Objectives:To evaluate the benefits of traditional Chinese herbal medicine(TCHM)plus triple therapy(TT)in the management of Helicobacter pylori(H.pylori)-induced chronic atrophic gastritis(CAG).Methods:A comprehensive...Objectives:To evaluate the benefits of traditional Chinese herbal medicine(TCHM)plus triple therapy(TT)in the management of Helicobacter pylori(H.pylori)-induced chronic atrophic gastritis(CAG).Methods:A comprehensive access and electronic database search were carried out from inception to June 2020.Prospective randomized trials(TCHM plus TT vs.TT)were selected to assess the eradication rate of H.pylori(ER of H.pylori),clinical symptom relief rate(SRR),treatment-related adverse reactions(TRAR)and 95%confidence intervals(CI)in the meta-analysis and cumulative meta-analysis(CMA).Meta-regression analysis was used to analyze heterogeneity between studies and publication bias.Results:33 studies contained 3,226 participants were included.Compared with the TT group,TCHM plus TT group showed a significantly higher ER of H.pylori(OR=4.14,95%CI:3.21-5.35;P=0.000)and SRR(OR=4.50,95%CI:3.59-5.64).Meanwhile,the TRAR of TCHM plus TT remedy was significantly lower than TT monopoly(RR=0.43,95%CI:0.29-0.64;P=0.000).The results of the CMA,sorted by publication year,duration of treatment,and sample size,confirmed that combined treatment remedy was superior to TT monopoly in respect of ER of H.pylori and SRR.Conclusions:The present study obtained reliable and convincing evidence suggesting that TCHM plus TT remedy was efficacious and safe in treating H.pylori-induced CAG.展开更多
目的:分析中医三联疗法联合融入加速康复外科(enhanced recovery after surgery,ERAS)理念的临床护理路径对胃癌围术期患者的影响。方法:选取54例胃癌手术患者为研究对象,按照随机数字表法分为对照组和观察组各27例,对照组采用常规护理...目的:分析中医三联疗法联合融入加速康复外科(enhanced recovery after surgery,ERAS)理念的临床护理路径对胃癌围术期患者的影响。方法:选取54例胃癌手术患者为研究对象,按照随机数字表法分为对照组和观察组各27例,对照组采用常规护理干预,观察组在对照组基础上加用中医三联疗法联合融入ERAS理念的临床护理路径,比较两组干预效果。结果:观察组肛门排气时间、胃管拔除时间、首次下床活动时间均短于对照组(P<0.05);手术前1天、首次下床活动时、出院时观察组心理痛苦温度计(dis-tress thermometer,DT)评分均低于对照组(P<0.05);观察组并发症发生率[7.4%(2/27)]低于对照组[29.6%(8/27)](P<0.05),术前1天、术后15天视觉模拟评分量表评分均低于对照组(P<0.05),患者满意度高于对照组(P<0.05)。结论:在胃癌患者围术期应用中医三联疗法联合融入ERAS理念的临床护理路径,能够促进胃癌术后患者胃肠功能恢复,改善其心理状况,降低疼痛程度和并发症发生率,提高患者满意度。展开更多
基金The National Key Research and Development Program(No.2018YFC1704500).
文摘Objectives:To evaluate the benefits of traditional Chinese herbal medicine(TCHM)plus triple therapy(TT)in the management of Helicobacter pylori(H.pylori)-induced chronic atrophic gastritis(CAG).Methods:A comprehensive access and electronic database search were carried out from inception to June 2020.Prospective randomized trials(TCHM plus TT vs.TT)were selected to assess the eradication rate of H.pylori(ER of H.pylori),clinical symptom relief rate(SRR),treatment-related adverse reactions(TRAR)and 95%confidence intervals(CI)in the meta-analysis and cumulative meta-analysis(CMA).Meta-regression analysis was used to analyze heterogeneity between studies and publication bias.Results:33 studies contained 3,226 participants were included.Compared with the TT group,TCHM plus TT group showed a significantly higher ER of H.pylori(OR=4.14,95%CI:3.21-5.35;P=0.000)and SRR(OR=4.50,95%CI:3.59-5.64).Meanwhile,the TRAR of TCHM plus TT remedy was significantly lower than TT monopoly(RR=0.43,95%CI:0.29-0.64;P=0.000).The results of the CMA,sorted by publication year,duration of treatment,and sample size,confirmed that combined treatment remedy was superior to TT monopoly in respect of ER of H.pylori and SRR.Conclusions:The present study obtained reliable and convincing evidence suggesting that TCHM plus TT remedy was efficacious and safe in treating H.pylori-induced CAG.
文摘目的:分析中医三联疗法联合融入加速康复外科(enhanced recovery after surgery,ERAS)理念的临床护理路径对胃癌围术期患者的影响。方法:选取54例胃癌手术患者为研究对象,按照随机数字表法分为对照组和观察组各27例,对照组采用常规护理干预,观察组在对照组基础上加用中医三联疗法联合融入ERAS理念的临床护理路径,比较两组干预效果。结果:观察组肛门排气时间、胃管拔除时间、首次下床活动时间均短于对照组(P<0.05);手术前1天、首次下床活动时、出院时观察组心理痛苦温度计(dis-tress thermometer,DT)评分均低于对照组(P<0.05);观察组并发症发生率[7.4%(2/27)]低于对照组[29.6%(8/27)](P<0.05),术前1天、术后15天视觉模拟评分量表评分均低于对照组(P<0.05),患者满意度高于对照组(P<0.05)。结论:在胃癌患者围术期应用中医三联疗法联合融入ERAS理念的临床护理路径,能够促进胃癌术后患者胃肠功能恢复,改善其心理状况,降低疼痛程度和并发症发生率,提高患者满意度。
