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Analysis of New Senior English for China Student’s Book 1
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作者 Xia Qian 《语言与文化研究》 2024年第4期128-132,共5页
This article will firstly discuss the context overview of English teaching and learning in China. Under thiscircumstance, a problematic element will be examined of the New Senior English for China Student’s Book 1 an... This article will firstly discuss the context overview of English teaching and learning in China. Under thiscircumstance, a problematic element will be examined of the New Senior English for China Student’s Book 1 and critical appraisal ofhow this element relates to other elements of curriculum development will be analyzed. The recommended changes and demonstrationmechanisms for evaluating the changes are put forward in the last two parts. 展开更多
关键词 New Senior English for china Student’s Book 1 Assessment Critical appraisal Curriculum development CHANGES
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华南型黄瓜新品种中农脆绿1号的选育
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作者 张丛莹 顾兴芳 +4 位作者 苗晗 董邵云 刘小萍 官健涛 张圣平 《中国蔬菜》 北大核心 2024年第7期113-115,共3页
中农脆绿1号是以雌性系171054为母本,以自交系17905为父本配制而成的华南型黄瓜一代杂种。该品种为雌性系,植株生长势强,分枝性较强,耐低温弱光性好。商品瓜圆筒形,瓜把短,刺瘤中等大小,无棱,白刺稀疏,瓜色花绿,平均瓜长17.0 cm,横径3.7... 中农脆绿1号是以雌性系171054为母本,以自交系17905为父本配制而成的华南型黄瓜一代杂种。该品种为雌性系,植株生长势强,分枝性较强,耐低温弱光性好。商品瓜圆筒形,瓜把短,刺瘤中等大小,无棱,白刺稀疏,瓜色花绿,平均瓜长17.0 cm,横径3.7 cm,心腔小,果肉淡绿色。高抗CMV,抗WMV、褐斑病,中抗白粉病、枯萎病,早熟,每667 m^(2)产量7 000~10 000 kg,适宜日光温室和春、秋大棚栽培。 展开更多
关键词 黄瓜 华南型 中农脆绿1 一代杂种 抗病
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Identification and virulence test of a new pathogen that causes verticillium striping on rapeseed in northwestern China 被引量:1
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作者 We Si Ruisheng Wang +3 位作者 Mingde Wu Long Yang Guoqing Li Jing Zhang 《Oil Crop Science》 CSCD 2024年第1期8-19,共12页
Five stems of rapeseed with abundant black microsclerotia were collected from Huangyuan County of Qinghai Province,China,and fungal isolates were obtained from the stems.They were identified based on morphology,molecu... Five stems of rapeseed with abundant black microsclerotia were collected from Huangyuan County of Qinghai Province,China,and fungal isolates were obtained from the stems.They were identified based on morphology,molecular features and specific PCR detection.The results showed that the 10 fungal isolates belonged to Verticillium longisporum lineage A1/D3.One of the 10 isolates(HW7-1)was tested for virulence on three species of rapeseed,including B.napus Zhongshuang 9,B.rapa Qingyou 9 and B.juncea Tayou 2 by conidia inoculation of HW7-1 on roots of young seedlings.Control seedlings were inoculated with V.dahliae conidia or water alone.The seedlings of these treatments were transplanted in culture mix and incubated in a growth chamber(20℃).Results suggested that the control seedlings of three cultivars appeared quite healthy,while the seedlings inoculated with HW7-1 turned yellowing leaves,seedling stunting or even death after 22 days post-inoculation.V.longisporum was re-isolated from he yellow leaves,thus fulfilling Koch's postulates.Moreover,compared to the control treatments,inoculation with HW7-1 caused flowering delay and seed yield reduction on Tayou 2 with production of microsclerotia on the stems.To our knowledge,this is the first report of V.longisporum lineage A1/D3 on rapeseed in northwestern China. 展开更多
关键词 Verticillium longisporum lineage A1/D3 VIRULENCE RAPESEED china
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中华人民共和国地质图(1∶150万)空间数据库建设方法
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作者 袁启玉 李仰春 +8 位作者 吴亮 黄辉 李超 李智佩 谷永昌 付俊彧 杨祝良 尹福光 赵小明 《地质学刊》 CAS 2024年第1期68-75,共8页
依托MapGIS平台,应用新技术和新方法,根据统一标准和要求编制了中华人民共和国地质图(1∶150万)和图形空间数据库。该图集成了近20多年来全国1∶5万和1∶25万区域地质调查、重点成矿区带1∶50万~1∶100万地质编图、部分省区地质志、基... 依托MapGIS平台,应用新技术和新方法,根据统一标准和要求编制了中华人民共和国地质图(1∶150万)和图形空间数据库。该图集成了近20多年来全国1∶5万和1∶25万区域地质调查、重点成矿区带1∶50万~1∶100万地质编图、部分省区地质志、基础地质科学研究等新成果和新资料,系统更新了全国区域地层系统、全国岩浆岩时空序列及变质岩分布与变质作用框架,建立并完善了区域地层格架,划分了全国大地构造单元,新确认一批区域性重要构造界面等。应用计算机辅助智能地质编图技术,华北、东北、华东、中南、西南、西北六大区同时编图,按省(区)分别进行地质单元、地理数据、数据结构无缝拼接,绘制“全国地质一张图”,形成库图一体成果。数据库数据量约1.65 GB,标示地质体78194个、火山口或火山喷发中心308个、重要化石点和化石群221个、金钉子12个、同位素年龄数据1197个、代表性钻孔(含大陆深钻)125个。该数据库填补了国家地质数据库体系空白,为地质大数据、“地质云”建设和服务提供了基础数据源,为自然资源规划管理、基础地质和资源环境背景研究、环境治理和灾害防治、国际合作等提供了重要的基础地质资料。 展开更多
关键词 中华人民共和国地质图 1150万 空间数据库 库图一体 MAPGIS
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Mapping upland crop–rice cropping systems for targeted sustainable intensification in South China
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作者 Bingwen Qiu Linhai Yu +4 位作者 Peng Yang Wenbin Wu Jianfeng Chen Xiaolin Zhu Mingjie Duan 《The Crop Journal》 SCIE CSCD 2024年第2期614-629,共16页
Upland crop-rice cropping systems(UCR)facilitate sustainable agricultural intensification.Accurate UCR cultivation mapping is needed to ensure food security,sustainable water management,and rural revitalization.Howeve... Upland crop-rice cropping systems(UCR)facilitate sustainable agricultural intensification.Accurate UCR cultivation mapping is needed to ensure food security,sustainable water management,and rural revitalization.However,datasets describing cropping systems are limited in spatial coverage and crop types.Mapping UCR is more challenging than crop identification and most existing approaches rely heavily on accurate phenology calendars and representative training samples,which limits its applications over large regions.We describe a novel algorithm(RRSS)for automatic mapping of upland crop-rice cropping systems using Sentinel-1 Synthetic Aperture Radar(SAR)and Sentinel-2 Multispectral Instrument(MSI)data.One indicator,the VV backscatter range,was proposed to discriminate UCR and another two indicators were designed by coupling greenness and pigment indices to further discriminate tobacco or oilseed UCR.The RRSS algorithm was applied to South China characterized by complex smallholder rice cropping systems and diverse topographic conditions.This study developed 10-m UCR maps of a major rice bowl in South China,the Xiang-Gan-Min(XGM)region.The performance of the RRSS algorithm was validated based on 5197 ground-truth reference sites,with an overall accuracy of 91.92%.There were7348 km^(2) areas of UCR,roughly one-half of them located in plains.The UCR was represented mainly by oilseed-UCR and tobacco-UCR,which contributed respectively 69%and 15%of UCR area.UCR patterns accounted for only one-tenth of rice production,which can be tripled by intensification from single rice cropping.Application to complex and fragmented subtropical regions suggested the spatiotemporal robustness of the RRSS algorithm,which could be further applied to generate 10-m UCR datasets for application at national or global scales. 展开更多
关键词 Cropping-pattern mapping Paddy rice Sentinel-1/2 china Sustainable intensification
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Adiposity in Chinese people with type 1 diabetes
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作者 Nian-Wei Wu Xia-Fei Lyu +1 位作者 Zhen-Mei An She-Yu Li 《World Journal of Diabetes》 SCIE 2024年第7期1404-1408,共5页
Adiposity,synonymous with obesity,is prevalent among both children and adults with type 1 diabetes in China.Recent literature underscored the pathophysiological and socioeconomic factors associated with adiposity,and ... Adiposity,synonymous with obesity,is prevalent among both children and adults with type 1 diabetes in China.Recent literature underscored the pathophysiological and socioeconomic factors associated with adiposity,and consistently highlighted its impact on cardiovascular,kidney,and metabolic diseases among Chinese individuals with type 1 diabetes.Addressing and managing adiposity in individuals with type 1 diabetes are complicated and entail comprehensive approaches including lifestyle modifications,cognitive-behavioral therapy,insulin dose titration,and other diabetes treatment medications.The condition calls for coordination among policymakers,researchers,clinicians,and patients. 展开更多
关键词 Type 1 diabetes china Metabolic syndrome OBESITY Anti-obesity medications
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Latest Scientific Results of China's Lunar and Deep Space Exploration(2022–2024)
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作者 XU Lin LI Lei +8 位作者 LIU Jianzhong LIN Honglei LI Yang LIU Yang XIE Lianghai ZHANG Jinhai QIAO Fuhao HAN Juanjuan ZOU Yongliao 《空间科学学报》 CAS CSCD 北大核心 2024年第4期622-632,共11页
China has successfully launched six lunar probes so far.From Chang'E-1 to Chang'E-4,they completed the circling,landing and roving exploration,of which Chang'E-4 was the first landing on the far side of th... China has successfully launched six lunar probes so far.From Chang'E-1 to Chang'E-4,they completed the circling,landing and roving exploration,of which Chang'E-4 was the first landing on the far side of the Moon in human history.Chang'E-5 was launched in December 2020,bringing back 1731 g of lunar soil samples.Through the detailed analysis of the samples,the scientists understand the history of late lunar volcanism,specifically extending lunar volcanism by about 800 million to 1 billion years,and proposed possible mechanisms.In addition,there are many new understandings of space weathering such as meteorite impacts and solar wind radiation on the Moon.China's first Mars exploration mission Tianwen-1 was successfully launched in July 2021.Through the study of scientific data,a number of important scientific achievements have been made in the topography,water environment and shallow surface structure of Mars.This paper introduces the main scientific achievements of Chang'E-4,Chang'E-5 and Tianwen-1 in the past two years,excluding technical and engineering contents.Due to the large number of articles involved,this paper only introduces part of the results. 展开更多
关键词 Lunar and deep space exploration of china Chang’E-4 mission Chang’E-5 mission Tianwen-1 mission
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Characteristics of carbon isotopic composition of alkane gas in large gas fields in China
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作者 DAI Jinxing NI Yunyan +4 位作者 GONG Deyu HUANG Shipeng LIU Quanyou HONG Feng ZHANG Yanling 《Petroleum Exploration and Development》 SCIE 2024年第2期251-261,共11页
Exploration and development of large gas fields is an important way for a country to rapidly develop its natural gas industry.From 1991 to 2020,China discovered 68 new large gas fields,boosting its annual gas output t... Exploration and development of large gas fields is an important way for a country to rapidly develop its natural gas industry.From 1991 to 2020,China discovered 68 new large gas fields,boosting its annual gas output to 1925×108m3in 2020,making it the fourth largest gas-producing country in the world.Based on 1696 molecular components and carbon isotopic composition data of alkane gas in 70 large gas fields in China,the characteristics of carbon isotopic composition of alkane gas in large gas fields in China were obtained.The lightest and average values ofδ^(13)C_(1),δ13C2,δ13C3andδ13C4become heavier with increasing carbon number,while the heaviest values ofδ^(13)C_(1),δ13C2,δ13C3andδ13C4become lighter with increasing carbon number.Theδ^(13)C_(1)values of large gas fields in China range from-71.2‰to-11.4‰(specifically,from-71.2‰to-56.4‰for bacterial gas,from-54.4‰to-21.6‰for oil-related gas,from-49.3‰to-18.9‰for coal-derived gas,and from-35.6‰to-11.4‰for abiogenic gas).Based on these data,theδ^(13)C_(1)chart of large gas fields in China was plotted.Moreover,theδ^(13)C_(1)values of natural gas in China range from-107.1‰to-8.9‰,specifically,from-1071%o to-55.1‰for bacterial gas,from-54.4‰to-21.6‰for oil-related gas,from-49.3‰to-13.3‰for coal-derived gas,and from-36.2‰to-8.9‰for abiogenic gas.Based on these data,theδ^(13)C_(1)chart of natural gas in China was plotted. 展开更多
关键词 china large gas field bacterial gas oil-related gas coal-derived gas abiogenic gas alkane gas carbon isotopic composition δ^(13)C_(1)chart
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口蹄疫病毒Asia1/JS/China/2005株基因组全长感染性克隆的构建 被引量:4
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作者 李平花 白兴文 +6 位作者 卢曾军 孙普 郭建宏 曹伟军 刘湘涛 殷宏 刘在新 《畜牧兽医学报》 CAS CSCD 北大核心 2009年第5期706-711,共6页
利用长距离RT-PCR技术扩增病毒基因组3′端覆盖口蹄疫病毒Asia1/JS/China/2005株近全长的3个片段(共约7.5 kb),并利用单一酶切位点将其分别克隆到pBluescriptSK+载体上。利用融合PCR扩增到基因组5′端含有15个C碱基的基因片段(约700 bp)... 利用长距离RT-PCR技术扩增病毒基因组3′端覆盖口蹄疫病毒Asia1/JS/China/2005株近全长的3个片段(共约7.5 kb),并利用单一酶切位点将其分别克隆到pBluescriptSK+载体上。利用融合PCR扩增到基因组5′端含有15个C碱基的基因片段(约700 bp),并将其连接至pGEM-T载体。最后将这4个片段的阳性克隆装配至剔除T7启动子的低拷贝载体pcDNA3.1/Zeo(+)中构建该病毒株的全长cDNA克隆。以构建的FMDV Asia1/JS/China/2005株全长cDNA为模板,使用T7RNA聚合酶在体外转录得到病毒RNA,通过脂质体将其导入BHK细胞获得拯救病毒。对收获的病毒分别用RT-PCR、间接免疫荧光、电子显微镜观察和乳鼠致病性分析结果证实,通过体外转录获得了具有感染性的口蹄疫病毒。该株感染性克隆的构建为深入研究口蹄疫病毒的致病机制及研制新型疫苗等奠定了基础。 展开更多
关键词 口蹄疫病毒 Asia1/JS/china/2005株 全长CDNA 转录物RNA 病毒拯救
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The HY-1 satellite and ground system in China 被引量:6
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作者 Liu Jianqiang , Jiang Xingwei, Lin Mingsen National Satellite Ocean Application Service of State Oceanic Administration, Beijing 100081, China, 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2003年第2期301-308,共8页
INTRODUCTIONWith the coming of the 21st century, we are faced the problems of the environment, re-sources and population. The ocean is regarded as supplier of resources such as food, minerals,energy and space, and pla... INTRODUCTIONWith the coming of the 21st century, we are faced the problems of the environment, re-sources and population. The ocean is regarded as supplier of resources such as food, minerals,energy and space, and plays an important role in sustainable economic development. At thesame time the ocean has a very important effect on the worldwide environmental changes. 展开更多
关键词 HY-1 satellite ground system china
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Occurrence of Aflatoxin B_(1),deoxynivalenol and zearalenone in feeds in China during 2018-2020 被引量:14
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作者 Ling Zhao Lei Zhang +5 位作者 Zijian Xu Xingda Liu Liyuan Chen Jiefan Dai Niel Alexander Karrow Lvhui Sun 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2022年第1期197-208,共12页
Background:The current study was conducted to investigate the individual and combined occurrence of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON)and zearalenone(ZEN)in feeds from various Provinces of China during 2018 ... Background:The current study was conducted to investigate the individual and combined occurrence of aflatoxin B_(1)(AFB_(1)),deoxynivalenol(DON)and zearalenone(ZEN)in feeds from various Provinces of China during 2018 to 2020.A total of 3,507 feed samples,including 2,090 feed ingredients and 1,417 complete feed samples,were collected from different areas of China for mycotoxins analysis.Results:The individual contamination of AFB_(1),DON and ZEN were present in more than 81.9%,96.4% and 96.9% of feed samples,respectively,with average concentration ranges of AFB_(1) between 1.2-27.4μg/kg,DON between 458.0-1,925.4μg/kg and ZEN between 48.1-326.8μg/kg.Notably,0.9%,0.5% and 0.1% of feed ingredients,and 1.2-12.8%,0.9-2.9% and 0-8.9% of complete feeds for pigs,poultry and ruminants with AFB_(1),ZEN and DON that exceeded China’s safety standards,respectively.Moreover,more than 81.5%of feed ingredients and 95.7% of complete feeds were co-contaminated with various combinations of these mycotoxins.Conclusion:This study indicates that the feeds in China were universally contaminated with AFB_(1),DON and ZEN during the past 3 years.These findings highlight the significance of monitoring mycotoxin contaminant levels in the domestic animal feed,and the importance of carrying out feed administration and remediation strategies for mycotoxin control. 展开更多
关键词 Aflatoxin B_(1) china DEOXYNIVALENOL Feeds ZEARALENONE
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21世纪以来中阿经贸合作发展的多维透视
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作者 王猛 王博超 《阿拉伯世界研究》 北大核心 2023年第1期25-49,158,159,共27页
在2001年至2021年间,中国与阿拉伯国家的经贸合作实现了跨越式发展,双边货物贸易额快速增长,贸易结构稳定,沙特和阿联酋等重点市场持续发挥着领头羊作用。能源联系始终是中阿经贸合作发展的主轴,中国即将到来的能源消费峰值可能削弱中... 在2001年至2021年间,中国与阿拉伯国家的经贸合作实现了跨越式发展,双边货物贸易额快速增长,贸易结构稳定,沙特和阿联酋等重点市场持续发挥着领头羊作用。能源联系始终是中阿经贸合作发展的主轴,中国即将到来的能源消费峰值可能削弱中阿经贸的增长推力,但基于巨量油气进口的能源联系对中阿经贸合作的推动作用还将持续。除了阿联酋、利比亚和阿尔及利亚以外,中国对阿拉伯产油国都持有巨额逆差,对非产油国持有巨额顺差。中阿经贸合作整体平衡与个体失衡的背后是中国商贸产品的较短产业链和较低附加值。基础设施建设和相互直接投资是中阿经贸“1+2+3”合作格局的两翼,前者发展相对较快,后者则一直在低位徘徊。未来的发展方向是推动阿拉伯国家的工业园区建设,强化中阿在核能、航天、卫星、新能源等高新领域的合作,建立中阿能源命运共同体。 展开更多
关键词 中阿经贸 1+2+3”合作格局 能源联系 基础设施建设 相互直接投资
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Preliminary observation results of the Coherent Beacon Systemonboard the China Seismo-Electromagnetic Satellite-1 被引量:4
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作者 Liang Chen Ming Ou +3 位作者 YaPing Yuan Fang Sun Xiao Yu WeiMin Zhen 《Earth and Planetary Physics》 2018年第6期505-514,共10页
This paper reports, for the first time, observation results of the Coherent Beacon System(CBS) onboard the China SeismoElectromagnetic Satellite-1(CSES-1). We describe the CBS, and the Computerized Ionospheric Tomogra... This paper reports, for the first time, observation results of the Coherent Beacon System(CBS) onboard the China SeismoElectromagnetic Satellite-1(CSES-1). We describe the CBS, and the Computerized Ionospheric Tomography(CIT) algorithm program is validated by numerical experiment. Two examples are shown, for daytime and nighttime respectively. The Equatorial Ionization Anomaly(EIA) can be seen, and the northern crest core is located at ~20°N in the reconstruction image at 07:28 UTC on 20 July 2018(daytime).Disturbances are shown in the reconstruction image at 18:40 UTC on 13 July 2018(nighttime). We find that beacon measurements are more consistent with ionosonde measurements than model results, by comparing Nm F2 at three sites at Lanzhou, Chongqing, and Kunming; consistency with ionosonde measurements validates beacon measurements. Finally, we have studied Vertical Total Electron Content(VTEC) variations from ground to ~500 km(the height of CSES-1 orbit) and ratios of VTEC between beacon measurements and CODE(Center for Orbit Determination in Europe) data. VTEC variation from ground to ~500 km has a range of 7.2–16.5 TECU for the daytime case and a range of 1.1–1.7 TECU for the nighttime case. The Beacon/CODE ratio of VTEC varies with latitude and time. The mean Beacon/CODE ratio is 0.69 for the daytime case and 0.26 for the nighttime case. The fact that the nighttime case yields lower ratios indicates the higher altitude of the ionosphere during nighttime when the ionosphere is assumed to be a thin layer. 展开更多
关键词 Coherent Beacon System(CBS) china Seismo-Electromagnetic Satellite-1(CSES-1) Computerized Ionospheric Tomography(CIT) Total Electron Content(TEC)
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The Influence of Climate Change on Winter Wheat during 2012-2100 under A2 and A1B Scenarios in China 被引量:4
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作者 SONG Yan-Ling CHEN De-Liang +1 位作者 LIU Yan-Ju XU Ying 《Advances in Climate Change Research》 SCIE 2012年第3期138-146,共9页
By assuming constant winter wheat varieties and agricultural practices in China, the influence of climate change on winter wheat is simulated using the corrected future climate projections under SRES A2 and A1B scenar... By assuming constant winter wheat varieties and agricultural practices in China, the influence of climate change on winter wheat is simulated using the corrected future climate projections under SRES A2 and A1B scenarios from 2012 to 2100, respectively. The results indicate that the growth of winter wheat would be strongly influenced by climate change in future. The average flowering and maturity dates of winter wheat would advance by 26 and 27 days under scenario A2, and by 23 and 24 days respectively under scenario A1B from 2012 to 2100. The simulated potential productivity of winter wheat shows a decrease of 14.3% and 12.5% for scenarios A2 and A1B respectively without the fertilization effect of CO2, while an increase of 1.3% and 0.6% with the fertilization effect of CO2. Additionally, for northern China, the simulated potential productivity would markedly decrease under both scenarios, independent with the fertilization effect of CO2, which indicates that the current planted winter wheat would be more vulnerable than that in southern China. The most likely reason is the current winter wheat varieties in northern China are winter varieties or strong winter varieties, which need some days of low temperature for dormancy. While in southern China, the winter wheat is spring or half winter varieties and can grow slowly during winter, thus, they would be affected slightly when winter temperature increases. The results of this study may have important implications for adaptation measures. 展开更多
关键词 climate change A2 and A1B scenarios WOFOST winter wheat china
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A Newly Discovered Oil-bearing Mesoproterozoic Erathem within the Niu D1 Well, Liaoxi Depression, Yanliao Faulted Depression Zone, NE China 被引量:3
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作者 SUN Qiushi GAO Xiaoyong +5 位作者 ZONG Wenming SUN Shouliang ZHANG Tao XIAO Fei LI Yongfei SHI Lei 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2020年第1期202-203,共2页
Objective The Yanshan Fold Belt is located within the northern margin of the North China platform and contains welldeveloped and widespread Neoproterozoic and Mesoproterozoic sedimentary units with a total thickness o... Objective The Yanshan Fold Belt is located within the northern margin of the North China platform and contains welldeveloped and widespread Neoproterozoic and Mesoproterozoic sedimentary units with a total thickness of up to 9000 m.Previous studies identified many oil seedlings as well as asphalt and ancient hydrocarbon reservoirs in Northern Hebei depression and western Liaoning depression.This research indicates that the Mesoproterozoic and Neoproterozoic sedimentary units are ideally suited for the formation of significant oil and gas resources.The Niu D1 well was drilled by the China Geological Survey(CGS)in the Niuyingzi area and intercepted oil immersions and oil-and gas-bearing units within a limestone reservoir in the middle Proterozoic Gaoyuzhuang Formation(Fig.1).This study presents new biomarker compound and carbon isotope data that indicate that the oil within this formation was derived from hydrocarbon source rocks of the Hongshuizhuang Formation,part of the Mesoproterozoic Jixian Series,and the reservoir type is overthrust fault fractured anticline hydrocarbon reservoir.The oil reservoir within the Gaoyuzhuang Formation limestone might represent the oldest oil reservoir discovered to date within the Yanliao faulted depression zone. 展开更多
关键词 NE china A NEWLY Discovered Oil-bearing MESOPROTEROZOIC Erathem within the Niu D1 WELL Yanliao Faulted DEPRESSION ZONE Liaoxi DEPRESSION
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Prevalence and patterns of drug-resistance mutations among HIV-1 patients infected with CRF07_BC strains in Sichuan province,China 被引量:1
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作者 Ling Su Xia Zhou +4 位作者 Dan Yuan Hong Yang Dongbing Wei Guangmin Qin Shu Liang 《Virologica Sinica》 SCIE CAS CSCD 2014年第4期237-241,共5页
Little information is available on the prevalence of drug-resistance mutations in patients harboring the human immunodeficiency virus type 1(HIV-1) circulating recombinant form(CRF)07_BC variant in Sichuan, China. Thi... Little information is available on the prevalence of drug-resistance mutations in patients harboring the human immunodeficiency virus type 1(HIV-1) circulating recombinant form(CRF)07_BC variant in Sichuan, China. This study examined 375 plasma samples from patients with HIV-1 who were infected with the CRF07_BC strain, including 104 drug-naive participants and 271 in whom antiretroviral therapy(ART) had failed. Only one participant in the drug-naive group had a drug-resistance mutation(M46L), compared with 31.73% of those in whom ART had failed. Further analysis showed that 19.56% of strains contained mutations conferring resistance to non-nucleoside reverse transcriptase inhibitors(NNRTIs) alone, 0.74% were resistant to nucleoside reverse transcriptase inhibitors(NRTIs) alone, and 11.44% were dual-resistant to both NRTIs and NNRTIs. The most common mutation in the ART-failure group was M184V(35.88%), K103N(45.01%), Y181C(17.33%), and G190S/A(15.88%). The percentages of HIV-1 strains resistant to lamivudine, emtricitabine, efavirenz, etravirine, and nevirapine were 10.70%, 10.70%, 28.04%, 7.75%, and 26.20%, respectively. To explore site variants possibly related to drug resistance, variations in the ancestor/consensus CRF07_BC sequences from the therapy-naive and ART-failure groups were compared, and seven mutations at six positions were identified as being significantly differently distributed between the two groups(p<0.05). Detailed sequence data will provide information on CRF07_BC genetic characterizations, and improve our understanding of antiretroviral susceptibility and the evolution of drug-resistance mutations. This will be valuable in developing and implementing local public-health approaches for HIV drug-resistance prevention and treatment. 展开更多
关键词 HIV-1 CRF07_BC drug resistance SICHUAN china
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OFD1 mutation induced renal failure and polycystic kidney disease in a pair of childhood male twins in China 被引量:3
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作者 Hong-Wen Zhang Bai-Ge Su Yong Yao 《World Journal of Clinical Cases》 SCIE 2020年第2期331-336,共6页
BACKGROUND Oral-facial-digital syndrome type 1(OFD1) is a rare ciliopathy mainly with an Xlinked dominant pattern of inheritance, which is caused by mutations in the OFD1 gene. The OFD1 protein is located within the c... BACKGROUND Oral-facial-digital syndrome type 1(OFD1) is a rare ciliopathy mainly with an Xlinked dominant pattern of inheritance, which is caused by mutations in the OFD1 gene. The OFD1 protein is located within the centrosomes and basal bodies of the primary cilia. It is reported that approximately 15%–50% cases of OFD1 progress to end-stage renal disease(ESRD) following development of polycystic kidney diseases(PKD). Here we report a pair of childhood male twins who presented only renal failure and PKD caused by an OFD1 mutation in China.CASE SUMMARY A pair of 14-year male twins were hospitalized with a complaint of abnormal renal function for nine days. They both complained of ankle pain for 3 mo vs 2 wk, respectively. They denied fever, abdominal pain, daytime or nighttime enuresis, urgency, dysuria, or gross hematuria. Laboratory tests at a local hospital showed renal failure(serum creatinine 485 μmol/L vs 442 μmol/L, blood urea nitrogen 14.7 mol/L vs 14.5 mol/L) and anemia(hemoglobin 88 g/L vs 98 g/L).The twins are monozygotic. There was no abnormal birth, past medical, or family history. Clinical data were analyzed and genetic analysis on PKD was carried out in the twins by next-generation sequencing. The results showed that the twins presented low-molecular-weight proteinuria, hyposthenuria, anemia, renal failure, and renal polycystic changes. Genetic tests showed that the twins both carried a hemizygous mutation in exon 19 c.2524 G>A(p. G842 R) of the OFD1 gene. Their mother heterozygously carried the same mutation as the twins but was without any phenotypes while their father was normal.CONCLUSION We have reported a pair of childhood male twins with an OFD1 mutation who presented ESRD and PKD but without any other phenotypes of OFD1 in China. 展开更多
关键词 Renal failure Polycystic kidney disease OFD1 mutation china Case report
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气象条件对廉玉1号玉米产量的影响 被引量:5
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作者 王俊方 周广胜 +1 位作者 宋艳玲 任三学 《应用气象学报》 CSCD 北大核心 2023年第3期373-378,共6页
厘清气象条件对玉米产量影响是确保玉米稳产高产的基础。基于2018—2021年河北固城农业气象国家野外科学观测研究站廉玉1号玉米不同播种期的田间试验对气象条件影响玉米产量的分析表明:播种期推迟导致发育期延长,改变发育期的气象条件... 厘清气象条件对玉米产量影响是确保玉米稳产高产的基础。基于2018—2021年河北固城农业气象国家野外科学观测研究站廉玉1号玉米不同播种期的田间试验对气象条件影响玉米产量的分析表明:播种期推迟导致发育期延长,改变发育期的气象条件。廉玉1号玉米播种期推迟20 d较提前10 d的平均发育期长度延长2.5 d,出苗-拔节期平均气温增加0.7℃,乳熟-成熟期平均气温减少5.9℃。玉米单产总体随播种期推迟呈降低趋势,6月8—18日期间播种可获得较高产量。出苗-拔节期的气温日较差以及抽雄-乳熟期的平均气温是影响廉玉1号玉米单产的关键气象因子。 展开更多
关键词 华北地区 廉玉1 播种期 产量 气象条件
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Characterization of Class 1 Integron Gene Cassettes among Clinical Bacteria Isolated from One Large Hospital in Northern China 被引量:5
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作者 CHEN Xia LI Gui Xi +4 位作者 ZHANG Hong YUAN Min HOU Xiao Ping YU Hui Lan LI Juan 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2013年第12期1003-1007,共5页
The class 1 integron and complex gene cassettes among different species of clinical isolates in northern China were characterized in this study. 383 clinical isolates were obtained from northern China, and class 1 int... The class 1 integron and complex gene cassettes among different species of clinical isolates in northern China were characterized in this study. 383 clinical isolates were obtained from northern China, and class 1 integrons containing gene cassettes widely distributed among gram negative clinical isolates was observed. We find that the class 1 integron showed positive correlation with multidrug resistance phenotype of gram negative bacteria. In addition, we find that isolates belonged to one species harbored different types of gene cassette arrays, while same types of gene cassette arrays were observed in different species of isolates. The diversity of gene cassette arrays among the isolates indicated the complexity of multidrug resistance in clinical isolates in northern China. 展开更多
关键词 gene Characterization of Class 1 Integron Gene Cassettes among Clinical Bacteria Isolated from One Large Hospital in Northern china
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The 1st International Conference on Datadriven Knowledge Discovery:When Data Science Meets Information Science.June 19–22,2016,Beijing·China 被引量:1
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作者 the jdis editors 《Journal of Data and Information Science》 2016年第3期1-5,共5页
The 1st International Conference on Data-driven Knowledge Discovery: When Data Science Meets Information Science took place at the National Science Library (NSL), Chinese Academy of Sciences (CAS) in Beijing from... The 1st International Conference on Data-driven Knowledge Discovery: When Data Science Meets Information Science took place at the National Science Library (NSL), Chinese Academy of Sciences (CAS) in Beijing from June 19 till June 22, 2016. The Conference was opened by NSL Director Xiangyang Huang, who placed the event within the goals of the Library, and lauded the spirit of intemational collaboration in the area of data science and knowledge discovery. The whole event was an encouraging success with over 370 registered participants and highly enlightening presentations. The Conference was organized by the Journal of Data andlnformation Science (JDIS) to bring the Joumal to the attention of an international and local audience. 展开更多
关键词 DATA BEIJING china The 1st International Conference on Datadriven Knowledge Discovery
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