Background: Although a common dermatosis, idiopathic poikiloderma of the face and neck has not been studied in depth for decades. Objectives: To reassess the clinical and epidemiological characteristics of poikiloderm...Background: Although a common dermatosis, idiopathic poikiloderma of the face and neck has not been studied in depth for decades. Objectives: To reassess the clinical and epidemiological characteristics of poikiloderma of Civatte (PC). Ma terial and methods: Fifty consecutive patients with PC. Evaluation included hist ory taking and physical examination. Epidemiological and clinical parameters wer e recorded and analysed. The literature from 1923 until today, was reviewed thor oughly. Results: The frequency of PC among dermatologic patients was estimated t o be 1.4%. There were 34 females (68%) and 16 males in the present study. The mean age at diagnosis was 47.8 years for females and 61.7 years for males. The m ajority (88%) had skin phototype II or III. Among females, 26 were at their per imenopausal stage, including three cases of iatrogenic menopause. Four patients reported that other blood-related family members also had PC. The v and the sid es of the neck and the upper chest were most often affected in a symmetric distr ibution. The face (preauricular and parotid region) was involved in 19 patients (38%). The erythematotelangiectatic clinical type predominated (58%), followed by the mixed (22%) and the pigmented type (20%). Almost half of the patients (46%) were symptomatic (itching, burning and ’flushing’). The mean duration fro m onset to diagnosis was 6.2 years according to the patients’report. The course was usually slowly progressive (82%) and irreversible. Conclusions: PC shows c haracteristic features, supporting the theory that it represents a distinct enti ty. It is rather common in Greece. Although menopausalwomen predominated in our cohort, men were not uncommonly affected and were diagnosed at an older age. Bas ed on the predominating clinical feature, PC can be classified into three clinic al forms. Symmetry and sparing of the anatomically shaded areas of the neck are highly characteristic for PC. Face involvement was not as common and as severe a s it had been considered in the past. Recognition of clinical type is important for the selection of the most appropriate treatment, which, despite the advent o f novel modalities, remains problematic.展开更多
文摘Background: Although a common dermatosis, idiopathic poikiloderma of the face and neck has not been studied in depth for decades. Objectives: To reassess the clinical and epidemiological characteristics of poikiloderma of Civatte (PC). Ma terial and methods: Fifty consecutive patients with PC. Evaluation included hist ory taking and physical examination. Epidemiological and clinical parameters wer e recorded and analysed. The literature from 1923 until today, was reviewed thor oughly. Results: The frequency of PC among dermatologic patients was estimated t o be 1.4%. There were 34 females (68%) and 16 males in the present study. The mean age at diagnosis was 47.8 years for females and 61.7 years for males. The m ajority (88%) had skin phototype II or III. Among females, 26 were at their per imenopausal stage, including three cases of iatrogenic menopause. Four patients reported that other blood-related family members also had PC. The v and the sid es of the neck and the upper chest were most often affected in a symmetric distr ibution. The face (preauricular and parotid region) was involved in 19 patients (38%). The erythematotelangiectatic clinical type predominated (58%), followed by the mixed (22%) and the pigmented type (20%). Almost half of the patients (46%) were symptomatic (itching, burning and ’flushing’). The mean duration fro m onset to diagnosis was 6.2 years according to the patients’report. The course was usually slowly progressive (82%) and irreversible. Conclusions: PC shows c haracteristic features, supporting the theory that it represents a distinct enti ty. It is rather common in Greece. Although menopausalwomen predominated in our cohort, men were not uncommonly affected and were diagnosed at an older age. Bas ed on the predominating clinical feature, PC can be classified into three clinic al forms. Symmetry and sparing of the anatomically shaded areas of the neck are highly characteristic for PC. Face involvement was not as common and as severe a s it had been considered in the past. Recognition of clinical type is important for the selection of the most appropriate treatment, which, despite the advent o f novel modalities, remains problematic.
