The effective chlorolactonization of alkenoic acids with（diacetoxyiodo）benzene and lithium chloride under mild conditions have been studied.Experiments show that various 4-pentenoic acids react with（diacetoxyiodo）...The effective chlorolactonization of alkenoic acids with（diacetoxyiodo）benzene and lithium chloride under mild conditions have been studied.Experiments show that various 4-pentenoic acids react with（diacetoxyiodo）benzene and lithium chloride fluently in CH_3OH at room temperature,obtaining five-membered chlorolactones in good yields in short times.Other alkenoic acids,such as 3-butenoic acid and trans 3-hexenoic acid give some more complicated results,and 4-pentynoic acid provides a chloroenol lactone with Z configuration in 40%of yield.展开更多
基金Financial support from the Zhejiang Province Natural Science Foundation of China(No.Y4080068)
文摘The effective chlorolactonization of alkenoic acids with（diacetoxyiodo）benzene and lithium chloride under mild conditions have been studied.Experiments show that various 4-pentenoic acids react with（diacetoxyiodo）benzene and lithium chloride fluently in CH_3OH at room temperature,obtaining five-membered chlorolactones in good yields in short times.Other alkenoic acids,such as 3-butenoic acid and trans 3-hexenoic acid give some more complicated results,and 4-pentynoic acid provides a chloroenol lactone with Z configuration in 40%of yield.
