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Integrated Development of Chinese Herbal Medicine Planting and Tourist Commodities: A Case Study of Green Handmade Soap Development in Shandong Province
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作者 Xiu LI Mengxuan CHEN Xiaoli SONG 《Asian Agricultural Research》 2015年第5期82-84,共3页
Combining current situations of Chinese herbal medicine planting industry in Shandong,in line with existing problems of Chinese herbal medicine planting industry,this paper analyzed development prospect of tourist com... Combining current situations of Chinese herbal medicine planting industry in Shandong,in line with existing problems of Chinese herbal medicine planting industry,this paper analyzed development prospect of tourist commodity industry in Shandong Province,and came up with actual selection and recommendations for integrated development of Chinese herbal medicine planting and tourist commodities. 展开更多
关键词 chinese herbal medicine plantING industry TOURIST
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Extraction of Essential Oils from Afghanistan Medicinal Plants Using Microwave and Conventional Methods
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作者 Nazifa Faqeryar Yoshihito Mori 《Journal of Pharmacy and Pharmacology》 2018年第3期202-216,共15页
Afghanistan has many kinds of volatile-off-rich and not-fully-utilized flora. This article represents a review on Afghanistan medicinal plants contain essential oils. Lamiaceae, Asteraceae and Apiaceae are the most im... Afghanistan has many kinds of volatile-off-rich and not-fully-utilized flora. This article represents a review on Afghanistan medicinal plants contain essential oils. Lamiaceae, Asteraceae and Apiaceae are the most important botanical families which are widely found and used as traditional medicines, food and spices in Afghanistan. Over 215 plants which are used in traditional therapy in Afghanistan, 93 plants contain essential oils. Twenty-two plants contain essential oils applied to microwave extraction techniques and forty-nine plants contain essential oils applied to conventional extraction techniques. Totally 41 extracted species belong to above mentioned botanical families that could be found in Afghanistan too. But still there are some species of these families which are endemic in Afghanistan and not studied yet. 展开更多
关键词 Afghanistan medicinal plants essential oils conventional extraction microwave extraction.
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Essential oil yield and composition of four annual plants(ajowan,dill,moldavian balm and black cumin)under saline irrigation
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作者 Saeid Davazdahemami Marziyeh Allahdadi 《Food Therapy and Health Care》 2022年第1期16-24,共9页
Background:Ajowan,dill,moldavian balm and black cumin are annual medicinal plants,essential oil bearing that are cultivated in different parts of the world.Methods:A field experiment was conducted to assess the essent... Background:Ajowan,dill,moldavian balm and black cumin are annual medicinal plants,essential oil bearing that are cultivated in different parts of the world.Methods:A field experiment was conducted to assess the essential oil of ajowan,dill,moldavian balm and black cumin under salinity of 0.3,3,6 and 9 dS/m NaCl.Essential oils were obtained by using a Clevenger apparatus and their constituents were identified by GC and GC/MS.Results:Results showed that essential oil yield varied in tested plants under salt stress,but its changes did not follow a specific trend.Thymol was the most abundant constituent of ajowan seed essential oil,while thymol,γ-terpinene and p-cymene were the major constituents of the foliage essential oil of it.The most important component of dill seed essential oil was carvone and three main components of foliage essential oil were carvone,limonene andα-phellandrene.The essential oil component in moldavian balm mostly contained neral,geranial,geraniol,neryl acetate and geranyl acetate.The essential oil of black cumin was mainly composed of p-cymene under saline irrigation.Conclusion:The essential oil yield and compositions were affected by salt stress.The essential oil yield decreased because of decreasing dry biomass production. 展开更多
关键词 essential oil FOLIAGE GC/MS medicinal plants NaCl SEED
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Evaluation of the Essential Oil of <i>Citrus paradisi</i>as an Alternative Treatment against <i>Candida albicans</i>
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作者 Ameyalli J. Martinez Delgado Uziel Castillo Velázquez +5 位作者 Juan G. Báez González Abelardo Chávez Montes Sonia M. López Villarreal Laura Elena Villarreal García Rosa María Sánchez Casas Osvelia E. Rodríguez Luis 《Open Journal of Stomatology》 2020年第9期258-270,共13页
<strong>Introduction:</strong> The World Health Organization establishes that 80% of the world’s population uses traditional medicine for their primary care, because they contain compounds responsible for... <strong>Introduction:</strong> The World Health Organization establishes that 80% of the world’s population uses traditional medicine for their primary care, because they contain compounds responsible for their properties. <strong>Objective:</strong> To evaluate the antifungal effect of the essential oil of <i>Citrus paradisi<span style="white-space:nowrap;"></span></i> against <i>C. albicans<span style="white-space:nowrap;"></span></i> and the cytotoxic effect in three cell lines <em>in vitro</em>. <strong>Methods:</strong> The phytochemical characterization of the oil was carried out by chemical methods and Gas chromatography (GC-MS) and the antifungal effect against <i>C. albicans<span style="white-space:nowrap;"></span></i> (ATCC 90029) was evaluated by the Kirby-Bauer method, which evaluated concentrations of 0.75 - 20 μg/mL and compared with nystatin 100,000 Ul/mL as a positive control. The percentage of the relative inhibitory effect was calculated. The minimum inhibitory concentration (MIC) was determined at 24 hours. Moreover, the cytotoxic effect on <em>C. albicans</em> and cell lines was determined by the colorimetric MTT tetrazolium assay. Finally, the antifungal effect against <em>Candida</em> strains isolated from clinical samples was evaluated at a concentration of 20 μg/mL. <strong>Results:</strong> The essential oil showed an antifungal effect with a percentage of inhibition of 123%. The MIC was 2.5 μg/mL, and the cytotoxicity index was 5.44 μg/mL for <em>C. albicans</em>. The IC50 values were 21.060, 9.482 and 4.176 μg/mL for Vero E6, J774A.1 and MDBK cells respectively. <strong>Conclusion:</strong> These results show the use of <em>C. paradisi</em> essential oil as an alternative treatment in oral antifungal therapy, it is beneficial due to its antifungal effect and its low toxicity on cell cultures. 展开更多
关键词 Citrus Candida CANDIDIASIS essential oil herbal medicine
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Action of Essential Oils Obtained from Baccharis coridifolia D.C.(Asteraceae-Astereae)on the Activity of Antibiotics
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作者 Sideney Becker Onofre Marilde Canton Paula Andressa Pires 《Advances in Microbiology》 2013年第2期166-170,共5页
The aim of this study was to investigate the effects of Baccharis coridifolia essential oil on the Activity of Antibiotics. Assays were performed with ampicillin (10 μg), cephalothin (30 μg), chloramphenicol (30 μg... The aim of this study was to investigate the effects of Baccharis coridifolia essential oil on the Activity of Antibiotics. Assays were performed with ampicillin (10 μg), cephalothin (30 μg), chloramphenicol (30 μg), gentamicin (10 μg) and tetracycline (30 μg) alone and in combination with the essential oil (4% v/v) through the disk diffusion susceptibility test. The results showed the effects of essential oil on the activity of the antibiotics tested. Zones of inhibition of bacterial growth with different diameters were observed surrounding the antibiotic disks, whether or not they were impregnated with the essential oil. The occurrence of the synergistic or antagonistic effect was observed in both bacterial strains assessed—Staphylococcus aureus (ATCC-25923) and Escherichia coli (ATCC-25922). These results show that the use of products derived from plants can, in some cases, interfere with the effectiveness of antibiotics during clinical therapy. 展开更多
关键词 Medicinal plants essential oils Antibiotic Associated Use Interference
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芳香中药在动物健康养殖中的研究与应用 被引量:3
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作者 印遇龙 陶晋升 +3 位作者 白平 宋涛 黄鹏 杨哲 《饲料工业》 北大核心 2024年第1期2-9,共8页
多年来,动物生产中滥用抗生素等药物给人类健康带来了严重威胁,着眼于提高动物机体健康水平或将成为未来畜禽水产业可持续发展的方向。芳香中药通常指以挥发性物质为主要有效成分具有芳香气味的中药材及其提取物,具有抗菌、抗炎、增强... 多年来,动物生产中滥用抗生素等药物给人类健康带来了严重威胁,着眼于提高动物机体健康水平或将成为未来畜禽水产业可持续发展的方向。芳香中药通常指以挥发性物质为主要有效成分具有芳香气味的中药材及其提取物,具有抗菌、抗炎、增强免疫等作用。近年来,很多研究都在探讨芳香中药作为饲用替抗产品的潜力,文章综述了芳香中药的作用机制及其动物生产中的研究进展,并分析了芳香中药与动物健康养殖的关系及芳香中药当前存在的问题,对其发展前景进行了展望。文章旨在总结芳香中药目前的研究状况,为芳香中药在畜禽、水产健康养殖及饲料工业等方面的研究提供参考意见。 展开更多
关键词 芳香中药 植物精油 替抗 畜禽 水产 健康养殖
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基于芳香中药探讨芳香疗法在偏头痛中的应用
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作者 汪耳迪 李霞 +1 位作者 伍睿昕 张洁 《香料香精化妆品》 CAS 2024年第4期32-37,共6页
偏头痛是一种常见的原发性头痛疾病,严重影响了人们的生活质量,加重了社会经济负担。但目前的治疗方法并不理想,存在药物不良反应、耐受性差等问题。芳香疗法是一种利用植物精油的气味来调节身心状态的替代疗法,在治疗偏头痛方面具有一... 偏头痛是一种常见的原发性头痛疾病,严重影响了人们的生活质量,加重了社会经济负担。但目前的治疗方法并不理想,存在药物不良反应、耐受性差等问题。芳香疗法是一种利用植物精油的气味来调节身心状态的替代疗法,在治疗偏头痛方面具有一定的作用和优势。综述了芳香疗法的基本原理及在偏头痛中的作用机制,介绍了几种常见中药芳香精油在偏头痛中的应用效果,同时将芳香疗法与其他非药物疗法联合应用,以期为偏头痛患者寻求一种创伤小、疗效好的辅助疗法,使其在临床实践中推广应用。 展开更多
关键词 芳香中药 芳香疗法 精油 偏头痛
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不同中草药植物提取物对香蕉枯萎病菌抑菌活性评价
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作者 黄永丰 项丹丹 +2 位作者 江振兴 李春雨 胡位荣 《广东农业科学》 CAS 2024年第3期48-55,共8页
【目的】探究不同中草药提取物对香蕉枯萎病菌的抑菌效果,筛选防治香蕉枯萎病的有效植物资源。【方法】选取大黄、穿心莲等29种中草药,采用乙醇浸提法提取中草药植物中的有效活性成分,应用生长速率法检测各提取物对香蕉枯萎病菌4号生理... 【目的】探究不同中草药提取物对香蕉枯萎病菌的抑菌效果,筛选防治香蕉枯萎病的有效植物资源。【方法】选取大黄、穿心莲等29种中草药,采用乙醇浸提法提取中草药植物中的有效活性成分,应用生长速率法检测各提取物对香蕉枯萎病菌4号生理小种(Foc TR4)的抑制作用,使用石油醚、氯仿、乙酸乙酯、正丁醇4种不同极性溶剂对大黄的乙醇粗提物进行分级萃取,利用悬滴法测定提取物对香蕉枯萎病菌孢子萌发的抑制作用,并观察提取物对香蕉枯萎病菌菌丝形态的影响。【结果】29种中草药提取物对Foc TR4的抑菌效果表现出较大差异,大黄、穿心莲、苦参、野菊花4种提取物对Foc TR4的抑菌效果较好,其中大黄提取物的抑制作用最佳,6 mg/mL大黄提取物的抑菌率为48.57%,对菌丝生长的EC_(50)值为6.68 mg/mL,抑制孢子萌发的EC_(50)值为4.60 mg/mL;通过光学显微镜观察,大黄提取物对Foc TR4菌丝具有一定破坏作用,使菌丝产生大量分枝和黏连并造成菌丝生长不均匀等现象;大黄乙醇粗提物的石油醚、氯仿、乙酸乙酯、正丁醇4个萃取组分中,乙酸乙酯萃取组分对Foc TR4菌丝生长和孢子萌发抑制效果最佳,其浓度为10 mg/mL时,对菌丝生长的抑制率可达85.68%;大黄提取物乙酸乙酯萃取组分对Foc TR4菌丝生长的EC_(50)值为0.16 mg/mL。【结论】从29种中草药提取物中筛选出了抑菌效果较好的大黄提取物,并进一步明确其对香蕉枯萎病菌Foc TR4的主要有效抑菌成分在乙酸乙酯萃取组分中,可为研发防治香蕉枯萎病的植物源新农药提供参考。 展开更多
关键词 中草药植物 提取物 分离组分 香蕉枯萎病 抑菌活性
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中药挥发油透皮促渗苷类成分效果与经皮水分散失量的相关性研究
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作者 黄森兰 祝茜茜 +4 位作者 陆姗姗 宋芝超 董洁 王裔惟 陈军 《南京中医药大学学报》 CAS CSCD 北大核心 2024年第5期503-509,共7页
目的研究中药挥发油透皮促渗苷类成分效果与对经皮水分散失量(Transepidermal water loss,TEWL)的相关性。方法采用HPLC法测定3种苷类成分(栀子苷、龙胆苦苷、芍药苷)的含量及油水分配系数,采用改良Franz扩散池法以离体SD大鼠腹部皮肤... 目的研究中药挥发油透皮促渗苷类成分效果与对经皮水分散失量(Transepidermal water loss,TEWL)的相关性。方法采用HPLC法测定3种苷类成分(栀子苷、龙胆苦苷、芍药苷)的含量及油水分配系数,采用改良Franz扩散池法以离体SD大鼠腹部皮肤为透皮吸收屏障进行体外透皮实验,考察高良姜、干姜、薄荷、胡椒和吴茱萸5种中药挥发油对3种苷类成分的体外透皮促渗效果,采用经皮水分散失量评价5种中药挥发油对大鼠皮肤屏障功能的影响,通过相关性分析考察中药挥发油透皮促渗苷类成分效果与其对皮肤屏障功能影响之间的相关性。结果高良姜油、干姜油、薄荷油、胡椒油能促进3种苷类成分的透皮吸收,也能显著降低大鼠的皮肤屏障功能,相关性分析结果表明中药挥发油对苷类成分的透皮促渗效果与其对皮肤经皮水分散失量的影响显著相关。结论TEWL为中药挥发油透皮促渗剂的快速筛选提供了一种简便快捷的在体评价方法。 展开更多
关键词 中药挥发油 透皮促渗剂 经皮水分散失量 皮肤屏障功能 相关性分析
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《中华人民共和国药典》2020年版收录的中药材与中药制剂的系统分析
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作者 罗皓文 夏秋冬 +4 位作者 刘圆 徐梦 杨扬 张久亮 胡学博 《广州中医药大学学报》 CAS 2024年第5期1348-1353,共6页
对2020年版《中华人民共和国药典》(以下简称《中国药典》)收录的药材和饮片数量、药材与饮片基原物种数与入药部位、成方制剂和单方制剂的数量及组成进行统计和分析,结果载入网站(http://itcm.hzau.edu.cn/yd/zgyd.htm)供参考查询。分... 对2020年版《中华人民共和国药典》(以下简称《中国药典》)收录的药材和饮片数量、药材与饮片基原物种数与入药部位、成方制剂和单方制剂的数量及组成进行统计和分析,结果载入网站(http://itcm.hzau.edu.cn/yd/zgyd.htm)供参考查询。分析显示:(1)《中国药典》(一部)共收录616种药材与饮片以及47种植物油脂与提取物。616种药材和饮片按其来源可分为植物类、动物类、矿物质类、微生物类、人工合成或配置原料类、人源制品、兼具动物与植物来源类等。47种植物油脂与提取物中,46种为以植物来源制成的药材,剩余1种为动物来源,即水牛角浓缩粉。(2)616种药材和饮片中,有421种(占比73.60%)药材源于单一的基原物种,96种(占比16.78%)药材具有2种基原,40种(占比6.99%)药材具有3种基原,11种(占比1.92%)药材具有4种基原,2种(占比0.35%)药材具有5种基原,2种(占比0.35%)药材具有6种基原。47种植物油脂与提取物中,有34种具有单一基原,基原数为2和3的植物油脂与提取物各有5种。(3)《中国药典》(一部)共收录1605种成方和单方制剂。除未公布组成的云南白药和云南白药胶囊外,其余1603种复方制剂和单方制剂一共涉及14329种药材。2020年版《中国药典》成方和单方制剂使用频次最多的前20种药材为甘草、当归、茯苓、川芎、黄芩、白芍、黄芪、陈皮、地黄、白术、丹参、冰片、桔梗、大黄、熟地黄、木香、红花、麦冬、党参以及白芷。结果提示2020年版《中国药典》亦存在药材饮片与处方药材不完全对应、炮制品收录不完整等问题。通过系统分析《中国药典》收录中药材的总体信息及其与处方间的相互关系,可为进一步研究中药材生产与完善处方药材的记录提供参考。 展开更多
关键词 《中华人民共和国药典》 药材与饮片 植物油脂和提取物 基原 成方制剂 单方制剂
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不同种玉米淀粉在杜仲精油中的应用研究
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作者 郑梓威 陈媛媛 +4 位作者 王馨 吴孟仙 王林峰 杨生玉 李星科 《中国粮油学报》 CAS CSCD 北大核心 2024年第6期86-92,共7页
为创新杜仲精油的给药途径,本实验以生物法制备的玉米淀粉为基础,通过酶法制备多孔淀粉和醇法制备V型结晶淀粉,再分别与杜仲精油复合制备杜仲粉末精油,对比研究了不同种玉米淀粉在杜仲精油中的应用情况。结果显示,多孔玉米淀粉与杜仲精... 为创新杜仲精油的给药途径,本实验以生物法制备的玉米淀粉为基础,通过酶法制备多孔淀粉和醇法制备V型结晶淀粉,再分别与杜仲精油复合制备杜仲粉末精油,对比研究了不同种玉米淀粉在杜仲精油中的应用情况。结果显示,多孔玉米淀粉与杜仲精油的复合指数为44%,明显高于其他2种玉米淀粉;结晶性质表明所有的粉末精油都在20.5°的2θ处出现新的吸收峰,说明了复合形成了新的V型结构,其中多孔玉米淀粉粉末精油的强度较其他2种粉末精油更强;热力学性质中的焓值增加也说明了复合物形成了新的化学结构,其中多孔玉米淀粉粉末精油的焓值是最高的;红外扫描中出现新的特征峰进一步证实了玉米淀粉粉末精油产生了新的化学键,其中多孔玉米淀粉粉末精油显示出最强的吸收峰。 展开更多
关键词 玉米淀粉 杜仲精油 中药粉末精油 应用研究
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中药材种植对乡村振兴的影响
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作者 陈姝羽 翟金龙 +4 位作者 刘司琦 房伊文 刘尚 邓玉珍 傅书勇 《科技和产业》 2024年第14期100-105,共6页
为了探讨我国中药材种植与乡村振兴的作用关系,基于2012—2021年30个省份(因数据缺失,未包括西藏地区和港澳台地区)的面板数据,利用广义GMM模型和面板门限模型对中药材种植面积与乡村振兴的关系进行实证研究,并对乡村振兴情况进行空间... 为了探讨我国中药材种植与乡村振兴的作用关系,基于2012—2021年30个省份(因数据缺失,未包括西藏地区和港澳台地区)的面板数据,利用广义GMM模型和面板门限模型对中药材种植面积与乡村振兴的关系进行实证研究,并对乡村振兴情况进行空间相关性分析。结果表明,无论采用何种方法,中药种植面积的系数估计值大多数为正,且在1%的水平下显著;在乡村振兴程度介于-1.868和-1.457时,系数显著为正;全局Moran’s I均通过1%的显著性检验。由此得出结论,中药材种植可以促进我国乡村振兴进程;中药材种植只有在适当的经济发展水平下才能发挥其促进作用;根据不同地区的实际情况制定相应的中药材种植策略和政策,助推乡村振兴。 展开更多
关键词 中药材种植 乡村振兴 门限效应 空间效应
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中药精油药理作用的文献研究
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作者 张金君 钟愧 +1 位作者 韩世范 杨俊 《农产品加工》 2024年第18期130-133,137,共5页
中药精油,又称中药挥发油,是从中草药中萃取的、具有药用价值的芳香型挥发性物质。4700余年前,神农尝百草传说第一次记载了中草药功效,包括了中药精油的药理作用。《中国药典》记录了中药精油具有抗菌、抗炎、抗肿瘤、镇静等功效,因此,... 中药精油,又称中药挥发油,是从中草药中萃取的、具有药用价值的芳香型挥发性物质。4700余年前,神农尝百草传说第一次记载了中草药功效,包括了中药精油的药理作用。《中国药典》记录了中药精油具有抗菌、抗炎、抗肿瘤、镇静等功效,因此,中药精油被广泛应用到药品、食品、化妆品等领域。通过文献综述,研究了中药精油的药理作用,为其开发应用提供参考。 展开更多
关键词 中药精油 药理作用 药品 食品 化妆品
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香茅精油及其复配精油微胶囊对红香酥梨常温保鲜效果
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作者 曹嘉玥 李慧敏 +3 位作者 李玲 尤玲玲 丁润锁 闫师杰 《食品研究与开发》 CAS 2024年第7期88-93,共6页
以红香酥梨为研究对象,β-环糊精(β-cyclodextrin)为壁材,香茅、香茅-月桂中草药精油为芯材,用喷雾干燥法将精油微胶囊化,作为保鲜剂应用于红香酥梨的常温保鲜,探究两种保鲜剂对红香酥梨生理生化指标的影响。结果表明,两种中草药精油... 以红香酥梨为研究对象,β-环糊精(β-cyclodextrin)为壁材,香茅、香茅-月桂中草药精油为芯材,用喷雾干燥法将精油微胶囊化,作为保鲜剂应用于红香酥梨的常温保鲜,探究两种保鲜剂对红香酥梨生理生化指标的影响。结果表明,两种中草药精油微胶囊处理可以延缓红香酥梨采后的硬度、可溶性固形物含量的下降;减缓红香酥梨贮藏过程中色差、失重率、菌落总数的上升,推迟乙烯高峰的出现,保持较高的好果率,具有较好的保鲜效果。因此,香茅、香茅-月桂中草药精油微胶囊可以作为一种天然保鲜剂应用于红香酥梨的保鲜。 展开更多
关键词 红香酥梨 中草药精油 Β-环糊精 微胶囊 保鲜效果
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海藻酸钠复合水凝胶的制备及在中药挥发油缓释领域的应用进展
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作者 俞树琴 王芸 +5 位作者 周强 陈晖 刘雪枫 刘雄 施小宁 高建德 《高分子材料科学与工程》 EI CAS CSCD 北大核心 2024年第4期175-181,共7页
海藻酸钠由于来源广泛、价格低廉,分子中含有大量的羧基、羟基,在较为温和的环境中,能够迅速地构成三维网状结构的水凝胶而受到了人们的广泛关注,但单一的海藻酸钠水凝胶力学性能和力学强度较差。当与其他物质形成复合水凝胶后则因其优... 海藻酸钠由于来源广泛、价格低廉,分子中含有大量的羧基、羟基,在较为温和的环境中,能够迅速地构成三维网状结构的水凝胶而受到了人们的广泛关注,但单一的海藻酸钠水凝胶力学性能和力学强度较差。当与其他物质形成复合水凝胶后则因其优异的生物相容性、生物降解性和pH敏感性被广泛应用于敏感药物的缓控释领域。文中主要介绍了海藻酸钠复合水凝胶的相应制备方法和性能,以及在中药挥发油缓释领域的应用进展,同时指出了海藻酸钠复合水凝胶在中药挥发油缓释领域存在的问题及未来主要的研究方向。 展开更多
关键词 海藻酸钠复合水凝胶 中药挥发油 缓释
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基于两类地理标志分析的溯源饮片原料药材种植基地建设区域选择探讨
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作者 高俊斌 李雨晴 谈景福 《上海医药》 2024年第1期23-28,共6页
溯源饮片的实施基础是原料药材的来源稳定、质量可控,而选择适宜区域建设药材基地、开展规范化生产是达到上述要求的有效手段。国家地理标志和农产品地理标志均用于标识某产品的地域特征,这与优质药材基地建设需关注区域选择有很高的契... 溯源饮片的实施基础是原料药材的来源稳定、质量可控,而选择适宜区域建设药材基地、开展规范化生产是达到上述要求的有效手段。国家地理标志和农产品地理标志均用于标识某产品的地域特征,这与优质药材基地建设需关注区域选择有很高的契合度。本文汇总已在上海市相关医疗机构流通使用的23个溯源饮片品种的两种地理标志登记情况,结合溯源饮片对药材产地的特殊要求,进行区域对比分析,确定符合溯源要求的地理标志产品区域范围,为相关企业在开展溯源饮片原料药材种植基地建设时的区域选择提供参考。 展开更多
关键词 溯源饮片 国家地理标志 农产品地理标志 中药材种植基地 区域选择
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抗生素替代物在畜禽生产中的应用及其作用机制研究进展
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作者 刘宇 王重庆 +2 位作者 梁静泊 潘兴亮 刘钧 《中国农学通报》 2024年第26期126-132,共7页
随着抗生素在饲料中长期添加带来的诸多问题,出现如药物残留、细菌耐药性等问题,对畜禽产品质量和人类健康造成严重威胁,同时也破坏了生态环境。2020年农业农村部194号公告正式实施,饲用促生长抗生素添加剂被全面禁止,标志着畜禽行业“... 随着抗生素在饲料中长期添加带来的诸多问题,出现如药物残留、细菌耐药性等问题,对畜禽产品质量和人类健康造成严重威胁,同时也破坏了生态环境。2020年农业农村部194号公告正式实施,饲用促生长抗生素添加剂被全面禁止,标志着畜禽行业“禁抗”时代的到来,无抗养殖成为畜禽养殖业发展的大趋势。抗生素替代物能够提高动物的生长性能,改善动物肠道健康及调节宿主免疫系统,并具有安全、高效、低残留、低污染的优势,在饲料添加应用上具有很大前景。因此,文章就抗生素替代物微生态制剂(益生菌、益生元、合生元)、植物提取物、中草药、有机酸、抗菌肽等较为广泛的绿色添加剂的应用及其作用机制研究进展进行综述,以期为畜禽健康养殖提供参考,推动中国畜禽养殖业绿色健康发展。 展开更多
关键词 畜禽 抗生素替代物 绿色养殖 健康养殖 作用机制 抗生素替代品 微生态制剂 植物提取物 中草药 有机酸 抗菌肽 畜禽健康
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中药复方精油联合小儿推拿治疗脾虚气滞型儿童FD疗效观察
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作者 张蕴 黄柳清 高诗晴 《智慧健康》 2024年第7期150-153,共4页
目的 探讨中药复方精油联合小儿推拿治疗脾虚气滞型儿童功能性消化不良(FD)的临床疗效。方法 选取2021年6月—2022年6月在福建省福州儿童医院中医科就诊治疗的58例脾虚气滞型FD患儿为研究对象,采用随机数字表法分成观察组(n=30)和对照组... 目的 探讨中药复方精油联合小儿推拿治疗脾虚气滞型儿童功能性消化不良(FD)的临床疗效。方法 选取2021年6月—2022年6月在福建省福州儿童医院中医科就诊治疗的58例脾虚气滞型FD患儿为研究对象,采用随机数字表法分成观察组(n=30)和对照组(n=28),观察组予以中药复方精油配合小儿推拿治疗,对照组仅给予小儿推拿治疗,均为每天推拿1次,连续治疗5d间隔2d为一个疗程,共2个疗程。比较两组的临床疗效、总体症状积分和中医症候评分。结果 观察组临床有效率高于对照组,组间可见统计学差异(P<0.05)。治疗前,两组间的中医症状总体积分与各主要症候评分比较,均未见显著差异性(P>0.05);治疗后,两组各主要中医症候评分均可见显著下降,症状总体积分均较之前显著改善(P<0.01)。观察组治疗后显著优于对照组,组间可见统计学差异(P<0.05或P<0.01)。结论 采用中药复方精油配合小儿推拿治疗脾虚气滞型儿童FD,能显著改善患儿胃脘痞闷或胀痛、纳呆、嗳气、疲乏、便溏等不适症状,且治疗效果显著优于单用小儿推拿手法治疗。 展开更多
关键词 中药复方精油 小儿推拿 儿童 功能性消化不良 疗效
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Constituents of the anti-asthma herbal formula ASHMI^(TM) synergistically inhibit IL-4 and IL-5 secretion by murine Th2 memory cells,and eotaxin by human lung fibroblasts in vitro 被引量:15
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作者 Bolleddula Jayaprakasam Nan Yang +4 位作者 Ming-Chun Wen Rong Wang Joseph Goldfarb Hugh Sampson Xiu-Min Li 《Journal of Integrative Medicine》 SCIE CAS CSCD 2013年第3期195-205,共11页
OBJECTIVE: Anti-asthma herbal medicine intervention (ASHMITM), a combination of three tradi- tional Chinese medicinal herbs developed in our laboratory, has demonstrated efficacy in both mouse models of allergic as... OBJECTIVE: Anti-asthma herbal medicine intervention (ASHMITM), a combination of three tradi- tional Chinese medicinal herbs developed in our laboratory, has demonstrated efficacy in both mouse models of allergic asthma, and a double-blind placebo-controlled clinical trial in patients with asthma. This study was designed to determine if the anti-inflammatory effects of individual herbal constituents of ASHMITM exhibited synergy. METHODS: Effects of ASHMI and its components aqueous extracts of Lingzhi (Ganoderma lucidum), Kushen (Sophora flavescens) and Gancao (Glycyrrhiza uralensis), on Th2 cytokine secretion by murine memory Th2 cells (D10.G4.1) and eotaxin-1 secretion by human lung fibroblast (HLF-1) cells were determined by measuring levels in culture supernatants by enzyme- linked immunosorbent assay. Potential synergistic effects were determined by computing interaction indices from concentration-effect curve parameters. RESULTS: Individual Lingzhi, Kushen and Gancao extracts and ASHMI (the combination of individual extracts) inhibited production of interleukin (IL)-4 and IL-5 by murine memory Th2 cells and eotaxin-1 production by HLF-1 cells. The mean 25%-inhibitory-concentration (IC2s) values (mg/mL) forASHMI, Lingzhi, Kushen and Gancao for IL-4 production were 30.9, 79.4, 123, and 64.6, respectively; for IL-5 production were 30.2, 263, 123.2 and 100, respectively; for eotaxin-1 were 13.2, 16.2, 30.2, and 25.1, respectively. The IC50values (mg/mL) for ASHMI, Lingzhi, Kushen and Gancao for IL-4 production were 158.5, 239.9, 446.7, and 281.8, respectively; for eotaxin-1 were 38.1, 33.1, 100, and 158.5, respectively. The interaction indices of ASHMI constituents at IC25 were 0.35 for IL-4, 0.21 for IL-5 and 0.59 for eotaxin-l. The interaction indices at IC^0 values were 0.50 for IL-4 and 0.62 for eotaxin-1 inhibition. Inhibition of IL-5 did not reach IC^0 values. All interaction indices were below 1 which indicated synergy. CONCLUSION: By comparing the interaction index values, we find that constituents in ASHMITM synergistically inhibited eotaxin-1 production as well as Th2 cytokine production. 展开更多
关键词 medicine chinese traditional medicine herbal plant extracts anti-asthma herbal medicine intervention (ASHMI) anti-asthmatic agents chemokine CCL11 INTERLEUKIN-4 interleukin -5 in vitro
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Effect of Chinese Herbal Medicine for Calming Gan(肝) and Suppressing Hyperactive Yang on Arterial Elasticity Function and Circadian Rhythm of Blood Pressure in Patients with Essential Hypertension 被引量:8
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作者 钟广伟 陈民敬 +5 位作者 罗艳红 相玲丽 谢启应 李云辉 张臣 高峰 《Chinese Journal of Integrative Medicine》 SCIE CAS 2011年第6期414-420,共7页
Objective:To observe the effect of Chinese herbal medicine for calming Gan(肝) and suppressing hyperactive yang(平肝潜阳,CGSHY) on arterial elasticity function and the circadian rhythm of blood pressure in patien... Objective:To observe the effect of Chinese herbal medicine for calming Gan(肝) and suppressing hyperactive yang(平肝潜阳,CGSHY) on arterial elasticity function and the circadian rhythm of blood pressure in patients with essential hypertension(EH).Methods:Adopting a parallel,randomized design,sixty-four patients with EH of stagesⅠandⅡwere randomly divided into two groups according to a random number table,with 32 in each group.The patients in the treatment group were treated with CGSHY and those in the control group were treated with Enalapril.All patients were given 24-h ambulatory blood pressure monitoring(ABPM) before and after a 12-week treatment.Trough/peak(T/P) ratios of systolic and diastolic blood pressure(SBP DBP) of each group were calculated.The circadian rhythm of their blood pressure was observed at the same time. The changes in elasticity of the carotid artery in the patients,including stiffness parameter(β),pressure-strain elastic modulus(Ep),arterial compliance(AC),augmentation index(Al),and pulse wave velocity(PVWβ) were determined by the echo-tracking technique before and after a 12-week treatment.In the meantime,their levels of nitric oxide(NO) and endothelin-1(ET-1) were measured respectively.Results:After treatment,all parameters in the 24-h ABPM and the elasticity of the carotid artery(β,Ep,AC and PVWβ) were markedly improved,the level of NO was increased,and ET-1 was decreased in both groups as compared with values before treatment (P0.05 or P0.01).Further,the improvements in the ratio of T/P of SBP DBP and in the level of NO and ET-1 in the treatment group were more significant than those in the control group(P0.05).There were no significant differences in all parameters in the ABPM monitoring and the elasticity of the carotid artery,the recovery of blood pressure circadian rhythm,and the therapeutic effect of antihypertension in EH patients between the two groups (P0.05).Conclusions:Chinese herbal medicine for CGSHY may lower the blood pressure smoothly and recover the circadian rhythm of blood pressure in EH patients.They may also improve the carotid elasticity of EH patients similar to that of Enalapril.The mechanism of action of Chinese herbs on EH might be related to the regulation of vascular endothelium function. 展开更多
关键词 essential hypertension circadian rhythm of blood pressure chinese herbal medicine for calmingGan and suppressing hyperactive yang artery elasticity function
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