BACKGROUND Indeterminate dendritic cell tumor(IDCT)is a rare tumor of immune cells,and IDCT patients without skin lesions are rarely reported.Therefore,the clinical course in this type of patient is unclear,and furthe...BACKGROUND Indeterminate dendritic cell tumor(IDCT)is a rare tumor of immune cells,and IDCT patients without skin lesions are rarely reported.Therefore,the clinical course in this type of patient is unclear,and further research on the underlying pathological mechanisms and appropriate treatments is needed.CASE SUMMARY This study describes a female IDCT patient with bile duct lesions.The strong mimicry of IDCT lesions confused doctors,and consequently,this patient,who had no skin lesions,was first diagnosed with cholangiocarcinoma.Then,she presented with persistent abdominal distension without jaundice.Enlarged mesenteric lymph nodes along with massive ascites were observed in the subsequent imaging examination.However,no tumor cells or pathogens were found in the three subsequent ascites analyses.It took 2 years to reach the correct diagnosis,which was eventually obtained by performing surgery for biopsy of the patient’s abdominal lymph nodes.However,by then,she was already in a cachexic state.Finally,she received a cycle of cyclophosphamide therapy and was advised to visit a hospital specializing in rare diseases.CONCLUSION For IDCT patients without skin lesions,early biopsy is the key to obtaining a correct diagnosis.Moreover,the collective management of IDCT patients is important.Further histological and molecular biology studies based on human specimens are critical for understanding the pathological mechanism of dendritic cell tumors in the future.展开更多
Purpose: To meet the changing needs of academic and specialized users,university and research libraries are transforming their collections,staff,and services. At the UCLA Library,four principles underlie changes that ...Purpose: To meet the changing needs of academic and specialized users,university and research libraries are transforming their collections,staff,and services. At the UCLA Library,four principles underlie changes that have been made to support teaching,learning,and research by UCLA students,faculty,researchers,and staff. Efforts have focused on building and enhancing research collections,enriching the student experience through expanded teaching and learning services,transforming the Library's role to support the entire research process,and re-conceptualizing the physical and virtual spaces of the Library to create an expansive and flexible scholarly environment. To support and inform these efforts,the Library is building a robust research agenda and deepening opportunities for faculty engagement.These changes challenge the traditional model of library staffing,and the Library has responded by identifying new areas in which leadership is needed and new recruitment tracks for academic appointments. Implementing such a transformative process has many stakeholders and requires broad input,discussion,and committed engagement to ensure its success.Design/methodology/approach: The UCLA Library has developed its strategic planning process over several years building on broad constituent input,unit and individual work plans,and constituent feedback. The process is high level as well as operational in nature and draws on basic metrics to motivate change.Findings: The four principles of the transition have been sustained over a period of years.Implications and limitations: This article is the personal observation of the author drawing on his own leadership experience and informed by the senior management and staff of the UCLA Library.Originality/value: The process and direction of this transition are focused on the UCLA Library and its role in the UCLA academy.展开更多
Since 2013,optimizing the business environment has become China's national strategy.In recent years,the Party and the government have continuously introduced a series of new measures such as the'"streamli...Since 2013,optimizing the business environment has become China's national strategy.In recent years,the Party and the government have continuously introduced a series of new measures such as the'"streamline administration,delegate power,strengthen regulation,and improve services55 reform to promote the continuous optimization of the business environment.As an important part of the business environment,the tax business environment is of great significance to improve the business environment and promote economic development.By analyzing the current situation of the tax business environment in China,this article discusses the existing problems in the process of optimizing tax business environment in China.Taking Shunde Taxation Bureau's innovative reform of tax business environment optimization as an example,this article introduces the practical innovation and promotion of optimizing tax business environment from four aspects:promoting convenience,digitalization,legalization,and intensive reform,in order to provide relevant experience for the optimization of tax business environment in other areas of China.展开更多
This paper describes shop floor data collection and management. An architecture is presented for a shop floor data collection and management system based on the analysis of the features of these data. Two critical asp...This paper describes shop floor data collection and management. An architecture is presented for a shop floor data collection and management system based on the analysis of the features of these data. Two critical aspects of the system are discussed in detail: the various communication protocols between computers and machines, and the real time demands of the shop floor controller.展开更多
The optimization and upgrading of industrial structure is the driving force to build a new development pattern and improve the quality and efficiency of economic development.China's"pressure-type"fiscal ...The optimization and upgrading of industrial structure is the driving force to build a new development pattern and improve the quality and efficiency of economic development.China's"pressure-type"fiscal incentives(PTFIs)are an important perspective from which the law of industrial structure change can be analyzed.Based on the dynamic panel data of 285 cities in China and the behavioral characteristics of local governments,this paper explores the effects of PTFIs on industrial restructuring using the GMM estimation method.It is found that PTFIs are conducive to improving the"quantity"of industrial structure upgrading(ISU),but not conducive to improving the"quality"of ISU or the rationalization of industrial structure(RIS).Mechanism identification reveals that,with PTFIs,local governments influence industrial restructuring mainly by"expanding financial resources with land"(EFRWL)and increasing the intensity of tax collection and management(ITCM).Further discussion reveals that a higher degree of fiscal decentralization and environmental regulation can effectively alleviate the negative impact of PTFIs on industrial restructuring.Accordingly,this paper puts forward some policy recommendations to promote the balanced development of industrial structure,such as improving the institutional conditions and standardizing the behavior of local governments.展开更多
文摘BACKGROUND Indeterminate dendritic cell tumor(IDCT)is a rare tumor of immune cells,and IDCT patients without skin lesions are rarely reported.Therefore,the clinical course in this type of patient is unclear,and further research on the underlying pathological mechanisms and appropriate treatments is needed.CASE SUMMARY This study describes a female IDCT patient with bile duct lesions.The strong mimicry of IDCT lesions confused doctors,and consequently,this patient,who had no skin lesions,was first diagnosed with cholangiocarcinoma.Then,she presented with persistent abdominal distension without jaundice.Enlarged mesenteric lymph nodes along with massive ascites were observed in the subsequent imaging examination.However,no tumor cells or pathogens were found in the three subsequent ascites analyses.It took 2 years to reach the correct diagnosis,which was eventually obtained by performing surgery for biopsy of the patient’s abdominal lymph nodes.However,by then,she was already in a cachexic state.Finally,she received a cycle of cyclophosphamide therapy and was advised to visit a hospital specializing in rare diseases.CONCLUSION For IDCT patients without skin lesions,early biopsy is the key to obtaining a correct diagnosis.Moreover,the collective management of IDCT patients is important.Further histological and molecular biology studies based on human specimens are critical for understanding the pathological mechanism of dendritic cell tumors in the future.
文摘Purpose: To meet the changing needs of academic and specialized users,university and research libraries are transforming their collections,staff,and services. At the UCLA Library,four principles underlie changes that have been made to support teaching,learning,and research by UCLA students,faculty,researchers,and staff. Efforts have focused on building and enhancing research collections,enriching the student experience through expanded teaching and learning services,transforming the Library's role to support the entire research process,and re-conceptualizing the physical and virtual spaces of the Library to create an expansive and flexible scholarly environment. To support and inform these efforts,the Library is building a robust research agenda and deepening opportunities for faculty engagement.These changes challenge the traditional model of library staffing,and the Library has responded by identifying new areas in which leadership is needed and new recruitment tracks for academic appointments. Implementing such a transformative process has many stakeholders and requires broad input,discussion,and committed engagement to ensure its success.Design/methodology/approach: The UCLA Library has developed its strategic planning process over several years building on broad constituent input,unit and individual work plans,and constituent feedback. The process is high level as well as operational in nature and draws on basic metrics to motivate change.Findings: The four principles of the transition have been sustained over a period of years.Implications and limitations: This article is the personal observation of the author drawing on his own leadership experience and informed by the senior management and staff of the UCLA Library.Originality/value: The process and direction of this transition are focused on the UCLA Library and its role in the UCLA academy.
文摘Since 2013,optimizing the business environment has become China's national strategy.In recent years,the Party and the government have continuously introduced a series of new measures such as the'"streamline administration,delegate power,strengthen regulation,and improve services55 reform to promote the continuous optimization of the business environment.As an important part of the business environment,the tax business environment is of great significance to improve the business environment and promote economic development.By analyzing the current situation of the tax business environment in China,this article discusses the existing problems in the process of optimizing tax business environment in China.Taking Shunde Taxation Bureau's innovative reform of tax business environment optimization as an example,this article introduces the practical innovation and promotion of optimizing tax business environment from four aspects:promoting convenience,digitalization,legalization,and intensive reform,in order to provide relevant experience for the optimization of tax business environment in other areas of China.
文摘This paper describes shop floor data collection and management. An architecture is presented for a shop floor data collection and management system based on the analysis of the features of these data. Two critical aspects of the system are discussed in detail: the various communication protocols between computers and machines, and the real time demands of the shop floor controller.
文摘The optimization and upgrading of industrial structure is the driving force to build a new development pattern and improve the quality and efficiency of economic development.China's"pressure-type"fiscal incentives(PTFIs)are an important perspective from which the law of industrial structure change can be analyzed.Based on the dynamic panel data of 285 cities in China and the behavioral characteristics of local governments,this paper explores the effects of PTFIs on industrial restructuring using the GMM estimation method.It is found that PTFIs are conducive to improving the"quantity"of industrial structure upgrading(ISU),but not conducive to improving the"quality"of ISU or the rationalization of industrial structure(RIS).Mechanism identification reveals that,with PTFIs,local governments influence industrial restructuring mainly by"expanding financial resources with land"(EFRWL)and increasing the intensity of tax collection and management(ITCM).Further discussion reveals that a higher degree of fiscal decentralization and environmental regulation can effectively alleviate the negative impact of PTFIs on industrial restructuring.Accordingly,this paper puts forward some policy recommendations to promote the balanced development of industrial structure,such as improving the institutional conditions and standardizing the behavior of local governments.
