Objective:To observe the clinical efficacy of Chuanxiong Hualiu Mixture in the treatment of blood stasis and phlegm stagnation type of ovarian cyst and the effects on physical and chemical indicators.Methods: A total ...Objective:To observe the clinical efficacy of Chuanxiong Hualiu Mixture in the treatment of blood stasis and phlegm stagnation type of ovarian cyst and the effects on physical and chemical indicators.Methods: A total of 80 patients with blood stasis and phlegm stagnation type of ovarian cyst were randomly divided into two groups, research group (n=40) took Chuanxiong Hualiu Mixture, control group (n=40) took Guizhi Fuling Capsule, 3 months was a course of treatment, and the curative effect was compared between two groups.Results:(1) The overall response rate of Chuanxiong Hualiu mixture group after 3 months of treatment was 82.5%, that of Guizhi Fuling Capsule group was 62.5%, the overall response rate of Chuanxiong Hualiu mixture group was higher than that of control group, and the difference was statistically significant;(2) before and after treatment, sex hormone and hemorheology index E2 of both groups decreased significantly, whole blood viscosity, whole blood reduced viscosity and plasma viscosity decreased significantly, the results were statistically significant, but there was no difference between two groups;(3) rank sum test of TCM symptom efficacy between two groups before and after treatment showed that the overall response rate of Chuanxiong Hualiu mixture group was 95%, the overall response rate of Guizhi Fuling Capsule group was 85%, the overall response rate of research group was better than that of control group, and the difference was statistically significant.Conclusion:Chuanxiong Hualiu mixture has good curative effect for the treatment of ovarian cyst, it can effectively improve the patients' blood stasis and phlegm stagnation constitution, and its mechanism of action is associated with lowering estrogen levels and improving hemorrheology.展开更多
Chuanxiong Antiasthma Mixture is a prescription for bronchial asthma which we have adoptedin the clinic for many years. The results of the animal experiment showed that it lias the function of relaxing ,the isolated b...Chuanxiong Antiasthma Mixture is a prescription for bronchial asthma which we have adoptedin the clinic for many years. The results of the animal experiment showed that it lias the function of relaxing ,the isolated bronchial smooth muscle spasm of the animal, lowering the experimented animal's asthma inci-dence and mortality. On the basis ot these results, we have expanded our clinical observation samples set-ting up the Chuanxiong antiasthma group : 100 cases and the control group : 50 cases. The results showed thatthe mixtore can apparently increase the ratio of 1 second forcoful expiration volume/ forceful vital capacity(FEV1%) and redce the value of thromboxane B2. The total effective rate is 92 % which is obviously superi-or than the control group (P<0. 05) . It suggests that the mixture has the antagonistic effect toward the syn-thesis and release of thromboxane B2. Also it has the fonction of relaxing the smcoth muscle and improve thepulmonary fonction.展开更多
文摘Objective:To observe the clinical efficacy of Chuanxiong Hualiu Mixture in the treatment of blood stasis and phlegm stagnation type of ovarian cyst and the effects on physical and chemical indicators.Methods: A total of 80 patients with blood stasis and phlegm stagnation type of ovarian cyst were randomly divided into two groups, research group (n=40) took Chuanxiong Hualiu Mixture, control group (n=40) took Guizhi Fuling Capsule, 3 months was a course of treatment, and the curative effect was compared between two groups.Results:(1) The overall response rate of Chuanxiong Hualiu mixture group after 3 months of treatment was 82.5%, that of Guizhi Fuling Capsule group was 62.5%, the overall response rate of Chuanxiong Hualiu mixture group was higher than that of control group, and the difference was statistically significant;(2) before and after treatment, sex hormone and hemorheology index E2 of both groups decreased significantly, whole blood viscosity, whole blood reduced viscosity and plasma viscosity decreased significantly, the results were statistically significant, but there was no difference between two groups;(3) rank sum test of TCM symptom efficacy between two groups before and after treatment showed that the overall response rate of Chuanxiong Hualiu mixture group was 95%, the overall response rate of Guizhi Fuling Capsule group was 85%, the overall response rate of research group was better than that of control group, and the difference was statistically significant.Conclusion:Chuanxiong Hualiu mixture has good curative effect for the treatment of ovarian cyst, it can effectively improve the patients' blood stasis and phlegm stagnation constitution, and its mechanism of action is associated with lowering estrogen levels and improving hemorrheology.
文摘Chuanxiong Antiasthma Mixture is a prescription for bronchial asthma which we have adoptedin the clinic for many years. The results of the animal experiment showed that it lias the function of relaxing ,the isolated bronchial smooth muscle spasm of the animal, lowering the experimented animal's asthma inci-dence and mortality. On the basis ot these results, we have expanded our clinical observation samples set-ting up the Chuanxiong antiasthma group : 100 cases and the control group : 50 cases. The results showed thatthe mixtore can apparently increase the ratio of 1 second forcoful expiration volume/ forceful vital capacity(FEV1%) and redce the value of thromboxane B2. The total effective rate is 92 % which is obviously superi-or than the control group (P<0. 05) . It suggests that the mixture has the antagonistic effect toward the syn-thesis and release of thromboxane B2. Also it has the fonction of relaxing the smcoth muscle and improve thepulmonary fonction.
