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China-Africa Ties: A Brighter Future
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《ChinAfrica》 2018年第1期2-2,共1页
When China launched the first com-munication satellite for Algeria on December 11,it marked a milestone in joint aerospace cooperation be-tween the two countries.Fired from the Xichang Satellite Launch Center in south... When China launched the first com-munication satellite for Algeria on December 11,it marked a milestone in joint aerospace cooperation be-tween the two countries.Fired from the Xichang Satellite Launch Center in southwest China’s Sichuan Province,the sate-llite will be used for a variety of purposes,inclu-ding television broadcast,e-governance,and broadband access.It’s a demonstration of how far 展开更多
关键词 A Brighter Future china-africa ties
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益母草注射液通过其生物碱成分上调Tie-2、VEGFR2和VEGF促进斑马鱼血管新生
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作者 李玉芝 宋肖敏婷 +4 位作者 王雯雯 周欣雨 黎娅琳 任吉霞 曹治兴 《聊城大学学报(自然科学版)》 2024年第1期85-91,共7页
目的:研究益母草注射液在斑马鱼血管损伤模型中的促血管生成作用,并阐明潜在的物质基础和分子机制。方法:采用HPLC-PAD和TLC技术检测益母草注射液的主要成分;利用舒尼替尼诱导转基因Tg(flk1:eGFP)斑马鱼血管损伤模型,益母草注射液干预... 目的:研究益母草注射液在斑马鱼血管损伤模型中的促血管生成作用,并阐明潜在的物质基础和分子机制。方法:采用HPLC-PAD和TLC技术检测益母草注射液的主要成分;利用舒尼替尼诱导转基因Tg(flk1:eGFP)斑马鱼血管损伤模型,益母草注射液干预治疗后,测量斑马鱼节间血管(ISVs)长度,QT-PCR检测血管生成相关基因的表达水平。结果:发现益母草注射液的主要成分是水苏碱、胆碱和葫芦巴碱;其中,益母草注射液、葫芦巴碱和胆碱可减轻化学诱导的斑马鱼血管损伤,其作用机制涉及益母草注射液上调Tie-2、VEGF和VEGFR2的表达,其主要成分葫芦巴碱上调Tie-2和VEGF的表达,胆碱上调VEGF和VEGFR2的表达。结论:益母草注射液及其主要生物碱成分可通过上调Tie-2、VEGFR2和VEGF来促进血管生成。 展开更多
关键词 益母草注射液 血管生成 葫芦巴碱 胆碱 tie-2 VEGFR2 VEGF
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调控Ang/Tie信号通路治疗眼底新生血管性疾病的研究进展
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作者 杨婧研(综述) 魏文斌(审校) 《中华实验眼科杂志》 CAS CSCD 北大核心 2024年第5期467-472,共6页
抗血管内皮生长因子(VEGF)治疗应用于眼底新生血管疾病领域以来,在提高视力、稳定疾病病变和在某些情况下逆转疾病方面显示了卓越的效果。但抗VEGF治疗需要频繁玻璃体内注射给药,患者治疗负担重,长期疗效受影响。前期临床研究发现,调控... 抗血管内皮生长因子(VEGF)治疗应用于眼底新生血管疾病领域以来,在提高视力、稳定疾病病变和在某些情况下逆转疾病方面显示了卓越的效果。但抗VEGF治疗需要频繁玻璃体内注射给药,患者治疗负担重,长期疗效受影响。前期临床研究发现,调控血管生成素(Ang)/含免疫球蛋白样环和上皮生长因子样域酪氨酸激酶(Tie)通路在眼底新生血管疾病的治疗中有较好的效果。目前已发布了3个Ang/Tie通路阻断药物治疗眼底新生血管疾病的临床研究数据,其中靶向VEGF-A和Ang-2的双特异性免疫球蛋白G1抗体faricimab进入了Ⅲ期临床试验并达到终点,faricimab的2种延长治疗间隔(12周和16周)的给药方案均被证实有效。本文基于已发表的研究报告,就调控Ang/Tie通路在眼底新生血管性疾病治疗中的作用及临床应用作一综述,总结分析Ang/Tie通路的作用机制以及未来药物的应用前景。 展开更多
关键词 眼底新生血管疾病 抗新生血管生成 Ang/tie通路
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Effects of anti-pull ties on the bearing behaviors of shallow tunnel-type anchorages in soft rock
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作者 HAN Ya-feng LIU Xin-rong +5 位作者 ABI Erdi TU Yi-liang XU Bin ZHOU Xiao-han DENG Zhi-yun WANG Zhong-hao 《Journal of Mountain Science》 SCIE CSCD 2023年第9期2708-2730,共23页
Tunnel-type anchorages(TTAs)installed in human gathering areas are characterized by a shallow burial depth,and in many instances,they utilize soft rock as the bearing stratum.However,the stability control measures and... Tunnel-type anchorages(TTAs)installed in human gathering areas are characterized by a shallow burial depth,and in many instances,they utilize soft rock as the bearing stratum.However,the stability control measures and the principle of shallow TTAs in soft rock have not been fully studied.Hence,a structure suitable for improving the stability of shallow TTAs in soft rock strata,named the anti-pull tie(APT),was added to the floor of the back face.Physical tests and numerical models were established to study the influence of the APT on the load transfer of TTAs,the mechanical response of the surrounding rock,the stress distribution of the interface,and the failure model.The mechanical characteristics of APTs were also studied.The results show that the ultimate bearing capacity of TTAs with an APT is increased by approximately 11.8%,as compared to the TTAs without an APT.Also,the bearing capacity of TTAs increases approximately linearly with increasing height,width,length,and quantity of APTs,and decreases approximately linearly with increasing distance from the back face and slope angle of the tie slope.The normal squeezing between the tie slope and the surrounding rock increases the shear resistance of the interface and expands the range of the surrounding rock participating in bearing sharing.Both tension and compression zones exist in the APT during loading.The tension zone extends from the tie toe to the tie bottom along the tie slope.The range of the tie body tension zone constantly expands to the deep part of the APT with an increasing load.The peak tensile stress value is located at the tie toe.The distribution of compressive stress in the tie body is the largest at the tie top,followed by the tie slope,and then the tie bottom. 展开更多
关键词 Shallow tunnel-type anchorage Soft rock Anti-pull tie Bearing behaviors Stability control measures
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A SYMBOL OF STRONG CHINA-INDONESIA TIES
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作者 Yuan Yanan 《China Report ASEAN》 2023年第10期34-35,共2页
“The Jakarta-Bandung High-Speed Railway(HSR)is a crucial achievement in practical cooperation between China and Indonesia,”said Paulus Rudolf Yuniarto,a researcher at the Indonesia National Research and Innovation A... “The Jakarta-Bandung High-Speed Railway(HSR)is a crucial achievement in practical cooperation between China and Indonesia,”said Paulus Rudolf Yuniarto,a researcher at the Indonesia National Research and Innovation Agency. 展开更多
关键词 cooperation Jakarta tie
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浅谈TIE-固定篦床的优化升级
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作者 游磊 余先林 +4 位作者 邢涛 杨腾飞 郝帅起 徐一源 李福祥 《新世纪水泥导报》 CAS 2024年第2期16-19,I0013,共5页
TIE-固定篦床采用中心分区供风、微调风阀、水滴型高效篦板等技术,用水平出风的高速气流快速急冷熟料,不仅系统可获得温度较高且稳定的二次风,还能均布熟料,减少粗细熟料的离析分布,从源头上控制“红河”的产生;在稳定较高的二次风温下... TIE-固定篦床采用中心分区供风、微调风阀、水滴型高效篦板等技术,用水平出风的高速气流快速急冷熟料,不仅系统可获得温度较高且稳定的二次风,还能均布熟料,减少粗细熟料的离析分布,从源头上控制“红河”的产生;在稳定较高的二次风温下,还可将料层厚度总体降低至650mm左右,大幅减小后续所有冷却风机的总体负载阻力,进一步有利于熟料的冷却和降低冷却电耗。实践表明,使用TIE-固定篦床局部替换旧的固定篦床,能有效地提高二次风温,降低烧成系统的能耗,还可显著提高熟料的质量。 展开更多
关键词 tie-固定篦床 水滴型高效篦板 熟料急冷 PLUS篦冷机 节能降耗技改
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飞机风挡裂纹/破裂类事件统计及Bow-tie模型分析
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作者 刘俊杰 张晴 《科学技术与工程》 北大核心 2024年第7期3034-3042,共9页
为分析航空器风挡裂纹/破裂类事件的安全风险,收集1 629份风挡裂纹/破裂类事件,对样本事件涉及故障状况、飞行阶段、故障原因等特征进行统计分析,确定风挡裂纹/破裂类事件的可能原因、潜在后果及其预防、减缓控制措施并绘制了风挡裂纹/... 为分析航空器风挡裂纹/破裂类事件的安全风险,收集1 629份风挡裂纹/破裂类事件,对样本事件涉及故障状况、飞行阶段、故障原因等特征进行统计分析,确定风挡裂纹/破裂类事件的可能原因、潜在后果及其预防、减缓控制措施并绘制了风挡裂纹/破裂类事件Bow-tie模型图。结果表明:风挡损伤的主要情形包括裂开、裂缝、结冰、烟雾、划伤等;涉及风挡及相关部件故障以加温故障、雨刷故障为主;飞行阶段以巡航、爬升为主;风挡裂纹/破裂事件的主要原因为鸟击、零部件缺失/故障、系统失效/故障、冰击,最终有针对性地提出预防措施:机务、机组等相关人员应做好航前、航后检查;对零部件缺失/损坏/磨损、系统失效、鸟击等高发事件类型进行重点关注,提高机组人员对此类突发事件的应对能力等。 展开更多
关键词 航空安全 事件分析 风挡 鸟击 Bow-tie模型
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基于Bow-Tie的复杂场景保护层分析方法研究
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作者 金浩 汪宏 +1 位作者 李雁 赵积洲 《化肥设计》 CAS 2024年第2期8-13,35,共7页
为解决复杂场景保护层分析中采用最大值法或加和法存在的问题,将Bow-Tie融入LOPA分析中,建立复杂场景的Bow-Tie计算模型。通过采用事故树分析方法,计算Bow-Tie模型中顶上事件发生的概率,确定预防类保护层及减缓类保护层的失效概率,给出... 为解决复杂场景保护层分析中采用最大值法或加和法存在的问题,将Bow-Tie融入LOPA分析中,建立复杂场景的Bow-Tie计算模型。通过采用事故树分析方法,计算Bow-Tie模型中顶上事件发生的概率,确定预防类保护层及减缓类保护层的失效概率,给出了复杂场景事故发生概率合理的计算方法;通过计算Bow-Tie模型中事故树底事件的概率重要度和临界重要度,提出了判断复杂场景保护层重要度的方法。运用上述方法对某LNG储罐超压损坏的复杂场景进行了计算。研究表明,本方法能实现包含多重初始事件的复杂事故场景后果风险更合理的计算及保护层重要度的判定,从而为提高系统安全性及风险决策提供依据。 展开更多
关键词 保护层分析(LOPA) 领结图分析(Bow-tie) 事故树 复杂场景 风险计算
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基于改进Bow-tie模型的煤矿瓦斯爆炸事故分析与研究
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作者 侯玮 林倩 +1 位作者 马润泽 徐子怡 《煤炭与化工》 CAS 2024年第2期120-125,共6页
针对我国伤亡人数较多的采矿行业,对伤亡人数最多的瓦斯爆炸事故进行了分析,提出了改进Bow-tie模型。在原因辨识环节将瓦斯爆炸事故的原因归纳为人因、物因、环境、管理4个方面进行论述,利用屏障思维对主动屏障进行量化分级提出预防措施... 针对我国伤亡人数较多的采矿行业,对伤亡人数最多的瓦斯爆炸事故进行了分析,提出了改进Bow-tie模型。在原因辨识环节将瓦斯爆炸事故的原因归纳为人因、物因、环境、管理4个方面进行论述,利用屏障思维对主动屏障进行量化分级提出预防措施,通过模型分析事故可能产生的安全、经济、环境、社会后果,提出消减措施作为被动屏障,绘制改进Bow-tie图,并在此基础上运用层次分析进行评价分析。研究表明,管理体系欠缺以及人的不安全行为是导致事故发生的主要因素。 展开更多
关键词 煤矿 瓦斯爆炸事故 改进Bow-tie模型 屏障思维
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基于Bow-Tie模型和未确知测度理论的煤矿透水风险分析
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作者 侯玮 马润泽 +1 位作者 林倩 毕昊媛 《煤炭与化工》 CAS 2024年第1期110-114,共5页
为了克服煤矿井下透水事故安全性评价相关因子的不确定性,以及权重指标赋值模糊的问题,采用Bow-Tie模型分析法通过对煤矿井下的人、物、环境、管理4个方面的分析研究,建立出煤矿透水事故的Bow-Tie评价模型,把得到的12项透水事故的影响... 为了克服煤矿井下透水事故安全性评价相关因子的不确定性,以及权重指标赋值模糊的问题,采用Bow-Tie模型分析法通过对煤矿井下的人、物、环境、管理4个方面的分析研究,建立出煤矿透水事故的Bow-Tie评价模型,把得到的12项透水事故的影响因子作为煤矿透水事故风险评估的评价指标。通过层次分析法对指标进行权重的赋值,最后由未确知测度法确定煤矿透水事故风险评价等级。通过对小回沟煤矿进行实例评估分析,评价结果与该煤矿实际相符合,可见该法的合理性和适用性,可以为煤矿透水事故的风险评价提出一些指导。 展开更多
关键词 煤矿透水 Bow-tie模型 未确知测度理论 风险评价
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Critical role of risk management in ground engineering and opportunities for improvement 被引量:2
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作者 Jim Galvin 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2017年第5期725-731,共7页
Green mining is concerned with mining in a sustainable manner, such that the needs of the present are met without compromising future generations. The achievement of this objective depends on balancing social, environ... Green mining is concerned with mining in a sustainable manner, such that the needs of the present are met without compromising future generations. The achievement of this objective depends on balancing social, environmental and economic objectives and has to have regard to both active mining operations and legacy issues associated with mine closure. Ground engineering has a critical role in achieving green mining objectives but its contribution is characterised by pervasive uncertainty. Uncertainty equates to risk. This means that ground engineering should be practiced within a risk management framework that aims to both prevent unwanted outcomes and to mitigate their consequences to an acceptable level. This keynote address presents the fundamentals of risk management and demonstrates its effectiveness by reference to improvements in the safety performance of the NSW coal sector over the past three decades.Nevertheless, ground control remains a mix of art and science, relying heavily on judgements which should be premised on knowledge, skill and experience(that is, competence). Risk management has now been enshrined in mining legislation and operating practice in Australia for over two decades.Notwithstanding this, near-hit and accident and incident investigations, commissions of inquiry and legal proceedings almost invariably identify deficiencies and opportunities for improvements necessary to achieve the objectives of sustainable mining. Three of the more important opportunities which have global application in relation to ground engineering are discussed. These relate to the vexing issue of defining competency in ground engineering; the criteria for undertaking rigorous risk assessment; and the need for ground engineers to become involved in mine rehabilitation and closure planning over the full life cycle of a mine, commencing at the prefeasibility stage. 展开更多
关键词 BOW tie analysis MINE safety MINE CLOSURE RISK assessment RISK management Sustainable mining Uncertainty
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基于Ang1/Tie2信号通路研究周细胞调控腹膜血管新生的作用机制 被引量:1
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作者 黄丽嫣 唐蕾 +6 位作者 朱晓琳 单云 史俊 俞曼殊 孙谨怡 盛莉 盛梅笑 《中国病理生理杂志》 CAS CSCD 北大核心 2023年第5期884-892,共9页
目的:本研究旨在通过观察血管周细胞与血管内皮细胞间的相互作用,探讨周细胞调控腹膜血管新生的作用机制。方法:使用转化生长因子β1(TGF-β1)干预人微血管周细胞(HMPCs)24、48和96 h,Western blot检测HMPCs中血管生成素1(Ang1)的表达... 目的:本研究旨在通过观察血管周细胞与血管内皮细胞间的相互作用,探讨周细胞调控腹膜血管新生的作用机制。方法:使用转化生长因子β1(TGF-β1)干预人微血管周细胞(HMPCs)24、48和96 h,Western blot检测HMPCs中血管生成素1(Ang1)的表达。收集TGF-β1干预HMPCs后的上清液作为条件培养基(T-HMPCs-CM),用T-HMPCs-CM处理人腹膜血管内皮细胞(HPVECs)构建间接共培养模式;将TGF-β1处理过的HMPCs与HPVECs共同接种于基质胶上,构建直接共培养模式;以未经TGF-β1处理的HMPCs作为阴性对照组,以外源性Ang1处理的HPVECs作为阳性对照组,以人血管生成素受体Tie2抑制剂处理的HPVECs作为抑制剂组。采用CCK-8法、细胞划痕实验、Transwell实验、成管实验和细胞膜荧光探针染色法观察HPVECs增殖、迁移、血管生成情况,以及HPVECs与HMPCs共定位情况;Western blot检测HPVECs中Tie2蛋白及其磷酸化水平。结果:TGF-β1处理96 h,HMPCs中Ang1蛋白表达水平显著升高(P<0.01)。与阴性对照组相比,T-HMPCs-CM能够抑制HPVECs迁移、血管新生,并增加Tie2磷酸化以稳定血管状态,其作用类似于外源性Ang1;而使用Tie2抑制剂阻断Ang1/Tie2信号通路后,上述作用一定程度上被逆转。结论:TGF-β1可刺激HMPCs分泌Ang1,进而激活HPVECs的Tie2信号通路,从而抑制HPVECs血管新生,发挥维持腹膜血管稳定的作用。 展开更多
关键词 腹膜血管内皮细胞 血管新生 微血管周细胞 Ang1/tie2信号通路
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Measurement of vibration frequencies of ties in masonry arches by means of a robotic total station
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作者 Marco Gatti 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2022年第2期489-500,共12页
Measurement of the vibration frequencies of eight ties set in masonry arches of a church by means of a robotic total station is described.The instrument made continuous recordings(up to ten per second)of the three-dim... Measurement of the vibration frequencies of eight ties set in masonry arches of a church by means of a robotic total station is described.The instrument made continuous recordings(up to ten per second)of the three-dimensional positions of a reflector situated at 1/2 or 1/4 of the length of the tie during vertical oscillation induced by an impulsive load.The recording slips,vibration amplitudes(and their accuracy),hourly diagram and experimental spectra of vibrations,and the corresponding frequencies were calculated.The results were verified by comparing them with the vibration frequencies and indirectly the tension and fixed support constraint calculated from accelerometric measurements.The study provides interesting information on the accuracies of the reflector′s three-dimensional coordinates,but highlighted certain limits in the application of robotized total stations for measuring vibration frequencies of ties in masonry arches. 展开更多
关键词 RTS FREQUENCY vibrations ties ARCHES
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Post-Sept. -11 Sino-U. S. Ties
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作者 Yuan Peng Yuan Peng is Associate Research Professor and Deputy Director at Division for North and Latin American Studies, China Institute of Contemporary International Relations. 《Contemporary International Relations》 2001年第11期1-16,共16页
Like a big rock thrown into the pond of current international power configuration, the event of September 11 revealed the turbulent undercurrents beneath its seemingly tranquil surface. The splashdown effect has sprea... Like a big rock thrown into the pond of current international power configuration, the event of September 11 revealed the turbulent undercurrents beneath its seemingly tranquil surface. The splashdown effect has spread beyond the United States to reach every corner of our planet. It has triggered realignment in big power relations and will have its far- 展开更多
关键词 ties Post-Sept Sino-U
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Chinese,Portuguese Leaders Exchange Congratulations on 40th Anniversary of Diplomatic Ties
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《China Today》 2019年第3期6-6,共1页
Chinese President Xi Jinping and Portuguese President Marcelo Rebelo de Sousa on February 8 exchanged congratulations on the 40th anniversary of the establishment of China-Portugal diplomatic relations.
关键词 The establishment of diplomatic ties CHINESE PORTUGAL
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The Sign Test with Ties Included
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作者 Jennings B. Marshall 《Applied Mathematics》 2014年第10期1594-1597,共4页
The sign rank test is taught in virtually all introductory Statistics classes. When teaching the sign rank test the students are told to ignore the ties. Ignoring ties that support the null hypothesis is not logical. ... The sign rank test is taught in virtually all introductory Statistics classes. When teaching the sign rank test the students are told to ignore the ties. Ignoring ties that support the null hypothesis is not logical. Why should valid data that support the null hypothesis be ignored? The approach taken here demonstrates a method for testing with ties included. A typical problem presentation in a text book would indicate that if you had ten ties in a sample of size fifty the tie scores would be excluded. However, the ten tie scores are a very valuable piece of statistical information which should not be ignored. The method demonstrated here shows that a different conclusion is reached in some cases when the ties are not excluded. Further many sign tests often will have ties because in some cases the data are not a cardinal number, but an ordinal number chosen from a set often results in ties. The alternative approach uses a one-tailed distribution and considers both +’s and -'s separated. A two-tailed test for equal variances is done with a one-tail of an F distribution. This alternate approach to the sign test allows the use of important statistical information which has been ignored with the traditional sign rank test. 展开更多
关键词 SIGN TEST ties
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Ponder over the Changes in Sino-Russian-U. S. Ties
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作者 Xing Guangcheng 《Contemporary International Relations》 2003年第6期8-12,共5页
Some changes have indeed taken place in international situation from September 11 to Iraq war. Changes in big power relations in particular have given food for thought. Today Ⅰ would like to focus on the changes in t... Some changes have indeed taken place in international situation from September 11 to Iraq war. Changes in big power relations in particular have given food for thought. Today Ⅰ would like to focus on the changes in the relations among China, Russia and the United States as well as my consideration of China’s diplomacy. 展开更多
关键词 in on ties Ponder over the Changes in Sino-Russian-U OVER
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Xi Meets European Leaders on Advancing Ties, Global Governance
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《China Today》 2019年第5期6-6,共1页
Chinese President Xi Jinping, French President Emmanuel Macron, German Chancellor Angela Merkel and European Commission President Jean- Claude Juncker met in Paris on March 26 and agreed to strengthen China-European U... Chinese President Xi Jinping, French President Emmanuel Macron, German Chancellor Angela Merkel and European Commission President Jean- Claude Juncker met in Paris on March 26 and agreed to strengthen China-European Union (EU) relations and global governance cooperation. 展开更多
关键词 XI Meets EUROPEAN LEADERS Advancing ties
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The US Enhancing Ties with Sri Lanka: Motivations and Restraints
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作者 Li Yibo 《China International Studies》 2019年第4期98-112,共15页
As the Trump administration promotes its Indo-Pacific strategy in a very high-profile manner, the position of South Asia in the US foreign strategy has been growing in importance, which has led to an elevation of rela... As the Trump administration promotes its Indo-Pacific strategy in a very high-profile manner, the position of South Asia in the US foreign strategy has been growing in importance, which has led to an elevation of relations between the US and many countries in the region. In particular, the development of US-Sri Lanka relationship is worth reviewing, not only because it sets an example of growing relations between the US and small "Indo-Pacific" countries, but also because it will bring new variables to the security situation in the Bay of Bengal and the Indian Ocean. 展开更多
关键词 The US ENHANCING ties SRI Lanka MOTIVATIONS and RESTRAINTS
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China's WTO Entry Helps Sino-US Ties
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作者 蒋裕国 《Contemporary International Relations》 2000年第9期1-10,共10页
China applied for restoration of its status as the GATT founding member in1986. The country has made great endeavor in reducing customs duties, removing non-tariff barriers, enhancing protection of intellectual proper... China applied for restoration of its status as the GATT founding member in1986. The country has made great endeavor in reducing customs duties, removing non-tariff barriers, enhancing protection of intellectual property rights andservice trades, launching reform of the foreign trade regime, eliminating trade bar-riers and improving environment for foreign investment. Over the past 14 years,China has taken part in 26 relevant multilateral meetings and hundreds of bilateralnegotiations. 展开更多
关键词 WTO WILL China’s WTO Entry Helps Sino-US ties US
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