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An Improved Coupled Level Set and Continuous Moment-of-Fluid Method for Simulating Multiphase Flows with Phase Change
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作者 Zhouteng Ye Cody Estebe +8 位作者 Yang Liu Mehdi Vahab Zeyu Huang Mark Sussman Alireza Moradikazerouni Kourosh Shoele Yongsheng Lian Mitsuhiro Ohta M.Yousuff Hussaini 《Communications on Applied Mathematics and Computation》 EI 2024年第2期1034-1069,共36页
An improved algorithm for computing multiphase flows is presented in which the multimaterial Moment-of-Fluid(MOF)algorithm for multiphase flows,initially described by Li et al.(2015),is enhanced addressing existing MO... An improved algorithm for computing multiphase flows is presented in which the multimaterial Moment-of-Fluid(MOF)algorithm for multiphase flows,initially described by Li et al.(2015),is enhanced addressing existing MOF difficulties in computing solutions to problems in which surface tension forces are crucial for understanding salient flow mechanisms.The Continuous MOF(CMOF)method is motivated in this article.The CMOF reconstruction method inherently removes the"checkerboard instability"that persists when using the MOF method on surface tension driven multiphase(multimaterial)flows.The CMOF reconstruction algorithm is accelerated by coupling the CMOF method to the level set method and coupling the CMOF method to a decision tree machine learning(ML)algorithm.Multiphase flow examples are shown in the two-dimensional(2D),three-dimensional(3D)axisymmetric"RZ",and 3D coordinate systems.Examples include two material and three material multiphase flows:bubble formation,the impingement of a liquid jet on a gas bubble in a cryogenic fuel tank,freezing,and liquid lens dynamics. 展开更多
关键词 Moment-of-Fluid(MOF) surface tension Two phase flow Phase change Deforming boundaries with change(s)in topology Two-dimensional(2D) Three-dimensional(3D)axisymmetric 3D
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A Systematic Literature Review of the Impact of Climate Change on Menopause: Altering the Age, Severity of Symptoms and Long-Term Effects
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作者 Vaidehi Chauhan Sameena Rahman 《Open Journal of Obstetrics and Gynecology》 2024年第7期1018-1026,共9页
Objective: This systematic review investigates the impact of climate change on menopause, focusing on the correlation between geographical location—considering altitude, temperature, humidity, and annual temperature ... Objective: This systematic review investigates the impact of climate change on menopause, focusing on the correlation between geographical location—considering altitude, temperature, humidity, and annual temperature range—and women’s menopausal experiences. This study aims to interpret how these environmental factors influence the age of onset, severity of symptoms such as hot flushes and night sweats, and other long-term effects of menopause. Understanding these relationships addresses a significant gap in current knowledge and could guide future public health strategies. Methods: Through a comprehensive analysis of three cross-continental studies involving 1500 postmenopausal women from Spain, South American countries (Ecuador, Panama, Chile), various climates in Türkiye (Black Sea, Mediterranean, Continental), and the United Arab Emirates (UAE), this review evaluates diverse environmental impacts. Studies were selected based on their methodological rigor, geographical diversity, and focus on the unique and personal experiences of menopause. Data was collected via questionnaires and routine medical checkups, analyzing demographic, lifestyle, mood, symptom severity, and onset age variables. Results: Preliminary analysis indicates that 52.5% of participants from Spanish-speaking countries and the UAE reported vasomotor symptoms, with those in higher temperatures and lower altitudes experiencing exacerbated symptoms. Notably, Mediterranean climates were associated with an earlier menopause onset. Seasonal changes had minimal impact across all regions, suggesting lifestyle and other environmental factors play a more significant role. Conclusions: The findings highlight a clear link between climate-related geographical factors and the menopausal experience. Women in warmer, lower-altitude regions suffer more severe symptoms, while those in Mediterranean climates face earlier onset. The absence of significant seasonal variations across the studies underscores the predominance of lifestyle and environmental factors over purely climatic conditions. These insights pave the way for targeted interventions and support the need for further public health research into the complex interactions between climate change and menopause. 展开更多
关键词 MENOPAUsE Climate change Women’s Health PERIMENOPAUsE
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S型异质结光催化剂ZnFe_(2)O_(4)/WO_(3)的构筑及光催化还原CO_(2)性能
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作者 刘平 朱成才 +1 位作者 李艳阳 要红昌 《无机化学学报》 SCIE CSCD 北大核心 2024年第1期197-208,共12页
通过在WO_(3)纳米片表面负载ZnFe_(2)O_(4)纳米颗粒,构建了一系列S型异质结光催化剂ZnFe_(2)O_(4)/WO_(3),并研究了其光催化CO_(2)还原性能。在没有助催化剂和牺牲剂的条件下,所制备的ZnFe_(2)O_(4)/WO_(3)复合材料可对CO_(2)与水蒸汽... 通过在WO_(3)纳米片表面负载ZnFe_(2)O_(4)纳米颗粒,构建了一系列S型异质结光催化剂ZnFe_(2)O_(4)/WO_(3),并研究了其光催化CO_(2)还原性能。在没有助催化剂和牺牲剂的条件下,所制备的ZnFe_(2)O_(4)/WO_(3)复合材料可对CO_(2)与水蒸汽进行光催化反应。优化后的材料光照5 h后CO_(2)还原产物CO和CH_(4)的产量分别为7.87和4.88μmol·g^(-1)。相对于单相组分,CO和CH_(4)的产量明显提高。光催化活性的提高,归因于ZnFe_(2)O_(4)和WO_(3)异质结的形成以及光生载流子的S型电荷传输模式。 展开更多
关键词 CO_(2)还原 光催化活性 ZnFe_(2)O_(4)/WO_(3) 异质结 s型电荷传输模式
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Identifying the Cultural Shifts and Societal Changes That Facilitated the Rise in Box Office Performance of Chinese Women’s Cinema in the 21st Century
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作者 CUI Yuekun 《Psychology Research》 2023年第12期577-599,共23页
With the gradual improvement of Chinese women’s status in the 21st century,gender studies and gender relations have become one of the hottest topics in Chinese society,which consequently prompted Chinese Women’s Cin... With the gradual improvement of Chinese women’s status in the 21st century,gender studies and gender relations have become one of the hottest topics in Chinese society,which consequently prompted Chinese Women’s Cinema to attract the attention of larger audiences.With regard to the box office performance of Chinese Women’s Cinema,there seems to be a gap in research in finding an association between women’s status and the relevant films’box office performance.The purpose of this research is to outline the underlying reasons for the changes in gender roles and gender representation in the Chinese film industry over the past few decades in order to better understand this expansive social change in the 21st century.This study provides a comprehensive analysis through the use of questionnaires to better understand society’s attitude towards gender representation within the film industry.The questionnaire findings indicate that there is a direct correlation between people’s awareness of women’s changing status and gender equality and their acceptance of materials produced by Chinese Women’s Cinema.At the some time,it highlights that the Chinese government’s support and initiatives for gender equality have had a significant impact on the general popularity of Chinese Women’s Cinema.The significance of this research is to effectively popularize Chinese Women’s Cinema culture and the box office growth by understanding the social attitude towards gender representation in the Chinese film industry and to provide relevant information about the development direction and trend of Chinese Women’s Cinema.Furthermore,this research aims to provide foundational support for gender equality and help to understand the underlying factors that society needs to promote gender equality. 展开更多
关键词 Chinese Women’s Cinema Film Box Office Gender Equality social change Cultural shifts
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东北地区土地覆被格局变化模拟:基于CLUE-S和Markov-CA模型的对比分析
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作者 王端睿 毛德华 +2 位作者 王宗明 相恒星 冯凯东 《地理科学》 CSCD 北大核心 2024年第2期329-339,共11页
研究以遥感解译的东北地区2000年、2010年、2015年的土地覆被变化为基础,充分考虑自然和社会因素对土地覆被变化的影响,分别通过CLUE-S模型和Markov-CA模型对东北地区2015年和2030年土地覆被格局进行模拟,研究结果表明:通过与遥感解译的... 研究以遥感解译的东北地区2000年、2010年、2015年的土地覆被变化为基础,充分考虑自然和社会因素对土地覆被变化的影响,分别通过CLUE-S模型和Markov-CA模型对东北地区2015年和2030年土地覆被格局进行模拟,研究结果表明:通过与遥感解译的2015年实际土地覆被类型数据对比验证,CLUE-S模型和Markov-CA模型模拟结果的总体Kappa指数分别为0.9700和0.9649,结果表明2种模型的模拟结果较为理想,CLUE-S模型的模拟精度较Markov-CA模型更高。2015—2030年东北地区草地、耕地、湿地、其他用地和水体面积呈现下降趋势,林地、人工表面面积呈现增加趋势,人地关系越发紧张。东北地区作为生态环境相对脆弱的区域需警惕不可持续的土地覆被变化,需权衡生态保护、粮食增加与基础设施建设的用地需求和协调发展。 展开更多
关键词 CLUE-s模型 Markov-CA模型 土地利用/覆被变化 空间模拟 东北地区
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Changes in Rainfall and Temperature and Its Impact on Crop Production in Moyamba District, Southern Sierra Leone
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作者 Keiwoma Mark Yila Mathew Lamrana Siaffa Gboku +1 位作者 Mohamed Sahr Lebbie Lamin Ibrahim Kamara 《Atmospheric and Climate Sciences》 CAS 2023年第1期19-43,共25页
Rainfall and temperature are the important variables that are often used to trace climate variability and change. A Perception study and analysis of climatic data were conducted to assess the changes in rainfall and t... Rainfall and temperature are the important variables that are often used to trace climate variability and change. A Perception study and analysis of climatic data were conducted to assess the changes in rainfall and temperature and their impact on crop production in Moyamba district, Sierra Leone. For the perception study, 400 farmers were randomly selected from Farmer-Based Organizations (FBOs) in 4 chiefdoms and 30 Agricultural Extension Workers (AWEs) in the Moyamba district were purposely selected as respondents. Descriptive statistics and Kendall’s test of concordance was used to analyze the data collected from the farmers and AEWs. Data for the analysis of variability and trends of rainfall and temperature from 1991 to 2020 were obtained from the Sierra Leone Meteorological Agency and Njala University and grouped into monthly, seasonal and annual time series. Regression analyses were used to determine the statistical values and trend lines for the seasonal and annual time series data. The Mann-Kendall test and Sen’s Slope Estimator were used to analyze the significance and magnitude of the trends respectively. The results of both studies show evidence of climate change in the Moyamba district. A substantial number of farmers and AEWs perceived a decrease in the annual rainfall amount, length of the rainy season, a late start and end of the rainy season, an increase in the temperature during the day and night, and a shortened harmattan period over the last 30 years. Analysis of the meteorological data shows evidence of variability in the seasonal and annual distribution of rainfall and temperature, a decreasing and non-significant trend in the rainy season and annual rainfall and an increasing and significant trend in seasonal and annual temperature from 1991 to 2020. However, the observed changes in rainfall and temperature by the farmers and AEWs partially agree with the results of the analyzed meteorological data. The majority of the farmers perceived that;adverse weather conditions have negatively affected crop production in the district. Droughts, high temperatures, and irregular rainfall are the three major adverse weather events that farmers perceived to have contributed to a substantial loss in the yields of the major crops cultivated in the district. In response to the negative effects of adverse weather events, a substantial number of farmers take no action due to their lack of knowledge, technical or financial capacity to implement climate-sensitive agricultural (CSA) practices. Even though few farmers are practicing some CSA practices on their farms, there is an urgent need to build the capacity of farmers and AEWs to adapt to and mitigate the negative impacts of climate change. The most priority support needed by farmers is the provision of climate-resilient crop varieties whilst the AEWs need training on CSA practices. 展开更多
关键词 Climate change RAINFALL Temperature Farmer’s Perception Crop Productivity sierra Leone
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SAMP8小鼠在中医药抗痴呆中的应用研究进展
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作者 吴国庆 高誉珊 +1 位作者 汪子栋 李志刚 《世界科学技术-中医药现代化》 CSCD 北大核心 2024年第4期886-894,共9页
快速老化小鼠是一种早期学习记忆障碍模型,因其表现出阿尔茨海默病发病机制的大多数特征,包括抗衰老因子的异常表达、炎症因子的过度升高、淀粉样蛋白沉积、tau蛋白过度磷酸化、线粒体自噬、血脑屏障损伤的中枢机制以及多系统多器官的... 快速老化小鼠是一种早期学习记忆障碍模型,因其表现出阿尔茨海默病发病机制的大多数特征,包括抗衰老因子的异常表达、炎症因子的过度升高、淀粉样蛋白沉积、tau蛋白过度磷酸化、线粒体自噬、血脑屏障损伤的中枢机制以及多系统多器官的病理损伤,因而成为阿尔茨海默病(Alzheimer's disease,AD)研究的理想模型而广泛应用。随着AD机制实验研究的不断深入,发现SAMP8小鼠在行为活动、组织病理及生化参数指标上相较于SAMR1发生明显变化,并与人体疾病相类似。基于此,本文对SAMP8小鼠的行为学、组织病理和中医药实验研究进行了系统综述,加深对SAMP8小鼠的认识,了解其生理病理特性,并依据中医药实验研究对其中医证型进行推测,以期对SAMP8小鼠的科学应用提供有益帮助。 展开更多
关键词 快速老化小鼠 行为学 病理变化 阿尔茨海默病 综述
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联合GNSS与GRACE/GRACE-FO数据反演中国西南地区陆地水储量变化
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作者 杨兴海 袁林果 +1 位作者 姜中山 汤苗 《测绘学报》 EI CSCD 北大核心 2024年第5期813-822,共10页
GNSS和重力恢复与气候试验(GRACE)及其后续任务(GRACE-FO)给陆地水储量变化(TWSC)研究带来了技术革新,但这两种技术估计的区域TWSC具有不同的时空尺度和精度特性。因此,有必要融合两种观测数据,以获得同一尺度且高精度的TWSC。本文基于G... GNSS和重力恢复与气候试验(GRACE)及其后续任务(GRACE-FO)给陆地水储量变化(TWSC)研究带来了技术革新,但这两种技术估计的区域TWSC具有不同的时空尺度和精度特性。因此,有必要融合两种观测数据,以获得同一尺度且高精度的TWSC。本文基于GNSS独立反演模型,使用求和算子对喷气推进实验室(JPL)的GRACE/GRACE-FO Mascon数据进行求和运算来构建约束,通过赤池贝叶斯准则选择最优模型参数,构建了一种联合GNSS与GRACE/GRACE-FO数据的区域TWSC反演模型。随后,本文设计数值模拟试验,以验证利用该模型反演中国西南地区TWSC的可行性。结果显示,1000次试验中联合反演估算的均方根误差均值为10 mm,比GNSS独立反演结果低47%。基于此方法,本文联合GNSS与JPL Mascon数据反演了中国西南地区2011年1月—2022年6月的时变TWSC。对比联合反演、GNSS独立反演、GRACE/GRACE-FO和高分辨率全球陆地数据同化系统(GLDAS)的结果,发现联合反演与GLDAS的TWSC周年振幅空间分布特征最吻合,表明联合反演估计的TWSC空间分辨率优于GNSS独立反演和GRACE的结果。最后,结合水平衡方程估算的区域水文收支情况,并通过广义三角帽方法评估陆地水储量等效水柱高的变化率(d(EWH)/d t)的不确定性。结果显示,联合反演估计的d(EWH)/d t不确定性为8 mm/月,较GRACE/GRACE-FO、GNSS独立反演和水平衡方程结果分别低33%、68%和62%。研究结果表明,与GNSS和GRACE/GRACE-FO独立反演方法相比,联合反演能够改善TWSC估值的精度,可为水资源管理决策及水文气候学研究提供更可靠的数据支撑。 展开更多
关键词 GNss GRACE/GRACE-FO 联合反演 陆地水储量变化 赤池贝叶斯准则
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Exploring Variability in Sea Level at a Tide Gauge Station through Control Charts
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作者 H.Bâkiİz 《Journal of Environmental & Earth Sciences》 CAS 2024年第1期11-18,共8页
Monitoring temporal changes in sea level is important in assessing coastal risk.Sea level anomalies at a tide gauge station,if kinematically conceived,include systematic variations such as trend,acceleration,periodic ... Monitoring temporal changes in sea level is important in assessing coastal risk.Sea level anomalies at a tide gauge station,if kinematically conceived,include systematic variations such as trend,acceleration,periodic oscillations,and random disturbances.Among them,the non-stationary nature of the random sea level variations of known or unknown origin at coastal regions has been long recognized by the sea level community.This study proposes the analyses of subgroups of random residual statistics of a rigorously formulated kinematic model solution of tide gauge variations using X-bar and S control charts.The approach is demonstrated using Key West,Florida tide gauge records.The mean and standard errors of 5-year-long subgroups of the residuals revealed that sea level changes at this location have been progressively intensifying from 1913 to the present.Increasing oscillations in sea level at this locality may be attributed partly to the thermal expansion of seawater with increasing temperatures causing larger buoyancy-related sea level fluctuations as well as the intensification of atmospheric events including wind patterns and the impact of changes in inverted barometer effects that will alter coastal risk assessments for the future. 展开更多
关键词 Climate change sea level variance X-bar s control charts
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2024年1月23日乌什M_(S)7.1地震前新疆地电优势方位角变化特征分析
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作者 刘海洋 饶文 +1 位作者 徐衍刚 艾萨·伊斯马伊力 《内陆地震》 2024年第2期182-193,共12页
通过对2024年1月23日乌什M_(S)7.1地震前新疆境内5个地电台站观测数据的回溯性分析,计算地震前各台站地电优势方位角,总结数据变化特征,发现地震前各台站地电优势方位角均出现了不同程度的异常变化,异常表现为分散、集中、偏转和跃变的... 通过对2024年1月23日乌什M_(S)7.1地震前新疆境内5个地电台站观测数据的回溯性分析,计算地震前各台站地电优势方位角,总结数据变化特征,发现地震前各台站地电优势方位角均出现了不同程度的异常变化,异常表现为分散、集中、偏转和跃变的特征。其中震中附近的乌什台、温泉台地电优势方位角异常在时间上具有准同步变化。地震前震中500 km范围内的乌什、温泉、和田台不仅存在不同方位间相关系数的准同步下降变化,而且极化方位也出现了相似的线性极化增强现象,且乌什、和田台优势方位角的异常变化均呈现出向主压应力集中现象,说明在乌什M_(S)7.1地震前乌什、温泉、和田台观测到的地电数据变化,同此次地震具有一定机理上的联系。 展开更多
关键词 乌什M_(s)7.1地震 地电场 优势方位角 变化特性 震源机制
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基于CLUE-S和Markov模型的土地利用变化模拟预测
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作者 吉雄娟 程文仕 《国土与自然资源研究》 2024年第6期17-21,共5页
土地利用变化过程是极其复杂的,主要是因为其在变化的过程中不仅仅是单一因素作用的结果,而是多种因素掺杂在一起形成的复杂过程。在经济快速发展的今天,一旦区域土地利用存在不合理的情况,极容易影响区域资源可持续利用以及和谐稳定的... 土地利用变化过程是极其复杂的,主要是因为其在变化的过程中不仅仅是单一因素作用的结果,而是多种因素掺杂在一起形成的复杂过程。在经济快速发展的今天,一旦区域土地利用存在不合理的情况,极容易影响区域资源可持续利用以及和谐稳定的状态,土地利用变化模拟预测可以改善土地利用结构、提高土地利用效率,帮助相关部门规划国土空间布局,缓解人地矛盾,实现自然资源可持续发展。本文是基于高分辨率遥感影像解译得到靖远县2期土地利用数据,并利用CLUE-S与Markov模型相结合的方法对靖远县未来土地利用变化从自然发展、耕地保护和生态安全三种情景进行预测。结果表明,(1)CLUE-S模型相对于小尺度的土地利用变化模拟预测的效果较好,精度较高。(2)建设用地在自然发展情景下的增加是最为显著的,在其他两种情景下受到限制因素后在减少,草地和耕地只有在自然发展情景下是减少,林地只在耕地保护情景下是减少,水域用地和未利用地都在自然发展情景下是增加的。(3)生态安全情景与耕地保护情景对未来土地利用变化的调控效果较好,林地、草地和耕地受到了更好的保护。研究表明,区域土地利用模拟预测可以更好地为土地利用规划编制提供参考。 展开更多
关键词 CLUE-s模型 MARKOV模型 土地利用变化 情景模拟
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Analysis of New Senior English for China Student’s Book 1
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作者 Xia Qian 《语言与文化研究》 2024年第4期128-132,共5页
This article will firstly discuss the context overview of English teaching and learning in China. Under thiscircumstance, a problematic element will be examined of the New Senior English for China Student’s Book 1 an... This article will firstly discuss the context overview of English teaching and learning in China. Under thiscircumstance, a problematic element will be examined of the New Senior English for China Student’s Book 1 and critical appraisal ofhow this element relates to other elements of curriculum development will be analyzed. The recommended changes and demonstrationmechanisms for evaluating the changes are put forward in the last two parts. 展开更多
关键词 New senior English for China student’s Book 1 Assessment Critical appraisal Curriculum development changEs
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Changing Trend and Mutation Analysis of Number of Fog and Haze Days in Baoji City during 1981-2013
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作者 Li Gaiping Zhou Qi Zhai Yaqian 《Meteorological and Environmental Research》 CAS 2016年第4期5-9,共5页
Based on data of number of fog and haze days in Baoji City from 1981 to 2013,the changing trends and mutation of number of fog and haze days in Baoji over the past 33 years were analyzed by using trend coefficient,ten... Based on data of number of fog and haze days in Baoji City from 1981 to 2013,the changing trends and mutation of number of fog and haze days in Baoji over the past 33 years were analyzed by using trend coefficient,tendency rate,linear regression analysis,anomaly percentage,Mann-Kendall mutation test and sliding t test.The results showed that during the 33 years,the number of fog and haze days in Baoji declined by 16.253d/10 a,and there was a cyclical turbulence every 6,15 or 28years.The frequency of fog and haze weather was the highest in winter,followed by spring and autumn,while it was the lowest in summer.According to the anomaly percentage of the number of fog and haze days in 12 months during 1981-2013,the anomaly percentage changed most greatly in July,followed by September,October,April,May,June,August,February and March,but it fluctuated less greatly in January.The number of fog and haze days from 1981 to 2013had obvious mutation trends in a single year and a single season,and mutation types are different. 展开更多
关键词 Number of fog and haze days changing features Mann-Kendall method sliding t test method Baoji China
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The Cultural Implication of Brick Carving Model Calligraphy in Shanxi Chang's Manor
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作者 潘冬梅 冯涛 《Journal of Landscape Research》 2009年第11期63-67,共5页
Focusing on the unique style of brick carving model calligraphy in Shanxi Chang's manor,this research analyses the content and feature of the different parts of brick carving,and discuses the presenting cultural d... Focusing on the unique style of brick carving model calligraphy in Shanxi Chang's manor,this research analyses the content and feature of the different parts of brick carving,and discuses the presenting cultural deposits.It reflects the deep Confucian culture of Shanxi Chang's manor,with the peculiar charming in culture and aesthetic value. 展开更多
关键词 The chang’s MANOR MODEL CALLIGRAPHY BRICK CARVING Chinese traditional culture
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2022年1月8日青海门源M_(S)6.9地震前重力场动态变化 被引量:3
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作者 赵云峰 祝意青 +3 位作者 隗寿春 刘芳 梁伟锋 孙和平 《地球物理学报》 SCIE EI CAS CSCD 北大核心 2023年第6期2337-2351,共15页
2022年1月8日青海门源M_(S)6.9地震前,中国地震局在青藏高原东北缘开展了多期流动重力观测,并观测到震中附近重力场随时间的变化.我们曾利用震中附近重力场变化信息在地震前对发震地点进行了较为准确的预测.本文综合利用地面绝对重力、... 2022年1月8日青海门源M_(S)6.9地震前,中国地震局在青藏高原东北缘开展了多期流动重力观测,并观测到震中附近重力场随时间的变化.我们曾利用震中附近重力场变化信息在地震前对发震地点进行了较为准确的预测.本文综合利用地面绝对重力、相对重力资料,对青藏高原东北缘2018—2021年间的重力观测数据进行整体处理,系统分析了区域重力场动态变化及其与门源M_(S)6.9地震发生的关系.结合地震剪切波分裂、地壳裂隙及饱和度研究成果,进一步研究了区域重力场变化的时空分布特征及其机理.结果表明:(1)门源M_(S)6.9地震前2年累积重力变化呈现出明显的四象限分布特征,震中位于重力变化的四象限中心零等值线附近;(2)地震前重力异常持续时间与震级的关系、地震剪切波分裂产生的慢波时间延迟持续时间与震级的关系显现一致性,这种一致性表明地下流体运移可能是地震前观测到的重力变化的主要成因;(3)本次震中东南侧的显著重力变化延伸到了冷龙岭断裂东段至海原断裂一带,后期仍需要关注该地区的地震危险性. 展开更多
关键词 门源M_(s)6.9地震 中期预测 重力变化 四象限分布 流体运移
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pHSP70P-EGFP真核表达载体的构建及其在人Chang's肝细胞中的表达
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作者 高峰 陈亚军 杨学文 《临床检验杂志》 CAS CSCD 北大核心 2011年第6期444-447,共4页
目的构建HSP70启动子与绿色荧光蛋白重组真核表达载体,并在人Chang's肝细胞表达,建立一种新的体外药物肝毒性早期预测细胞模型。方法提取人Chang's肝细胞基因组DNA,钓取HSP70启动子基因,构建重组载体,经脂质体转染人Chang'... 目的构建HSP70启动子与绿色荧光蛋白重组真核表达载体,并在人Chang's肝细胞表达,建立一种新的体外药物肝毒性早期预测细胞模型。方法提取人Chang's肝细胞基因组DNA,钓取HSP70启动子基因,构建重组载体,经脂质体转染人Chang's肝细胞,用G418筛选稳定转染细胞,用荧光显微镜观察绿色荧光表达情况,用实时荧光定量PCR检测EGFP基因表达量的变化。结果成功钓取HSP70启动子基因并导入真核表达载体pEGFP-N1;G418以300 ng/mL的终浓度筛选出稳定转染的单克隆细胞;荧光显微镜观察到肝毒性药物酮康唑刺激人Chang's肝细胞后,可诱导HSP70启动子调控增强型绿色荧光蛋白发出绿色荧光,药物刺激组EGFP mRNA相对表达量与正常对照组比较有统计学意义(t=-14.21,P<0.05)。结论成功构建HSP70启动子与绿色荧光蛋白共表达真核表达载体,获得稳定转染单克隆细胞,并证实HSP70在肝毒性药物刺激下的应激表达,为建立新的体外药物肝毒性早期预测细胞模型进行高通量筛选新药奠定了基础。 展开更多
关键词 热激蛋白 启动子 chang's肝细胞 基因重组
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三亚M_(S)4.2地震前后海南岛重力场变化及其小波多尺度分解
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作者 李盛 黄章荣 +2 位作者 胡久常 解晓静 贾伟 《大地测量与地球动力学》 CSCD 北大核心 2023年第9期945-949,979,共6页
利用海南岛流动重力测网2016~2022年共13期复测资料,分析研究区域差分重力场和累积重力场动态变化,并着重分析2019-08-20海南三亚M_(S)4.2地震前后海南岛西南地区重力场时空变化。结果表明,三亚M_(S)4.2地震震中附近地区在震前2 a和3 a... 利用海南岛流动重力测网2016~2022年共13期复测资料,分析研究区域差分重力场和累积重力场动态变化,并着重分析2019-08-20海南三亚M_(S)4.2地震前后海南岛西南地区重力场时空变化。结果表明,三亚M_(S)4.2地震震中附近地区在震前2 a和3 a出现重力场累积变化梯度带,梯度带的异常范围约60 km,重力场变化最大约为60μGal;三亚M_(S)4.2地震之后,震中附近地区重力场继续上升,至2020年下半年才开始协同下降,在下降过程中,发生以2021-08-08乐东MS3.2地震为最大地震的震群事件。对2016-09~2019-08海南岛累积重力场动态变化小波多尺度分解表明,海南岛西南地区重力场变化在3阶、4阶和5阶小波细节图中均出现异常。 展开更多
关键词 三亚M_(s)4.2地震 重力场变化 梯度带 小波多尺度分解
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Landuse/landcover changes in Zhangye oasis of Hexi Corridor 被引量:9
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作者 MENG Jijun,WU Xiuqin,LI Zhengguo(Department of Urban and Environmental Scien ce, Peking University, Laboratory of Analysis and Simulation of Earth Surface P rocesses, the Ministry of Education, Beijing 100871, China) 《Journal of Geographical Sciences》 SCIE CSCD 2003年第1期71-75,共5页
Taking two f alse color composite Landsat 5 TM (Thematic Mapper) images of band 4,3,2 taken in 1995 and 2000 as data resources, this paper carried out study on LUCC of Zhan gye oasis in recent five years by interpreta... Taking two f alse color composite Landsat 5 TM (Thematic Mapper) images of band 4,3,2 taken in 1995 and 2000 as data resources, this paper carried out study on LUCC of Zhan gye oasis in recent five years by interpretation according to land reso urces classification system of 1:100,000 Resources and Environmental Data base of the Chinese Academy of Sciences. The results show that great changes have taken place in landuse/landcover in Zhangye oasis since 1 995: (1) Changes of landuse structure show that cropland and land for urban c onstruction and built-up area increased, on the contrary, water area an d grassland decreased. These changes reflect the deterioration of eco-e nvironment and the acceleration of urbanization, and also indicate the problems existing in the arrangement of water and land resources betw een the upper and lower reaches of the Heihe River. (2) Regional diff erences of landuse/landcover are evident, characterized by following asp ects: in Sunan County located in Qilian Mountain area, unused land an d grassland decreased, but cropland and land for urban construction an d built-up area increased. In Minle and Shandan counties located in f oothills, unused land, water area and cropland decreased, but grassland and land for urban construction and built-up area increased. In Zhan gye City, Linze County and Gaotai County located in plain area of th e middle reaches of the Heihe River, unused land, water area and gra ssland decreased, while woodland, cropland and land for urban construction and built-up area increased. 展开更多
关键词 landuse/landcover changes (LUCC) Zhangye oasi s Hexi Corridor
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Relationships of climate change and tree ring of Betula ermanii tree line forest in Changbai Mountain 被引量:34
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作者 YU Da-pao GU Hui-yan +2 位作者 WANG Jian-dong WANG Qing-li DAI Li-min 《Journal of Forestry Research》 SCIE CAS CSCD 2005年第3期187-192,共6页
Based on the tree-ring growth characteristics of Erman's birch (Betula ermanii charm.) and the relationships between it and climatic )'actors at elevation of 1950m, the sensitivity of tree lines in Changbai Mount... Based on the tree-ring growth characteristics of Erman's birch (Betula ermanii charm.) and the relationships between it and climatic )'actors at elevation of 1950m, the sensitivity of tree lines in Changbai Mountain to climatic factors was assessed. The results indicated tree line forest in Changbai Mountain had an obvious sensitivity to climate factors. However, difference from other study sits is that the main climatic control factor on tree-ring growth was not current growth season temperatures, as might be expected, but previous winter and current March temperature. Although the precipitation in the region was quite abundant, the tree-ring growth was still significantly correlated with the precipitation during previous winter and current spring. Additionally, climatic factors which influenced the Erman's birch growth were not the yearly variables, but seasonal and monthly variables. Therefore, the reported increase in yearly mean temperature and total yearly precipitation since 1980s was not responded by sustained increase in ring widths in recent decades. 展开更多
关键词 Climatic change dendrochronology Erman's birch Tree line in changbai Mountain
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Global glaciations and atmospheric change at ca.2.3 Ga 被引量:18
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作者 Haoshu Tang Yanjing Chen 《Geoscience Frontiers》 SCIE CAS CSCD 2013年第5期583-596,共14页
This paper compiles lithostratigraphic and geochronological data obtained for the Palaeoproterozoic glacial diamictite-bearing successions,and thereby provides insights into understanding the geological processes caus... This paper compiles lithostratigraphic and geochronological data obtained for the Palaeoproterozoic glacial diamictite-bearing successions,and thereby provides insights into understanding the geological processes causing the Huronian Glaciation Event.The majority of evidence for appearances of this glaciation event can be related to the Kenorland supercontinent breakup,allied to significant atmospheric change,as well as blooms of biogeochemical oxygenic photosynthesis.In this paper,the Huronian Glaciation Event is constrained to have occurred synchronously during 2.29-2.25 Ga,accompanied by dramatic environmental changes characteristic of the Great Oxidation Event which includes the pre- 2.3 Ga hydrosphere oxidation and the post-2.3 Ga atmosphere oxygenation. 展开更多
关键词 Global glaciation Earth’s environmental change Great Oxidation Event LITHOsTRATIGRAPHY GEOCHRONOLOGY
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