Objective: To investigate the effects of terbutaline combined with methylprednisolone on pulmonary function, blood gas analysis and inflammatory factors in patients with chronic obstructive pulmonary disease (COPD). M...Objective: To investigate the effects of terbutaline combined with methylprednisolone on pulmonary function, blood gas analysis and inflammatory factors in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 100 patients with COPD were randomly divided into control group (n=50) and observation group (n=50) according to the lottery method. Both groups were treated with conventional therapy. On this basis, the control group was given inhalation of terbutaline. The observation group was given terbutaline inhalation and combination therapy with methylprednisolone. The changes of lung function, changes of blood gas analysis and inflammatory factors were measured before and after treatment in both groups. Results: There were no significant differences in lung function between the two groups before treatment. After treatment, the levels of FVC and FEV1 in both groups were significantly higher than those before treatment, and that of the observation group was higher than those of the control group. Before treatment, there was no significant difference between the two groups. After treatment, PaO2 levels in both groups were significantly higher than those before treatment, and that of the observation group was higher than those of the control group. After treatment, PaCO2 levels in both groups were significantly lower than those before treatment, and the observation group was lower than the control group after treatment. There were no significant differences in the levels of inflammatory factors between the two groups before treatment. After treatment, the levels of PCT and TNF-α in both groups were significantly lower than those before treatment, and those of the observation group was lower than those of the control group after treatment. Conclusion: The effect of Terbutaline combined with methylprednisolone treatment of COPD is better, which can significantly improve lung function, stable blood gas analysis, reduce the concentration of inflammatory factors, and be a potential effective treatment programs.展开更多
目的探讨老年慢性支气管炎优质化护理的效果。方法回顾性选取2020年2月—2023年2月泉州市第一医院老年病院分院呼吸与危重症学科收治的100例老年慢性支气管炎患者的临床资料,依据护理方法分为观察组、参照组,各50例,观察组患者接受优质...目的探讨老年慢性支气管炎优质化护理的效果。方法回顾性选取2020年2月—2023年2月泉州市第一医院老年病院分院呼吸与危重症学科收治的100例老年慢性支气管炎患者的临床资料,依据护理方法分为观察组、参照组,各50例,观察组患者接受优质化护理,参照组患者接受常规化护理。统计分析两组血气指标、肺通气功能指标、生命质量、症状评分、护理依从性、护理满意度。结果观察组患者的二氧化碳分压(Partial Pressure of Carbon Dioxide,PaCO_(2))、症状评分低于参照组,血氧饱和度(Oxygen Saturation,SaO_(2))、氧分压(Oxygen Partial Pressure,PaO_(2))、第1秒用力呼气容积(Forced Expiratory Volume in the First Second,FEV1)、用力肺活量(Forced Vital Capacity,FVC)、认知、角色、情绪、躯体、社会均高于参照组,差异有统计学意义(P均<0.05)。观察组护理依从性为96.00%,高于参照组的66.00%,差异有统计学意义(χ^(2)=14.620,P<0.05)。观察组护理满意度为96.00%,高于参照组的84.00%,差异有统计学意义(χ^(2)=4.000,P<0.05)。结论老年慢性支气管炎优质化护理的效果较好,更能对患者的血气指标、肺通气功能进行改善,将患者的生命质量提升,并对患者的症状进行缓解,将患者的症状消退时间缩短,将患者的护理满意度提升。展开更多
文摘Objective: To investigate the effects of terbutaline combined with methylprednisolone on pulmonary function, blood gas analysis and inflammatory factors in patients with chronic obstructive pulmonary disease (COPD). Methods: A total of 100 patients with COPD were randomly divided into control group (n=50) and observation group (n=50) according to the lottery method. Both groups were treated with conventional therapy. On this basis, the control group was given inhalation of terbutaline. The observation group was given terbutaline inhalation and combination therapy with methylprednisolone. The changes of lung function, changes of blood gas analysis and inflammatory factors were measured before and after treatment in both groups. Results: There were no significant differences in lung function between the two groups before treatment. After treatment, the levels of FVC and FEV1 in both groups were significantly higher than those before treatment, and that of the observation group was higher than those of the control group. Before treatment, there was no significant difference between the two groups. After treatment, PaO2 levels in both groups were significantly higher than those before treatment, and that of the observation group was higher than those of the control group. After treatment, PaCO2 levels in both groups were significantly lower than those before treatment, and the observation group was lower than the control group after treatment. There were no significant differences in the levels of inflammatory factors between the two groups before treatment. After treatment, the levels of PCT and TNF-α in both groups were significantly lower than those before treatment, and those of the observation group was lower than those of the control group after treatment. Conclusion: The effect of Terbutaline combined with methylprednisolone treatment of COPD is better, which can significantly improve lung function, stable blood gas analysis, reduce the concentration of inflammatory factors, and be a potential effective treatment programs.
文摘目的探讨老年慢性支气管炎优质化护理的效果。方法回顾性选取2020年2月—2023年2月泉州市第一医院老年病院分院呼吸与危重症学科收治的100例老年慢性支气管炎患者的临床资料,依据护理方法分为观察组、参照组,各50例,观察组患者接受优质化护理,参照组患者接受常规化护理。统计分析两组血气指标、肺通气功能指标、生命质量、症状评分、护理依从性、护理满意度。结果观察组患者的二氧化碳分压(Partial Pressure of Carbon Dioxide,PaCO_(2))、症状评分低于参照组,血氧饱和度(Oxygen Saturation,SaO_(2))、氧分压(Oxygen Partial Pressure,PaO_(2))、第1秒用力呼气容积(Forced Expiratory Volume in the First Second,FEV1)、用力肺活量(Forced Vital Capacity,FVC)、认知、角色、情绪、躯体、社会均高于参照组,差异有统计学意义(P均<0.05)。观察组护理依从性为96.00%,高于参照组的66.00%,差异有统计学意义(χ^(2)=14.620,P<0.05)。观察组护理满意度为96.00%,高于参照组的84.00%,差异有统计学意义(χ^(2)=4.000,P<0.05)。结论老年慢性支气管炎优质化护理的效果较好,更能对患者的血气指标、肺通气功能进行改善,将患者的生命质量提升,并对患者的症状进行缓解,将患者的症状消退时间缩短,将患者的护理满意度提升。
