Stent-assisted coiling of intracranial carotid ophthalmic segment aneurysm segment aneurysms:Long-term follow-up from a single center

Background:To evaluate the efficacy of stent-assisted coiling(SAC)for the treatment of carotid ophthalmic segment aneurysm segment aneurysms(OSAs)of the internal carotid artery(ICA)through detailed long-term follow-up of a large patient cohort.Methods:We retrospectively analyzed 88 consecutive patients with OSAs between January 2009 and January 2020 at our center.Angiographic results were evaluated using the modified Raymond grading system and clinical outcomes were evaluated using the mRS scale.The primary endpoints were major aneurysm recurrence and poor clinical outcomes for at least 18 months of follow-up.The patients were asked to attend clinical follow-up assessments and possibly undergo DSA or MR via telephone.Results:We enrolled 88 patients with 99 OSAs treated with coiling,of whom 76 were treated with SAC.The coiling procedures were successful in all 88 patients.Overall,complications occurred in 8 patients(9.1%).No procedure-related mortality was observed.67(76.1%)experienced immediate aneurysm occlusion at the end of the procedure.Long-term angiographic follow-up(18 months)was available in 45/88 aneurysms(51%)(average 18.7±5.2 months).Four patients continued their follow-up for 5 years after initial aneurysm treatment.After a clinical follow-up time of 28.7 months(range,12-51 months),85 patients(95.5%)achieved favorable clinical outcomes(mRS scores of 0-2).Conclusions:This study indicates that SAC treatment is a safe and effective therapeutic alternative for ruptured and unruptured OSAs.The procedural risks are low with relatively long-term effectiveness.

Degree of style coiling is associated with corolla-tube length in the nectarless flowers of Roscoea schneideriana

The plant-pollinator‘arms race’model posits that a major driver of the evolution of elongated corollas in flowers is reciprocal selection for‘morphological fit’between pollinator-tongue length and access distance to nectar(usually corolla-tube length).Evidence for the pollinator-mediated selection on tube length and evolution of multiple,correlated floral traits remains inconclusive.To gain possible insights into the strength of stabilizing selection by assessing standing phenotypic variation,we measured a series of functionally important floral traits,including corolla tube length and‘effective’tube depth and degree of style coiling.We then calculated coefficients of variation(CV)for these traits in three field populations of R.schneideriana.Unlike in most long-tubed flowers,the bottom part of the corolla tube is completely occupied by the style,with no room for nectar.The length of this portion of the corolla tube was more variable(higher CV)than the upper part of the corolla tube,suggesting that functional tube depth was under stronger stabilizing selection.The degree of style coiling was negatively related to the corolla-tube length in all three populations of R.schneideriana,suggesting that there may be conflicting selection acting on style length and corolla-tube length,which are otherwise usually tightly correlated.Given the lack of nectar in the flowers of this species,the long corolla tubes and long styles may represent morphological holdovers from ancestors that were pollinated by long-tongued pollinators,as is still seen in related species in the western Himalayas.

Applications of multislice CT angiography in the surgical clipping and endovascular coiling of intracranial aneurysms

Prompt diagnosis and therapy of aneurysms are critical for patients with nontraumatic subarachnoid hemorrhage （SAH）.The aim of our study was to assess the clinical usefulness of multislice computed tomography angiography （CTA） in the surgical and endovascular treatment of intracranial aneurysms.A total of 195 cases with 206 intracranial aneurysms underwent CTA.Fifty （24%） aneurysms underwent surgical clipping while 156 （76%） aneurysms underwent endovascular coiling.In the five missed aneurysms at digital substraction angiography and the nine aneurysms with mass intracerebral hematomas,surgical treatment was successfully performed based on 16-slice CTA alone,and the other 36 aneurysms were clipped on the main basis of the CTA.The intraoperative findings correlated well with the CTA findings and all aneurysms were clipped successfully.Sixteen-slice CTA image information has been shown to determine the choice of aneurysm therapy and assist the surgical and endovascular treatment of intracranial aneurysms.

Intelligent Control on Hot Strip Coiling Temperature

A new intelligent control scheme for hot strip coiling temperature is presented. In this scheme, the prediction mode1 of finishing temperature and the presetting model of main cooling zone are establish based on BP neural network, the feed-forward open-loop control model of main cooling zone is constructed based on T-S fuzzy neural network, a new improved structure of T-S fuzzy neural network is developed, and the feedback close-loop control model of precision cooling zone is obtained based on fuzzy control. The effectiveness of the proposed scheme has been demonstrated by computer simulation with a satisfactory result.

Effect of Coiling Temperature on Ti(C,N) Precipitation and Properties of Batch Annealed DC06EK Enamel Steel

The effects of hot-strip coiling temperature on Ti（C,N） precipitation, texture and hydrogen permeation behavior in DC06 EK enamel steel were investigated by TEM, EBSD test and electrochemical hydrogen permeation experiment. It was found that the Ti（C,N） particles in hot-strip coarsened with increasing coiling temperature, whereas after cold-rolling and annealing, the size difference of Ti（C,N） particles was lessened. The hot-strip coiling temperature has a significant impact on the recrystallized texture in the subsequent cold-rolled and annealed sheet. Hot-strip using high temperature（700 ℃） coiling leads to strong {111} recrystallized texture in annealed sheet, with peak intensity 9.2. On the contrary, in annealed sheets using hot-strip coiling at 650 ℃, their {111} recrystallized textures were weaker, which was also reflected in their rmvalues. Even though the hydrogen diffusion coefficient is slightly lower（7.76×10^（-5） mm^2/s） in annealed sheet using low temperature coiling（600 ℃）, appropriately higher coiling temperature is more suitable for DC06 EK enamel steel combining both good drawability and fish-scale resistance.

The effect of cooling rate and coiling temperature on the microstructure and mechanical properties of a plain carbon steel

The effects of cooling rate and coiling temperature on microstructure and mechanical properties of a plain carbon steel were investigated by combining metallography and tensile experiments. The results indicate that ferrite grain size is refined and bainite transformation occurs to ensure high strength and elongation, as the cooling rate is quick enough. Yield strength and tensite strength improve with the decreased finish cooling temperature, but the elongation decreases too significantly to meet the requirements. Thus, the cooling rate must be quick enough, and the appropriate coiling temperature should be carefully selected to obtain refined ferrite and a small amount of bainite to improve the strength while the plasticity is also ensured. Under this condition, the Mn element concentration can be reduced to save cost or produce higher strength steel with same chemical composition.

Effect of post-coiling transformation on coil collapse of hot-rolled advanced high-strength steel

In this paper, the effect of hot-rolling processing parameters on the post-rolling transformation behavior of C-Mn-Cr-Cu weather-resistant martensitic steel was investigated.Results indicate that the post-rolling transformation behavior, particularly the post-coiling transformation behavior, strongly depends on the coiling temperature.Under a high coiling temperature, ferrite/pearlite transformation was mainly observed with a low trans-formation speed and transformation dilation after coiling.With decreasing coiling temperature, the proportion of bainite transformation increased with an increased transformation speed and transformation dilation.The dependence of transformation behavior on the coiling temperature could be one of the most important reasons behind the coil collapse of the experimental steel.The optimization of hot-rolling and coiling processing parameters of the steel strip, including laminar flow cooling, coiling temperature, and suspension time on the winding machine, can signi-ficantly reduce the transformation dilation of the steel after hot rolling, thus effectively controlling the coil collapse of the steel.

Application research on feedback control based on Dahlin algorithm for coiling temperature of hot strip

To improve the precision of the coiling temperature and the performance of the feedback control system with long pure time delay on hot strip mills, we analyzed the design process of the Dahlin algorithm in detail. The coiling temperature curves controlled by the PID algorithm and Dahlin algorithm were simulated and compared, which showed that the control precision with the Dahlin algorithm was higher than that with the PID algorithm. That was further verified by the production practice.

Developing a Scale for Measuring Uncertainty in Patients with Unruptured Intracranial Aneurysms Undergoing Endovascular Coiling

A measure called the Uncertainty in Unruptured Intracranial Aneurysm Patients Undergoing Endovascular Coiling Scale (UUIACS) was developed and its validity and reliability were examined. The 49 questions that comprised the original draft of the UUIACS were created based on interview data. Based on data from 172 participants, exploratory and confirmatory factor analyses were conducted. As a result of exploratory factor analysis, the UUIACS e retained 17 items and extracted four factors (“Lack of decision-making cues”, “Lack of information and complexity of information interpretation”, “The ambiguous nature of the disease”, and “The unpredictable living with UIA”). All of the UUIACS items showed adequate internal consistency. Between the UUIAC scale and the Universal Uncertainty in Illness Scale (UUIS), the Health Locus of Control (HLC) scale, and the SF-36v2&reg (Japanese version), positive correlations were found between the UUIACS and UUIS, and the HLC scale at a 1% significance level indicating concurrent validity. According to confirmatory factor analysis, the UUIACS had an acceptable goodness of fit. Given these findings, the UUIACS was judged to have satisfied the criteria for use in a clinical setting, although further investigation was required.

Vasospasm as a Complication after Aneurysmal Rupture and Its Relation with Surgical Clipping and Endovascular Coiling among a Georgian Sample

Background: Potentially lethal, aneurysmal subarachnoid hemorrhage has a bad prognosis for many individuals. Over the past few decades, endovascular and surgical interventions have been developed, including surgical clipping, and endovascular coiling. Patients who have aSAH are also susceptible to delayed cerebral ischemia and cerebral vasospasm. The aim of this study is to compare the outcome of endovascular coiling with surgical clipping in patients with SAH, specifically in relation to prevalence of vasospasm, in the country of Georgia. Method: In this study, we present a retrospective review of the outcomes of 217 patients with acute subarachnoid hemorrhage who underwent endovascular coiling or surgical clipping. The data were gathered from patients who are admitted to New Vision University Hospital and Caucasus Medical Center in Tbilisi, Georgia, between 2017 and 2022. Results: Vasospasm was prevalent in 217 of the patients who had aneurysmal rupture when they first appeared. Endovascular coiling or surgical clipping was used to treat aneurysmal rupture. In our sample, 24.81 percent of patients who underwent coiling experienced vasospasm after 14 days, compared to 31.25 percent of patients who underwent clipping. After endovascular coiling and surgical clipping, the severity of vasospasm was only slightly different, according to Lindegaard ratios. Finally, 32 patients (23.35 percent) died after coiling whereas 55 patients (68.75 percent) died within three decades of clipping. Conclusion: After 5 years of data collection, this study has demonstrated the most favorable option for treatment is endovascular coiling. However, the treatment choice takes multiple factors into account, and clipping is not ideal for some ruptured aneurysms. Despite the fact that endovascular coiling is usually successful and minimally invasive, complications can occur and additional monitoring and potential surgical intervention are indicated.

Clipping versus Coiling in Ruptured Aneurysms of the Anterior Cerebral Circulation

Objective: To evaluate and compare the outcomes of microsurgical clipping and endovascular coiling of ruptured anterior cerebral circulation aneurysms. Methods: The current study retrospectively included 61 patients presented with subarachnoid hemorrhage (SAH), treated by clipping or coiling for ruptured aneurysms located in anterior circulation. Anatomic outcome and post-operative ischemic events were evaluated. The primary clinical outcomes were evaluated as operative complications while the secondary clinical outcome was evaluated by modified Rankin scale (mRS) at discharge. Results: Of 61 ruptured aneurysms, 47 and 14 were treated by surgery and coiling, respectively. The average follow-up duration was 19.1 ± 18.6 months for clipping and 21.7 ± 14.8 months for coiling. Complete occlusion was greater in surgery group (80.8%) than endovascular group (21.4%). Re-growth occurred in 2 cases of the coiling group only. Ischemic events were encountered in both groups;silent ones were higher in coiling group (21.4%) than in clipping group (6.3%), while symptomatic ones were higher in the clipping group (49%). Good outcome (mRS 0 - 2) was 51% and 71.4% after clipping and coiling respectively. Postoperative hospital period was longer after clipping (P = 0.04). Conclusions: For anterior circulation ruptured aneurysms, both treatments are feasible, coiling showed lower rate of morbidity while clipping results were better regarding durability and recurrence. Coil embolization may be preferred, which is the current point proved by the RCT like ISAT, but if you choose the patients carefully and find out the optimal candidate for the clipping, the clipping is still enough feasible as a mainstream.

Assisted coiling techniques in treatment of intracranial complex aneurysms

Objective To investigate the application of assisted coiling techniques in the treatment of complex intracranial aneurysms. Methods From Jun. 2007 to Aug. 2010,36 patients with 41 complex intracranial aneurysms were treated by varient endovascular methods,including balloon, stent-assisted coiling and double microcatheter coilingtechniques. Results Among the

Safety and efficacy of complete versus near-complete coiling in treatment of intracranial aneurysms

Objective:This study aimed to evaluate the clinical and angiographic outcomes of aneurysms that were completely or near-completely embolized and ascertain whether complete embolization is important in the stent-assisted coiling(SAC)of intracranial aneurysms.Methods:This retrospective study enrolled 390 patients(417 aneurysms).Among them,complete(100%)or nearcomplete(>90%)angiographic obliteration of the aneurysms on immediate angiography was accomplished.Baseline characteristics,complications,angiography follow-up results,and clinical outcomes were analyzed.Results:Cumulative adverse events occurred in 30 patients(7.7%),including thromboembolic complications in 17(4.4%),intraoperative rupture in 10(2.6%),and others in 3(0.8%).Statistical analyses revealed an increased intraprocedural rupture rate in the initial completely occluded aneurysms(5.6%compared with 1.0%).The incidence of cumulative adverse events was higher in patients with completely occluded aneurysms(11.1%)than in those with near-completely occluded aneurysms(5.5%).Angiography follow-up was available for 173 aneurysms.Aneurysm occlusion status at follow-up was correlated with stent placement(p?0.000,odds ratio?5.847),size(p?0.000,odds ratio?6.446 for tiny aneurysms;and p?0.001,odds ratio?5.616 for small aneurysms),and initial aneurysm occlusion status(p?0.001,odds ratio?3.436).Complete occlusion at followup was seen in 82.6%of the initial complete occlusion group versus 63.0%of the initial near-complete occlusion group.The incidence of complete occlusion at follow-up was higher in the initial completely occluded aneurysms with SAC(100%)than in the initial completely occluded aneurysms with non-SAC(65.2%).Conclusions:Initial complete treatment may lead to higher complication rates and good clinical outcomes at follow-up.Stent placement may enhance progressive aneurysm occlusion.Initial complete occlusion with SAC can provide durable closure at follow-up.

鞣花酸对大肠杆菌感染肉鸡生长性能和抗氧化功能的影响

本试验旨在研究鞣花酸(EA)对大肠杆菌感染肉鸡生长性能和抗氧化功能的影响。实验选用216只1日龄遗传背景相同、体重均一、健康的罗斯308肉雏鸡,按照单因素试验设计,随机分为对照组、E.coil K88组和E.coil K88+EA组3个处理组,每组6个重复,每个重复有12羽(公母各半)。对照组和E.coil K88组肉鸡饲喂基础饲粮,E.coil K88+EA组肉鸡饲喂含200 mg/kg EA的基础饲粮。E.coil K88组和E.coil K88+EA组肉鸡在第10日龄口腔灌服1mL E.coil K88菌悬液,对照组灌服1 mL无菌LB培养基。试验期42 d。结果显示:①与对照组相比,E.coil K88感染有降低1~42日龄肉鸡平均日采食量(ADFI,P=0.05)和平均日增重(ADG,P=0.054)的趋势,同时提高了42日龄肉鸡胸腺器官指数、21日龄肉鸡血清谷草转氨酶(ALT)、碱性磷酸酶(ALP)活性、尿酸(UA)和过氧化氢(H_(2)O_(2))含量(P<0.05),提高42日龄肉鸡空肠髓过氧化物酶(MPO)活性以及十二指肠IL-17、空肠和回肠IL-8的mRNA水平(P<0.05);E.coil K88感染降低了21日龄肉鸡十二指肠和空肠过氧化氢酶(CAT)、总超氧化物歧化酶(T-SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性(P<0.05),也降低了42日龄肉鸡十二指肠CAT活性及空肠CAT、GSH-Px活性(P<0.05)。②与感染组相比,饲粮中添加EA提高了21日龄肉鸡血浆GSH-Px活性、十二指肠的CAT、GSH-Px活性、回肠GSH-Px活性,42日龄肉鸡十二指肠CAT、T-SOD、GSH-Px活性及空肠CAT、GSH-Px活性(P<0.05),还降低了21日龄肉鸡血清ALP活性以及十二指肠丙二醛(MDA)含量和一氧化氮合成酶(i-NOS)活性(P<0.05)。与感染组相比,日粮中添加EA下调了42日龄血清UA含量和MPO活性、十二指肠MPO活性、空肠MPO含量与i-NOS活性、十二指肠IL-17、空肠IL-8以及回肠IL-17、IL-8的转录水平(P<0.05)。由以上可知,日粮中添加200 mg/kg鞣花酸可改善大肠杆菌感染肉鸡生长性能和血液生化指标,增强其抗氧化和免疫功能。

Modeling of Stress Distribution During Strip Coiling Process

Many strip materials are coiled after rolling process. The stresses are imposed on the material wound on the automatically controlled collapse mandrel under the coiling tension. The coiling process can be described by three typical cases: winding without automatic adjustment, winding with automatic adjustment and after mandrel removal. A new model of equations for predicting the stresses during the strip coiling process is built by consideration of the three cases respectively. By solving the equations of different typical cases, the radial stresses and tangential stress of the layers of coil can be calculated. Also, the coiling parameters, such as strip thickness, coiling tension and necking critical pressure, affecting the coil performance are investigated. It is believed that the present model can be used for design and control of the automatically controlled collapse mandrel.

Endovascular Coiling for a Ruptured Proximal Lenticulostriate Artery Aneurysm

Aneurysms of the lenticulostriate artery （LSA） are rare lesions that are categorized into either proximal （at the junction of the middle cerebral artery trunk） or distal （within the basal ganglia）.

Microstructure, property and deformation and fracture behavior of 800 MPa complex phase steel with different coiling temperatures

The microstructure characteristics and properties(especially hole expansion property)of 800 MPa hot-rolled complex phase steel with different coiling temperatures were studied.The microstructure consisted of polygonal ferrite and precipitates when the steel was coiled at 550℃,and when the steel was coiled between 460–520℃,the microstructure was composed of granular bainite and martensite and austenite(M/A)islands.The morphology of the crack was analyzed by scanning electron microscopy,and the in situ scanning electron microscope tensile test was used to find out the fracture mechanism and deformation behavior of the steel with different coiling temperatures.When the steel was coiled at 550℃,the cracks initiated at the ferrite grain boundary and propagated through the grains or along the grain boundaries.When the steel was coiled at 520℃,the cracks first initiated at the junction of ferrite and M/A island and then propagated through the grains.The steel coiled at 520℃ has quite good mechanical properties and relatively high hole expansion ratio.

Effects of Coiling Temperature and Cooling Condition on Transformation Behavior of Tertiary Oxide Scale

The influences of coiling temperature and cooling condition on structural transformation of the hot-rolled tertiary oxide scale formed under continuous cooling conditions were studied by thermal gravimetric analyzer. The fourth oxide scale formed under different conditions were classified and plotted. Because the oxide scale structure transformation is diffusion-controlled and the transformation law is similar to ＂C＂ curve, the eutectoid transformation nose temperature is 450 ℃. Under condition of low temperature and high cooling rate, ion diffusion behavior is restricted so that the eutectoid reaction is suppressed, resulting in that the fourth oxide scale is mainly made up of pre-eutectoid Fe304 and FeO without eu- tectoid products. From scale structure transition diagram, the eutectoid reaction process was affected by coiling temperature and cooling rate, leading to various scale structures.

Influence of coiling temperature on microstructure and mechanical properties of a hot-rolled high-strength steel microalloyed with Ti,Mo and V

Influence of coiling temperature(CT)on the microstructure and mechanical properties of a hot-rolled high-strength steel microalloyed with Ti,Mo and V was elucidated.The precipitation behavior of nano-sized particles was investigated by theoretical calculation and quantitative analysis.And the results revealed that V-enriched(Ti,Mo,V)C precipitated in the ferrite matrix.As the CT decreased,the site fractions of Ti in(Ti,Mo,V)C changed little,the site fractions of Mo increased,and the site fractions of V decreased accordingly.Moreover,the low CT could refine the microstructure and precipitated particles but suppress the precipitation of(Ti,Mo,V)C particles simultaneously,leading to the volume fraction of(Ti,Mo,V)C significantly decreasing,consequently causing an increment of grain refinement strengthening and a reduction in precipitation hardening.When the CT was 600℃,the steel characterized by fine polygonal ferrite,a small amount of bainite and nano-sized(Ti,Mo,V)C precipitates exhibited the optimum mechanical properties with the ultimate tensile strength of 870 MPa,yield strength of 807 MPa and elongation to fracture of 17%.