Alternating chemotherapy and fractionated radiotherapy were carried out in 32 patients with surgically proven unresectable primary liver cancer (PLC).After initial surgical intervention of hepatic artery ligation and ...Alternating chemotherapy and fractionated radiotherapy were carried out in 32 patients with surgically proven unresectable primary liver cancer (PLC).After initial surgical intervention of hepatic artery ligation and cannulation,the tumor war localized with silver clips.The cisplatin 20 mg was infused via a hepatic artery catheter per day on the first 3 consecutive days.Fractionated radiation(18MV straight linear accelerator)of 250 cGy,twice a day with an interval of 6 hours,was then followed on the 8th,9th and 10th days.The cycle was repeated 3 or 4 times.The shrinkage of tumors and decrease of AFP level were observed in 100%(32/32)and 5% (19/21)of the patients respectively.A second-stage resection was done in 37.5%(12/32)of the patients.The 1-,3- and 5-year survival rates after resection were 96.7% ,67.5% and 67. 5 % respectively.It is suggested that this modality is a choice of therapies which can convert some unresectable large PLC to resectable ones.展开更多
NUT(nuclear protein of the testis)midline carcinoma(NMC)is a rare malignant and poorly differentiated squamous cell tumor that typically presents in midline structures of the head,neck and mediastinum with high degree...NUT(nuclear protein of the testis)midline carcinoma(NMC)is a rare malignant and poorly differentiated squamous cell tumor that typically presents in midline structures of the head,neck and mediastinum with high degree of invasion and mortality,which occurs at any age,especially in teenagers and young people.We report a case of NMC presented as a mediastinal tumor.A 14-year-old female patient who presentedwith progressive dyspnea,cough with expectoration,and right pleural effusion and mediastinal space-occupying.Cisplatin(DDP)-based chemotherapy was performed.The prognosis is bad with an overall survival of 3 months.展开更多
Objective:To evaluate the efficacy and side effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer(NSCLC).Methods:Sixty-three patients with stageⅢB andⅣNSCLC hospitalized ...Objective:To evaluate the efficacy and side effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer(NSCLC).Methods:Sixty-three patients with stageⅢB andⅣNSCLC hospitalized from October 2001 to October 2008 were enrolled and assigned to two groups using a randomizing digital table,with 33 patients in the treatment group and 30 in the control group. They were all treated with the Navelbine and Cisplatin(NP) chemotherapy,but to the treatment group the Chinese drugs Sh...展开更多
文摘Alternating chemotherapy and fractionated radiotherapy were carried out in 32 patients with surgically proven unresectable primary liver cancer (PLC).After initial surgical intervention of hepatic artery ligation and cannulation,the tumor war localized with silver clips.The cisplatin 20 mg was infused via a hepatic artery catheter per day on the first 3 consecutive days.Fractionated radiation(18MV straight linear accelerator)of 250 cGy,twice a day with an interval of 6 hours,was then followed on the 8th,9th and 10th days.The cycle was repeated 3 or 4 times.The shrinkage of tumors and decrease of AFP level were observed in 100%(32/32)and 5% (19/21)of the patients respectively.A second-stage resection was done in 37.5%(12/32)of the patients.The 1-,3- and 5-year survival rates after resection were 96.7% ,67.5% and 67. 5 % respectively.It is suggested that this modality is a choice of therapies which can convert some unresectable large PLC to resectable ones.
基金This study was funded by Enshi Prefecture Science and Technology Program Research and Development Project(No.2019000040).
文摘NUT(nuclear protein of the testis)midline carcinoma(NMC)is a rare malignant and poorly differentiated squamous cell tumor that typically presents in midline structures of the head,neck and mediastinum with high degree of invasion and mortality,which occurs at any age,especially in teenagers and young people.We report a case of NMC presented as a mediastinal tumor.A 14-year-old female patient who presentedwith progressive dyspnea,cough with expectoration,and right pleural effusion and mediastinal space-occupying.Cisplatin(DDP)-based chemotherapy was performed.The prognosis is bad with an overall survival of 3 months.
基金Supported by the Grant from Project of Beijing Traditional Chinese Medicine Bureau(No.JJ2001-12)
文摘Objective:To evaluate the efficacy and side effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer(NSCLC).Methods:Sixty-three patients with stageⅢB andⅣNSCLC hospitalized from October 2001 to October 2008 were enrolled and assigned to two groups using a randomizing digital table,with 33 patients in the treatment group and 30 in the control group. They were all treated with the Navelbine and Cisplatin(NP) chemotherapy,but to the treatment group the Chinese drugs Sh...