This article will firstly discuss the context overview of English teaching and learning in China. Under thiscircumstance, a problematic element will be examined of the New Senior English for China Student’s Book 1 an...This article will firstly discuss the context overview of English teaching and learning in China. Under thiscircumstance, a problematic element will be examined of the New Senior English for China Student’s Book 1 and critical appraisal ofhow this element relates to other elements of curriculum development will be analyzed. The recommended changes and demonstrationmechanisms for evaluating the changes are put forward in the last two parts.展开更多
Five stems of rapeseed with abundant black microsclerotia were collected from Huangyuan County of Qinghai Province,China,and fungal isolates were obtained from the stems.They were identified based on morphology,molecu...Five stems of rapeseed with abundant black microsclerotia were collected from Huangyuan County of Qinghai Province,China,and fungal isolates were obtained from the stems.They were identified based on morphology,molecular features and specific PCR detection.The results showed that the 10 fungal isolates belonged to Verticillium longisporum lineage A1/D3.One of the 10 isolates(HW7-1)was tested for virulence on three species of rapeseed,including B.napus Zhongshuang 9,B.rapa Qingyou 9 and B.juncea Tayou 2 by conidia inoculation of HW7-1 on roots of young seedlings.Control seedlings were inoculated with V.dahliae conidia or water alone.The seedlings of these treatments were transplanted in culture mix and incubated in a growth chamber(20℃).Results suggested that the control seedlings of three cultivars appeared quite healthy,while the seedlings inoculated with HW7-1 turned yellowing leaves,seedling stunting or even death after 22 days post-inoculation.V.longisporum was re-isolated from he yellow leaves,thus fulfilling Koch's postulates.Moreover,compared to the control treatments,inoculation with HW7-1 caused flowering delay and seed yield reduction on Tayou 2 with production of microsclerotia on the stems.To our knowledge,this is the first report of V.longisporum lineage A1/D3 on rapeseed in northwestern China.展开更多
Upland crop-rice cropping systems(UCR)facilitate sustainable agricultural intensification.Accurate UCR cultivation mapping is needed to ensure food security,sustainable water management,and rural revitalization.Howeve...Upland crop-rice cropping systems(UCR)facilitate sustainable agricultural intensification.Accurate UCR cultivation mapping is needed to ensure food security,sustainable water management,and rural revitalization.However,datasets describing cropping systems are limited in spatial coverage and crop types.Mapping UCR is more challenging than crop identification and most existing approaches rely heavily on accurate phenology calendars and representative training samples,which limits its applications over large regions.We describe a novel algorithm(RRSS)for automatic mapping of upland crop-rice cropping systems using Sentinel-1 Synthetic Aperture Radar(SAR)and Sentinel-2 Multispectral Instrument(MSI)data.One indicator,the VV backscatter range,was proposed to discriminate UCR and another two indicators were designed by coupling greenness and pigment indices to further discriminate tobacco or oilseed UCR.The RRSS algorithm was applied to South China characterized by complex smallholder rice cropping systems and diverse topographic conditions.This study developed 10-m UCR maps of a major rice bowl in South China,the Xiang-Gan-Min(XGM)region.The performance of the RRSS algorithm was validated based on 5197 ground-truth reference sites,with an overall accuracy of 91.92%.There were7348 km^(2) areas of UCR,roughly one-half of them located in plains.The UCR was represented mainly by oilseed-UCR and tobacco-UCR,which contributed respectively 69%and 15%of UCR area.UCR patterns accounted for only one-tenth of rice production,which can be tripled by intensification from single rice cropping.Application to complex and fragmented subtropical regions suggested the spatiotemporal robustness of the RRSS algorithm,which could be further applied to generate 10-m UCR datasets for application at national or global scales.展开更多
Adiposity,synonymous with obesity,is prevalent among both children and adults with type 1 diabetes in China.Recent literature underscored the pathophysiological and socioeconomic factors associated with adiposity,and ...Adiposity,synonymous with obesity,is prevalent among both children and adults with type 1 diabetes in China.Recent literature underscored the pathophysiological and socioeconomic factors associated with adiposity,and consistently highlighted its impact on cardiovascular,kidney,and metabolic diseases among Chinese individuals with type 1 diabetes.Addressing and managing adiposity in individuals with type 1 diabetes are complicated and entail comprehensive approaches including lifestyle modifications,cognitive-behavioral therapy,insulin dose titration,and other diabetes treatment medications.The condition calls for coordination among policymakers,researchers,clinicians,and patients.展开更多
China has successfully launched six lunar probes so far.From Chang'E-1 to Chang'E-4,they completed the circling,landing and roving exploration,of which Chang'E-4 was the first landing on the far side of th...China has successfully launched six lunar probes so far.From Chang'E-1 to Chang'E-4,they completed the circling,landing and roving exploration,of which Chang'E-4 was the first landing on the far side of the Moon in human history.Chang'E-5 was launched in December 2020,bringing back 1731 g of lunar soil samples.Through the detailed analysis of the samples,the scientists understand the history of late lunar volcanism,specifically extending lunar volcanism by about 800 million to 1 billion years,and proposed possible mechanisms.In addition,there are many new understandings of space weathering such as meteorite impacts and solar wind radiation on the Moon.China's first Mars exploration mission Tianwen-1 was successfully launched in July 2021.Through the study of scientific data,a number of important scientific achievements have been made in the topography,water environment and shallow surface structure of Mars.This paper introduces the main scientific achievements of Chang'E-4,Chang'E-5 and Tianwen-1 in the past two years,excluding technical and engineering contents.Due to the large number of articles involved,this paper only introduces part of the results.展开更多
Exploration and development of large gas fields is an important way for a country to rapidly develop its natural gas industry.From 1991 to 2020,China discovered 68 new large gas fields,boosting its annual gas output t...Exploration and development of large gas fields is an important way for a country to rapidly develop its natural gas industry.From 1991 to 2020,China discovered 68 new large gas fields,boosting its annual gas output to 1925×108m3in 2020,making it the fourth largest gas-producing country in the world.Based on 1696 molecular components and carbon isotopic composition data of alkane gas in 70 large gas fields in China,the characteristics of carbon isotopic composition of alkane gas in large gas fields in China were obtained.The lightest and average values ofδ^(13)C_(1),δ13C2,δ13C3andδ13C4become heavier with increasing carbon number,while the heaviest values ofδ^(13)C_(1),δ13C2,δ13C3andδ13C4become lighter with increasing carbon number.Theδ^(13)C_(1)values of large gas fields in China range from-71.2‰to-11.4‰(specifically,from-71.2‰to-56.4‰for bacterial gas,from-54.4‰to-21.6‰for oil-related gas,from-49.3‰to-18.9‰for coal-derived gas,and from-35.6‰to-11.4‰for abiogenic gas).Based on these data,theδ^(13)C_(1)chart of large gas fields in China was plotted.Moreover,theδ^(13)C_(1)values of natural gas in China range from-107.1‰to-8.9‰,specifically,from-1071%o to-55.1‰for bacterial gas,from-54.4‰to-21.6‰for oil-related gas,from-49.3‰to-13.3‰for coal-derived gas,and from-36.2‰to-8.9‰for abiogenic gas.Based on these data,theδ^(13)C_(1)chart of natural gas in China was plotted.展开更多
INTRODUCTIONWith the coming of the 21st century, we are faced the problems of the environment, re-sources and population. The ocean is regarded as supplier of resources such as food, minerals,energy and space, and pla...INTRODUCTIONWith the coming of the 21st century, we are faced the problems of the environment, re-sources and population. The ocean is regarded as supplier of resources such as food, minerals,energy and space, and plays an important role in sustainable economic development. At thesame time the ocean has a very important effect on the worldwide environmental changes.展开更多
Background:The current study was conducted to investigate the individual and combined occurrence of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON)and zearalenone(ZEN)in feeds from various Provinces of China during 2018 ...Background:The current study was conducted to investigate the individual and combined occurrence of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON)and zearalenone(ZEN)in feeds from various Provinces of China during 2018 to 2020.A total of 3,507 feed samples,including 2,090 feed ingredients and 1,417 complete feed samples,were collected from different areas of China for mycotoxins analysis.Results:The individual contamination of AFB_(1),DON and ZEN were present in more than 81.9%,96.4% and 96.9% of feed samples,respectively,with average concentration ranges of AFB_(1) between 1.2-27.4μg/kg,DON between 458.0-1,925.4μg/kg and ZEN between 48.1-326.8μg/kg.Notably,0.9%,0.5% and 0.1% of feed ingredients,and 1.2-12.8%,0.9-2.9% and 0-8.9% of complete feeds for pigs,poultry and ruminants with AFB_(1),ZEN and DON that exceeded China’s safety standards,respectively.Moreover,more than 81.5%of feed ingredients and 95.7% of complete feeds were co-contaminated with various combinations of these mycotoxins.Conclusion:This study indicates that the feeds in China were universally contaminated with AFB_(1),DON and ZEN during the past 3 years.These findings highlight the significance of monitoring mycotoxin contaminant levels in the domestic animal feed,and the importance of carrying out feed administration and remediation strategies for mycotoxin control.展开更多
This paper reports, for the first time, observation results of the Coherent Beacon System(CBS) onboard the China SeismoElectromagnetic Satellite-1(CSES-1). We describe the CBS, and the Computerized Ionospheric Tomogra...This paper reports, for the first time, observation results of the Coherent Beacon System(CBS) onboard the China SeismoElectromagnetic Satellite-1(CSES-1). We describe the CBS, and the Computerized Ionospheric Tomography(CIT) algorithm program is validated by numerical experiment. Two examples are shown, for daytime and nighttime respectively. The Equatorial Ionization Anomaly(EIA) can be seen, and the northern crest core is located at ~20°N in the reconstruction image at 07:28 UTC on 20 July 2018(daytime).Disturbances are shown in the reconstruction image at 18:40 UTC on 13 July 2018(nighttime). We find that beacon measurements are more consistent with ionosonde measurements than model results, by comparing Nm F2 at three sites at Lanzhou, Chongqing, and Kunming; consistency with ionosonde measurements validates beacon measurements. Finally, we have studied Vertical Total Electron Content(VTEC) variations from ground to ~500 km(the height of CSES-1 orbit) and ratios of VTEC between beacon measurements and CODE(Center for Orbit Determination in Europe) data. VTEC variation from ground to ~500 km has a range of 7.2–16.5 TECU for the daytime case and a range of 1.1–1.7 TECU for the nighttime case. The Beacon/CODE ratio of VTEC varies with latitude and time. The mean Beacon/CODE ratio is 0.69 for the daytime case and 0.26 for the nighttime case. The fact that the nighttime case yields lower ratios indicates the higher altitude of the ionosphere during nighttime when the ionosphere is assumed to be a thin layer.展开更多
By assuming constant winter wheat varieties and agricultural practices in China, the influence of climate change on winter wheat is simulated using the corrected future climate projections under SRES A2 and A1B scenar...By assuming constant winter wheat varieties and agricultural practices in China, the influence of climate change on winter wheat is simulated using the corrected future climate projections under SRES A2 and A1B scenarios from 2012 to 2100, respectively. The results indicate that the growth of winter wheat would be strongly influenced by climate change in future. The average flowering and maturity dates of winter wheat would advance by 26 and 27 days under scenario A2, and by 23 and 24 days respectively under scenario A1B from 2012 to 2100. The simulated potential productivity of winter wheat shows a decrease of 14.3% and 12.5% for scenarios A2 and A1B respectively without the fertilization effect of CO2, while an increase of 1.3% and 0.6% with the fertilization effect of CO2. Additionally, for northern China, the simulated potential productivity would markedly decrease under both scenarios, independent with the fertilization effect of CO2, which indicates that the current planted winter wheat would be more vulnerable than that in southern China. The most likely reason is the current winter wheat varieties in northern China are winter varieties or strong winter varieties, which need some days of low temperature for dormancy. While in southern China, the winter wheat is spring or half winter varieties and can grow slowly during winter, thus, they would be affected slightly when winter temperature increases. The results of this study may have important implications for adaptation measures.展开更多
Objective The Yanshan Fold Belt is located within the northern margin of the North China platform and contains welldeveloped and widespread Neoproterozoic and Mesoproterozoic sedimentary units with a total thickness o...Objective The Yanshan Fold Belt is located within the northern margin of the North China platform and contains welldeveloped and widespread Neoproterozoic and Mesoproterozoic sedimentary units with a total thickness of up to 9000 m.Previous studies identified many oil seedlings as well as asphalt and ancient hydrocarbon reservoirs in Northern Hebei depression and western Liaoning depression.This research indicates that the Mesoproterozoic and Neoproterozoic sedimentary units are ideally suited for the formation of significant oil and gas resources.The Niu D1 well was drilled by the China Geological Survey(CGS)in the Niuyingzi area and intercepted oil immersions and oil-and gas-bearing units within a limestone reservoir in the middle Proterozoic Gaoyuzhuang Formation(Fig.1).This study presents new biomarker compound and carbon isotope data that indicate that the oil within this formation was derived from hydrocarbon source rocks of the Hongshuizhuang Formation,part of the Mesoproterozoic Jixian Series,and the reservoir type is overthrust fault fractured anticline hydrocarbon reservoir.The oil reservoir within the Gaoyuzhuang Formation limestone might represent the oldest oil reservoir discovered to date within the Yanliao faulted depression zone.展开更多
Little information is available on the prevalence of drug-resistance mutations in patients harboring the human immunodeficiency virus type 1(HIV-1) circulating recombinant form(CRF)07_BC variant in Sichuan, China. Thi...Little information is available on the prevalence of drug-resistance mutations in patients harboring the human immunodeficiency virus type 1(HIV-1) circulating recombinant form(CRF)07_BC variant in Sichuan, China. This study examined 375 plasma samples from patients with HIV-1 who were infected with the CRF07_BC strain, including 104 drug-naive participants and 271 in whom antiretroviral therapy(ART) had failed. Only one participant in the drug-naive group had a drug-resistance mutation(M46L), compared with 31.73% of those in whom ART had failed. Further analysis showed that 19.56% of strains contained mutations conferring resistance to non-nucleoside reverse transcriptase inhibitors(NNRTIs) alone, 0.74% were resistant to nucleoside reverse transcriptase inhibitors(NRTIs) alone, and 11.44% were dual-resistant to both NRTIs and NNRTIs. The most common mutation in the ART-failure group was M184V(35.88%), K103N(45.01%), Y181C(17.33%), and G190S/A(15.88%). The percentages of HIV-1 strains resistant to lamivudine, emtricitabine, efavirenz, etravirine, and nevirapine were 10.70%, 10.70%, 28.04%, 7.75%, and 26.20%, respectively. To explore site variants possibly related to drug resistance, variations in the ancestor/consensus CRF07_BC sequences from the therapy-naive and ART-failure groups were compared, and seven mutations at six positions were identified as being significantly differently distributed between the two groups(p<0.05). Detailed sequence data will provide information on CRF07_BC genetic characterizations, and improve our understanding of antiretroviral susceptibility and the evolution of drug-resistance mutations. This will be valuable in developing and implementing local public-health approaches for HIV drug-resistance prevention and treatment.展开更多
BACKGROUND Oral-facial-digital syndrome type 1(OFD1) is a rare ciliopathy mainly with an Xlinked dominant pattern of inheritance, which is caused by mutations in the OFD1 gene. The OFD1 protein is located within the c...BACKGROUND Oral-facial-digital syndrome type 1(OFD1) is a rare ciliopathy mainly with an Xlinked dominant pattern of inheritance, which is caused by mutations in the OFD1 gene. The OFD1 protein is located within the centrosomes and basal bodies of the primary cilia. It is reported that approximately 15%–50% cases of OFD1 progress to end-stage renal disease(ESRD) following development of polycystic kidney diseases(PKD). Here we report a pair of childhood male twins who presented only renal failure and PKD caused by an OFD1 mutation in China.CASE SUMMARY A pair of 14-year male twins were hospitalized with a complaint of abnormal renal function for nine days. They both complained of ankle pain for 3 mo vs 2 wk, respectively. They denied fever, abdominal pain, daytime or nighttime enuresis, urgency, dysuria, or gross hematuria. Laboratory tests at a local hospital showed renal failure(serum creatinine 485 μmol/L vs 442 μmol/L, blood urea nitrogen 14.7 mol/L vs 14.5 mol/L) and anemia(hemoglobin 88 g/L vs 98 g/L).The twins are monozygotic. There was no abnormal birth, past medical, or family history. Clinical data were analyzed and genetic analysis on PKD was carried out in the twins by next-generation sequencing. The results showed that the twins presented low-molecular-weight proteinuria, hyposthenuria, anemia, renal failure, and renal polycystic changes. Genetic tests showed that the twins both carried a hemizygous mutation in exon 19 c.2524 G>A(p. G842 R) of the OFD1 gene. Their mother heterozygously carried the same mutation as the twins but was without any phenotypes while their father was normal.CONCLUSION We have reported a pair of childhood male twins with an OFD1 mutation who presented ESRD and PKD but without any other phenotypes of OFD1 in China.展开更多
The class 1 integron and complex gene cassettes among different species of clinical isolates in northern China were characterized in this study. 383 clinical isolates were obtained from northern China, and class 1 int...The class 1 integron and complex gene cassettes among different species of clinical isolates in northern China were characterized in this study. 383 clinical isolates were obtained from northern China, and class 1 integrons containing gene cassettes widely distributed among gram negative clinical isolates was observed. We find that the class 1 integron showed positive correlation with multidrug resistance phenotype of gram negative bacteria. In addition, we find that isolates belonged to one species harbored different types of gene cassette arrays, while same types of gene cassette arrays were observed in different species of isolates. The diversity of gene cassette arrays among the isolates indicated the complexity of multidrug resistance in clinical isolates in northern China.展开更多
The 1st International Conference on Data-driven Knowledge Discovery: When Data Science Meets Information Science took place at the National Science Library (NSL), Chinese Academy of Sciences (CAS) in Beijing from...The 1st International Conference on Data-driven Knowledge Discovery: When Data Science Meets Information Science took place at the National Science Library (NSL), Chinese Academy of Sciences (CAS) in Beijing from June 19 till June 22, 2016. The Conference was opened by NSL Director Xiangyang Huang, who placed the event within the goals of the Library, and lauded the spirit of intemational collaboration in the area of data science and knowledge discovery. The whole event was an encouraging success with over 370 registered participants and highly enlightening presentations. The Conference was organized by the Journal of Data andlnformation Science (JDIS) to bring the Joumal to the attention of an international and local audience.展开更多
文摘This article will firstly discuss the context overview of English teaching and learning in China. Under thiscircumstance, a problematic element will be examined of the New Senior English for China Student’s Book 1 and critical appraisal ofhow this element relates to other elements of curriculum development will be analyzed. The recommended changes and demonstrationmechanisms for evaluating the changes are put forward in the last two parts.
基金supported by the Earmarked Fund for CARS-12 from National Modern Agricultural Technology System.
文摘Five stems of rapeseed with abundant black microsclerotia were collected from Huangyuan County of Qinghai Province,China,and fungal isolates were obtained from the stems.They were identified based on morphology,molecular features and specific PCR detection.The results showed that the 10 fungal isolates belonged to Verticillium longisporum lineage A1/D3.One of the 10 isolates(HW7-1)was tested for virulence on three species of rapeseed,including B.napus Zhongshuang 9,B.rapa Qingyou 9 and B.juncea Tayou 2 by conidia inoculation of HW7-1 on roots of young seedlings.Control seedlings were inoculated with V.dahliae conidia or water alone.The seedlings of these treatments were transplanted in culture mix and incubated in a growth chamber(20℃).Results suggested that the control seedlings of three cultivars appeared quite healthy,while the seedlings inoculated with HW7-1 turned yellowing leaves,seedling stunting or even death after 22 days post-inoculation.V.longisporum was re-isolated from he yellow leaves,thus fulfilling Koch's postulates.Moreover,compared to the control treatments,inoculation with HW7-1 caused flowering delay and seed yield reduction on Tayou 2 with production of microsclerotia on the stems.To our knowledge,this is the first report of V.longisporum lineage A1/D3 on rapeseed in northwestern China.
基金supported by the National Natural Science Foundation of China(42171325,41771468)the National Key Research and Development Program of China(2022YFD2001101)+1 种基金the Science Bureau of Fujian Province(2023Y0042)the Finance Department and the Digital Economy Alliance of Fujian Province。
文摘Upland crop-rice cropping systems(UCR)facilitate sustainable agricultural intensification.Accurate UCR cultivation mapping is needed to ensure food security,sustainable water management,and rural revitalization.However,datasets describing cropping systems are limited in spatial coverage and crop types.Mapping UCR is more challenging than crop identification and most existing approaches rely heavily on accurate phenology calendars and representative training samples,which limits its applications over large regions.We describe a novel algorithm(RRSS)for automatic mapping of upland crop-rice cropping systems using Sentinel-1 Synthetic Aperture Radar(SAR)and Sentinel-2 Multispectral Instrument(MSI)data.One indicator,the VV backscatter range,was proposed to discriminate UCR and another two indicators were designed by coupling greenness and pigment indices to further discriminate tobacco or oilseed UCR.The RRSS algorithm was applied to South China characterized by complex smallholder rice cropping systems and diverse topographic conditions.This study developed 10-m UCR maps of a major rice bowl in South China,the Xiang-Gan-Min(XGM)region.The performance of the RRSS algorithm was validated based on 5197 ground-truth reference sites,with an overall accuracy of 91.92%.There were7348 km^(2) areas of UCR,roughly one-half of them located in plains.The UCR was represented mainly by oilseed-UCR and tobacco-UCR,which contributed respectively 69%and 15%of UCR area.UCR patterns accounted for only one-tenth of rice production,which can be tripled by intensification from single rice cropping.Application to complex and fragmented subtropical regions suggested the spatiotemporal robustness of the RRSS algorithm,which could be further applied to generate 10-m UCR datasets for application at national or global scales.
基金Supported by 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,No.ZYYC24001.
文摘Adiposity,synonymous with obesity,is prevalent among both children and adults with type 1 diabetes in China.Recent literature underscored the pathophysiological and socioeconomic factors associated with adiposity,and consistently highlighted its impact on cardiovascular,kidney,and metabolic diseases among Chinese individuals with type 1 diabetes.Addressing and managing adiposity in individuals with type 1 diabetes are complicated and entail comprehensive approaches including lifestyle modifications,cognitive-behavioral therapy,insulin dose titration,and other diabetes treatment medications.The condition calls for coordination among policymakers,researchers,clinicians,and patients.
文摘China has successfully launched six lunar probes so far.From Chang'E-1 to Chang'E-4,they completed the circling,landing and roving exploration,of which Chang'E-4 was the first landing on the far side of the Moon in human history.Chang'E-5 was launched in December 2020,bringing back 1731 g of lunar soil samples.Through the detailed analysis of the samples,the scientists understand the history of late lunar volcanism,specifically extending lunar volcanism by about 800 million to 1 billion years,and proposed possible mechanisms.In addition,there are many new understandings of space weathering such as meteorite impacts and solar wind radiation on the Moon.China's first Mars exploration mission Tianwen-1 was successfully launched in July 2021.Through the study of scientific data,a number of important scientific achievements have been made in the topography,water environment and shallow surface structure of Mars.This paper introduces the main scientific achievements of Chang'E-4,Chang'E-5 and Tianwen-1 in the past two years,excluding technical and engineering contents.Due to the large number of articles involved,this paper only introduces part of the results.
基金Supported by the National Natural Science Foundation of China(41472120)General Project of National Natural Science Foundation of China(42272188)+1 种基金Special Fund of PetroChina and New Energy Branch(2023YQX10101)Petrochemical Joint Fund of Fund Committee(U20B6001)。
文摘Exploration and development of large gas fields is an important way for a country to rapidly develop its natural gas industry.From 1991 to 2020,China discovered 68 new large gas fields,boosting its annual gas output to 1925×108m3in 2020,making it the fourth largest gas-producing country in the world.Based on 1696 molecular components and carbon isotopic composition data of alkane gas in 70 large gas fields in China,the characteristics of carbon isotopic composition of alkane gas in large gas fields in China were obtained.The lightest and average values ofδ^(13)C_(1),δ13C2,δ13C3andδ13C4become heavier with increasing carbon number,while the heaviest values ofδ^(13)C_(1),δ13C2,δ13C3andδ13C4become lighter with increasing carbon number.Theδ^(13)C_(1)values of large gas fields in China range from-71.2‰to-11.4‰(specifically,from-71.2‰to-56.4‰for bacterial gas,from-54.4‰to-21.6‰for oil-related gas,from-49.3‰to-18.9‰for coal-derived gas,and from-35.6‰to-11.4‰for abiogenic gas).Based on these data,theδ^(13)C_(1)chart of large gas fields in China was plotted.Moreover,theδ^(13)C_(1)values of natural gas in China range from-107.1‰to-8.9‰,specifically,from-1071%o to-55.1‰for bacterial gas,from-54.4‰to-21.6‰for oil-related gas,from-49.3‰to-13.3‰for coal-derived gas,and from-36.2‰to-8.9‰for abiogenic gas.Based on these data,theδ^(13)C_(1)chart of natural gas in China was plotted.
文摘INTRODUCTIONWith the coming of the 21st century, we are faced the problems of the environment, re-sources and population. The ocean is regarded as supplier of resources such as food, minerals,energy and space, and plays an important role in sustainable economic development. At thesame time the ocean has a very important effect on the worldwide environmental changes.
基金supported by the Chinese Natural Science Foundation projects(32072775 and 31772636)National Key Research and Development Program of China(2016YFD0501207)JiangSu Aomai Bio-Technology Co.,Ltd.(Nanjing,China).
文摘Background:The current study was conducted to investigate the individual and combined occurrence of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON)and zearalenone(ZEN)in feeds from various Provinces of China during 2018 to 2020.A total of 3,507 feed samples,including 2,090 feed ingredients and 1,417 complete feed samples,were collected from different areas of China for mycotoxins analysis.Results:The individual contamination of AFB_(1),DON and ZEN were present in more than 81.9%,96.4% and 96.9% of feed samples,respectively,with average concentration ranges of AFB_(1) between 1.2-27.4μg/kg,DON between 458.0-1,925.4μg/kg and ZEN between 48.1-326.8μg/kg.Notably,0.9%,0.5% and 0.1% of feed ingredients,and 1.2-12.8%,0.9-2.9% and 0-8.9% of complete feeds for pigs,poultry and ruminants with AFB_(1),ZEN and DON that exceeded China’s safety standards,respectively.Moreover,more than 81.5%of feed ingredients and 95.7% of complete feeds were co-contaminated with various combinations of these mycotoxins.Conclusion:This study indicates that the feeds in China were universally contaminated with AFB_(1),DON and ZEN during the past 3 years.These findings highlight the significance of monitoring mycotoxin contaminant levels in the domestic animal feed,and the importance of carrying out feed administration and remediation strategies for mycotoxin control.
基金supported by the “China Seismo-Electromagnetic Satellite (CSES)” projectthe 13th Five-Year Technology Program (Grant No. 315030409)
文摘This paper reports, for the first time, observation results of the Coherent Beacon System(CBS) onboard the China SeismoElectromagnetic Satellite-1(CSES-1). We describe the CBS, and the Computerized Ionospheric Tomography(CIT) algorithm program is validated by numerical experiment. Two examples are shown, for daytime and nighttime respectively. The Equatorial Ionization Anomaly(EIA) can be seen, and the northern crest core is located at ~20°N in the reconstruction image at 07:28 UTC on 20 July 2018(daytime).Disturbances are shown in the reconstruction image at 18:40 UTC on 13 July 2018(nighttime). We find that beacon measurements are more consistent with ionosonde measurements than model results, by comparing Nm F2 at three sites at Lanzhou, Chongqing, and Kunming; consistency with ionosonde measurements validates beacon measurements. Finally, we have studied Vertical Total Electron Content(VTEC) variations from ground to ~500 km(the height of CSES-1 orbit) and ratios of VTEC between beacon measurements and CODE(Center for Orbit Determination in Europe) data. VTEC variation from ground to ~500 km has a range of 7.2–16.5 TECU for the daytime case and a range of 1.1–1.7 TECU for the nighttime case. The Beacon/CODE ratio of VTEC varies with latitude and time. The mean Beacon/CODE ratio is 0.69 for the daytime case and 0.26 for the nighttime case. The fact that the nighttime case yields lower ratios indicates the higher altitude of the ionosphere during nighttime when the ionosphere is assumed to be a thin layer.
基金supported by the impact of agrometeorology disasters on agriculture under climate change in China(No.GYHY201106021)National Basic Research Program of China(No.2012CB955301)
文摘By assuming constant winter wheat varieties and agricultural practices in China, the influence of climate change on winter wheat is simulated using the corrected future climate projections under SRES A2 and A1B scenarios from 2012 to 2100, respectively. The results indicate that the growth of winter wheat would be strongly influenced by climate change in future. The average flowering and maturity dates of winter wheat would advance by 26 and 27 days under scenario A2, and by 23 and 24 days respectively under scenario A1B from 2012 to 2100. The simulated potential productivity of winter wheat shows a decrease of 14.3% and 12.5% for scenarios A2 and A1B respectively without the fertilization effect of CO2, while an increase of 1.3% and 0.6% with the fertilization effect of CO2. Additionally, for northern China, the simulated potential productivity would markedly decrease under both scenarios, independent with the fertilization effect of CO2, which indicates that the current planted winter wheat would be more vulnerable than that in southern China. The most likely reason is the current winter wheat varieties in northern China are winter varieties or strong winter varieties, which need some days of low temperature for dormancy. While in southern China, the winter wheat is spring or half winter varieties and can grow slowly during winter, thus, they would be affected slightly when winter temperature increases. The results of this study may have important implications for adaptation measures.
基金funded by the China Geological Survey Project(Grant No.DD20190098).
文摘Objective The Yanshan Fold Belt is located within the northern margin of the North China platform and contains welldeveloped and widespread Neoproterozoic and Mesoproterozoic sedimentary units with a total thickness of up to 9000 m.Previous studies identified many oil seedlings as well as asphalt and ancient hydrocarbon reservoirs in Northern Hebei depression and western Liaoning depression.This research indicates that the Mesoproterozoic and Neoproterozoic sedimentary units are ideally suited for the formation of significant oil and gas resources.The Niu D1 well was drilled by the China Geological Survey(CGS)in the Niuyingzi area and intercepted oil immersions and oil-and gas-bearing units within a limestone reservoir in the middle Proterozoic Gaoyuzhuang Formation(Fig.1).This study presents new biomarker compound and carbon isotope data that indicate that the oil within this formation was derived from hydrocarbon source rocks of the Hongshuizhuang Formation,part of the Mesoproterozoic Jixian Series,and the reservoir type is overthrust fault fractured anticline hydrocarbon reservoir.The oil reservoir within the Gaoyuzhuang Formation limestone might represent the oldest oil reservoir discovered to date within the Yanliao faulted depression zone.
基金supported by the Chinese Government AIDS Program (grant number 2008ZX001-016)the China 4th Global Fund AIDS Program (grant number CHN-405-G05-H)a Sichuan Provincial Health Department research project (number 120154)
文摘Little information is available on the prevalence of drug-resistance mutations in patients harboring the human immunodeficiency virus type 1(HIV-1) circulating recombinant form(CRF)07_BC variant in Sichuan, China. This study examined 375 plasma samples from patients with HIV-1 who were infected with the CRF07_BC strain, including 104 drug-naive participants and 271 in whom antiretroviral therapy(ART) had failed. Only one participant in the drug-naive group had a drug-resistance mutation(M46L), compared with 31.73% of those in whom ART had failed. Further analysis showed that 19.56% of strains contained mutations conferring resistance to non-nucleoside reverse transcriptase inhibitors(NNRTIs) alone, 0.74% were resistant to nucleoside reverse transcriptase inhibitors(NRTIs) alone, and 11.44% were dual-resistant to both NRTIs and NNRTIs. The most common mutation in the ART-failure group was M184V(35.88%), K103N(45.01%), Y181C(17.33%), and G190S/A(15.88%). The percentages of HIV-1 strains resistant to lamivudine, emtricitabine, efavirenz, etravirine, and nevirapine were 10.70%, 10.70%, 28.04%, 7.75%, and 26.20%, respectively. To explore site variants possibly related to drug resistance, variations in the ancestor/consensus CRF07_BC sequences from the therapy-naive and ART-failure groups were compared, and seven mutations at six positions were identified as being significantly differently distributed between the two groups(p<0.05). Detailed sequence data will provide information on CRF07_BC genetic characterizations, and improve our understanding of antiretroviral susceptibility and the evolution of drug-resistance mutations. This will be valuable in developing and implementing local public-health approaches for HIV drug-resistance prevention and treatment.
文摘BACKGROUND Oral-facial-digital syndrome type 1(OFD1) is a rare ciliopathy mainly with an Xlinked dominant pattern of inheritance, which is caused by mutations in the OFD1 gene. The OFD1 protein is located within the centrosomes and basal bodies of the primary cilia. It is reported that approximately 15%–50% cases of OFD1 progress to end-stage renal disease(ESRD) following development of polycystic kidney diseases(PKD). Here we report a pair of childhood male twins who presented only renal failure and PKD caused by an OFD1 mutation in China.CASE SUMMARY A pair of 14-year male twins were hospitalized with a complaint of abnormal renal function for nine days. They both complained of ankle pain for 3 mo vs 2 wk, respectively. They denied fever, abdominal pain, daytime or nighttime enuresis, urgency, dysuria, or gross hematuria. Laboratory tests at a local hospital showed renal failure(serum creatinine 485 μmol/L vs 442 μmol/L, blood urea nitrogen 14.7 mol/L vs 14.5 mol/L) and anemia(hemoglobin 88 g/L vs 98 g/L).The twins are monozygotic. There was no abnormal birth, past medical, or family history. Clinical data were analyzed and genetic analysis on PKD was carried out in the twins by next-generation sequencing. The results showed that the twins presented low-molecular-weight proteinuria, hyposthenuria, anemia, renal failure, and renal polycystic changes. Genetic tests showed that the twins both carried a hemizygous mutation in exon 19 c.2524 G>A(p. G842 R) of the OFD1 gene. Their mother heterozygously carried the same mutation as the twins but was without any phenotypes while their father was normal.CONCLUSION We have reported a pair of childhood male twins with an OFD1 mutation who presented ESRD and PKD but without any other phenotypes of OFD1 in China.
基金supported by Twelfth Five-Year Mega Project of Research on The Prevention and Control of HIV/AIDS,Viral Hepatitis Infectious Diseases 2013ZX10004-217 from the Ministry of Science and Technology,People’s Republic of China,the Project Sponsored by the Young Scholar Scientific Research Foundation of China CDC(No.2013A101)General Program of State Key Laboratory for Infections Disease Prevention and Control(No.2012SKLID205)
文摘The class 1 integron and complex gene cassettes among different species of clinical isolates in northern China were characterized in this study. 383 clinical isolates were obtained from northern China, and class 1 integrons containing gene cassettes widely distributed among gram negative clinical isolates was observed. We find that the class 1 integron showed positive correlation with multidrug resistance phenotype of gram negative bacteria. In addition, we find that isolates belonged to one species harbored different types of gene cassette arrays, while same types of gene cassette arrays were observed in different species of isolates. The diversity of gene cassette arrays among the isolates indicated the complexity of multidrug resistance in clinical isolates in northern China.
文摘The 1st International Conference on Data-driven Knowledge Discovery: When Data Science Meets Information Science took place at the National Science Library (NSL), Chinese Academy of Sciences (CAS) in Beijing from June 19 till June 22, 2016. The Conference was opened by NSL Director Xiangyang Huang, who placed the event within the goals of the Library, and lauded the spirit of intemational collaboration in the area of data science and knowledge discovery. The whole event was an encouraging success with over 370 registered participants and highly enlightening presentations. The Conference was organized by the Journal of Data andlnformation Science (JDIS) to bring the Joumal to the attention of an international and local audience.