Low-level laser therapy (LLLT) or cold laser has been used in medicine for several decades. However, the method utilizes a direct contact of the light beam with a patient. Further research resulted in development of a...Low-level laser therapy (LLLT) or cold laser has been used in medicine for several decades. However, the method utilizes a direct contact of the light beam with a patient. Further research resulted in development of another method that enables remote transmission of the pharmacological properties of a medicament into a human body with the application of low-level laser radiation as the light source. 18 patients with different viral diseases were treated with the antiviral drugs placed into the field formed by the unexplained properties of low-level laser radiation of the “device for transfer of the pharmacological properties of a drug into the patient’s body”. This resulted in improvement of the patient’s condition, the absence of side effects and adverse reactions when using drugs in the proposed device and shortened therapy period for patients with chronic hepatitis C infection and Covid-19 patients. The long-term follow-up of the patients with chronic hepatitis B infection showed that hepatitis B virus remained at low replication levels under the influence of the therapy, which made it possible to avoid such formidable complications of the disease as cirrhosis of the liver and liver cancer.展开更多
目的评估在静配中心应用密闭式药物配制和转运系统(closed-system drug transfer device,CSTD)对细胞毒性药物在工作环境中污染残留量的影响。方法利用环磷酰胺为示例药物,通过WIPE采样法和高效液相色谱法定量检测复旦大学附属肿瘤医院...目的评估在静配中心应用密闭式药物配制和转运系统(closed-system drug transfer device,CSTD)对细胞毒性药物在工作环境中污染残留量的影响。方法利用环磷酰胺为示例药物,通过WIPE采样法和高效液相色谱法定量检测复旦大学附属肿瘤医院静配中心配制舱内环境中环磷酰胺残留量。在常规配制方法配药的一个工作日配药结束时清理前、清理后以及连续应用3周CSTD进行配药工作后,分别进行3批采样。采样位置包括3个生物安全柜(BSC)操作台面、转运小推车、出舱台等19个位置。比较3批样本中环磷酰胺的残留量。结果常规配药清理去污前各监测点中位值为1.30(IRQ:0.24,2.60)ng/cm^2,去污后中位值为0.22(IRQ:0.08,0.53)ng/cm^2,前后比较差异有统计学意义(P<0.001)。CSTD系统配药后,各监测点中位值为0.06(0.02,0.88)ng/cm^2,明显低于常规方法去污前(P<0.001),也低于常规方法去污后,但差异无统计学意义(P=0.299)。结论应用CSTD可有效减少细胞毒性药物在配制转运过程中的渗漏污染,从而显著减少相关医务人员的毒性药物职业暴露。展开更多
文摘Low-level laser therapy (LLLT) or cold laser has been used in medicine for several decades. However, the method utilizes a direct contact of the light beam with a patient. Further research resulted in development of another method that enables remote transmission of the pharmacological properties of a medicament into a human body with the application of low-level laser radiation as the light source. 18 patients with different viral diseases were treated with the antiviral drugs placed into the field formed by the unexplained properties of low-level laser radiation of the “device for transfer of the pharmacological properties of a drug into the patient’s body”. This resulted in improvement of the patient’s condition, the absence of side effects and adverse reactions when using drugs in the proposed device and shortened therapy period for patients with chronic hepatitis C infection and Covid-19 patients. The long-term follow-up of the patients with chronic hepatitis B infection showed that hepatitis B virus remained at low replication levels under the influence of the therapy, which made it possible to avoid such formidable complications of the disease as cirrhosis of the liver and liver cancer.
文摘目的评估在静配中心应用密闭式药物配制和转运系统(closed-system drug transfer device,CSTD)对细胞毒性药物在工作环境中污染残留量的影响。方法利用环磷酰胺为示例药物,通过WIPE采样法和高效液相色谱法定量检测复旦大学附属肿瘤医院静配中心配制舱内环境中环磷酰胺残留量。在常规配制方法配药的一个工作日配药结束时清理前、清理后以及连续应用3周CSTD进行配药工作后,分别进行3批采样。采样位置包括3个生物安全柜(BSC)操作台面、转运小推车、出舱台等19个位置。比较3批样本中环磷酰胺的残留量。结果常规配药清理去污前各监测点中位值为1.30(IRQ:0.24,2.60)ng/cm^2,去污后中位值为0.22(IRQ:0.08,0.53)ng/cm^2,前后比较差异有统计学意义(P<0.001)。CSTD系统配药后,各监测点中位值为0.06(0.02,0.88)ng/cm^2,明显低于常规方法去污前(P<0.001),也低于常规方法去污后,但差异无统计学意义(P=0.299)。结论应用CSTD可有效减少细胞毒性药物在配制转运过程中的渗漏污染,从而显著减少相关医务人员的毒性药物职业暴露。
