Human peripheral blood exposed with 188ReO4 at various radioactivities for 54h was examined to observe the chromosome and chromatin aberrations at metaphases in the mitosis of lymphocytes. The findings indicate that t...Human peripheral blood exposed with 188ReO4 at various radioactivities for 54h was examined to observe the chromosome and chromatin aberrations at metaphases in the mitosis of lymphocytes. The findings indicate that there is an increasing tendency of the aberration yields of both types with increasing 188ReO4 concentration and a dose dependency could be obtained. The aberration yield was best fitted by a quadratic model. Chromatin aberrations, aberration cells and chromosome fragments were fitted into a linear-regression model.展开更多
The effects of pulsing electromagnetic fields(PEMFs)on cells are very important subjects in the field of bioelectromagnetics.In this experiment,the cytogenetic effects of PEMF on domestic pig lymphocytes were tested i...The effects of pulsing electromagnetic fields(PEMFs)on cells are very important subjects in the field of bioelectromagnetics.In this experiment,the cytogenetic effects of PEMF on domestic pig lymphocytes were tested in vitro.Pig lymphocytes in RPMI 1640 medium were exposed to PEMFs of 100 kHz and 200 kHz for 12,24 and 48 hours.Chromosomal aberrations(aneuploidy,breaks,gaps,et al)were significantly increased in exposed cultures,and of these aberrations,56%chromosomal or chromatid breaks and 42%gaps induced by PEMFs were the points of pig chromosomal fragile sites.The baseline frequency of sister chromatid exchange(SCE)increased after exposing lymphocytes continuously to PEMFs of 100 kHz and 200 kHz for 48 hours.These results suggested that the exposure to PEMFs might induce a type of DNA lesion and chromosomal aberrations.展开更多
Objective To investigate chromosome aberration and micronucleus frequency in peripheral blood lymphocytes in workers engaged in radiation for a long time,to reduce occupational hazard caused by ionizing radiation and ...Objective To investigate chromosome aberration and micronucleus frequency in peripheral blood lymphocytes in workers engaged in radiation for a long time,to reduce occupational hazard caused by ionizing radiation and to further strengthen health surveillance.Methods A total of 366 members of medical staff engaged in radiation work who underwent physical examinations in展开更多
文摘Human peripheral blood exposed with 188ReO4 at various radioactivities for 54h was examined to observe the chromosome and chromatin aberrations at metaphases in the mitosis of lymphocytes. The findings indicate that there is an increasing tendency of the aberration yields of both types with increasing 188ReO4 concentration and a dose dependency could be obtained. The aberration yield was best fitted by a quadratic model. Chromatin aberrations, aberration cells and chromosome fragments were fitted into a linear-regression model.
文摘The effects of pulsing electromagnetic fields(PEMFs)on cells are very important subjects in the field of bioelectromagnetics.In this experiment,the cytogenetic effects of PEMF on domestic pig lymphocytes were tested in vitro.Pig lymphocytes in RPMI 1640 medium were exposed to PEMFs of 100 kHz and 200 kHz for 12,24 and 48 hours.Chromosomal aberrations(aneuploidy,breaks,gaps,et al)were significantly increased in exposed cultures,and of these aberrations,56%chromosomal or chromatid breaks and 42%gaps induced by PEMFs were the points of pig chromosomal fragile sites.The baseline frequency of sister chromatid exchange(SCE)increased after exposing lymphocytes continuously to PEMFs of 100 kHz and 200 kHz for 48 hours.These results suggested that the exposure to PEMFs might induce a type of DNA lesion and chromosomal aberrations.
文摘Objective To investigate chromosome aberration and micronucleus frequency in peripheral blood lymphocytes in workers engaged in radiation for a long time,to reduce occupational hazard caused by ionizing radiation and to further strengthen health surveillance.Methods A total of 366 members of medical staff engaged in radiation work who underwent physical examinations in
