A novel framework for chaos and its impul-sive control in Chua's oscillator via time-delay feedback is presented.The exponential stability of impulsive control Chua's oscillator via time-delay feedback is considered...A novel framework for chaos and its impul-sive control in Chua's oscillator via time-delay feedback is presented.The exponential stability of impulsive control Chua's oscillator via time-delay feedback is considered,and some novel conditions are obtained.Then a novel impulsive controller design procedure is proposed.Simulation experiments are provided to demonstrate the feasibility and effectiveness of our method finally.展开更多
The thermal decoherence of harmonic oscillators is investigated here.The quantum system presented here is a one-dimensional oscillator with angular frequency,which is surrounded by a thermal bath of environmental osci...The thermal decoherence of harmonic oscillators is investigated here.The quantum system presented here is a one-dimensional oscillator with angular frequency,which is surrounded by a thermal bath of environmental oscillators.There are various environmental oscillators with different angular frequency(below an ultraviolet cutoff).At the beginning,the quantum system is a pure state and the environmental oscillators are in thermodynamic equilibrium with temperature.After a period,the system-environment interactions inspire significant decoherence of the quantum state.Such decoherence is displayed by explicit calculations of the purity and von Neumann entropy of the quantum system.It is worth noting that the decoherence could be significant even in the weak coupling and low temperature case due to the large amount of environmental degrees of freedom.Since the decoherence process is inspired between the quantum system and an ordinary thermal environment here,the thermal decoherence result is quite general.展开更多
The chimera states underlying many realistic dynamical processes have attracted ample attention in the area of dynamical systems.Here, we generalize the Kuramoto model with nonlocal coupling incorporating higher-order...The chimera states underlying many realistic dynamical processes have attracted ample attention in the area of dynamical systems.Here, we generalize the Kuramoto model with nonlocal coupling incorporating higher-order interactions encoded with simplicial complexes.Previous works have shown that higher-order interactions promote coherent states.However, we uncover the fact that the introduced higher-order couplings can significantly enhance the emergence of the incoherent state.Remarkably, we identify that the chimera states arise as a result of multi-attractors in dynamic states.Importantly, we review that the increasing higher-order interactions can significantly shape the emergent probability of chimera states.All the observed results can be well described in terms of the dimension reduction method.This study is a step forward in highlighting the importance of nonlocal higher-order couplings, which might provide control strategies for the occurrence of spatial-temporal patterns in networked systems.展开更多
This study deals with the analytical investigation of oscillatory squeeze film flow through a Brinkman viscoelastic Oldroyd-B fluid-saturated porous layer subject to two vertically harmonically oscillatory disks.The v...This study deals with the analytical investigation of oscillatory squeeze film flow through a Brinkman viscoelastic Oldroyd-B fluid-saturated porous layer subject to two vertically harmonically oscillatory disks.The validity of the present proposed analytical solutions is first demonstrated for the Newtonian fluids when bothΛ_(1)andΛ_(2)tend to zero by comparison with the previous literature.Results demonstrate that an increase in the elasticity parameterΛ_(1)correlates with a rise in axial velocities,indicating that the relaxation timeΛ_(1)facilitates enhanced squeeze flow.In the case of squeeze film flow in porous layers,low oscillating frequencies exert minimal effects on axial velocities,independent of variations in the viscoelasticity parameterΛ_(1).However,at higher oscillating frequencies,axial velocities escalate with increasing the viscoelasticity parameterΛ_(1).Furthermore,the retardation timeΛ_(2)of the viscoelastic fluid shows no significant effect on the axial velocity,regardless of oscillating frequency changes in both pure fluids and porous layers.展开更多
The dynamics of a solid spherical body in an oscillating liquid flow in a vertical axisymmetric channel of variable cross section is experimentally studied.It is shown that the oscillating liquid leads to the generati...The dynamics of a solid spherical body in an oscillating liquid flow in a vertical axisymmetric channel of variable cross section is experimentally studied.It is shown that the oscillating liquid leads to the generation of intense averaged flows in each of the channel segments.The intensity and direction of these flows depend on the dimensionless oscillating frequency.In the region of studied frequencies,the dynamics of the considered body is examined when the primary vortices emerging in the flow occupy the whole region in each segment.For a fixed frequency,an increase in the oscillation amplitude leads to a phase-inclusion holding effect,i.e.,the body occupies a quasi-stationary position in one of the cells of the vertical channel,while oscillating around its average position.It is also shown that the oscillating motion of a liquid column generates an averaged force acting on the body,the magnitude of which depends on the properties of the body and its position in the channel.The quasi-stationary position is determined by the relative density and size of the body,as well as the dimensionless frequency.The behavior of the body as a function of the amplitude and frequency of fluid oscillation and relative size is discussed in detail.Such findings may be used in the future to control the position of a phase inclusion and/or to strengthen mass transfer effects in a channel of variable cross section by means of fluid oscillations.展开更多
We show that an intrinsically nonlinear oscillator can always be transformed into a linear or harmonic oscillator by addition of a constant force, which shifts the equilibrium position of the oscillator.
We study the dynamics of a quantum dissipative system. Besides its linear coupling with a harmonic bath modelling the dissipation, we suppose that it is coupled with an oscillator with an interaction of the form s 2 x...We study the dynamics of a quantum dissipative system. Besides its linear coupling with a harmonic bath modelling the dissipation, we suppose that it is coupled with an oscillator with an interaction of the form s 2 x 2 . In our study, we integrate over the bath and the oscillator, extract the corresponding influence functionals and then solve the system’s sign problem. We apply the theory to the case of a double well and study the time evolution of the expectation value of the position.展开更多
Background:Shear stress-induced erythrocyte damage,namely hemolysis,is an important problem in the development of blood-contacting medical devices such as mechanical circulatory support devices.Computational fluid dyn...Background:Shear stress-induced erythrocyte damage,namely hemolysis,is an important problem in the development of blood-contacting medical devices such as mechanical circulatory support devices.Computational fluid dynamics simulation combined with hemolysis prediction models have been widely used to predict hemolysis.With the development of hemolysis prediction models,the new hemolysis prediction model requires more experimental data to verify.In addition,the difference of in vitro blood-shearing device also affect the accuracy of hemolysis prediction.Methods:To address these problems,a new in vitro blood-shearing device(vortex oscillator)was used to further verify the accuracy of the hemolysis prediction models,and to guide the optimal design of blood-contacting medical devices such as mechanical circulatory support devices.Firstly,the flow field information such as wall stress and velocity of the vortex oscillator under different speeds was analyzed.Secondly,different hemolysis prediction models were used to calculate hemolysis,and the predicted data was compared with the experimental data.Results and Conclusion:In this study,the flow field information inside the vortex oscillator at high rotational speeds was systematically investigated,and the prediction of hemolysis was carried out.The results showed that the predicted data of hemolysis was significantly different from the experimental data,which indicated that it was urgent to establish a standardized in vitro blood-shearing platform to provide a reference for accurate hemolysis prediction.展开更多
An accurate 1.08GHz CMOS LC voltage-controlled oscillator is implemented in a 0.35μm standard 2P4M CMOS process.A new convenient method of calculating oscillator period is presented.With this period calculation tech...An accurate 1.08GHz CMOS LC voltage-controlled oscillator is implemented in a 0.35μm standard 2P4M CMOS process.A new convenient method of calculating oscillator period is presented.With this period calculation technique,the frequency tuning curves agree well with the experiment.At a 3.3V supply,the LC-VCO measures a phase noise of -82.2dBc/Hz at a 10kHz frequency offset while dissipating 3.1mA current.The chip size is 0.86mm×0.82mm.展开更多
A 37. 5 MHz differential complementary metal oxide semiconductor (CMOS) crystal oscillator with low power and low phase noise for the radio frequency tuner of digital radio broadcasting digital radio mondiale (DRAM...A 37. 5 MHz differential complementary metal oxide semiconductor (CMOS) crystal oscillator with low power and low phase noise for the radio frequency tuner of digital radio broadcasting digital radio mondiale (DRAM) and digital audio broadcasting (DAB) systems is realized and characterized. The conventional cross-coupled n-type metal oxide semiconductor (NMOS) transistors are replaced by p-type metal oxide semiconductor (PMOS) transistors to decrease the phase noise in the core part of the crystal oscillator. A symmetry structure of the current mirror is adopted to increase the stability of direct current. The amplitude detecting circuit made up of a single- stage CMOS operational transconductance amplifier (OTA) and a simple amplitude detector is used to improve the current accuracy of the output signals. The chip is fabricated in a 0. 18- pxn CMOS process, and the total chip size is 0. 35 mm x 0. 3 mm. Under a supply voltage of 1.8 V, the measured power consumption is 3.6 mW including the output buffer for 50 testing loads. The proposed crystal oscillator exhibits a low phase noise of - 134. 7 dBc/Hz at 1-kHz offset from the center frequency of 37. 5 MHz.展开更多
A monolithic 10GHz LC voltage-controlled oscillator (VCO) is implemented in standard 0.25μm CMOS technology. The VCO adopts an optimized symmetric circular inductor with center-tap, an accumulation-mode MOS (A-MOS...A monolithic 10GHz LC voltage-controlled oscillator (VCO) is implemented in standard 0.25μm CMOS technology. The VCO adopts an optimized symmetric circular inductor with center-tap, an accumulation-mode MOS (A-MOS) varactor in series with a passive metal-isolator-metal capacitor (MIM-CAP) and a tail current source with an LC filter to operate with high-frequency and low-noise resulting in - 103.2dBc/Hz at 1MHz offset from carrier frequency of 10.2GHz and approximately 11.5% tuning range. With a 3.3V supply voltage, the core circuit consumes 9.9mW. The chip area is 0.67mm × 0.58mm.展开更多
A low phase noise quadrature oscillator using the new injection locked technique is proposed. The incident signal is directly injected into the common-source connection of the sub-harmonic oscillator. In principle, th...A low phase noise quadrature oscillator using the new injection locked technique is proposed. The incident signal is directly injected into the common-source connection of the sub-harmonic oscillator. In principle, the phase noise performance of the quadrature output is better than the sub-harmonic oscillator itself. The quadrature oscillator is implemented in a 0. 25μm CMOS process. Measurements show the proposed oscillator could achieve a phase noise of --130dBc/Hz at 1MHz offset from 1. 13GHz carrier while only drawing an 8.0mA current from the 2.5V power supply.展开更多
Aim To study a class of boundary value problem of hyperbolic partial functional differential equations with continuous deviating arguments. Methods An averaging technique was used. The multi dimensional problem was...Aim To study a class of boundary value problem of hyperbolic partial functional differential equations with continuous deviating arguments. Methods An averaging technique was used. The multi dimensional problem was reduced to a one dimensional oscillation problem for ordinary differential equations or inequalities. Results and Conclusion The known results of oscillation of solutions for a class of boundary value problem of hyperbolic partial functional differential equations with discrete deviating arguments are generalized, and the oscillatory criteria of solutions for such equation with two kinds of boundary value conditions are obtained.展开更多
This paper presents an efficient numerical scheme for calculating the periodic motion of a harmonically forced piecewise linear oscillator very accurately. The scheme is based on the shooting technique with the tradi...This paper presents an efficient numerical scheme for calculating the periodic motion of a harmonically forced piecewise linear oscillator very accurately. The scheme is based on the shooting technique with the traditional numerical Poincare mapping and its Jacobian replaced by the piecewise analytic ones. Thus, the scheme gets rid of the requirement of the current schemes for an assumed order of the oscillator trajectory passing through different linear regions. The numerical examples in the paper demonstrate that the new scheme, compared with the current schemes, enables one to cope with more complicated dynamics of harmonically forced piecewise linear oscillators.展开更多
Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Cu...Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Currently,studies have reported increased oscillation power in cases of levodopa-induced dyskinesia.However,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced dyskinesia.Furthermore,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is unclear.We found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s disease.Furthermore,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma flow.Administration of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum flow.However,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum direction.These findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia.展开更多
A new configuration for delay cells used in voltage controlled oscillators is presented. A jitter comparison between the source-coupled differential delay cell and the proposed CMOS inverter based delay cell is given....A new configuration for delay cells used in voltage controlled oscillators is presented. A jitter comparison between the source-coupled differential delay cell and the proposed CMOS inverter based delay cell is given. A new method to optimize loop parameters based on low-jitter in PLL is also introduced. A low-jitter 1.25GHz Serdes is implemented in a 0.35μm standard 2P3M CMOS process. The result shows that the RJ (random jitter) RMS of 1.25GHz data rate series output is 2. 3ps (0. 0015UI) and RJ (1 sigma) is 0. 0035UI. A phase noise measurement shows - 120dBc/Hz@100kHz at 1111100000 clock-pattern data out.展开更多
文摘A novel framework for chaos and its impul-sive control in Chua's oscillator via time-delay feedback is presented.The exponential stability of impulsive control Chua's oscillator via time-delay feedback is considered,and some novel conditions are obtained.Then a novel impulsive controller design procedure is proposed.Simulation experiments are provided to demonstrate the feasibility and effectiveness of our method finally.
文摘The thermal decoherence of harmonic oscillators is investigated here.The quantum system presented here is a one-dimensional oscillator with angular frequency,which is surrounded by a thermal bath of environmental oscillators.There are various environmental oscillators with different angular frequency(below an ultraviolet cutoff).At the beginning,the quantum system is a pure state and the environmental oscillators are in thermodynamic equilibrium with temperature.After a period,the system-environment interactions inspire significant decoherence of the quantum state.Such decoherence is displayed by explicit calculations of the purity and von Neumann entropy of the quantum system.It is worth noting that the decoherence could be significant even in the weak coupling and low temperature case due to the large amount of environmental degrees of freedom.Since the decoherence process is inspired between the quantum system and an ordinary thermal environment here,the thermal decoherence result is quite general.
基金Project supported by the National Natural Science Foundation of China (Grants Nos.12375031 and 11905068)the Natural Science Foundation of Fujian Province, China (Grant No.2023J01113)the Scientific Research Funds of Huaqiao University (Grant No.ZQN-810)。
文摘The chimera states underlying many realistic dynamical processes have attracted ample attention in the area of dynamical systems.Here, we generalize the Kuramoto model with nonlocal coupling incorporating higher-order interactions encoded with simplicial complexes.Previous works have shown that higher-order interactions promote coherent states.However, we uncover the fact that the introduced higher-order couplings can significantly enhance the emergence of the incoherent state.Remarkably, we identify that the chimera states arise as a result of multi-attractors in dynamic states.Importantly, we review that the increasing higher-order interactions can significantly shape the emergent probability of chimera states.All the observed results can be well described in terms of the dimension reduction method.This study is a step forward in highlighting the importance of nonlocal higher-order couplings, which might provide control strategies for the occurrence of spatial-temporal patterns in networked systems.
基金Project supported by the National Natural Science Foundation of China(No.12262026)the Natural Science Foundation of the Inner Mongolia Autonomous Region of China(No.2021MS01007)+1 种基金the Program for Innovative Research Team in Universities of Inner Mongolia Autonomous Region of China(No.NMGIRT2323)the Fundamental Research Funds for the Central Universities(Nos.2232022G-13,2232023G-13,and 2232024G-13)。
文摘This study deals with the analytical investigation of oscillatory squeeze film flow through a Brinkman viscoelastic Oldroyd-B fluid-saturated porous layer subject to two vertically harmonically oscillatory disks.The validity of the present proposed analytical solutions is first demonstrated for the Newtonian fluids when bothΛ_(1)andΛ_(2)tend to zero by comparison with the previous literature.Results demonstrate that an increase in the elasticity parameterΛ_(1)correlates with a rise in axial velocities,indicating that the relaxation timeΛ_(1)facilitates enhanced squeeze flow.In the case of squeeze film flow in porous layers,low oscillating frequencies exert minimal effects on axial velocities,independent of variations in the viscoelasticity parameterΛ_(1).However,at higher oscillating frequencies,axial velocities escalate with increasing the viscoelasticity parameterΛ_(1).Furthermore,the retardation timeΛ_(2)of the viscoelastic fluid shows no significant effect on the axial velocity,regardless of oscillating frequency changes in both pure fluids and porous layers.
文摘The dynamics of a solid spherical body in an oscillating liquid flow in a vertical axisymmetric channel of variable cross section is experimentally studied.It is shown that the oscillating liquid leads to the generation of intense averaged flows in each of the channel segments.The intensity and direction of these flows depend on the dimensionless oscillating frequency.In the region of studied frequencies,the dynamics of the considered body is examined when the primary vortices emerging in the flow occupy the whole region in each segment.For a fixed frequency,an increase in the oscillation amplitude leads to a phase-inclusion holding effect,i.e.,the body occupies a quasi-stationary position in one of the cells of the vertical channel,while oscillating around its average position.It is also shown that the oscillating motion of a liquid column generates an averaged force acting on the body,the magnitude of which depends on the properties of the body and its position in the channel.The quasi-stationary position is determined by the relative density and size of the body,as well as the dimensionless frequency.The behavior of the body as a function of the amplitude and frequency of fluid oscillation and relative size is discussed in detail.Such findings may be used in the future to control the position of a phase inclusion and/or to strengthen mass transfer effects in a channel of variable cross section by means of fluid oscillations.
文摘We show that an intrinsically nonlinear oscillator can always be transformed into a linear or harmonic oscillator by addition of a constant force, which shifts the equilibrium position of the oscillator.
文摘We study the dynamics of a quantum dissipative system. Besides its linear coupling with a harmonic bath modelling the dissipation, we suppose that it is coupled with an oscillator with an interaction of the form s 2 x 2 . In our study, we integrate over the bath and the oscillator, extract the corresponding influence functionals and then solve the system’s sign problem. We apply the theory to the case of a double well and study the time evolution of the expectation value of the position.
基金supported by 2023 Kunshan Science and Technology Association youth science and technology talent lifting project(Project name:Mechanism study of mechanical damage of coagulation factor VWF based on in vitro blood-shearing experimental platform).
文摘Background:Shear stress-induced erythrocyte damage,namely hemolysis,is an important problem in the development of blood-contacting medical devices such as mechanical circulatory support devices.Computational fluid dynamics simulation combined with hemolysis prediction models have been widely used to predict hemolysis.With the development of hemolysis prediction models,the new hemolysis prediction model requires more experimental data to verify.In addition,the difference of in vitro blood-shearing device also affect the accuracy of hemolysis prediction.Methods:To address these problems,a new in vitro blood-shearing device(vortex oscillator)was used to further verify the accuracy of the hemolysis prediction models,and to guide the optimal design of blood-contacting medical devices such as mechanical circulatory support devices.Firstly,the flow field information such as wall stress and velocity of the vortex oscillator under different speeds was analyzed.Secondly,different hemolysis prediction models were used to calculate hemolysis,and the predicted data was compared with the experimental data.Results and Conclusion:In this study,the flow field information inside the vortex oscillator at high rotational speeds was systematically investigated,and the prediction of hemolysis was carried out.The results showed that the predicted data of hemolysis was significantly different from the experimental data,which indicated that it was urgent to establish a standardized in vitro blood-shearing platform to provide a reference for accurate hemolysis prediction.
文摘An accurate 1.08GHz CMOS LC voltage-controlled oscillator is implemented in a 0.35μm standard 2P4M CMOS process.A new convenient method of calculating oscillator period is presented.With this period calculation technique,the frequency tuning curves agree well with the experiment.At a 3.3V supply,the LC-VCO measures a phase noise of -82.2dBc/Hz at a 10kHz frequency offset while dissipating 3.1mA current.The chip size is 0.86mm×0.82mm.
基金The National Natural Science Foundation of China(No. 61106024)the Specialized Research Fund for the Doctoral Program of Higher Education (No. 20090092120012)the Science and Technology Program of South east University (No. KJ2010402)
文摘A 37. 5 MHz differential complementary metal oxide semiconductor (CMOS) crystal oscillator with low power and low phase noise for the radio frequency tuner of digital radio broadcasting digital radio mondiale (DRAM) and digital audio broadcasting (DAB) systems is realized and characterized. The conventional cross-coupled n-type metal oxide semiconductor (NMOS) transistors are replaced by p-type metal oxide semiconductor (PMOS) transistors to decrease the phase noise in the core part of the crystal oscillator. A symmetry structure of the current mirror is adopted to increase the stability of direct current. The amplitude detecting circuit made up of a single- stage CMOS operational transconductance amplifier (OTA) and a simple amplitude detector is used to improve the current accuracy of the output signals. The chip is fabricated in a 0. 18- pxn CMOS process, and the total chip size is 0. 35 mm x 0. 3 mm. Under a supply voltage of 1.8 V, the measured power consumption is 3.6 mW including the output buffer for 50 testing loads. The proposed crystal oscillator exhibits a low phase noise of - 134. 7 dBc/Hz at 1-kHz offset from the center frequency of 37. 5 MHz.
文摘A monolithic 10GHz LC voltage-controlled oscillator (VCO) is implemented in standard 0.25μm CMOS technology. The VCO adopts an optimized symmetric circular inductor with center-tap, an accumulation-mode MOS (A-MOS) varactor in series with a passive metal-isolator-metal capacitor (MIM-CAP) and a tail current source with an LC filter to operate with high-frequency and low-noise resulting in - 103.2dBc/Hz at 1MHz offset from carrier frequency of 10.2GHz and approximately 11.5% tuning range. With a 3.3V supply voltage, the core circuit consumes 9.9mW. The chip area is 0.67mm × 0.58mm.
文摘A low phase noise quadrature oscillator using the new injection locked technique is proposed. The incident signal is directly injected into the common-source connection of the sub-harmonic oscillator. In principle, the phase noise performance of the quadrature output is better than the sub-harmonic oscillator itself. The quadrature oscillator is implemented in a 0. 25μm CMOS process. Measurements show the proposed oscillator could achieve a phase noise of --130dBc/Hz at 1MHz offset from 1. 13GHz carrier while only drawing an 8.0mA current from the 2.5V power supply.
文摘Aim To study a class of boundary value problem of hyperbolic partial functional differential equations with continuous deviating arguments. Methods An averaging technique was used. The multi dimensional problem was reduced to a one dimensional oscillation problem for ordinary differential equations or inequalities. Results and Conclusion The known results of oscillation of solutions for a class of boundary value problem of hyperbolic partial functional differential equations with discrete deviating arguments are generalized, and the oscillatory criteria of solutions for such equation with two kinds of boundary value conditions are obtained.
文摘This paper presents an efficient numerical scheme for calculating the periodic motion of a harmonically forced piecewise linear oscillator very accurately. The scheme is based on the shooting technique with the traditional numerical Poincare mapping and its Jacobian replaced by the piecewise analytic ones. Thus, the scheme gets rid of the requirement of the current schemes for an assumed order of the oscillator trajectory passing through different linear regions. The numerical examples in the paper demonstrate that the new scheme, compared with the current schemes, enables one to cope with more complicated dynamics of harmonically forced piecewise linear oscillators.
基金supported by the National Natural Science Foundation of China,No.82071254(to WZ).
文摘Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Currently,studies have reported increased oscillation power in cases of levodopa-induced dyskinesia.However,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced dyskinesia.Furthermore,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is unclear.We found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s disease.Furthermore,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma flow.Administration of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum flow.However,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum direction.These findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia.
文摘A new configuration for delay cells used in voltage controlled oscillators is presented. A jitter comparison between the source-coupled differential delay cell and the proposed CMOS inverter based delay cell is given. A new method to optimize loop parameters based on low-jitter in PLL is also introduced. A low-jitter 1.25GHz Serdes is implemented in a 0.35μm standard 2P3M CMOS process. The result shows that the RJ (random jitter) RMS of 1.25GHz data rate series output is 2. 3ps (0. 0015UI) and RJ (1 sigma) is 0. 0035UI. A phase noise measurement shows - 120dBc/Hz@100kHz at 1111100000 clock-pattern data out.