Varicella (chickenpox) is a generalized, self-limiting viral infection that is caused by varicella zoster virus (VZV). Chickenpox commonly infects children from 2 - 8 years without severe outcomes, but is particularly...Varicella (chickenpox) is a generalized, self-limiting viral infection that is caused by varicella zoster virus (VZV). Chickenpox commonly infects children from 2 - 8 years without severe outcomes, but is particularly severe when affecting adults.展开更多
A previously well 5-year-old boy presented with a 4-day his-tory of fever (39.2 °C) and spreading rash. His elder sister was diagnosed with a typical chickenpox two weeks ear-lier. The rash consisting of vesicles...A previously well 5-year-old boy presented with a 4-day his-tory of fever (39.2 °C) and spreading rash. His elder sister was diagnosed with a typical chickenpox two weeks ear-lier. The rash consisting of vesicles initially started on his head and spreaded to his body and limbs. On the third day of this illness, large erythematous maculopapular elements appeared on his left ear and lower legs and progressed into bullae 3–4 cm in diameter. Over the night, large eroded bul-lae were found on his inner thighs (Fig. 1a), body and upper limbs. Enzyme-linked immunosorbent essay performed on day 4 after the rash onset was positive for specific type 3 Varicella Zoster antibodies. Bacteriological examination of the bullae contents was negative. The patient was started on acyclovir. Healing of skin lesions occurred by day 11 of the disease (Fig. 1b). Bullous forms most frequently result from co-infection with S. pyogenes and S. aureus. (1)In the pre-sent case, no evidence of bacterial co-infection was found.展开更多
目的:对北京市怀柔区某小学一起水痘突发疫情进行流行病学分析,为今后更好的处理水痘暴发疫情提供流行病学依据。方法:收集中国疾病控制信息系统中北京市怀柔区某小学的一起水痘突发疫情个案病例和突发疫情信息,采用描述流行病学方法分...目的:对北京市怀柔区某小学一起水痘突发疫情进行流行病学分析,为今后更好的处理水痘暴发疫情提供流行病学依据。方法:收集中国疾病控制信息系统中北京市怀柔区某小学的一起水痘突发疫情个案病例和突发疫情信息,采用描述流行病学方法分析流行病学特征。结果:水痘发病年龄(6~12)岁,以一年级为主,共27例,占总病例数的67.50%;应急后免疫未超过1个月发病的2例,免疫史超过3年的发病3例,超过4年的发病3例,超过5年的发病25例,分别占5.88%、8.82%、8.82%、73.53%。结论:水痘易在学校等集体单位暴发流行,发病以低年级儿童为主,免疫史超过5年的突破病例较多。学校等集体单位在严格落实各项防控措施的同时,接种水痘减毒活疫苗(VaricellaAttenuated Live Vaccine;VarV)是预防和控制水痘最有效和最可靠的手段。展开更多
文摘Varicella (chickenpox) is a generalized, self-limiting viral infection that is caused by varicella zoster virus (VZV). Chickenpox commonly infects children from 2 - 8 years without severe outcomes, but is particularly severe when affecting adults.
文摘A previously well 5-year-old boy presented with a 4-day his-tory of fever (39.2 °C) and spreading rash. His elder sister was diagnosed with a typical chickenpox two weeks ear-lier. The rash consisting of vesicles initially started on his head and spreaded to his body and limbs. On the third day of this illness, large erythematous maculopapular elements appeared on his left ear and lower legs and progressed into bullae 3–4 cm in diameter. Over the night, large eroded bul-lae were found on his inner thighs (Fig. 1a), body and upper limbs. Enzyme-linked immunosorbent essay performed on day 4 after the rash onset was positive for specific type 3 Varicella Zoster antibodies. Bacteriological examination of the bullae contents was negative. The patient was started on acyclovir. Healing of skin lesions occurred by day 11 of the disease (Fig. 1b). Bullous forms most frequently result from co-infection with S. pyogenes and S. aureus. (1)In the pre-sent case, no evidence of bacterial co-infection was found.
文摘目的:对北京市怀柔区某小学一起水痘突发疫情进行流行病学分析,为今后更好的处理水痘暴发疫情提供流行病学依据。方法:收集中国疾病控制信息系统中北京市怀柔区某小学的一起水痘突发疫情个案病例和突发疫情信息,采用描述流行病学方法分析流行病学特征。结果:水痘发病年龄(6~12)岁,以一年级为主,共27例,占总病例数的67.50%;应急后免疫未超过1个月发病的2例,免疫史超过3年的发病3例,超过4年的发病3例,超过5年的发病25例,分别占5.88%、8.82%、8.82%、73.53%。结论:水痘易在学校等集体单位暴发流行,发病以低年级儿童为主,免疫史超过5年的突破病例较多。学校等集体单位在严格落实各项防控措施的同时,接种水痘减毒活疫苗(VaricellaAttenuated Live Vaccine;VarV)是预防和控制水痘最有效和最可靠的手段。