Absorbance and fluorescence methods were used to study the interaction of - and A-tris (phenanthroline) nickel ( Ⅱ) complex with calf thymus DNA. It was con- cluded that -Ni(phen). preferentially bound to DNA. Espec...Absorbance and fluorescence methods were used to study the interaction of - and A-tris (phenanthroline) nickel ( Ⅱ) complex with calf thymus DNA. It was con- cluded that -Ni(phen). preferentially bound to DNA. Especially the fluorescence Scatchard plots were discussed for the binding of EthBr to calf thymus DNA in the presence of varying concentrations of the metal complex. Theses studies indicated that both the isomers bound to DNA by two acting types , namely , intercalative and electrostatic bound modes.展开更多
The interactions of Morin and its Cu(Ⅱ)-, Zn(Ⅱ)-complexes with calf thymus DNA have been studied by using fluorimetric and electrochemical methods. Cu(Ⅱ)-, Zn(Ⅱ)-complexes have different spectra and electrochemica...The interactions of Morin and its Cu(Ⅱ)-, Zn(Ⅱ)-complexes with calf thymus DNA have been studied by using fluorimetric and electrochemical methods. Cu(Ⅱ)-, Zn(Ⅱ)-complexes have different spectra and electrochemical characteristics from that of Morin in the presence of DNA. The results suggest that Morin and its complexes can both bind to DNA, but the binding mode is different. The complexes bind to DNA mainly like EB by intercalation, while Morin binds in a non-intercalating mode.展开更多
文摘Absorbance and fluorescence methods were used to study the interaction of - and A-tris (phenanthroline) nickel ( Ⅱ) complex with calf thymus DNA. It was con- cluded that -Ni(phen). preferentially bound to DNA. Especially the fluorescence Scatchard plots were discussed for the binding of EthBr to calf thymus DNA in the presence of varying concentrations of the metal complex. Theses studies indicated that both the isomers bound to DNA by two acting types , namely , intercalative and electrostatic bound modes.
文摘The interactions of Morin and its Cu(Ⅱ)-, Zn(Ⅱ)-complexes with calf thymus DNA have been studied by using fluorimetric and electrochemical methods. Cu(Ⅱ)-, Zn(Ⅱ)-complexes have different spectra and electrochemical characteristics from that of Morin in the presence of DNA. The results suggest that Morin and its complexes can both bind to DNA, but the binding mode is different. The complexes bind to DNA mainly like EB by intercalation, while Morin binds in a non-intercalating mode.
