Critics have pointed at new technologies as cutprits in the decline of civic life, neighboring and social capital construction in Western societies. When applied to community design and ptanning processes, technologie...Critics have pointed at new technologies as cutprits in the decline of civic life, neighboring and social capital construction in Western societies. When applied to community design and ptanning processes, technologies can empower residents to actively engage in decision-making, foster connections across social groups, with positive consequences on life and sociatization in public spaces. What kind of participation do technotogies foster? And is it the kind that bridges social and ideotogical divides? The 2012 community design process for Hawthorne Park in Medford, Oregon illustrates many of the challenges and opportunities connected to the use of new technologies in design. In the process, technologies were instrumental in enlisting a larger-than-usual number of residents to participate in the design of the park. Blogs and online questionnaires were successful in gathering people's thoughts on the design choices being made, but also favored a limited, intermittent form of engagement. The results are synthesized in principles for the successful integration of web-based technologies in future community design efforts: adaptability, fuji participation, nuanced participation and the need for links to the physical realm.展开更多
Background:Synthetic microbial communities,with different strains brought together by balancing their nutrition and promoting their interactions,demonstrate great advantages for exploring complex performance of commun...Background:Synthetic microbial communities,with different strains brought together by balancing their nutrition and promoting their interactions,demonstrate great advantages for exploring complex performance of communities and for further biotechnology applications.The potential of such microbial communities has not been explored,due to our limited knowledge of the extremely complex microbial interactions that are involved in designing and controlling effective and stable communities.Results:Genome-scale metabolic models(GEM)have been demonstrated as an effective tool for predicting and guiding the investigation and design of microbial communities,since they can explicitly and efficiently predict the phenotype of organisms from their genotypic data and can be used to explore the molecular mechanisms of microbehabitats and microbe-microbe interactions.In this work,we reviewed two main categories of GEM-based approaches and three uses related to design of synthetic microbial communities:predicting multi-species interactions,exploring environmental impacts on microbial phenotypes,and optimizing community-level performance.Conclusions:Although at the infancy stage,GEM-based approaches exhibit an increasing scope of applications in designing synthetic microbial communities.Compared to other methods,especially the use of laboratory cultures,GEM-based approaches can greatly decrease the trial-and-error cost of various procedures for designing synthetic communities and improving their functionality,such as identifying community members,determining media composition,evaluating microbial interaction potential or selecting the best community configuration.Future efforts should be made to overcome the limitations of the approaches,ranging from quality control of GEM reconstructions to community-level modeling algorithms,so that more applications of GEMs in studying phenotypes of microbial communities can be expected.展开更多
As urban renewal shifts to more routine community renewal, the design methods of community renewal are faced with new challenges. Considering the existing dilemma faced by old communities and based on the practice of ...As urban renewal shifts to more routine community renewal, the design methods of community renewal are faced with new challenges. Considering the existing dilemma faced by old communities and based on the practice of community renewal of different scales in recent years, this paper proposes that the design for community renewal should consider not only the spatial structure of communities at the macro level, but also the needs of daily life at the micro level. It can help efficiently transform the existing space into public space that encourages residents’ participation and promote community vitality, to achieve a humanistic value beyond the physical environment.展开更多
文摘Critics have pointed at new technologies as cutprits in the decline of civic life, neighboring and social capital construction in Western societies. When applied to community design and ptanning processes, technologies can empower residents to actively engage in decision-making, foster connections across social groups, with positive consequences on life and sociatization in public spaces. What kind of participation do technotogies foster? And is it the kind that bridges social and ideotogical divides? The 2012 community design process for Hawthorne Park in Medford, Oregon illustrates many of the challenges and opportunities connected to the use of new technologies in design. In the process, technologies were instrumental in enlisting a larger-than-usual number of residents to participate in the design of the park. Blogs and online questionnaires were successful in gathering people's thoughts on the design choices being made, but also favored a limited, intermittent form of engagement. The results are synthesized in principles for the successful integration of web-based technologies in future community design efforts: adaptability, fuji participation, nuanced participation and the need for links to the physical realm.
基金the National Natural Science Foundation of China(Nos.92051102,32200099,32225003 and 31970105)the Innovation Team Project of Universities in Guangdong Province(No.2020KCXTD023)the Shenzhen Science and Technology Program(JCYJ20200109105010363).
文摘Background:Synthetic microbial communities,with different strains brought together by balancing their nutrition and promoting their interactions,demonstrate great advantages for exploring complex performance of communities and for further biotechnology applications.The potential of such microbial communities has not been explored,due to our limited knowledge of the extremely complex microbial interactions that are involved in designing and controlling effective and stable communities.Results:Genome-scale metabolic models(GEM)have been demonstrated as an effective tool for predicting and guiding the investigation and design of microbial communities,since they can explicitly and efficiently predict the phenotype of organisms from their genotypic data and can be used to explore the molecular mechanisms of microbehabitats and microbe-microbe interactions.In this work,we reviewed two main categories of GEM-based approaches and three uses related to design of synthetic microbial communities:predicting multi-species interactions,exploring environmental impacts on microbial phenotypes,and optimizing community-level performance.Conclusions:Although at the infancy stage,GEM-based approaches exhibit an increasing scope of applications in designing synthetic microbial communities.Compared to other methods,especially the use of laboratory cultures,GEM-based approaches can greatly decrease the trial-and-error cost of various procedures for designing synthetic communities and improving their functionality,such as identifying community members,determining media composition,evaluating microbial interaction potential or selecting the best community configuration.Future efforts should be made to overcome the limitations of the approaches,ranging from quality control of GEM reconstructions to community-level modeling algorithms,so that more applications of GEMs in studying phenotypes of microbial communities can be expected.
文摘As urban renewal shifts to more routine community renewal, the design methods of community renewal are faced with new challenges. Considering the existing dilemma faced by old communities and based on the practice of community renewal of different scales in recent years, this paper proposes that the design for community renewal should consider not only the spatial structure of communities at the macro level, but also the needs of daily life at the micro level. It can help efficiently transform the existing space into public space that encourages residents’ participation and promote community vitality, to achieve a humanistic value beyond the physical environment.