In the hands of chef Bai Changji, tofu (soybean curd) alone can be turned out to be a banquet of more than 200 kinds of cuisine. Even the bean dregs after making tofu will be cooked into dishes.
This study investigates the motivations of Chinese domestic tourists visiting seismic memorial sites after the great Wenchuan earthquake of 2008, and examines their interpretation of experiences and benefits of the vi...This study investigates the motivations of Chinese domestic tourists visiting seismic memorial sites after the great Wenchuan earthquake of 2008, and examines their interpretation of experiences and benefits of the visits. Recent research on dark tourism has raised the possibility that people are attracted to death and memorial sites in ways different from other tourist attractions. The study used an empirical research design employing questionnaires to collect data from 255 Chinese domestic visitors at seismic memorial sites in west Sichuan. Analysis revealed that the obligation of commemoration mixed with curiosity represents a different set of travel motivation in dark tourism settings than in other kinds of tourism. In addition, the empirical evidence also suggests an interrelated pattern between motivations, experiences and benefits. This study implies that Chinese domestic tourists were attracted in ways different from other tourist attractions both because they tended to fulfill their obligation of commemoration and were interested in destruction; and visitor experiences played an important mediating role between travel motivations and benefits gained.展开更多
Objective:To determine the effects of 5-hydroxymethyl furfural(5-HMF),an extract of Rehmannia glutinosa Libosch,on several down-regulated signaling molecules involved in learning and memory in hippocampal neurons.M...Objective:To determine the effects of 5-hydroxymethyl furfural(5-HMF),an extract of Rehmannia glutinosa Libosch,on several down-regulated signaling molecules involved in learning and memory in hippocampal neurons.Methods:After cultured for 7 days,primary hippocampal neurons were divided into 5 groups:normal,corticosterone model,RU38486,5-HMF,and donepezil group.Neuron survival rates were calculated 24 h later using SYT013-P1 double-fluorescence staining and an 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay.β-galactosidase activity was also assayed.Protein expressed by the glucocorticoid receptor(GCR),brainderived neurotrophic factor(BDNF),and N-methyl-D-aspartate receptor 2B(NR2B),as well as phosphorylationcyclic adenosine monophosphate(cAMP)response element binding protein(p-CREB),phosphorylation-extracellular signal-regulated kinase(p-ERK),and phosphorylation-synapsin(p-synapsin)were quantified with Western blot.Results:Hippocampal neuron survival rates and the above-mentioned proteins were dramatically decreased(P〈0.05),β-galactosidase activity was significantly increased in the model group,but the effect was reversed by5-HMF,RU38486,and to a lesser extent by donepezil(P〈0.05).Conclusion:5-HMF extracts from the Chinese herb Rehmannia glutinosa Libosch could protect hippocampal neurons from glucocorticoid injury and from down-regulated signaling molecules in the GCR-BDNF-NR2B-p-ERK-p-CREB-p-synapsin signal transduction pathway.展开更多
文摘In the hands of chef Bai Changji, tofu (soybean curd) alone can be turned out to be a banquet of more than 200 kinds of cuisine. Even the bean dregs after making tofu will be cooked into dishes.
基金supported by the China Scholarship Council(Liujinfa[2011]No.5024)the Key Teachers Development Fellowship Program of CDUT(KYGG201313)the Center for Folk Culture Studies(MJ13-09)
文摘This study investigates the motivations of Chinese domestic tourists visiting seismic memorial sites after the great Wenchuan earthquake of 2008, and examines their interpretation of experiences and benefits of the visits. Recent research on dark tourism has raised the possibility that people are attracted to death and memorial sites in ways different from other tourist attractions. The study used an empirical research design employing questionnaires to collect data from 255 Chinese domestic visitors at seismic memorial sites in west Sichuan. Analysis revealed that the obligation of commemoration mixed with curiosity represents a different set of travel motivation in dark tourism settings than in other kinds of tourism. In addition, the empirical evidence also suggests an interrelated pattern between motivations, experiences and benefits. This study implies that Chinese domestic tourists were attracted in ways different from other tourist attractions both because they tended to fulfill their obligation of commemoration and were interested in destruction; and visitor experiences played an important mediating role between travel motivations and benefits gained.
基金Support by the National Natural Science Foundation of China(No.30873317),Leading Academic Discipline Project of Shanghai Municipal Education Commission(No.J50301),Shanghai Health Bureau of Scientific Research Projects(No.20124Y025)
文摘Objective:To determine the effects of 5-hydroxymethyl furfural(5-HMF),an extract of Rehmannia glutinosa Libosch,on several down-regulated signaling molecules involved in learning and memory in hippocampal neurons.Methods:After cultured for 7 days,primary hippocampal neurons were divided into 5 groups:normal,corticosterone model,RU38486,5-HMF,and donepezil group.Neuron survival rates were calculated 24 h later using SYT013-P1 double-fluorescence staining and an 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay.β-galactosidase activity was also assayed.Protein expressed by the glucocorticoid receptor(GCR),brainderived neurotrophic factor(BDNF),and N-methyl-D-aspartate receptor 2B(NR2B),as well as phosphorylationcyclic adenosine monophosphate(cAMP)response element binding protein(p-CREB),phosphorylation-extracellular signal-regulated kinase(p-ERK),and phosphorylation-synapsin(p-synapsin)were quantified with Western blot.Results:Hippocampal neuron survival rates and the above-mentioned proteins were dramatically decreased(P〈0.05),β-galactosidase activity was significantly increased in the model group,but the effect was reversed by5-HMF,RU38486,and to a lesser extent by donepezil(P〈0.05).Conclusion:5-HMF extracts from the Chinese herb Rehmannia glutinosa Libosch could protect hippocampal neurons from glucocorticoid injury and from down-regulated signaling molecules in the GCR-BDNF-NR2B-p-ERK-p-CREB-p-synapsin signal transduction pathway.