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Drivers for Inter-city Innovation Networks Across Chinese Cities:Modelling Physical Versus Intangible Effects
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作者 GAO Yujie SCHERNGELL Thomas NEULÄNDTNER Martina 《Chinese Geographical Science》 SCIE CSCD 2024年第4期706-721,共16页
Cross-region innovation is widely recognized as an important source of the long-term regional innovation capacity.In the recent past,a growing number of studies has investigated the network structure and mechanisms of... Cross-region innovation is widely recognized as an important source of the long-term regional innovation capacity.In the recent past,a growing number of studies has investigated the network structure and mechanisms of cross-region innovation collaboration in various contexts.However,existing research mainly focuses on physical effects,such as geographical distance and high-speed railway connections.These studies ignore the intangible drivers in a changing environment,the more digitalized economy and the increasingly solidified innovation network structure.Thus,the focus of this study is on estimating determinants of innovation networks,especially on intangible drivers,which have been largely neglected so far.Using city-level data of Chinese patents(excluding Hong Kong,Macao,and Taiwan Province of China),we trace innovation networks across Chinese cities over a long period of time.By integrating a measure on Information and Communications Technology(ICT)development gap and network structural effects into the general proximity framework,this paper explores the changing mechanisms of Chinese innovation networks from a new perspective.The results show that the structure of cross-region innovation networks has changed in China.As mechanisms behind this development,the results confirm the increasingly important role of intangible drivers in Chinese inter-city innovation collaboration when controlling for effects of physical proximity,such as geographical distance.Since digitalization and coordinated development are the mainstream trends in China and other developing countries,these countries'inter-city innovation collaboration patterns will witness dramatic changes under the influence of intangible drivers. 展开更多
关键词 inter-city innovation network co-patents information and communications technology development network structural effect spatial interaction model China
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Are cities greener because of innovation?Independent innovation policy and green economic efficiency
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作者 Zhuoji Zheng Xueqin Li +3 位作者 Mengjie Yu Yuan Li Xianfeng Han Yuping Yin 《Chinese Journal of Population,Resources and Environment》 2024年第2期118-126,共9页
The national independent innovation demonstration zone(NIIDZ)is an independent innovation policy that plays a crucial role in implementing strategies.Given the importance of the NIIDZ,this study uses panel data of 278... The national independent innovation demonstration zone(NIIDZ)is an independent innovation policy that plays a crucial role in implementing strategies.Given the importance of the NIIDZ,this study uses panel data of 278 prefecture-level cities in China from 2006 to 2020 and empirically examines the effect and internal mechanism of the NIIDZ on green economic efficiency(GEE)using the difference-in-difference model(DID).The results show that the NIIDZ effectively enhances the growth of GEE,and the results remain valid through several robustness tests,such as year-by-year propensity score matching.The transmission mechanism suggests that the NIIDZ indirectly drives GEE by accelerating scientific and technological investment,promoting talent concentration,and optimizing the industrial structure.Moreover,heterogeneity analysis reveals that the promotion effect of the NIIDZ on GEE is more prominent in the eastern region and high green development level areas.The study’s findings can serve as a reference for China to further utilize the policy effectiveness of the NIIDZ and accelerate the high-quality development of the green economy in the future. 展开更多
关键词 National innovation independent demonstration Zone(NIIDZ) Green economy efficiency(GEE) Difference-in-difference model(DID)
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Understanding the Relationship Between Shrinking Cities and Land Prices:Spatial Pattern,Effectiveness,and Policy Implications 被引量:1
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作者 WANG Xiaohui PENG Li +1 位作者 HUANG Kexin DENG Wei 《Chinese Geographical Science》 SCIE CSCD 2024年第1期1-18,共18页
Urban shrinkage has emerged as a widespread phenomenon globally and has a significant impact on land,particularly in terms of land use and price.This study focuses on 2851 county-level cities in China in 2005–2018(ex... Urban shrinkage has emerged as a widespread phenomenon globally and has a significant impact on land,particularly in terms of land use and price.This study focuses on 2851 county-level cities in China in 2005–2018(excluding Hong Kong,Macao,Taiwan,and‘no data’areas in Qinhai-Tibet Plateau)as the fundamental units of analysis.By employing nighttime light(NTL)data to identify shrinking cities,the propensity score matching(PSM)model was used to quantitatively examine the impact of shrinking cities on land prices,and evaluate the magnitude of this influence.The findings demonstrate the following:1)there were 613 shrinking cities in China,with moderate shrinkage being the most prevalent and severe shrinkage being the least.2)Regional disparities are evident in the spatial distribution of shrinking cities,especially in areas with diverse terrain.3)The spatial pattern of land price exhibits a significant correlated to the economic and administrative levels.4)Shrinking cities significantly negatively impact on the overall land price(ATT=–0.1241,P<0.05).However,the extent of the effect varies significantly among different spatial regions.This study contributes novel insights into the investigation of land prices and shrinking cities,ultimately serving as a foundation for government efforts to promote the sustainable development of urban areas. 展开更多
关键词 shrinking cities land price propensity score matching(PSM) relative effectiveness China
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Addressing inclusion,innovation,and sustainability challenges through the lens of economic geography:Introducing the hierarchical regional innovation system
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作者 Iván Tartaruga Fernanda Sperotto Luís Carvalho 《Geography and Sustainability》 CSCD 2024年第1期1-12,共12页
The world is facing dramatic challenges related to environmental sustainability at an accelerating pace.In this context,the field of economic geography(EG)has been playing an important role in understanding both the s... The world is facing dramatic challenges related to environmental sustainability at an accelerating pace.In this context,the field of economic geography(EG)has been playing an important role in understanding both the socioeconomic and technological dimensions of these challenges,as it deals with a variety of complementary notions and perspectives.Departing from this lens,our aim is to explore a conceptual framework that can help us to understand environmental changes relating to multi-dimensional territorial development,notably in eco-nomic contexts where inequality is high,and stratification based on hierarchies regulate social and economic life.Based on the territory concept,we propose the original notion of a hierarchical regional innovation system(HRIS)that emphasises the pervasive role of hierarchies(powers)in regional innovation systems and illustrate its value with evidence and case studies from extant literature on sustainability transitions.The HRIS can help us understand and promote development paths considering the contribution of inclusive eco-innovations(another original conceptual amalgam).Through some empirical cases from other studies in low-carbon transitions,we show the application of the HRIS(and inclusive eco-innovation)framework.In conclusion,we provide incen-tives to explore new regional innovation systems,alongside the HRIS,adapted to different regions worldwide and centred on the inclusiveness of people and places. 展开更多
关键词 Inclusive eco-innovation Inclusive innovation Hierarchical regional innovation system(HRIS) Territorial development Sustainable development Sustainability transitions
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A Study on the Symbol-Based Narrative in the International Communication of Cities
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作者 Zhang Li 《Contemporary Social Sciences》 2024年第4期41-52,共12页
Cultural symbols,a manifestation of cities’cultural resources,are not only signs that frame concepts but also forms that express meanings.Exploring the international communication of cities from the perspective of sy... Cultural symbols,a manifestation of cities’cultural resources,are not only signs that frame concepts but also forms that express meanings.Exploring the international communication of cities from the perspective of symbols,this paper analyzes in depth how cities create their cultural symbols in the dynamic process of international communication in an era of symbol-based digital media,and how they develop their narratives and explain meanings through the dissemination of symbols when telling their stories to international audiences,thus enhancing the efficiency and effectiveness of their international communication efforts. 展开更多
关键词 cities international communication cultural symbols city narratives
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Research on Innovation-Driven Expansion of Regional OFDI: New Evidence From a Business Environment Perspective
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作者 Duan Longlong Li Qingyi 《Contemporary Social Sciences》 2024年第1期75-98,共24页
This paper investigates the impact of provincial innovation-driven efficiency on the expansion of regional Outward Foreign Direct Investment(OFDI)flows within the context of China’s economy during the period 2011 to ... This paper investigates the impact of provincial innovation-driven efficiency on the expansion of regional Outward Foreign Direct Investment(OFDI)flows within the context of China’s economy during the period 2011 to 2020 by measuring the innovation-driven efficiency and business environment index using the DEA-Malmquist index and the combined CRITIC weighting method from the new perspective of business environment improvement.The findings reveal that:(a)There is an inverted U-shaped relationship between provincial innovation-driven efficiency and regional OFDI flows.This increase in innovation-driven efficiency can promote OFDI expansion of the region by improving its business environment.(b)The improvement of the business environments plays a significant intermediary and synergistic role in OFDI expansion driven by improved innovation efficiency.(c)The study of regional heterogeneity suggests that the central region enjoys the longest window period in terms of innovation-driven OFDI expansion,followed by the eastern region while the western region has the shortest window period.The improvement of the business environment in the western region is more effective in driving regional OFDI expansion.This conclusion remained true after the robustness test.In conclusion,this paper offers a few policy recommendations that can help Chinese capital of various kinds go global more effectively. 展开更多
关键词 innovation as a driver innovation efficiency OFDI expansion business environment
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Cyber Security within Smart Cities:A Comprehensive Study and a Novel Intrusion Detection-Based Approach
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作者 Mehdi Houichi Faouzi Jaidi Adel Bouhoula 《Computers, Materials & Continua》 SCIE EI 2024年第10期393-441,共49页
The expansion of smart cities,facilitated by digital communications,has resulted in an enhancement of the quality of life and satisfaction among residents.The Internet of Things(IoT)continually generates vast amounts ... The expansion of smart cities,facilitated by digital communications,has resulted in an enhancement of the quality of life and satisfaction among residents.The Internet of Things(IoT)continually generates vast amounts of data,which is subsequently analyzed to offer services to residents.The growth and development of IoT have given rise to a new paradigm.A smart city possesses the ability to consistently monitor and utilize the physical environment,providing intelligent services such as energy,transportation,healthcare,and entertainment for both residents and visitors.Research on the security and privacy of smart cities is increasingly prevalent.These studies highlight the cybersecurity risks and the challenges faced by smart city infrastructure in handling and managing personal data.To effectively uphold individuals’security and privacy,developers of smart cities must earn the trust of the public.In this article,we delve into the realms of privacy and security within smart city applications.Our comprehensive study commences by introducing architecture and various applications tailored to smart cities.Then,concerns surrounding security and privacy within these applications are thoroughly explored subsequently.Following that,we delve into several research endeavors dedicated to addressing security and privacy issues within smart city applications.Finally,we emphasize our methodology and present a case study illustrating privacy and security in smart city contexts.Our proposal consists of defining an Artificial Intelligence(AI)based framework that allows:Thoroughly documenting penetration attempts and cyberattacks;promptly detecting any deviations from security standards;monitoring malicious behaviors and accurately tracing their sources;and establishing strong controls to effectively repel and prevent such threats.Experimental results using the Edge-IIoTset(Edge Industrial Internet of Things Security Evaluation Test)dataset demonstrated good accuracy.They were compared to related state-of-theart works,which highlight the relevance of our proposal. 展开更多
关键词 Smart cities digital communications CYBERSECURITY PRIVACY intrusion detection
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Improving innovation and entrepreneurship education in higher institutions: the impact of "Mass Entrepreneurship and Innovation" education on undergraduates' entrepreneurial intentions 被引量:1
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作者 ShaoYing Lu Sun Ye +1 位作者 XiaoShu Xu Yuwei Zhao 《教育技术与创新》 2024年第1期10-26,共17页
The exploration of the way"mass entrepreneurship and innovation"(MEI)education influences students'aspirations to become entrepreneurs has grown into an important area of analysis in studies related to h... The exploration of the way"mass entrepreneurship and innovation"(MEI)education influences students'aspirations to become entrepreneurs has grown into an important area of analysis in studies related to higher education.This research intends to examine the consequences of MEI education on students'tendency towards entrepreneurship,and to put forward methods for augmenting the teaching of innovation and entrepreneurship in private higher educational establishments.To achieve this objective,questionnaires and semi-structured interviews were employed in the study,which involved a total of 197 students and five education experts.The statistical analysis of the questionnaire data revealed that MEI education was positively related to students'entrepreneurial intentions,and that both entrepreneurial experience and family entrepreneurial background played moderating roles in this relationship.The interview findings indicated that private universities could enhance educational reforms by designing talent training programs,developing diversified curricula,and developing more professional entrepreneurial platforms to encourage students'entrepreneurial intentions.This study offers fresh insights for improving and perfecting the mechanism of innovation and entrepreneurship education in private universities. 展开更多
关键词 Private universities Mass Entrepreneurship and innovation MEI education entrepreneurial intention
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How does network intermediary affect collaborative innovation?Evidence from Chinese listed companies
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作者 Zhiwei Zhang Wenhao Zhou 《Journal of Data and Information Science》 CSCD 2024年第4期49-70,共22页
Purpose:This study aims to explore how network intermediaries influence collaborative innovation performance within inter-organizational technological collaboration networks.Design/methodology/approach:This study empl... Purpose:This study aims to explore how network intermediaries influence collaborative innovation performance within inter-organizational technological collaboration networks.Design/methodology/approach:This study employs a mixed-method approach,combining quantitative social network analysis with regression techniques to investigate the role of network intermediaries in collaborative innovation performance.Using a patent dataset of Chinese industrial enterprises,the research constructs the collaboration networks and analyzes their structural positions,particularly focusing on their role as intermediaries,characterized by betweenness centrality.Negative binomial regression analysis is employed to assess how these network characteristics shape innovation outcomes.Findings:The study reveals that firms in intermediary positions enhance collaborative innovation performance,but this effect is nuanced.A key finding is that network clustering negatively moderates the intermediary-innovation relationship.Highly clustered networks,while fostering local collaboration,may limit the innovation potential of intermediaries.On the other hand,relationship strength,measured by collaboration intensity and trust among firms,positively moderates the intermediary-innovation link.Research limitations:This study has several limitations that present opportunities for further research.The reliance on quantitative social network analysis may overlook the complexity of intermediaries’roles,and future studies could benefit from incorporating qualitative methods to better understand cultural and institutional factors.Additionally,cross-country comparisons are needed to assess the consistency of these dynamics in different contexts.Practical implications:The study offers practical insights for firms and policymakers.Organizations should strategically position themselves as network intermediaries to access diverse information and resources,thereby improving innovation performance.Building strong trust helps using network intermediary advantages.For firms in highly clustered networks,it is important to seek external partners to avoid limiting their exposure to new ideas and technologies.This research emphasizes the need to balance network diversity with relationship strength for sustained innovation.Originality/value:This research contributes to the literature by offering new insights into the role of network intermediaries,presenting a comprehensive framework for understanding the interaction between network dynamics and firm innovation. 展开更多
关键词 Network intermediary Collaborative innovation Social network Relationship strength
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Enhanced Cooling Efficiency of Urban Trees on Hotter Summer Days in 70 Cities of China
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作者 Limei YANG Jun GE +4 位作者 Yipeng CAO Yu LIU Xing LUO Shiyao WANG Weidong GUO 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第11期2259-2275,共17页
Increasing the urban tree cover percentage(TCP) is widely recognized as an efficient way to mitigate the urban heat island effect. The cooling efficiency of urban trees can be either enhanced or attenuated on hotter d... Increasing the urban tree cover percentage(TCP) is widely recognized as an efficient way to mitigate the urban heat island effect. The cooling efficiency of urban trees can be either enhanced or attenuated on hotter days, depending on the physiological response of urban trees to rising ambient temperature. However, the response of urban trees' cooling efficiency to rising urban temperature remains poorly quantified for China's cities. In this study, we quantify the response of urban trees' cooling efficiency to rising urban temperature at noontime [~1330 LT(local time), LT=UTC+8] in 17summers(June, July, and August) from 2003–19 in 70 economically developed cities of China based on satellite observations. The results show that urban trees have stronger cooling efficiency with increasing temperature, suggesting additional cooling benefits provided by urban trees on hotter days. The enhanced cooling efficiency values of urban trees range from 0.002 to 0.055℃ %-1 per 1℃ increase in temperature across the selected cities, with larger values for the lowTCP-level cities. The response is also regulated by background temperature and precipitation, as the additional cooling benefit tends to be larger in warmer and wetter cities at the same TCP level. The positive response of urban trees' cooling efficiency to rising urban temperature is explained mainly by the stronger evapotranspiration of urban trees on hotter days.These results have important implications for alleviating urban heat risk by utilizing urban trees, particularly considering that extreme hot days are becoming more frequent in cities under global warming. 展开更多
关键词 urban trees cooling efficiency China's cities EVAPOTRANSPIRATION SUMMER hot days
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The Future of Environmental Engineering Technology:A Disruptive Innovation Perspective
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作者 Hui Huang Junjie Lu +1 位作者 Lili Jin Hongqiang Ren 《Engineering》 SCIE EI CAS CSCD 2024年第10期153-160,共8页
Scientific and technological revolutions and industrial transformations have accelerated the rate of innovation in environmental engineering technologies.However,few researchers have evaluated the current status and f... Scientific and technological revolutions and industrial transformations have accelerated the rate of innovation in environmental engineering technologies.However,few researchers have evaluated the current status and future trends of technologies.This paper summarizes the current research status in eight major subfields of environmental engineering—water treatment,air pollution control,soil/solid waste management,environmental biotechnology,environmental engineering equipment,emerging contaminants,synergistic reduction of pollution and carbon emissions,and environmental risk and intelligent management—based on bibliometric analysis and future trends in greenization,low carbonization,and intelligentization.Disruptive technologies are further identified based on discontinuous transformation,and ten such technologies are proposed,covering general and specific fields,technical links,and value sources.Additionally,the background and key innovations in disruptive technologies are elucidated in detail.This study not only provides a scientific basis for strategic decision-making,planning,and implementation in the environmental engineering field but also offers methodological guidance for the research and determination of breakthrough technologies in other areas. 展开更多
关键词 Environmental engineering technology Disruptive innovation Bibliometric analysis Discontinuous transformation
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Innovation and Firm Co-ownership Network in China’s Electric Vehicle Industry
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作者 JIN Zerun ZHU Shengjun 《Chinese Geographical Science》 SCIE CSCD 2024年第2期195-209,共15页
Firms are embedded in complex networks,where diverse ideas combine and generate new ideas.Shareholders of firms are of-ten seen as critical external resources that have significant influence on firm innovation.The cur... Firms are embedded in complex networks,where diverse ideas combine and generate new ideas.Shareholders of firms are of-ten seen as critical external resources that have significant influence on firm innovation.The current literature tends to focus on the rela-tionship between firms and their shareholders,while paying less attention to the connections between firms with the same shareholders.This article identifies two types of network spillover effects,intra-city network effect and inter-city network effect,by visualizing the co-ownership networks in China’s electric vehicle(EV)industry.We find that firms with the same shareholders,which are defined as co-owned EV firms,are more innovative than non-co-owned ones.Furthermore,there are two dominant types of firm co-ownership ties formed by corporate and financial institution shareholders.While corporate shareholders help exploiting local tacit knowledge,financial institutions are more active in bridging inter-city connections.The conclusion is confirmed at both firm and city levels.This paper theor-izes the firm co-ownership network as a new form of institutional proximity and tested the result empirically.For policy consideration,we have emphasized the importance of building formal or informal inter-firm network,and the government should further enhance the knowledge flow channel by institutional construction. 展开更多
关键词 firm co-ownership intra-city network inter-city network technological innovation electric vehicle China
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Do companies influenced by smart cities pay more attention to green governance?Mechanism and optimal spatial correlation
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作者 Xiaoxu Guo Rao Zhang Yue Zhang 《Chinese Journal of Population,Resources and Environment》 2024年第1期48-57,共10页
Smart cities are a way for China to construct an innovative and environmentally conscious nation.The paper examines the impact of smart cities on corporate green governance and provides a theoretical foundation for fo... Smart cities are a way for China to construct an innovative and environmentally conscious nation.The paper examines the impact of smart cities on corporate green governance and provides a theoretical foundation for formulating and executing smart city policy in China.Based on panel data from Chinese A-share listed companies in Shanghai and Shenzhen from 2008 to 2020,this study constructs a multiperiod double-difference model to examine the influence of smart cities on corporate green governance.Additionally,it uses a spatial double-difference model to investigate the spatial spillover effect of smart cities on neighboring areas.The findings indicate that smart cities effectively enhance corporate green governance.Analyzing the influencing mechanisms reveals that resource allocation efficiency,technological innovation,management environmental awareness,and regional environmental enforcement efforts act as mediators.Furthermore,the study reveals that the impact of smart cities on promoting corporate green governance is more pronounced in regions with lower levels of marketization and resource-based cities.Moreover,the research explores the spatial spillover effects of smart cities,with an effective radius of approximately 350 km.The optimal spatial correlation zone for green governance of businesses in neighboring areas in relation to smart cities is within a range of 250-350 km.This is manifested by the significant promotion of green governance in neighboring area businesses facilitated by smart cities. 展开更多
关键词 Smart cities Corporate green governance Mediating effects Spatial associations
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The Mediating Effect of Digital Transformation on the Link Between Executive Overconfidence and Corporate Green Innovation
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作者 Zhu Yong Zhu Beibei 《Contemporary Social Sciences》 2024年第5期51-69,共19页
Green technological innovation is crucial for the manufacturing industry’s green transformation and sustainable development.This study examines the impact of executive overconfidence on corporate green innovation,foc... Green technological innovation is crucial for the manufacturing industry’s green transformation and sustainable development.This study examines the impact of executive overconfidence on corporate green innovation,focusing on the internal drivers of corporate innovation and using a sample of Shanghai and Shenzhen A-share listed manufacturing companies from 2013 to 2020.We further examine the mediating role of digital transformation and the moderating role of external attention.The findings indicate that executive overconfidence promotes corporate green technological innovation.Overconfident executives enhance green innovation by accelerating digital transformation.Moreover,external attention from analysts and media positively moderates the relationship between executive overconfidence and corporate green innovation.Heterogeneity analysis reveals that the positive impact of executive overconfidence on green innovation is more significant in non-state-owned enterprises,high-tech firms,and enterprises with lower pollution levels. 展开更多
关键词 executive overconfidence digital transformation green innovation
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Factors Influencing the Spatial Variability of Air Temperature Urban Heat Island Intensity in Chinese Cities
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作者 Heng LYU Wei WANG +3 位作者 Keer ZHANG Chang CAO Wei XIAO Xuhui LEE 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第5期817-829,共13页
Few studies have investigated the spatial patterns of the air temperature urban heat island(AUHI)and its controlling factors.In this study,the data generated by an urban climate model were used to investigate the spat... Few studies have investigated the spatial patterns of the air temperature urban heat island(AUHI)and its controlling factors.In this study,the data generated by an urban climate model were used to investigate the spatial variations of the AUHI across China and the underlying climate and ecological drivers.A total of 355 urban clusters were used.We performed an attribution analysis of the AUHI to elucidate the mechanisms underlying its formation.The results show that the midday AUHI is negatively correlated with climate wetness(humid:0.34 K;semi-humid:0.50 K;semi-arid:0.73 K).The annual mean midnight AUHI does not show discernible spatial patterns,but is generally stronger than the midday AUHI.The urban–rural difference in convection efficiency is the largest contributor to the midday AUHI in the humid(0.32±0.09 K)and the semi-arid(0.36±0.11 K)climate zones.The release of anthropogenic heat from urban land is the dominant contributor to the midnight AUHI in all three climate zones.The rural vegetation density is the most important driver of the daytime and nighttime AUHI spatial variations.A spatial covariance analysis revealed that this vegetation influence is manifested mainly through its regulation of heat storage in rural land. 展开更多
关键词 air temperature urban heat island spatial variations biophysical drivers Chinese cities climate model
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Surgeon Perspectives on Anastomotic Leaks and FluidAI’s StreamTM Platform: Integrating Qualitative Insights for Technological Innovation
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作者 Olivia Rennie Manaswi Sharma Nour Helwa 《Surgical Science》 2024年第8期492-500,共9页
Purpose: This article investigates the critical importance of integrating surgeons’ direct input into the development of innovative technologies that address gaps in surgical care, including those aimed at reducing a... Purpose: This article investigates the critical importance of integrating surgeons’ direct input into the development of innovative technologies that address gaps in surgical care, including those aimed at reducing anastomotic leaks (AL), a major complication in gastrointestinal surgery. While traditional quantitative research methods are prevalent, they often overlook the invaluable insights of the surgeons who manage these complications firsthand. Subjects and Methods: This study employs a qualitative approach, utilizing semi-structured interviews with 40 surgeons from various specialties, including general, bariatric, colorectal, trauma, hepato-biliary, and thoracic surgery. The interviews were designed to probe the needs of surgeons, challenges currently faced, and gaps in clinical practice, research, and technology for detection and/or management of AL. The data were analyzed using thematic analysis, which revealed significant gaps in current technologies for early detection and prevention of leaks. Results: Surgeons expressed strong interest in FluidAI’s Stream™ Platform, a non-invasive medical device designed to monitor postoperative drainage fluid in real-time, providing continuous data on AL risk. The ability of this platform to offer early prediction through pH and electrical conductivity analysis was particularly appealing to participants, who emphasized the importance of timely interventions in improving patient outcomes. The study’s findings highlight not only the clinical challenges but also the emotional toll that AL takes on surgeons, underlining the need for innovations that are both data-driven and humanistic. Conclusion: By centering surgeons’ perspectives, this research advocates for a human-centered approach to technological advancement, ensuring that new tools are both clinically effective and aligned with the real-world needs of surgical practitioners. 展开更多
关键词 Anastomotic Leaks Surgeon Perspectives Postoperative Complications Qualitative Inquiry Technological innovation
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Fast-to-Clinic, Fast-to-Market in Biotech Innovation: Optimizing Chemistry Manufacturing & Controls (CMC) Excellence for Clinical and Commercial Success
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作者 Kishore Kumar Hotha 《Advances in Chemical Engineering and Science》 CAS 2024年第3期155-171,共17页
In the emerging world of biotech innovation, the fast-to-clinic/market strategy has emerged as a critical “mantra” for biotech, investors, and CDMOs. This approach addresses the escalating costs and complexities of ... In the emerging world of biotech innovation, the fast-to-clinic/market strategy has emerged as a critical “mantra” for biotech, investors, and CDMOs. This approach addresses the escalating costs and complexities of research and development by streamlining the path from concept to clinical trials and, ultimately, to market. The article delves into the intricacies of implementing a fast-to-clinic/market strategy, underlining the empowering role of strategic decision-making in preclinical and commercial stages. The plan advocates for a phase-appropriate approach, where the development decision is tailored to each phase of the product’s lifecycle. This ensures that resources are allocated efficiently, risks are managed effectively, and the product can move through the development pipeline accelerated without compromising quality or regulatory compliance. The article also discusses the role of CDMOs in facilitating rapid product development and the essential factors biotech companies must consider when selecting a partner for outsourcing. These factors include the CDMO’s expertise in navigating regulatory landscapes, technological capabilities, and ability to scale processes efficiently. Moreover, the article stresses the importance of agility and flexibility in the fast-to-clinic/market approach. Biotech companies are encouraged to adopt adaptable strategies that respond to the fast-evolving regulatory and market landscapes. 展开更多
关键词 Fast to Clinic innovation CDMO CMC PRECLINICAL FDA IND NDA ANDA BIOTECH
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Cultivation Path of Nursing Undergraduates’Scientific Research and Innovation Ability
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作者 Guanying Yang Yuan Zhao 《Journal of Biosciences and Medicines》 2024年第5期202-212,共11页
Objective: The cultivation of the innovation ability and scientific research is one of the nursing learning objectives for undergraduate students. To explore the method and effect of training system of scientific rese... Objective: The cultivation of the innovation ability and scientific research is one of the nursing learning objectives for undergraduate students. To explore the method and effect of training system of scientific research innovation ability of nursing undergraduates based on “3332”. Methods: Three course learning modules are constructed: stage-based course learning module, systematic project practice training module and comprehensive practice training module. A practical training platform for scientific research innovation projects is built, and undergraduate scientific research innovation ability training is carried out from both in-class and out-of-class lines. Results: Since 2017, the students have obtained 7 national innovation and entrepreneurship training programs, 52 university-level undergraduate scientific research projects, published more than 10 academic papers, and obtained 2 patent authorization. Conclusions: The training system of scientific research innovation ability of nursing undergraduates based on “3332” is conducive to the development of scientific research innovation ability of nursing students, and to cultivate nursing talents who can adapt to the development of the new era and have better post competence. 展开更多
关键词 Nursing Undergraduates Scientific Research innovation Ability Learning Module Cultivation Path
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Coordination Mechanism and Empirical Research on Marine Science Technology Innovation and Marine Eco-civilization:A Case Study of Coastal Areas of China
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作者 CHEN Xiaolong LIANG Chenlu DI Qianbin 《Chinese Geographical Science》 SCIE CSCD 2024年第3期468-486,共19页
Marine science technology innovation provides power and guarantees for marine eco-civilization construction,which provides direction and material support for marine science technology innovation.Therefore,the coordina... Marine science technology innovation provides power and guarantees for marine eco-civilization construction,which provides direction and material support for marine science technology innovation.Therefore,the coordinated development of the two is of great significance to the marine economy sustainable development in China’s coastal areas.On the basis of clarifying the connotations of marine science technology innovation and marine eco-civilization in China’s coastal areas from 2006 to 2019,the mechanism for their coordinated development was analysed.A comprehensive indicator system based on the connotation of the two was constructed,and the coordinated development relationship was empirically tested using the coupled coordination model and the panel vector autoregressive(PVAR)model.The results show that:1)the level of China’s coastal marine science technology innovation continues to improve,gradually forming the core of the development of marine science technology innovation in the north,east and south of Shandong,Shanghai and Guangdong;the level of marine eco-civilization development fluctuating upward trend,showing obvious spatial differentiation characteristics.2)The degree of coordination of marine science technology innovation and marine eco-civilization is growing over time.There is no causal relationship between marine science technology innovation and marine eco-civilization in the northern marine economic circle,but there is a two-way causal relationship between the two in the eastern and southern marine economic circles.3)Marine eco-civilization shows a significant positive and continuous impact on marine science technology innovation,and marine science technology innovation shows a long-term,continuous,fluctuating,and lagging impact on marine eco-civilization.The overall role of marine eco-civilization on marine science technology innovation is dominant,and there are significant differences in the impact effects of the two major marine economic circles. 展开更多
关键词 marine science technology innovation marine eco-civilization coordinated development coastal areas of China
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How to promote cooperative innovation in environmentally friendly technology:a case of agricultural biotechnology in China
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作者 Hongkun Ma Xian Mi +5 位作者 Yi Zheng Ning Lv Shan Zhang Chunting Hu Xiaowei Wu Yuan Cao 《Chinese Journal of Population,Resources and Environment》 2024年第2期127-135,共9页
This study explored the factors influencing cooperative innovation in environmentally friendly agricultural biotechnology in China.First,we constructed an evolutionary game model comprising the factors of net income o... This study explored the factors influencing cooperative innovation in environmentally friendly agricultural biotechnology in China.First,we constructed an evolutionary game model comprising the factors of net income of cooperative innovation,net income of independent innovation,market constraints,and government subsidies.Using MATLAB simulation,we assigned different values to the aforementioned variables to explore the evolutionary trend of innovators’willingness to cooperate.Results showed that when the values of net income of cooperative innovation,net income of independent innovation,market constraints,and government subsidies exceeded the threshold,innovators’willingness to cooperate was significantly enhanced.Furthermore,the proportion of innovators who cooperated with others gradually increased to 100%;otherwise,it gradually decreased to 0%.Comparing the simulation curve with the real evolution curve of cooperative innovation in agricultural biotechnology in China,we found that the gradual decline in the willingness to cooperate could be due to insufficient subsidies for cooperative innovation,low income from cooperative innovation,weak profitability of innovators,and weak market constraints. 展开更多
关键词 Cooperative innovation Evolutionary game MATLAB Simulation Agricultural biotechnology Environmentally friendly technology
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