Therapeutic Effect of Oral Administration and External Therapy of Traditional Chinese Medicine on Cervical Tuberculous Lymphadenopathy

Objective:To analyze the clinical effect and value of oral administration and external therapy of traditional Chinese medicine for treatment of cervical tuberculous lymphadenopathy.Methods:A total of 56 patients with cervical tuberculous lymphadenopathy admitted to our hospital from January 1 to January 2018 were recruited.By using double-blind method,the patients were divided into control group(n=28)and experimental group(n=28).Control group comprised of patients with conventional anti-tuberculosis treatment,while the experimental group comprised of patients treated with oral administration and external therapy of traditional Chinese medicine.Total effective rate,incidence of complication and level of T lymphocyte subsets were compared between the two groups of cervical tuberculous lymphadenopathy patients.Results:Post-treatment data of total effective rate,complication rate,CD3+,CD4+,CD8+,CD4+/CD8+of the experimental group were compared with the control group.P<0.05;statistical analysis showed statistical significance.Post-treatment data of CD3+,CD4+,CD8+,CD4+/CD8+of both control and experimental groups were compared with pre-treatment data.P<0.05;statistical analysis showed statistical significance.Conclusion:Oral administration and external therapy of traditional Chinese medicine possesses significant effect in treatment of cervical tuberculous lymphadenopathy.

TREATMENT OF 50 CASES OF SENILE DEMENTIA BY ACUPUNCTURE COMBINED WITH INHALATION OF HERBAL DRUGS AND OXYGEN

Clinical DataCase selection: 100 cases who met thediagnostic criteria of senile dementiaformulated by American Association ofPsychiatry in Handbook of Diagnosis andStatistics (DSM-Ⅲ-R, 3rd revised edition)

The Method of Combining Internal and External Treatment of Ulcerative Colitis in Chinese Medicine

Traditional Chinese medicine(TCM)believes that the main pathogenesis of ulcerative colitis is spleen deficiency;damp heat in the large intestine as the symptom,the treatment must be warming,clearing,eliminating,tonifying,astringing concurrently.From the concept of combining holism and the local treatment in TCM,idea of combining internal and external treatment is adopted.That is,the external treatment follows the therapeutic principle of using herbs with a bitter and cold nature to eliminate stagnation,and the seven carbon decoction,which can clear heat and dampness,cool the blood,and stop dysentery,is used as a rectal drip to retain the enema.Internal treatment follows the therapeutic principle of warmly tonifying and cultivating vital qi,with oral Chinese herbal medicine named Maodie Tang to strengthen the spleen and tonify the kidney,clearing heat and inducing dampness.

Clinical Observation on Treatment of Acquired Paralytic Strabismus by Acupuncture Plus Oral Administration of Chinese Herbs

From June 1996 to June 2002, the author treated 38 cases of acquired paralytic strabismus by acupuncture plus oral administration of Zheng Rong Tang (正容汤), with another 38 cases of acquired paralytic strabismus treated only with oral administration of Chinese herbs as the controls. The results are reported as follows.

Differential Treatment for Membranoproliferative Glomerulonephritis with TCM Prescriptions Plus Triptoryph Tablets A Report of 30 Cases

Membranoproliferative glomerulonephritis is aglomerulopathy,which accounts for about 30% of thechronic glomerulonephritis in adults.TCMmedication with addition of triptoryph tablets(Tripterygium Wilfordii polyglycosidium) on thebasis of syndrome differentiation had yieldedsatisfactory results in 30 cases of this disease treatedfrom Jan 1998 to Aug 2002.A report follows.

甘精胰岛素U300联合口服降糖药治疗2型糖尿病的临床效果观察

目的探讨甘精胰岛素U300联合口服降糖药治疗2型糖尿病的临床效果。方法选择2021年10月—2023年1月广东省吴川市人民医院收治的79例2型糖尿病患者,随机分为非甘精组(39例)和U300组(40例)。非甘精组口服降糖药物治疗,在此之上,U300组增加甘精胰岛素U300治疗,持续治疗3个月,对比2组血糖及相关指标变化,并监测患者胰岛素功能相关指标改善情况,评估低血糖反应等不良反应情况。结果治疗后,U300组血糖指标、血糖波动指标均显著低于非甘精组,差异有统计学意义(P<0.05)。U300组治疗后胰岛素功能指标均显著优于非甘精组,空腹及餐后2 h C肽均显著高于非甘精组,差异有统计学意义(P<0.05)。U300组低血糖反应发生率(2.50%,1/40)和不良反应总发生率(20.00%,8/40)与非甘精组(2.56,1/39;17.95%,7/39)比较,差异无统计学意义(P>0.05)。结论增加甘精胰岛素U300治疗,可更好地提升患者血糖管理效果,并可改善胰岛功能,有利于稳定控制血糖,有助于提高患者病情控制效果,应用效果安全可靠。

Clinical Observation on the Combined Use of Acupuncture and Herbal Medicine for Treatment of Chloasma

Objective:To observe the clinical effects of the combined use of acupuncture and herbal medicine for treatment of chloasma.Methods:Totally 60 patients were randomly divided into a treatment group of 30 cases,treated by acupuncture and herbal medicine,and a control group of 30 cases,administered Vitamin C and Vitamin E.The clinical effects were observed.Results:The total effective rate of the treatment group is 93.3%better than that of the control group(76.7%) ,the difference was significant(P<0.01) .Conclusion:Combined use of acupuncture and herbal medicine may yield definite therapeutic effects in treating chloasma patients.

Long-term Effect of TCM Decoctions in Treatment of Nephrotic Syndrome

Fifty-seven cases of nephrotic syndrome were treated with TCM decoctions as accessory treatment for prednisone and cyclophosphamide, and the effects were observed in a follow-up period of 5-15 years. The long-term complete remission rate of 68.4% and recurrence rate of 26.3% in the treatment group were respectively higher and lower than those in the control group (P<0.01, and P<0.01). The results suggested that the TCM decoctions were very helpful in treating this condition.

Clinical Application of the Point Yongquan

Yongquan (KI 1) is a jing (well) point of the Kidney Meridian of Foot-Shaoyin. As this point is widely used for treatment of acute or chronic diseases, it has drawn attentions from physicians both in the ancient and in the present times. If this point is taken accurately and the differentiation of disease is made properly, both the needling and the external drug application can achieve satisfactory therapeutic results.

Fifty-Six Cases of Acne Treated by Auricular Needle-Embedding

Acne is an inflammatory disease often affecting the boys and girls at the pubescent age, with a tendency of affecting the females aged 30-45 years. We have treated 56 cases of acne by auricular needle-embedding with satisfactory therapeutic results as reported in the following.……

Application of Bu Zhong Yi Qi Tang According to TCM Differentiation of Syndromes

Bu Zhong Yi Qi Tang (补中益气汤Decoction for Reinforcing the Middle-jiao and Replenishing Qi) is an effective formulated recipe commonly used for treating a variety of diseases with the manifestations of kidney-qi deficiency. In my opinion, however, it is also very effective for the conditions of which the symptoms of kidney-qi deficiency is not noticeable, but its mechanism lies in dysfunction of the spleen. The following are some examples.……

The Thinking on TCM Differential Treatment of Congestive Heart Failure

Congestive heart failure(CHF),the manifestationat the late stage of cardiovascular diseases,is a commonand critical illness.Traditional Chinese medicine showsa good therapeutic effectiveness in treatment of CHF,especially for latent heart failure,refractory heart failureand digitalis poisoning.The thinking on treatment ofCHF by traditional Chinese medicine on the basis ofclinical practice is described below.

妇产科实施慢性盆腔炎临床治疗的方法及效果分析

目的:探析慢性盆腔炎(CPID)临床治疗的方法及效果。方法:纳入本院2020年1月至2022年12月收治共计200例CPID患者,采用简单随机化方法将纳入患者均分且设定为对照组、观察组(均n=100),前一组给予常规西医治疗,后一组加施中成药口服+红外线腹部照射+低频脉冲电治疗,比较两组临床效果、症状缓解时间、中医症候积分、血液流变学指标以及炎症因子水平和不良反应发生情况。结果:观察组临床总有效率93.00%较对照组的82.00%居于更高水平(P<0.05)。观察组下腹坠胀、下腹疼痛以及腰骶部酸痛等症状缓解时间均较对照组更短(P<0.05)。治疗前,两组下腹胀痛或刺痛、带下色黄质稠量多、胸闷纳呆、经期长量大色黯红等症候评分均无差异(P>0.05);治疗2周,观察组各项症候评分均较对照组更低(P<0.05)。治疗前,两组ESP、CP、PV、FIB水平均无统计学差异(P>0.05);治疗2周,观察组ESP、CP、PV、FIB水平均较对照组更低(P<0.05)。治疗前,两组IL-8、IL-10、TGF-β1、MCP-1水平均无统计学差异(P>0.05);治疗2周,观察组IL-8、TGF-β1、MCP-1水平均较对照组更低,IL-10水平较对照组更高(P<0.05)。观察组头晕、恶心、皮疹等常见不良反应总发生率4.00%与对照组的6.00%比较无统计学差异(P>0.05)。结论:于CPID患者而言,在常规西医治疗基础上加施中成药口服+红外线腹部照射+低频脉冲电治疗,能够取得理想效果,且安全性较高,值得应用。

消瘰散结散联合常规抗结核药物治疗浸润型淋巴结结核的疗效观察

目的:观察消瘰散结散联合常规抗结核药物治疗浸润型浅表淋巴结结核临床疗效及对免疫水平影响。方法:采用前瞻性研究的方法,参照入组标准选择2019年3月至2021年3月于河北省胸科医院住院治疗的80例确诊为浸润型浅表淋巴结结核患者,按照随机数字表法将80例患者平均分为观察组40例(常规抗结核治疗+消瘰散结散组)和对照组40例(常规抗结核治疗组)。观察两组患者治疗2个月时的临床有效率、中医证候(疼痛、低热、乏力、盗汗)积分变化、免疫水平(CD3^(+)、CD4^(+)、CD8^(+)水平和CD4/CD8比值),以及治疗10个月疗程结束时的治愈率、随访情况及不良反应。在2个月强化期治疗结束时,观察组和对照组分别脱落1例和3例。结果:两组患者治疗2个月时,观察组总有效率[97.4%(38/39)]明显高于对照组[83.8%(31/37)],差异有统计学意义(χ^(2)=4.232,P=0.040);观察组在疼痛、低热、乏力、盗汗等中医证候的积分改善情况[分别为(0.38±0.08)、(0.38±0.08)、(0.56±0.08)、(0.41±0.08)分]和CD3^(+)、CD4^(+)水平及CD4/CD8比值[分别为(66.89±3.58)%、(39.92±3.73)%和1.47±0.23]均优于对照组[分别为(0.76±0.10)、(0.68±0.09)、(0.92±0.09)和(0.68±0.08)分;(62.68±3.61)%、(32.19±2.96)%和1.06±0.12],而CD8^(+)水平[(26.81±2.99)%]低于对照组[(30.81±2.56)%],差异均有统计学意义(t=-2.971,P=0.040;t=-2.481,P=0.015;t=-2.948,P=0.004;t=-2.375,P=0.020;t=5.101,P<0.001;t=9.989,P<0.001;t=9.447,P<0.001;t=-6.245,P<0.001)。治疗10个月疗程结束时,观察组治愈率[100.0%(39/39)]明显高于对照组[86.5%(32/37)],差异有统计学意义(χ^(2)=5.641,P=0.024);且前者皮肤无破溃,后者3例(8.1%)皮肤破溃、2例(5.4%)未愈持续用药。观察组治疗期间不良反应发生率[5.1%(2/39)]与对照组[8.1%(3/37)]差异无统计学意义(χ^(2)=0.274 P=0.671)。结论:消瘰散结散联合常规抗结核药物可提高浸润型浅表淋巴结结核患者免疫水平、临床疗效、治愈率、改善中医证候,且安全性较好,可临床广泛应用。

中药口服联合外用疗法治疗HR-HPV持续性感染的临床有效性及安全性分析

目的 探讨中药口服联合外用疗法治疗HR-HPV持续性感染的临床有效性及安全性。方法 将2021年1月-2022年12月在本院妇产科治疗的120例HR-HPV持续性感染患者随机分为两组,对照组使用保妇康栓治疗,观察组使用中药口服联合外用疗法,对比两组的临床疗效、免疫炎性因子、阴道分泌物指标、安全性。结果 观察组治疗有效率明显高于对照组(P<0.05);观察组治疗后阴道灌洗液中IL-2、IFN-γ水平明显高于对照组,IL-4水平明显低于对照组(P<0.05);观察组治疗后阴道分泌物pH值、Nugent评分明显低于对照组(P<0.05);观察组治疗后WBC、RBC、Hb、AST、ALT、BUN、Scr水平均与对照组相当(P>0.05)。结论 中药口服联合外用疗法治疗HR-HPV持续性感染的临床疗效显著,对HR-HPV的抑制力强,能有效调节宫颈免疫功能,改善阴道内环境,且安全性好。

健脾滋肾法针药合用治疗低言语识别性耳聋的疗效观察

目的比较健脾滋肾法指导下针药合用治疗低言语识别率耳聋患者的临床疗效。方法2017年6月~2019年12月在四川省成都中医药大学附属医院、四川省峨眉山市中医院和四川大学望江校区医院就诊本病患者203例,分为实验组共68例82耳,采用针药合用治疗;对照组1共67例80耳,单用针刺治疗;对照组2共68例80耳,单用中药治疗。分别在治疗第0d、2w、4w和6w4个时间窗对3个组患者行听阈及言语识别率测定,疗程结束后随访半年。比较分析3个治疗时间窗口各组疗效差异。结果在治疗周期内,三组患者的纯音听阈阈值均随治疗时间的延长而提升。在不同治疗阶段,实验组与对照组1及对照组2的治疗结果组间比较差异有统计学意义(P<0.05),言语识别率均随着治疗时间增加而提升,但对照组1与对照组2的组间比较差异无性统计学意义(P>0.05)。结论健脾滋肾法指导下的针刺、中药及针药合用均能改善低言语识别性耳聋患者听阈水平及言语识别率,尤以针药合用组疗效最佳。

吴门女科温阳通络方口服联合外敷治疗子宫内膜异位症临床研究

目的:观察温阳通络方口服联合外敷治疗寒凝血瘀型子宫内膜异位症的临床疗效。方法:将90例子宫内膜异位症患者随机分为口服组、外敷组、口服+外敷组,每组各30例。3组分别给予温阳通络方口服、温阳通络方外敷、温阳通络方口服+外敷治疗,观察3组治疗后中医证候评分、局部体征评分、疼痛程度(VAS)评分、异位囊肿体积大小、双侧子宫动脉血流阻力指数、血清CA125水平,评价临床综合疗效。结果:各组患者治疗前年龄、病程、既往相关手术次数等基线资料、中医证候评分、局部体征评分、疼痛程度评分、异位囊肿体积、双侧子宫动脉血流阻力指数、血清CA125水平,差异均无统计学意义(P>0.05)。治疗后各组中医证候评分、局部体征评分、疼痛程度评分、异位囊肿体积、双侧子宫动脉血流阻力指数、血清CA125水平均有下降(P<0.05)。治疗后口服+外敷组中医证候总积分、次症积分明显低于其他两组(P<0.05),主症积分明显低于口服组(P<0.05),但与外敷组相比差异无统计学意义(P>0.05);治疗后口服+外敷组疼痛程度评分明显低于其他两组(P<0.05),口服+外敷组中局部体征积分、双侧子宫动脉血流阻力指数、CA125水平明显低于其他两组(P<0.05)。结论:温阳通络方口服联合外敷治疗寒凝血瘀型子宫内膜异位症临床综合疗效明显,能缓解患者痛经程度,改善患者临床症状,提高患者生活质量;另外还能加速患者局部体征的减轻,改善局部微循环状态,下调患者生物学标志物血清CA125的水平。

“四辨三法”在股骨头坏死中医临床诊治中的运用

股骨头坏死(osteonecrosis of the femoral head,ONFH)是骨科临床常见且难治性疾病,早期多无明显症状和体征,容易造成误诊和漏诊。“四辨”即辨病(辨病因病机、发生、发展和预后)、辨证(辨中医证型)、辨位(辨病邪所影响的局部与整体)、辨体(辨患者体质)相结合,是以四诊信息为基础的一种更加整体、规范的中医诊断模式;“三法”即内服中药、针药外治(中药热敷结合针刀疗法)、动静结合(康复过程中需动静结合)。“四辨三法”用于股骨头坏死的中医临床诊治,可实现早期精确诊断,有效防治股骨头坏死。

膝关节半月板损伤的保守治疗研究进展

中医治疗膝关节半月板损伤主要采用中药内服、中药熏洗、中药外敷、针灸疗法、推拿疗法、中医综合疗法等;西医治疗膝关节半月板损伤主要包括关节腔穿刺冲洗、口服非甾体抗炎药、关节腔注射玻璃酸钠、盐酸氨基葡萄糖治疗、关节腔注射富血小板血浆、关节腔注射臭氧、关节腔注射干细胞等。保守治疗对于大部分半月板损伤患者有较好疗效,避免了手术治疗带来的创伤、软骨损伤、膝骨关节炎等远近期并发症,但对于膝关节半月板损伤有弹响和交锁症状的患者,疗效不佳,应该尽早行手术治疗。目前,保守治疗方法众多,但疗效评判标准不统一,针对半月板损伤类型的治疗标准,缺少统一高效的一种或几种联合保守治疗方法。今后,应进一步研究如何运用合理高效的保守治疗方法对半月板损伤进行治疗,提高患者生活质量。