To analyze the effect of two types of IUDs, TCu380A and GyneFix on the positive rate of Chlamydia Trahmatis (CT). Methods The TCu380A and GyneFix IUDs were compared in a randomized was for the one year and two year...To analyze the effect of two types of IUDs, TCu380A and GyneFix on the positive rate of Chlamydia Trahmatis (CT). Methods The TCu380A and GyneFix IUDs were compared in a randomized was for the one year and two year positive rate of Chlamydia Trahmatis (CT) and with the control respectively. Results The one year positive rate of CT antigens was 5.63% of TCu380A and two year was 4.92%; the one year positive rate of CT antigens was 4.62% and two year was 5.08% of GyneFix. There was no significant difference in the positive rate of CT antigen between the TCu380A IUD, and GyneFix IUDs groups, while there were significant differences between the TCu380A IUD, GyneFix IUD and the controls (15.18%) respectively. Conclusion Both IUDs provide highly effective protection against CT infection.展开更多
Object: To investigate the relationship between chlamydiatrachomatis (CT) and urogenital infection. Method Positive rate of CT in patients with inflammationof urogenital tract was significantly higher than those witho...Object: To investigate the relationship between chlamydiatrachomatis (CT) and urogenital infection. Method Positive rate of CT in patients with inflammationof urogenital tract was significantly higher than those withoutinflammation(P<0.05). Result: There was statistical difference in the males nomatter they were patients with inflammation of urogenitaltract or not (P>H0.05), while there was no statistical differencein females (P>0.05). The incidence of the infection was highamong those aging from 21-50 years old. Conclusion: The clinical manifestations of CT infectionwere obscure, so we should examine CT in patients who haveno symptoms, especially in females and those of high-riskpopulation.展开更多
Objectives: To find out the level and functions of Chlamydia trachomatis heat shock protein (C-hsp60) antibody, anti-spermantibody(ASAb), interleukin 1(IL-1), interleukin 6 (IL-6),interleukin 8 (IL-8), Tumor necrosis ...Objectives: To find out the level and functions of Chlamydia trachomatis heat shock protein (C-hsp60) antibody, anti-spermantibody(ASAb), interleukin 1(IL-1), interleukin 6 (IL-6),interleukin 8 (IL-8), Tumor necrosis factor alpha (TNF-α)and γ-interferon (IFN-γ) in patients with CT-related infertility. Methods: CT-DNA of cervical secretions was detectedthrough polymerase chain reaction (PCR) and migrationinhibiting factor (MIF) was employed to measure IgG titre ofCT MOMP antibody. Western blot was used to determinepresence of C-hsp60 antibody and enzyme-linkedimmunoadsorbent assay (ELISA) measured ASAb of IgG typein blood serum and determine the content of IL-1, IL-6. IL-8.TNF-α. IFN-γ in uterine tube fluid. Results: 68 patients had positive CT-DNA, among which 57(83.8%) had C-hsp60 antibody. Among the 172 patients withnegative CT-DNA, 64 patients (37.2%) also had C-hsp60Antibody. There was a significant difference (P<0.01) betweeninfertile patients and control group patients in the presence ofAAb. Infertile patients with positive CT-DNA had higher levels of IL-1、IL-6. IL-8. TNF-α. IFN-γ in uterine tube fluidcompared to control group patients (P<0.01). Conclusion: Firstly, those patients with negative CT testingfrom cervical secretions cannot be ruled out for CT infectionin deep parts of the body (such as oviduct, pelvic kidney).Detection of C-hsp60 Antibody may help to diagnose suchcases of CT. Secondly, CT infection of the oviduct can raiselevels of IL-1、IL-6、 IL-8、 TNF-α. IFN-γ. The pathogenesis ofinfertility caused by CT infection in the reproductive tractmay be related to cytokine production and inflammatoryresponses mediated by C-hsp60 Antibody, IL-1, IL-6, IL-8,TNF-α, and IFN-γ.展开更多
文摘To analyze the effect of two types of IUDs, TCu380A and GyneFix on the positive rate of Chlamydia Trahmatis (CT). Methods The TCu380A and GyneFix IUDs were compared in a randomized was for the one year and two year positive rate of Chlamydia Trahmatis (CT) and with the control respectively. Results The one year positive rate of CT antigens was 5.63% of TCu380A and two year was 4.92%; the one year positive rate of CT antigens was 4.62% and two year was 5.08% of GyneFix. There was no significant difference in the positive rate of CT antigen between the TCu380A IUD, and GyneFix IUDs groups, while there were significant differences between the TCu380A IUD, GyneFix IUD and the controls (15.18%) respectively. Conclusion Both IUDs provide highly effective protection against CT infection.
文摘Object: To investigate the relationship between chlamydiatrachomatis (CT) and urogenital infection. Method Positive rate of CT in patients with inflammationof urogenital tract was significantly higher than those withoutinflammation(P<0.05). Result: There was statistical difference in the males nomatter they were patients with inflammation of urogenitaltract or not (P>H0.05), while there was no statistical differencein females (P>0.05). The incidence of the infection was highamong those aging from 21-50 years old. Conclusion: The clinical manifestations of CT infectionwere obscure, so we should examine CT in patients who haveno symptoms, especially in females and those of high-riskpopulation.
基金The Project was funded by the Department of Education,Jangsu Province(Fund Number: 00KJD310003).
文摘Objectives: To find out the level and functions of Chlamydia trachomatis heat shock protein (C-hsp60) antibody, anti-spermantibody(ASAb), interleukin 1(IL-1), interleukin 6 (IL-6),interleukin 8 (IL-8), Tumor necrosis factor alpha (TNF-α)and γ-interferon (IFN-γ) in patients with CT-related infertility. Methods: CT-DNA of cervical secretions was detectedthrough polymerase chain reaction (PCR) and migrationinhibiting factor (MIF) was employed to measure IgG titre ofCT MOMP antibody. Western blot was used to determinepresence of C-hsp60 antibody and enzyme-linkedimmunoadsorbent assay (ELISA) measured ASAb of IgG typein blood serum and determine the content of IL-1, IL-6. IL-8.TNF-α. IFN-γ in uterine tube fluid. Results: 68 patients had positive CT-DNA, among which 57(83.8%) had C-hsp60 antibody. Among the 172 patients withnegative CT-DNA, 64 patients (37.2%) also had C-hsp60Antibody. There was a significant difference (P<0.01) betweeninfertile patients and control group patients in the presence ofAAb. Infertile patients with positive CT-DNA had higher levels of IL-1、IL-6. IL-8. TNF-α. IFN-γ in uterine tube fluidcompared to control group patients (P<0.01). Conclusion: Firstly, those patients with negative CT testingfrom cervical secretions cannot be ruled out for CT infectionin deep parts of the body (such as oviduct, pelvic kidney).Detection of C-hsp60 Antibody may help to diagnose suchcases of CT. Secondly, CT infection of the oviduct can raiselevels of IL-1、IL-6、 IL-8、 TNF-α. IFN-γ. The pathogenesis ofinfertility caused by CT infection in the reproductive tractmay be related to cytokine production and inflammatoryresponses mediated by C-hsp60 Antibody, IL-1, IL-6, IL-8,TNF-α, and IFN-γ.
