醉(CSEA)下凶险性前置胎盘剖宫产术产妇130例作为研究对象,采用自编的一般资料调查表对研究对象基本资料及低血压发生情况进行调查,并依据术中低血压发生情况将其分为低血压组47例和无低血压组83例。对2组一般资料进行单因素分析,采用多因素Logistic回归分析法探讨术中发生低血压的诱导因素。结果单因素分析显示,2组体质量指数、麻醉平面情况、是否为多胎妊娠、术前收缩压情况、手术时间、是否出现Bezold-Jarisch反射比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析显示,体质量指数≥24 kg/m^(2)、麻醉平面≥T8、多胎妊娠、术前收缩压<90 mmHg、手术时间>1.5 h、出现Bezold-Jarisch反射是CSEA下凶险性前置胎盘产妇剖宫产术中发生低血压的独立危险因素(P<0.05)。构建CSEA下凶险性前置胎盘剖宫产术中低血压发生的诱导因素回归方程:Logit(P)=-23.211+1.079×(体质量指数≥24 kg/m^(2))+1.101×麻醉平面(≥T8)+3.193×多胎妊娠+2.214×术前收缩压(<90 mmHg)+4.606×手术时间(>1.5 h)+2.011×出现Bezold-Jarisch反射。分析发现列线图对于存在术前收缩压<90 mmHg人群均有较高区分度及准确度;对列线图模型进行Bootstrap重复抽样1000次,获得校准曲线,计算得到的一致性指数为0.850,说明该列线图模型具备较好的校准度;绘制受试者工作特征(ROC)曲线,其曲线下面积为0.896,95%CI为0.802~0.956,提示预测效能较好。结论体质量指数≥24 kg/m^(2)、麻醉平面≥T8、多胎妊娠、术前收缩压<90 mmHg、手术时间>1.5 h、出现Bezold-Jarisch反射是CSEA下凶险性前置胎盘产妇剖宫产术中低血压发生的诱导因素。

植入型凶险型前置胎盘计划性剖宫产术中子宫动脉结扎阻塞及宫腔填充术的有效性和安全性

目的探究植入型凶险型前置胎盘计划性剖宫产术中采用子宫动脉结扎阻塞及宫腔填充术的有效性和安全性。方法选取2019年12月至2021年12月唐山市妇幼保健院收治的132例植入型凶险型前置胎盘计划性剖宫产术治疗患者为研究对象,按不同的血管阻断方式分为子宫动脉栓塞术联合宫腔填充治疗组(对照组)和子宫动脉结扎联合宫腔填充治疗组(观察组),观察比较两组患者的手术时间、术中出血量、术中输血量、膀胱损伤率,并观察记录两组母婴结局情况,包括新生儿1min Apgar评分、子宫切除率、凝血功能异常发生率。记录患者术后不良反应的发生情况,包括发热、慢性盆腔疼痛、伤口愈合不良、术后血栓形成、月经量降低等。结果观察组患者的手术时间、膀胱损伤率均较对照组更低(t=4.428和5.621,P<0.05),术中出血量、术中输血量未见显著差异(t=1.472和1.729,P>0.05),两组新生儿出生1min Apgar评分未见显著差异(t=0.257,P>0.05),但观察组产妇的子宫切除率、凝血功能异常发生率显著低于对照组(t=3.722和4.628,P<0.05),两组患者均未发生严重的产科并发症,其中观察组患者发热、慢性盆腔疼痛、术后血栓形成、伤口愈合不良、术后月经量降低的发生率均显著低于对照组,差异具有统计学意义(t=6.274、4.726、3.872、3.872和4.218,P<0.05)。结论子宫动脉结扎术和子宫动脉造影栓塞术对植入型凶险型前置胎盘患者具有一定的临床疗效,其中子宫动脉结扎手术时间短,术后并发症发生率低,具有较好的有效性和安全性。

1例凶险性前置胎盘行双侧骼内动脉球囊封堵联合剖宫产术后并发DIC的护理

总结1例凶险性前置胎盘行双侧骼内动脉球囊封堵联合剖宫产术后并发弥散性血管内凝血(DIC)的护理。通过多学科团队的联合诊治及护理,病人病情平稳出院。随访半年,病人状况良好。

不同性质球囊髂内动脉阻断术在凶险性前置胎盘剖宫产中的对比研究

目的 比较不同性质球囊髂内动脉阻断术在凶险性前置胎盘(PPP)剖宫产中的应用效果。方法 回顾性分析82例PPP患者的临床资料,其中观察组40例,给予双侧髂内动脉顺应性Fogarty球囊阻断术;对照组42例,给予非顺应性球囊髂内动脉阻断术。比较两组患者在髂内动脉阻断术前、术后收缩压及心率、X线透视时间、胎儿体表辐射剂量、剖宫产时间、术中出血量及输血量、子宫动脉栓塞率、子宫切除率和1、5、10 min新生儿Apgar评分以及术后住院时间及手术相关并发症。结果 两组患者子宫均成功保留,均成功行双侧髂内动脉球囊阻断术辅助剖宫产手术顺利完成。撤出球囊导管,部分患者行子宫动脉栓塞术,无患者行卵巢动脉栓塞及子宫切除术。两组患者术前、术后收缩压和心率组间比较差异均无统计学意义,但两组术后收缩压、心率低于术前,均P<0.05。两组X线透视时间、胎儿体表辐射剂量、子宫动脉栓塞率、子宫切除率和1、5、10 min新生儿Apgar评分以及术后住院时间对比差异均无统计学意义,观察组剖宫产时间、术中出血量、术中输血量低于对照组,均P<0.05。两组患者球囊阻断术后其相关并发症发生率比较差异均无统计学意义。结论 不同性质髂内球囊动脉阻断术辅助在PPP剖宫产均安全有效,但双侧髂内动脉顺应性球囊阻断术在减少剖宫产手术时间、术中出血量、术中输血量等方面更具优势。

剖宫产术中不同时机行血管介入阻断对凶险性前置胎盘患者及胎儿影响的Meta分析

目的系统评价剖宫产术中不同时机行血管介入阻断对凶险性前置胎盘患者及胎儿的影响。方法采用计算机检索PubMed、Embase、Medline、Web of Science、维普、万方数据库、中国知网、中国生物医学文献数据库等中不同时机行血管介入阻断对凶险性前置胎盘的相关研究。检索时限为建库至2024年3月1日,由两名研究员独立筛选随机对照或回顾性文献、提取数据,选用Review Manager 5.4.1软件分析,参照Cochrane协作网提供的偏倚风险评估工具对文献质量进行评估。结果共纳入12篇目标文献,1030例凶险性前置胎盘患者。Meta分析结果显示,胎儿娩出前阻断可降低术后子宫切除率(OR=0.54,95%CI:0.33~0.89)和术后入住ICU病房率(OR=0.34,95%CI:0.19~0.63),但不能降低序贯子宫动脉栓塞率(OR=0.61,95%CI:0.28~1.32)。此外,对胎儿1 min Apgar评分(MD=0.11,95%CI:-0.23~0.46)、5 min Apgar评分(MD=0.10,95%CI:-0.04~0.24)、1 min Apgar评分≤7分(OR=0.81,95%CI:0.36~1.85)、5 min Apgar评分≤7分(OR=0.93,95%CI:0.33~2.63)无明显影响。结论胎儿娩出前介入阻断的临床价值更高,且不会增加胎儿不良结局。

宫腔球囊联合水囊放置术在前置胎盘剖宫产后出血患者中的应用

目的探讨宫腔球囊联合水囊放置术在前置胎盘剖宫产后出血患者中的应用效果。方法选取2019年1月至2024年2月在濮阳县人民医院妇产科接受宫腔球囊联合水囊放置治疗的38例前置胎盘剖宫产后出血孕妇作为研究组,同期采用宫腔水囊放置治疗的38例前置胎盘剖宫产后出血孕妇作为对照组。比较两组孕妇产后24h的止血效果、手术指标(产妇控制出血时间、填塞至产后24h出血量、填塞物放置时间和住院时间),术前及术后24h的产妇血红细胞及血红蛋白浓度和术后并发症发生情况。结果产后24h,研究组孕妇的止血总有效率为100.00%,略高于对照组的94.74%,但差异无统计学意义(P>0.05);研究组孕妇的控制出血时间、填塞至产后24 h出血量、填塞物放置时间分别为(15.29±3.28)min、(80.04±10.17)mL、(28.17±1.93)h,明显少于对照组的(20.03±3.14)min、(84.19±12.04)mL、(30.08±2.47)h,差异均有统计学意义(P<0.05),而两组产妇的住院时间比较差异无统计学意义(P>0.05);两组孕妇术前红细胞、血红蛋白水平比较差异均无统计学意义(P>0.05);术后24h,两组孕妇的红细胞、血红蛋白水平均低于术前,差异均有统计学意义(P<0.05),但两组孕妇间术后24 h的红细胞、血红蛋白水平比较差异均无统计学意义(P>0.05);研究组孕妇术后并发症发生率为2.63%,略低于对照组的10.53%,但差异无统计学意义(P>0.05)。结论宫腔水囊放置术治疗前置胎盘剖宫产后出血的止血效果与宫腔球囊联合水囊放置术相似,但宫腔球囊联合水囊放置控制出血时间及填塞至产后24h出血量更少,填塞物放置时间更短,安全性均较高,临床可结合孕妇实践情况灵活选择治疗方式。

PAS产前超声分级系统及子宫动脉超声参数在凶险性前置胎盘患者术前评估中的价值

目的评估胎盘植入性疾病(PAS)产前超声分级系统及子宫动脉超声参数在凶险性前置胎盘患者术前评估中的用价值。方法选取2020年2月—2022年11月三亚市妇幼保健院收治的92例凶险性前置胎盘患者作为研究对象,根据PAS产前超声分级将患者分为≤PAS-4组(1~4级)和>PAS-4组(5、6级),其中≤PAS-4组患者52例,>PAS-4组患者40例。比较两组患者一般临床资料、超声指标特征,采用多因素一般Logistic回归模型分析其在凶险性前置胎盘患者术前评估中的应用价值。结果≤PAS-4组既往剖宫产次数少于>PAS-4组,完全性凶险型比例低于>PAS-4组,血流搏动指数(PI)、血液流动阻力(RI)高于>PAS-4组(P<0.05)。≤PAS-4组子宫膀胱间高度血管化、胎盘后高度血管化、局部组织外生、胎盘陷窝支流血管、胎盘增厚、宫颈膨大、胎盘后间隙消失比例低于>PAS-4组(P<0.05)。多因素一般Logistic回归分析结果显示:PI高[O^R=0.961(95%CI:0.848,0.983)]、RI高[O^R=0.867(95%CI:0.839,0.923)]、既往剖宫产次数多[O^R=4.568(95%CI:2.012,7.609)]均是凶险性前置胎盘患者PAS产前超声分级>4级的影响因素(P<0.05)。联合预测凶险性前置胎盘患者PAS产前超声分级>4级的曲线下面积最高,为0.929(95%CI:0.881,0.977),其次为既往剖宫产次数;RI敏感性最高,为0.910(95%CI:0.711,0.953),其次为PI;联合预测特异性最高,为0.956(95%CI:0.727,0.975),其次为既往剖宫产次数。结论PI、RI、既往剖宫产次数指标在术前对凶险性前置胎盘PAS 4级以上患者有较好的预测价值,为术前制订手术方案提供了可靠的依据,可降低此类患者的手术并发症风险。

回收式自体输血在前置胎盘剖宫产术中应用价值的Meta分析

目的荟萃分析回收式自体输血(IOCS)在前置胎盘剖宫产术中的安全性和有效性。方法计算机检索PubMed、Web of Science、Embase、the Cochrane Library of clinical trials、中国知网(CNKI)及万方数据知识服务平台。检索时限设定为建库至2022年12月。采用R 4.1.2与Stata 12.0软件计算IOCS组和异体输血(ABT)组之间的标准化均数差(SMD)或相对危险度(RR)及95%置信区间(CI)和预测区间(PI)。结果本次Meta分析共纳入5项随机对照试验和10项回顾性队列研究。队列研究的合并结果显示,与ABT组相比,接受IOCS的前置胎盘孕产妇术后血红蛋白(Hb)浓度(SMD=0.626,95%CI:0.103~1.149;95%PI:-1.320~2.572)与红细胞压积较高(SMD=0.617,95%CI:0.130~1.104;95%PI:-1.084~2.317)。在随机对照试验中,接受IOCS的前置胎盘孕产妇发生不良事件的风险比ABT组低72.7%(RR=0.273,95%CI:0.082~0.904)。IOCS组和ABT组术后凝血酶原时间(PT)、活化凝血酶原时间(APTT)、纤维蛋白原(Fib)浓度、血尿素氮(BUN)和肌酐(Cr)差异均无无统计学意义。结论接受IOCS的前置胎盘孕产妇术后Hb浓度和Hct均高于接受ABT的妇女。IOCS对术后凝血参数和肾功能参数无显著影响。在接受剖宫产术的前置胎盘孕产妇中,IOCS与较低的输血相关不良事件发生风险有关。

Effect of Primary Elective Cesarean Delivery on Placenta Accreta： A Case-Control Study

Background： Cesarean section （CS） is an independent risk factor for placenta accreta. Some researchers think that the timing of primary cesarean delivery is associated with placenta accreta in subsequent pregnancies. The aim of this study was to investigate the risk of placenta accreta following primary CS without labor, also called primary elective CS, in a pregnancy complicated with placenta previa. Methods： A retrospective, single-center, case-control study was conducted at Peking University Third Hospital. Relevant clinical data of singleton pregnancies between January 2010 and September 2017 were recorded. The case group included women with placenta accreta who had placenta previa and one previous CS. Control group included women with one previous CS that was complicated with placenta previa. Maternal age, body mass index, gestational age, fetal birth weight, gravity, parity, induced abortion, the rate of women received assisted reproductive technology, other uterine surgery, and primary elective CS were analyzed between the two groups. Results： The rate of primary elective CS （90.1% vs. 69.9%, P 〈 0.001 ） was higher, and maternal age was younger （32.7 ± 4.7 years vs. 34.6 ± 4.0 years, P 〈 0.001） in case group, compared with control group. Case group also had higher gravity and induced abortions compared with the control group （both P 〈 0.05）. Primary CS without labor was associated with significantly increased risk of placenta accreta in a subsequent pregnancy complicated with placenta previa （odds ratio： 3.32; 95% confidential interval： 1.68-6.58）. Conclusion： Women with a primary elective CS without labor have a higher chance of developing an accreta in a subsequent pregnancy that is complicated with placenta previa.

B-Lynch缝合术与改良Hwu缝合术在前置胎盘剖宫产术中的应用效果比较

目的对比B-Lynch缝合术与改良Hwu缝合术在前置胎盘剖宫产术中的应用效果。方法将60例前置胎盘剖宫产产妇根据子宫缝合技术不同分为B-Lynch组(n=30)和Hwu组(n=30)。B-Lynch组采用B-Lynch缝合术止血,Hwu组采用改良Hwu缝合术止血。比较两组的手术相关指标、预后指标及并发症发生情况。结果Hwu组手术时间、止血时间短于BLynch组,术中出血量少于B-Lynch组(P<0.05)。Hwu组恶露持续时间、首次月经恢复时间及月经周期短于B-Lynch组(P<0.05)。Hwu组并发症发生率为6.67%,与B-Lynch组的13.33%比较无统计学差异(P>0.05)。结论与B-Lynch缝合术相比,改良Hwu缝合术在前置胎盘剖宫产术中应用效果更佳,可明显缩短手术时间、止血时间,减少术中出血量,促进产妇预后恢复。

新型子宫下段平行垂直压迫缝合术联合麦角新碱治疗前置胎盘剖宫产产后出血的效果

目的 分析新型子宫下段平行垂直压迫缝合术联合麦角新碱治疗前置胎盘剖宫产产后出血的效果。方法 选择我院2017年1月至2021年12月收治的40例前置胎盘剖宫产产后出血患者作为研究对象,以随机法将其分为常规组(20例,新型子宫下段平行垂直压迫缝合术治疗)和观察组(20例,新型子宫下段平行垂直压迫缝合术联合麦角新碱治疗)。比较两组的治疗效果。结果 观察组的红细胞悬液用量、血浆用量、止血时间、住院时长及治疗后2、24 h的出血量均低于常规组(P<0.05)。观察组的不良事件总发生率低于常规组(P<0.05)。治疗后,观察组的活性氧(ROS)、丙二醛(MDA)及D-二聚体(D-D)水平显著低于常规组,超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)及过氧化氢酶(CAT)水平显著高于常规组,凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)显著短于常规组(P<0.05)。治疗后,观察组的子宫螺旋动脉收缩期峰值流速(PSV)、搏动指数(PI)均显著高于常规组,阻力指数(RI)显著低于常规组(P<0.05)。结论 新型子宫下段平行垂直压迫缝合术联合麦角新碱治疗前置胎盘剖宫产产后出血可取得理想的效果。

围术期手术室综合保温干预对前置胎盘剖宫产产妇术后的短期影响

目的:分析围术期手术室综合保温干预对前置胎盘剖宫产产妇术后短期影响。方法:选取2020年1月-2023年12月本院收治拟行剖宫产的前置胎盘孕产妇82例,采用随机数字表法分为对照组(41例,接受常规护理干预)和观察组(41例,接受围术期手术室综合保温干预)。比较两组产妇体温变化、手术相关指标、内稳态情况,采用床边颤抖评估量表(BSAS)量表颤抖情况,低温寒战发生情况采用纽卡斯尔护理满意度量表(NSNS)评估护理满意度。结果:围术期干预后,观察组产妇(麻醉起效后)T1、(胎儿分娩后)T2、(手术结束时)T3时体温(36.62±0.33℃、36.55±0.26℃、36.50±0.41℃)均高于对照组(35.71±0.29℃、35.37±0.29℃、35.31±0.35℃),T3时的血糖(7.52±1.50 mmol/L)、血乳酸(1.44±0.51 mmol/L)水平均低于对照组(8.65±1.75 mmol/L、1.87±0.39 mmol/L),pH值(7.35±0.04)高于对照组(7.30±0.05),产妇术中失血量(481.4±35.7ml)、麻醉苏醒时间(56.4±6.2 min)均低于对照组(691.6±51.8ml、75.4±5.4 min),血氧饱和度(97.7±1.2)%高于对照组(94.7±1.4)%,产妇BSAS评分(1.54±0.28分)低于对照组(2.01±0.37分),产妇低温寒战发生率(4.9%)及严重程度低于对照组(22.0%),产妇护理满意度(97.6%)高于对照组(82.9%)(均P<0.05)。结论:剖宫产围术期手术室综合保温干预可有效保持前置胎盘孕产妇体温恒定,减少术中失血及麻醉苏醒时间,有助于血氧维持,有利于维持内稳态,减少产妇颤抖、寒战发生,产妇满意度较高。

髂内动脉球囊预置阻断术在植入型凶险性前置胎盘中的临床研究

目的:探讨髂内动脉球囊预置阻断术在植入型凶险性前置胎盘中的临床价值。方法:选取2021年7月—2024年1月阳江市人民医院收治的60例植入型凶险性前置胎盘患者。根据随机数表法将其分为对照组与观察组,各30例。两组均行剖宫产,对照组应用常规止血措施,观察组应用双侧髂内动脉球囊预置术。比较两组围手术期指标、新生儿情况、子宫切除率、并发症。结果:观察组术中出血量少于对照组,手术时间与住院时间均短于对照组,差异有统计学意义(P<0.05)。两组新生儿出生1 min、5 min、10 min Apgar评分比较,差异无统计学意义(P>0.05)。观察组子宫切除率、并发症发生率均低于对照组,差异有统计学意义(P<0.05)。结论:双侧髂内动脉球囊预置术应用于植入型凶险性前置胎盘患者中效果显著,能够减少产妇术中出血量,降低大出血风险,缩短手术时间和住院时间,降低患者子宫切除率与术后并发症发生率。

护理团队结合血液加温仪在凶险性前置胎盘剖宫产术患者中的应用研究

目的:探讨护理团队结合血液加温仪在凶险性前置胎盘(PPP)剖宫产术患者中的应用价值。方法:选择2020年6月至2022年6月收治的PPP患者82例,按随机数字表法分为对照组和观察组各41例。对照组采用常规护理;观察组采用护理团队结合血液加温仪护理。对比分析两组围术期相关指标、体温变化情况、护理满意度和并发症。结果:观察组手术时间(59.20±4.46)min、住院时间(6.02±1.27)d,短于对照组的(68.42±5.13)min、(7.85±1.34)d;术中出血量(448.38±24.73)mL,低于对照组的(472.63±29.52)mL;且术后体温(36.61±0.14)℃、护理满意度95.12%,高于对照组的(36.31±0.12)℃、78.05%;术后并发症发生率为4.88%,低于对照组的19.51%,差异有统计学意义(P<0.05)。结论:护理团队结合血液加温仪能够有效促进PPP患者剖宫产术顺利实施,且具有术中出血量少、并发症少、减少体温波动的优势,可促使患者尽早出院,且护理满意度较高。