Mechanism of traditional Chinese medicine in the treatment of psoriasis with depression:A review

Psoriasis is a kind of immune-mediated, chronic, inflammatory skin disease, which is often associated with different degrees of psychological disorders. Specifically, there is a significant correlation between psoriasis and depression, and they show the relationships of reciprocal causation and mutual promotion. Psoriasis with depression is more harmful than simple psoriasis, and its prognosis is worse, which brings a huge burden to the family and society and is worthy of clinical attention. Based on the pathogenic factors of western medicine and pathogenesis of traditional Chinese medicine in psoriasis with depression, the paper summarized and elaborated the research progress on the mechanism of traditional Chinese medicine in the treatment of psoriasis with depression, in order to provide new ideas for clinical treatment.

Application and Practice of Traditional Chinese Medicine Characteristic Technology Inheritance in Research and Development of Traditional Chinese Medicine Preparations in Medical Institutions

Medical institution preparations play an important role in the development of hospitals,being one of the main forms of traditional Chinese medicine clinical characteristic medication,as well as an important carrier for the inheritance and innovation of traditional Chinese medicine.In recent years,the research and development of traditional Chinese medicine preparations has become a hot spot in the research and development of preparations by medical institutions.Traditional Chinese medicine preparations prepared by traditional processes and their entrusted preparation matters have changed from the current licensing management to filing management.The registration model of traditional Chinese medicine preparations has undergone significant changes,emphasizing more on real data and evaluation results from the objective world,respecting traditional medication experience,and emphasizing the inheritance and innovative development of traditional technological experience.In the process of following teachers in the inheritance project of traditional Chinese medicine,we combined the inheritance of traditional Chinese medicine characteristic technology with the research and development practice of traditional Chinese medicine preparations in medical institutions,and focused on the analysis and discussion of technical problems such as prescription screening,dosage form selection,process route design and clinical observation of traditional Chinese medicine preparations,hoping to provide reference for scholars in the same field of traditional Chinese medicine.

Through a Century: Traditional Chinese Medicine Since 1912

Since 1912,traditional Chinese medicine(TCM)went through the stages of the struggle,foundation,and growth.The all-round developing TCM is academically progressing and promoted worldwide.Characteristics of the centennial development of TCM have cultural relevance,policy pertinency,mutual supplement between Chinese and western medicine and TCM is treatment directed by pattern diagnosis.Researches show that the historical inevitable development of TCM will benefit the people for generations to come when taken as a national strategy.

Unique Traditional Chinese Medicine Therapy for Painful Diabetic Peripheral Neuropathy

Painful diabetic peripheral neuropathy is one of the common chronic complications of diabetes."Pain"is the most typical symptom in patients,which seriously affects their quality of life.Traditional Chinese medicine(TCM)treatment of the disease includes oral administration of Chinese medicine,TCM fumigation and acupuncture,etc.,which can significantly reduce the pain of patients and reduce the frequency of disease.Chinese decoctions regulate the imbalance of yin and yang in the human body through syndrome differentiation,so as to achieve the balance of yin and yang,which will then eliminate the disease.Chinese medicine fumigation make the medicine seep into the body from the skin to exert the medical effects,and nourish and dredge the meridians.There is no pain if the meridians are smooth flowing,there will be pain if the meridians are blocked,fumigation can be used alone or assisted by other treatment methods to enhance the efficacy.The characteristics of acupuncture are rapid painrelief,economic and convenient,and can quickly relieve pain for patients with low tolerance.

Comparison of intestinal absorption characteristics between rhubarb traditional Chinese medicine preparation and activity ingredients using in situ and in vitro model

Objective: The intestinal absorption characteristics of active ingredients are very important for oral administration of traditional Chinese medicine(TCM) to achieve the desired therapeutic effect.However, a deeper understanding about active ingredients absorption characteristics is still lack. The aim of this study was to investigate the absorption properties and mechanism of rhubarb active ingredients in TCM preparation and pure form.Methods: The intestinal absorption behavior of active ingredients in Shenkang extract(SKE) and rhubarb anthraquinone ingredients(RAI) were investigated by in situ single-pass intestinal perfusion model. And the bidirectional transport characteristics of these active ingredients were assessed by in vitro Caco-2 cell monolayer model.Results: In situ experiment on Sprague-Dawley rats, the effective permeability coefficient values of aloeemodin, emodin and chrysophanol in RAI were higher than those in SKE, and the value of rhein in RAI was lower than that in SKE. But the easily absorbed segments of intestine were consistent for all ingredients,whether in SKE or in RAI. In vitro experiment, the apparent permeability coefficient values of rhein, emodin and chrysophanol in RAI were higher than those in SKE, and this value of aloe-emodin in RAI was lower than that in SKE. But their efflux ratio(ER) values in SKE and RAI were all similar.Conclusion: Four rhubarb anthraquinone ingredients in SKE and RAI have similar absorption mechanism and different absorption behavior, and the microenvironment of the study models influenced their absorption behavior. The results may provide an aid for understanding of the absorption characteristics of the TCM active ingredients in complex environments and the complementarities of different research models.

Multifactor dimensionality reduction analysis of syndrome characteristics of chronic persistent asthma

Objective:To analyze the syndrome characteristics in patients with chronic persistent asthma.Methods:365 patients(121 males,244 females,60.829.1 years old)with chronic persistent asthma were enrolled in this cross-sectional study.The information of syndrome,symptoms,signs,tongue coating and pulse were collected from all patients.The syndrome characteristics of chronic persistent asthma were examined through the multifactor dimensionality reduction(MDR)analysis and the results were verified by the Chi-square test.Results:The results of the MDR analysis and the Chi-square test showed the following positive correlation of the interaction among:the deficiency syndrome of the lung and spleen and deep pulse,disinclination to talk due to lack of qi,fatigue,lassitude and thick tongue coating;the deficiency syndrome of the lung and kidney and dizziness and disinclination to talk due to lack of qi,fatigue,lassitude and pallid complexion;the syndrome of phlegm-heat obstructing the lung and rapid pulse,abdominal distension,disinclination to talk due to lack of qi,frequent urination and lassitude;the syndrome of phlegm-dampness obstructing the lung and disinclination to talk due to lack of qi,greasy coating,fatigue and lassitude.(P<.05 for all).Conclusion:The syndrome of chronic persistent asthma is characterized by fatigue and lassitude due to dysfunction of the lung,spleen and kidney.

岭南中医妇科课程标准化教学改革

地域特色课程是中医药院校的新兴课程,是我国发展中医药事业和高等中医药教育教学改革的重要组成部分,课程质量是培育人才的基石。文章基于岭南中医妇科课程标准化建设研究,通过分析目前的中医人才的培育要求及中医院校课程标准化的现状,指出该课程教学改革的必要性,从教材编写、教学设计、教学比例、教师队伍、教学形式、教学方法及考评方式等方面提出思考及实践总结,强调思政立德树人,跟师守正创新。以期为同类课程设置及教学实践提供参考。

湖湘古代中医药文献的类型与特点述略

湖湘中医药文献既是湖湘先人认识疾病的重要途径,又是湖湘地区中医药知识的重要宝库。从早期的口头传承到简帛、竹木简牍,再到纸质文献,湖湘中医药文献呈现了丰富多样的类型和独特的发展轨迹。周秦两汉时期,湖湘中医药文献开始萌芽,主要以简帛文献为主;魏晋隋唐时期,文献载体逐渐向竹木简牍转变,且养生文献得到发展;宋金元时期,方书集合文献占据主导地位,中医药知识体系更趋完善;明清时期,见证了湖湘中医药文献的鼎盛,特别是处理时疫的文献得到广泛流传。通过厘清湖湘古代中医药文献的类型与特点,展示和挖掘湖湘中医药知识和理论的构建历程,从而促进湖湘中医药及其文献的研究利用。

中医治疗银屑病伴抑郁症的机制研究进展

银屑病是由免疫介导的慢性、炎症性皮肤病,常伴不同程度的心理障碍,其中,银屑病与抑郁症具有显著的关联性,呈现互为因果、互相促进的紧密关系。银屑病伴抑郁症较单纯银屑病危害更大,预后更差,给家庭及社会带来巨大负担,值得临床关注。本文基于银屑病伴抑郁症的西医发病因素及中医病机认识,总结阐述中医治疗银屑病抑郁机制的研究进展,以期为临床诊疗提供新的思路。

《中华中医药学刊》刊文特征与热点分析

目的 系统总结和分析《中华中医药学刊》2007—2022年所刊文的内容特征与热点,以期为《中华中医药学刊》的发展提供参考。方法 综合运用CiteSpace、VOSviewer等文献计量工具,从刊文量、研究者、研究机构、刊文主要关键词、刊文热点主题、刊文研究趋势等,进行多维视角的可视化分析。结果 年刊文数量呈下降趋势,但刊文质量显著提升;研究者之间连线较为密集;研究者群体相对稳定。结论 刊文研究者合作关系相对紧密;呈现以高校及其附属医院为核心研究者群体特征;中西医结合、中药现代化和针灸治疗现代化三大主题,是《中华中医药学刊》2007—2022年的研究热点。

浅析天津中药炮制技术的形成、发展与特色

天津中药饮片炮制起源于明代,成于清代,独具地方特色。为了传承与发扬天津中药炮制特色,文章通过整理文献书籍和《天津中药饮片炮制规范》2022版,分析了天津中药炮制技术的形成、发展与特色。天津中药炮制优选道地药材;修治与软化药材技术多样;切制技术兼容并蓄;辅料使用丰富多彩,重用醋与黄酒,善用甘草水炮制解毒;炮炙技术丰富,醋煮技术独具特色,通过比较《中国药典》2020版与其他地方中药材与饮片标准,挖掘出一些特色炮制品种。经过本文的挖掘与分析,可以为天津中药炮制的继承、发展与推广提供参考。

中医特色康复联合核心肌群训练在椎间盘源性腰痛中的应用

目的探讨中医特色康复联合核心肌群训练治疗椎间盘源性腰痛(DLBP)的效果及对患者腰椎功能、多裂肌横截面积、腰大肌横截面积的影响。方法选取2018年5月至2020年6月收治的180例DLBP患者作为研究对象,采用随机数字表法分为3组,每组60例。中医组用中医特色康复治疗,训练组用核心肌群训练,联合组加用中医特色康复联合核心肌群训练,均于治疗8周后进行疗效观察。统计对比3组疗效、视觉模拟评分法(VAS)、功能障碍指数问卷表(ODI)评分、Rdand Morris问卷(RMQ)、多裂肌横截面积、腰大肌横截面积。结果联合组治疗8周后总有效率(100.00%)高于中医组(81.67%)、训练组(85.00%),差异有统计学意义(P<0.05);联合组治疗4、8周后VAS评分、ODI评分低于中医组、训练组,差异有统计学意义(P<0.05);联合组治疗4、8周后多裂肌横截面积、腰大肌横截面积及RMQ评分高于中医组、训练组,差异有统计学意义(P<0.05);中医组、训练组各指标比较,差异无统计学意义(P>0.05)。结论中医特色康复联合核心肌群训练应用于DLBP患者中效果显著,能减轻疼痛,改善患者病情。

辨章学术守正本考镜源流求新知——南京中医药大学医史文献学科70年发展回溯与展望

南京中医药大学中医医史文献学科70年来经历了初创期(1954—1958)、成熟期(1959—1977)、发展期(1978—1999)和提升期(2000年至今)4个历史阶段。在一代代学科带头人和学术骨干呕心沥血的努力下,完成了多部具有里程碑意义的划时代中医药文献传世巨著,承担了多项国家级重大与重点项目。学科特色鲜明,以擅长整理编纂大型中医药工具书为成果标志,文献研究以注重实用性为导向,在研究领域以本草和方剂为工作重点,从而为现代临床、科研和教学提供有效信息。未来学科发展将在保持特色的基础上,充分利用新知识和新方法,开展中医药文献的信息化和数智化研究,培养更多优秀的高层次中医医史文献专业人才。

中医正骨学古今教学特点刍议

中医正骨学是一门技术性学科,在古今都占有着重要的医疗地位。文章针对中医正骨学的古代和现代教学特点进行讨论,并根据发展的实际情况分析教学模式的变化特点,以便更好地保持我国中医药治疗的特色和优势,使中医正骨学保持学科特色、发挥学科优势,充分利用现代科学技术,走在科技的前线,与现代高新技术相结合,促进其教学发展。

中医特色护理在痛风性关节炎中的应用研讨

目的针对痛风性关节炎(GA)患者在常规护理基础上联合中医特色护理,观察其对患者日常生活活动能力、生活质量的影响。方法收集2021年7月至2023年1月我院GA患者(n=60)进行前瞻性研究,采用随机数字表法将患者分为两组。对照组采用常规护理,内容包括生活起居、饮食、运动、心理、疼痛指导、穴位贴敷,观察组在此基础上联合耳部全息铜砭刮痧。比较两组护理前后Barthel评分、关节肿胀与疼痛程度(VAS量表),采用问卷调查患者满意度并进行比较。结果护理前组间Barthel、关节肿胀及疼痛评分比较结果为P>0.05;经过不同方案的护理之后,观察组Barthel评分高于对照组与护理前,关节肿胀、疼痛评分低于对照组与护理前,差异显著(P<0.05);观察组护理满意度为93.33%与对照组的73.33%比较,差异明显(P<0.05)。结论中医特色护理有利于改善GA患者临床症状,减轻关节肿胀及疼痛程度,提高患者日常生活活动能力,患者满意度高。

中西医结合康复对不完全性脊髓损伤的影响

目的探讨中西医结合康复对不完全性脊髓损伤(ISCI)患者的影响。方法选择64例不完全性脊髓损伤患者,采用随机数字表简单化分组法(余数法)分为观察组与对照组,各32例,对照组给予常规物理治疗+康复训练,观察组在对照组基础上联合针刺+中医特色功能训练。通过评估美国脊柱损伤学会运动评分(ASIA-MS)、疼痛视觉模拟评分(VAS)、日常生活能力评分(ADL)、10 m最快步行速度测试(10MWT)、6 min步行耐力测试(6MWT)、计时起立-行走测试(TUGT)、Berg平衡量表(BBS)变化情况,分析2组康复效果。结果康复治疗4周时,观察组ASIA-MS、ADL评分高于对照组(P<0.05),VAS评分低于对照组(P<0.05);治疗4周、6周、8周时,观察组10MWT均低于对照组(P<0.05),6MWT均高于对照组(P<0.05);观察组治疗8周时TUGT低于对照组(P<0.05);观察组治疗8周、12周时BBS评分高于对照组(P<0.05)。结论中西医结合康复治疗有利于不完全性脊髓损伤神经再生修复,促进患者步行能力、平衡能力提升。

赓续中华文脉书写中医文化创新发展新篇章——近40年来南京中医药大学中医文化学科发展的回顾与思考

南京中医药大学中医文化学40年的发展经历了早期的自由探索、中期的有组织科研和近期的重点学科快速发展3个阶段。我校中医文化学在学科构建、马克思主义理论同中医文化相结合研究、重大重点项目研究、文化育人等方面走在全国前列,发挥了示范引领作用。进入新的发展阶段,中医文化学要着力赓续中华文脉,在交叉团队建设上多出智慧,在“第二个结合”上多出成果,在“顶天立地”上多下功夫,在协同创新中推动学科高质量发展。

中西医协同防治慢性病的科学思路与方法

慢性病是临床上较为常见的疾病类型,具有发展隐匿、发病机制复杂、患者预后较差、临床治疗难度大等特点。中西医协同治疗对提高慢性病患者的生存质量、临床疗效有显著优势。随着社会的不断进步和人民对健康意识的不断提高,中西医协同治疗慢性病成为了当今卫生服务发展的主要方向。通过文献综述方法系统地整理了慢性病具有虚弱性、缠绵性和复杂性的发病特点,以络虚不荣、痰瘀阻络、久虚络瘀为其核心病机,同时提出了中西医协同全方位、全周期防治慢性病的科学思路与方法,旨在为慢性病防治工作提供更为全面、更科学的参考依据。

川派中药炮制技艺的历史源流与特色

川派中药炮制技术作为全国四大炮制流派之一,历来在中药炮制界占据十分重要的地位,是国家级非物质文化遗产。本研究通过对其发展源流进行考证,并总结其发展规律,完善对川派中药炮制的认识与研究,找出川派中药炮制的独到之处,推动川派中药炮制的保护传承与创新发展。

康复训练结合中医特色护理在缺血性脑卒中后肩手综合征患者中的应用效果

目的探讨康复训练结合中医特色护理在缺血性脑卒中后肩手综合征患者中的应用效果。方法回顾性选择2022年3月至2023年3月华中科技大学同济医学院附属同济医院收治的90例缺血性脑卒中后肩手综合征患者资料进行分析。根据护理方法的不同分为对照组与观察组,每组45例。其中对照组采用常规护理,观察组实施康复训练结合中医特色护理。比较2组患者的日常生活能力、上肢运动功能、手肿胀程度、手功能、疼痛程度及有效率。结果护理7 d及护理1个月后,观察组的改良Barthel指数、简氏Fugl-Meyer评定量表(FMA)上肢功能评分、简单手功能检查(STEF)得分均明显高于对照组,肿胀程度均轻于对照组(P均<0.05),且2组均优于护理前(P均<0.05)。护理1个月后,观察组屈曲、外展、外旋及内旋的疼痛视觉模拟量表(VAS)评分均低于对照组(P均<0.05),且2组均较护理前降低(P均<0.05)。观察组的总有效率高于对照组(P<0.05)。结论康复训练结合中医特色护理应用于缺血性脑卒中后肩手综合征患者的临床护理中,能够有效改善患者的上肢运动功能、手功能,减轻手肿胀程度和疼痛,提高其日常生活能力及有效率。