To As one of the most common cardiovascular diseases,coronary heart disease has a high morbidity and mortality.In recent years,non-drug therapy has been put on equal importance with drug therapy due to its simple oper...To As one of the most common cardiovascular diseases,coronary heart disease has a high morbidity and mortality.In recent years,non-drug therapy has been put on equal importance with drug therapy due to its simple operation and fast onset.Cognitive behavioral therapy,as a kind of non-drug therapy,has been widely used to improve the physical and mental symptoms of patients with coronary heart disease.This article reviews the origin,concept,theoretical basis,characteristics,technology,and current research status of cognitive behavioral therapy in patients with coronary heart disease,in order to provide a reference for the clinical development of cognitive behavioral therapy.展开更多
Background Aortic dissection(AD)is one of the serious diseases that threaten human life. Endovascular aortic ancurysm repair(EVAR),as a first-line treatment of type B AD,has the advantages of short operation time,litt...Background Aortic dissection(AD)is one of the serious diseases that threaten human life. Endovascular aortic ancurysm repair(EVAR),as a first-line treatment of type B AD,has the advantages of short operation time,little trauma,and rapid recovery. Previous studies have paid more attention to the clinical prognosis and imaging changes after endovascular repair of AD,with few focus on the quality of life after operation. The prevalence of coronary heart disease(CHD)has dramatically risen during the past few decades. Percutaneous coronary intervention(PCI)is considered one of the primary approaches for CHD treatment. Anxiety and depression are commonly associated with coronary heart disease(CHD). Psychological problems may be related with occurrence of unhealthy lifestyles and non-adherence to treatment. This study was to explore psychological characteristics and the quality of life and their influencing factors after interventional therapy of AD and CHD.Methods Respectively 100 AD and 100 CHD patients undergoing interventional therapy were investigated with SF-36,self-rating anxiety scale(SAS),self-rating depression scale(SDS)and social support scale. The values of SF-36,SAS,SDS between the AD and CHD group were analyzed. The influencing factors of quality of life were evaluated. Results There was no significant difference in SF-36 score between AD patients after endovascular repair and CHD patients after percutaneous coronary intervention. However,the scores in the dimensions of role-physical(54.00±41.54 vs. 65.25±34.43,P=0.038)and social functioning(74.00±20.69 vs.81.00±20.35,P=0.020)were lower in AD patients than in CHD patients. Multiple linear regression analysis showed that age,occupational status,postoperative time,anxiety,depression,and social support were the influencing factors of life quality in aortic dissection patients. Conclusion Compared with CHD patients receiving percutaneous coronary intervention,quality of life in AD patients after endovascular repair should be paid attention to. It is necessary that a multidisciplinary team including psychological medical staff should be established to manage AD patients.展开更多
Objective:To assess the efficacy and safety of Guanxin Danshen Dripping Pills(GXDS)in the treatment of depression or anxiety in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Me...Objective:To assess the efficacy and safety of Guanxin Danshen Dripping Pills(GXDS)in the treatment of depression or anxiety in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods:From September 2017 to June 2019,200 CHD patients after PCI with depression and anxiety were included and randomly divided into GXDS(100 cases)and placebo control groups(100 cases)by block randomization and a random number table.Patients in the GXDS and control groups were given GXDS and placebo,respectively,0.4 g each time,3 times daily for 12 weeks.The primary outcomes were scores of Patient Health Questionnaire-9(PHQ-9),Generalized Anxiety Scale(GAD-7)and the Seattle Angina Pectoris Scale(SAQ).The secondary outcomes included 12 Health Survey Summary Form(SF-12)scores and the first onset time and incidence of major adverse cardiovascular events(MACEs).Other indices including blood pressure,blood lipids,microcirculation and inflammatory-related indices,etc.were monitored at baseline,week 4,and week 12.Results:In the full analysis set(200 cases),after treatment,the PHQ-9 and GAD-7 scores in the GXDS group were considerably lower than those in the control group(P<0.05).Compared with the baseline,the total PHQ-9 scores of the experimental and control groups decreased by 3.97 and 1.18,respectively.The corrected mean difference between the two groups was–2.78(95%CI:–3.47,–2.10;P<0.001).The total GAD-7 score in the GXDS group decreased by 3.48%compared with the baseline level,while that of the placebo group decreased by 1.13%.The corrected mean difference between the two groups was–2.35(95%CI:–2.95,–1.76;P<0.001).The degree of improvement in SAQ score,SF-12 score,endothelin and high-sensitive C-reactive protein levels in the GXDS group were substantially superior than those in the placebo group,and the differences between the two groups were statistically significant(P<0.05).Similar results were obtained in the per protocol population analysis of 177 patients.Three cases of MACES were reported in this study(1 in the GXDS group and 2 in the placebo group),and no serious adverse events occurred.Conclusions:GXDS can significantly alleviate depression and anxiety,relieve symptoms of angina,and improve quality of life in patients with CHD after PCI.(Registration No.ChiCTR1800014291)展开更多
文摘To As one of the most common cardiovascular diseases,coronary heart disease has a high morbidity and mortality.In recent years,non-drug therapy has been put on equal importance with drug therapy due to its simple operation and fast onset.Cognitive behavioral therapy,as a kind of non-drug therapy,has been widely used to improve the physical and mental symptoms of patients with coronary heart disease.This article reviews the origin,concept,theoretical basis,characteristics,technology,and current research status of cognitive behavioral therapy in patients with coronary heart disease,in order to provide a reference for the clinical development of cognitive behavioral therapy.
基金supported by Guangdong Medical Research Fund Project(No.A2016140)
文摘Background Aortic dissection(AD)is one of the serious diseases that threaten human life. Endovascular aortic ancurysm repair(EVAR),as a first-line treatment of type B AD,has the advantages of short operation time,little trauma,and rapid recovery. Previous studies have paid more attention to the clinical prognosis and imaging changes after endovascular repair of AD,with few focus on the quality of life after operation. The prevalence of coronary heart disease(CHD)has dramatically risen during the past few decades. Percutaneous coronary intervention(PCI)is considered one of the primary approaches for CHD treatment. Anxiety and depression are commonly associated with coronary heart disease(CHD). Psychological problems may be related with occurrence of unhealthy lifestyles and non-adherence to treatment. This study was to explore psychological characteristics and the quality of life and their influencing factors after interventional therapy of AD and CHD.Methods Respectively 100 AD and 100 CHD patients undergoing interventional therapy were investigated with SF-36,self-rating anxiety scale(SAS),self-rating depression scale(SDS)and social support scale. The values of SF-36,SAS,SDS between the AD and CHD group were analyzed. The influencing factors of quality of life were evaluated. Results There was no significant difference in SF-36 score between AD patients after endovascular repair and CHD patients after percutaneous coronary intervention. However,the scores in the dimensions of role-physical(54.00±41.54 vs. 65.25±34.43,P=0.038)and social functioning(74.00±20.69 vs.81.00±20.35,P=0.020)were lower in AD patients than in CHD patients. Multiple linear regression analysis showed that age,occupational status,postoperative time,anxiety,depression,and social support were the influencing factors of life quality in aortic dissection patients. Conclusion Compared with CHD patients receiving percutaneous coronary intervention,quality of life in AD patients after endovascular repair should be paid attention to. It is necessary that a multidisciplinary team including psychological medical staff should be established to manage AD patients.
文摘Objective:To assess the efficacy and safety of Guanxin Danshen Dripping Pills(GXDS)in the treatment of depression or anxiety in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods:From September 2017 to June 2019,200 CHD patients after PCI with depression and anxiety were included and randomly divided into GXDS(100 cases)and placebo control groups(100 cases)by block randomization and a random number table.Patients in the GXDS and control groups were given GXDS and placebo,respectively,0.4 g each time,3 times daily for 12 weeks.The primary outcomes were scores of Patient Health Questionnaire-9(PHQ-9),Generalized Anxiety Scale(GAD-7)and the Seattle Angina Pectoris Scale(SAQ).The secondary outcomes included 12 Health Survey Summary Form(SF-12)scores and the first onset time and incidence of major adverse cardiovascular events(MACEs).Other indices including blood pressure,blood lipids,microcirculation and inflammatory-related indices,etc.were monitored at baseline,week 4,and week 12.Results:In the full analysis set(200 cases),after treatment,the PHQ-9 and GAD-7 scores in the GXDS group were considerably lower than those in the control group(P<0.05).Compared with the baseline,the total PHQ-9 scores of the experimental and control groups decreased by 3.97 and 1.18,respectively.The corrected mean difference between the two groups was–2.78(95%CI:–3.47,–2.10;P<0.001).The total GAD-7 score in the GXDS group decreased by 3.48%compared with the baseline level,while that of the placebo group decreased by 1.13%.The corrected mean difference between the two groups was–2.35(95%CI:–2.95,–1.76;P<0.001).The degree of improvement in SAQ score,SF-12 score,endothelin and high-sensitive C-reactive protein levels in the GXDS group were substantially superior than those in the placebo group,and the differences between the two groups were statistically significant(P<0.05).Similar results were obtained in the per protocol population analysis of 177 patients.Three cases of MACES were reported in this study(1 in the GXDS group and 2 in the placebo group),and no serious adverse events occurred.Conclusions:GXDS can significantly alleviate depression and anxiety,relieve symptoms of angina,and improve quality of life in patients with CHD after PCI.(Registration No.ChiCTR1800014291)
