Six cycloartanes were isolated from ethanol extract of marine green alga Cladophora fascicularis by column chromatography. Procedure of isolation and description of these compounds are given in this paper. The structu...Six cycloartanes were isolated from ethanol extract of marine green alga Cladophora fascicularis by column chromatography. Procedure of isolation and description of these compounds are given in this paper. The structures were elucidated as （1）. 24-hydroperoxycycloart-25- en-3β-ol; （2）. cycloart-25-en-3β 24-diol; （3）. 25-hydroperoxycycloart-23-en-3β-ol; （4）. cycloart-23-en-3β, 25-diol; （5）. cycloart-23, 25-dien-3β-ol; and （6）. cycloart-24-en-3β-ol by spectroscopic （MS, 1D and 2D NMR） data analysis. Cycloartane derivatives are widely distributed the alga. All these compounds that have been isolated alga for the first time. in terrestrial plants, but only few were obtained in from terrestrial plants, were found in the marine alga for the first time.展开更多
基金Supported by the National High-Tech R&D Program (863 Program) (Nos. 2001AA620403, 2003AA620403 and 2002AA217081) the State Major Basic Research Development Program of China (973 Program, No. 2002CB41240)+1 种基金 the Major Program of CAS (No. KJCX315-215) NSFC(Nos. 40176038, 30171106, and 30530080) and the International Cooperation Projects of BMBF-CNCBD
文摘Six cycloartanes were isolated from ethanol extract of marine green alga Cladophora fascicularis by column chromatography. Procedure of isolation and description of these compounds are given in this paper. The structures were elucidated as （1）. 24-hydroperoxycycloart-25- en-3β-ol; （2）. cycloart-25-en-3β 24-diol; （3）. 25-hydroperoxycycloart-23-en-3β-ol; （4）. cycloart-23-en-3β, 25-diol; （5）. cycloart-23, 25-dien-3β-ol; and （6）. cycloart-24-en-3β-ol by spectroscopic （MS, 1D and 2D NMR） data analysis. Cycloartane derivatives are widely distributed the alga. All these compounds that have been isolated alga for the first time. in terrestrial plants, but only few were obtained in from terrestrial plants, were found in the marine alga for the first time.
