BACKGROUND Intractable postherpetic neuralgia(PHN)can be difficult to manage even with aggressive multimodal therapies.Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may ben...BACKGROUND Intractable postherpetic neuralgia(PHN)can be difficult to manage even with aggressive multimodal therapies.Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may benefit from an intrathecal drug delivery system(IDDS).For craniofacial neuropathic pain,the traditional approach has been to place the intrathecal catheter tip below the level of the cranial nerve root entry zones,which may lead to insufficient analgesia.CASE SUMMARY We describe a 69-year-old man with a 1-year history of PHN after developing a vesicular rash in the ophthalmic division of cranial nerve V(trigeminal nerve)distribution.The pain was rated 7-8 at rest and 9-10 at breakthrough pain(BTP)on a numeric rating scale.Despite receiving aggressive multimodal therapies including large doses of oral analgesics(gabapentin 150 mg q12 h,oxycodone 5 mg/acetaminophen 325 mg q6 h,and lidocaine 5%patch 700 mg q12 h)and sphenopalatine ganglion block,there was no relief of pain.Subsequently,the patient elected to have an implantable IDDS with the catheter tip placed at the interpeduncular cistern.The frequency of BTP episodes decreased.The patient’s continuous daily dose was adjusted to 0.032 mg/d after 3 mo of follow-up and stopped 5 mo later.He did not report pain or other discomfort at outpatient follow-up 6 mo and 1 year after stopping intracisternal hydromorphone.CONCLUSION The use of interpeduncular cistern intrathecal infusion with low-dose hydromorphone by IDDS may be effective for severe craniofacial PHN.展开更多
Rainwater harvesting(RWH)systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries.However,due to various reasons,there are several sources ...Rainwater harvesting(RWH)systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries.However,due to various reasons,there are several sources of contamination in the rainwater cistern systems.Dissolved chemicals from the roofing,storage,and conveyance materials,together with the suspended particulate matter from the airborne,are examples of water contamination.In this work,the water quality monitoring system has been designed and implemented.Chemical and physical parameters of water samples were collected from three locations using a data acquisition(DAQ)system and rainwater quality was analyzed using Water Pollution Index(WPI).Results obtained from three locations have been presented.展开更多
BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberc...BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberculomas only in the cistern are extremely rare with only a few reported cases in the literature.We describe a unique case of isolated tuberculoma in the suprasellar cistern,with only right ocular motility disorder and upper eyelid ptosis.CASE SUMMARY A 5-year-old boy without any medical history presented with right ocular motility disorder and upper eyelid ptosis one month ago.He had no history of fever,headache,vomiting,convulsions,or limb weakness.Neurological examination showed right third cranial nerve palsy with restrictions of eye movements and ptosis,pupil dilation and negative light reflex.Imaging suggested a spaceoccupying lesion in the suprasellar cistern with calcification and ring-enhancement.Moreover,no Mycobacterium tuberculosis was found in cerebrospinal fluid by polymerase chain reaction(PCR).The lesion was initially diagnosed as a tumor,while postoperative pathology combined with PCR indicated tuberculoma.The patient continued postoperative anti-tuberculosis treatment.At present,the patient's condition is stable and the symptoms are partially relieved compared with those before surgery.CONCLUSION This case confirmed that isolated intracranial tuberculoma can occur in the suprasellar cistern.Therefore,for space-occupying lesions in the suprasellar cistern,tuberculoma should be included in the differential diagnosis even if there is no history or indication of tuberculosis infection.展开更多
This article reports on a case study of the research and development of a new tool to assist in the design of rainwater cisterns. A rainwater cistern is a way to improve wildlife habitat because it can be situated in ...This article reports on a case study of the research and development of a new tool to assist in the design of rainwater cisterns. A rainwater cistern is a way to improve wildlife habitat because it can be situated in locations that do not have natural water sources, such as streams or wells that can supply water for storage. However, the design and sizing of such a system can be challenging because a number of constantly varying factors must be considered, such as changing precipitation patterns, the evaporative losses from the cistern and </span><span style="font-family:Verdana;">animal water consumption. No standardized sizing methodology currently</span><span style="font-family:Verdana;"> exists for designing wildlife rainwater cisterns. In this article we present a new method for assisting in optimally sizing a rainwater cistern. We discuss how we implemented the quantitative portion of this methodology into a new Excel? model called CISMOD, which we configured for general use by wildlife professionals. We describe the methodology for designing a rainwater cistern based on standard engineering techniques. We then present and discuss our experience in applying the model to design two rainwater cisterns in an area of the Jemez Mountains in northern New Mexico, USA. The CISMOD model and a user manual are available at no cost for wildlife professionals.展开更多
Objective To study microanatomy features and clinical significance of ambient cisterns and their arachnoidal membranes in detail. Methods Ambient cisterns including their shapes,borders,contents and arachnoidal membra...Objective To study microanatomy features and clinical significance of ambient cisterns and their arachnoidal membranes in detail. Methods Ambient cisterns including their shapes,borders,contents and arachnoidal membranes were observed in 20 cadaveric brains using an operating microscope. Results The展开更多
Objective: To explore prospectively the relationship between the state of perimesencephalic cistern and the degree of deformation of the midbrain on CT scanning and the outcome of the patients with acute craniocerebra...Objective: To explore prospectively the relationship between the state of perimesencephalic cistern and the degree of deformation of the midbrain on CT scanning and the outcome of the patients with acute craniocerebral injury.Methods: The CT scan features including the states of perimesencephalic cisterns, the deformations of the midbrain and the ratios of the occipitofrontal diameter and the transverse diameter of the midbrain of 132 cases were measured. The GOS of the patients 3 months after trauma were regarded as outcome. Conclusions: The state of the compressed perimesencephalic cistern (<1 mm) and the deformation of the midbrain 05- significantly indicate unfavorable outcome of the patients with acute craniocerebral injury.展开更多
基金Supported by National Natural Science Foundation of China,No.81891004Tianjin Natural Science Foundation of China,No.21JCQNJC01140.
文摘BACKGROUND Intractable postherpetic neuralgia(PHN)can be difficult to manage even with aggressive multimodal therapies.Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may benefit from an intrathecal drug delivery system(IDDS).For craniofacial neuropathic pain,the traditional approach has been to place the intrathecal catheter tip below the level of the cranial nerve root entry zones,which may lead to insufficient analgesia.CASE SUMMARY We describe a 69-year-old man with a 1-year history of PHN after developing a vesicular rash in the ophthalmic division of cranial nerve V(trigeminal nerve)distribution.The pain was rated 7-8 at rest and 9-10 at breakthrough pain(BTP)on a numeric rating scale.Despite receiving aggressive multimodal therapies including large doses of oral analgesics(gabapentin 150 mg q12 h,oxycodone 5 mg/acetaminophen 325 mg q6 h,and lidocaine 5%patch 700 mg q12 h)and sphenopalatine ganglion block,there was no relief of pain.Subsequently,the patient elected to have an implantable IDDS with the catheter tip placed at the interpeduncular cistern.The frequency of BTP episodes decreased.The patient’s continuous daily dose was adjusted to 0.032 mg/d after 3 mo of follow-up and stopped 5 mo later.He did not report pain or other discomfort at outpatient follow-up 6 mo and 1 year after stopping intracisternal hydromorphone.CONCLUSION The use of interpeduncular cistern intrathecal infusion with low-dose hydromorphone by IDDS may be effective for severe craniofacial PHN.
文摘Rainwater harvesting(RWH)systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries.However,due to various reasons,there are several sources of contamination in the rainwater cistern systems.Dissolved chemicals from the roofing,storage,and conveyance materials,together with the suspended particulate matter from the airborne,are examples of water contamination.In this work,the water quality monitoring system has been designed and implemented.Chemical and physical parameters of water samples were collected from three locations using a data acquisition(DAQ)system and rainwater quality was analyzed using Water Pollution Index(WPI).Results obtained from three locations have been presented.
文摘BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberculomas only in the cistern are extremely rare with only a few reported cases in the literature.We describe a unique case of isolated tuberculoma in the suprasellar cistern,with only right ocular motility disorder and upper eyelid ptosis.CASE SUMMARY A 5-year-old boy without any medical history presented with right ocular motility disorder and upper eyelid ptosis one month ago.He had no history of fever,headache,vomiting,convulsions,or limb weakness.Neurological examination showed right third cranial nerve palsy with restrictions of eye movements and ptosis,pupil dilation and negative light reflex.Imaging suggested a spaceoccupying lesion in the suprasellar cistern with calcification and ring-enhancement.Moreover,no Mycobacterium tuberculosis was found in cerebrospinal fluid by polymerase chain reaction(PCR).The lesion was initially diagnosed as a tumor,while postoperative pathology combined with PCR indicated tuberculoma.The patient continued postoperative anti-tuberculosis treatment.At present,the patient's condition is stable and the symptoms are partially relieved compared with those before surgery.CONCLUSION This case confirmed that isolated intracranial tuberculoma can occur in the suprasellar cistern.Therefore,for space-occupying lesions in the suprasellar cistern,tuberculoma should be included in the differential diagnosis even if there is no history or indication of tuberculosis infection.
文摘This article reports on a case study of the research and development of a new tool to assist in the design of rainwater cisterns. A rainwater cistern is a way to improve wildlife habitat because it can be situated in locations that do not have natural water sources, such as streams or wells that can supply water for storage. However, the design and sizing of such a system can be challenging because a number of constantly varying factors must be considered, such as changing precipitation patterns, the evaporative losses from the cistern and </span><span style="font-family:Verdana;">animal water consumption. No standardized sizing methodology currently</span><span style="font-family:Verdana;"> exists for designing wildlife rainwater cisterns. In this article we present a new method for assisting in optimally sizing a rainwater cistern. We discuss how we implemented the quantitative portion of this methodology into a new Excel? model called CISMOD, which we configured for general use by wildlife professionals. We describe the methodology for designing a rainwater cistern based on standard engineering techniques. We then present and discuss our experience in applying the model to design two rainwater cisterns in an area of the Jemez Mountains in northern New Mexico, USA. The CISMOD model and a user manual are available at no cost for wildlife professionals.
文摘Objective To study microanatomy features and clinical significance of ambient cisterns and their arachnoidal membranes in detail. Methods Ambient cisterns including their shapes,borders,contents and arachnoidal membranes were observed in 20 cadaveric brains using an operating microscope. Results The
文摘Objective: To explore prospectively the relationship between the state of perimesencephalic cistern and the degree of deformation of the midbrain on CT scanning and the outcome of the patients with acute craniocerebral injury.Methods: The CT scan features including the states of perimesencephalic cisterns, the deformations of the midbrain and the ratios of the occipitofrontal diameter and the transverse diameter of the midbrain of 132 cases were measured. The GOS of the patients 3 months after trauma were regarded as outcome. Conclusions: The state of the compressed perimesencephalic cistern (<1 mm) and the deformation of the midbrain 05- significantly indicate unfavorable outcome of the patients with acute craniocerebral injury.
