Evaluation of the effectiveness of preventive nursing measures for pressure injuries in patients in the neurology intensive care unit

BACKGROUND Patients in neurology intensive care units(ICU)are prone to pressure injuries(PU)due to factors such as severe illness,long-term bed rest,and physiological dysfunction.PU not only causes pain and complications to patients,but also increases medical burden,prolongs hospitalization time,and affects the recovery process.AIM To evaluate and optimize the effectiveness of pressure injury prevention nursing measures in neurology ICU patients.METHODS A retrospective study was conducted,and 60 patients who were admitted to the ICU of the Department of Neurology were selected and divided into an observation group and a control group according to the order of admission,with 30 people in each group.The observation group implemented pressure injury prevention and nursing measures,while the control group adopted routine care.RESULTS Comparison between observation and control groups following pressure injury prevention nursing intervention revealed significantly lower incidence rates in the observation group compared to the control group at 48 h(8.3%vs 26.7%),7 d(16.7%vs 43.3%),and 14 d(20.0%vs 50.0%).This suggests a substantial reduction in pressure injury incidence in the observation group,with the gap widening over time.Additionally,patients in the observation group exhibited quicker recovery,with a shorter average time to get out of bed(48 h vs 72 h)and a shorter average length of stay(12 d vs 15 d)compared to the control group.Furthermore,post-intervention,patients in the observation group reported significantly improved quality of life scores,including higher scores in body satisfaction,feeling and function,and comfort(both psychological and physiological),indicating enhanced overall well-being and comfort following the implementation of pressure injury prevention nursing measures.CONCLUSION Implementing pressure injury preventive care measures for neurology ICU patients will have better results.

Comparative effectiveness research and health care reform in C hina

China has made significant progress in modernizing its healthcare system in the past 20 years. However, there are some issues that are difficult to solve on the current healthcare status, including the lack of medical care satisfaction in rural areas and urban areas, excessive consumption of medical resources, conflict and tension between the healthcare provider and patients, and the problems caused by the change of model of healthcare. Therefore, the State Council introduced the Opinions of the CPC Central Committee and the State Council on Deepening the Health Care System Reform in 2009 in order to provide basic, safe, effective, convenient and affordable healthcare for all residents. Despite the goals and policies set by the government, how to implement them remains to be challenging. Like evidence-based medicine, comparative effective research （ CER ） which started in the US in 2000 ＇s can provide diagnosis and treatment information for patients, doctors, and health policy makers to make decisions on the effective ways of caring for both individual and population. It also may apply to the conditions of healthcare reform in China. And there are opportunities and challenges of conducting CER in our country. We suggest that the government should establish the national-level CER research institute, CER Leadership Committee and relevant standards, fund the CER projects, and begin CER in certain disciplines.

The Defects and Future Research Direction of the Auditof the Policy Implementation Effect 2 China

近年来,政策执行效果审计在中国逐渐引起了关注.论文首先介绍了政策执行效果审计的内涵和研究的意义,在此基础上简要阐述了政策执行效果审计的发展现状,并指出了其缺陷,最后提出了未来的研究应重点关注建立政策执行效果审计理论框架体系、完善政策执行效果审计评价指标体系、探索对政策本身的评价以及将政策执行效果审计与新兴互联网工程及信息技术结合起来等几个方面.

Research Progress on Pharmacological Effects of Ardisia gigantifolia Stapf,a Traditional Chinese Medicine with Lingnan Characteristics

This paper comprehensively reviews the research progress on the pharmacological effects of Ardisia gigantifolia Stapf in recent years,and finds that Ardisia gigantifolia Stapf has good pharmacological effects in many aspects,including anti-inflammation,anti-oxidation,anti-thrombosis,anti-tumor and so on.In particular,more than ten saponins have been found to have good anti-tumor activity and have potential research value,which can provide reference for the full development and utilization of Ardisia gigantifolia Stapf resources.

On the Effectiveness of Group Work in English Language Teaching

This is a case research on group work and the aim is to investigate the effectiveness of group work in English teaching in English major of Zhejiang Guangsha College of Applied Construction Technology(ZGC).By carrying out a 15-week experiment on 08 Applied English Class 1 and 2,questionnaires on 08 Business English Class 1-5(213 students),and interviews on 22 teachers of English major,the research results show and prove that group work is often performed in ZGC and group work is quite effective in English teaching.

EXPERIMENTAL RESEARCH ON THE ANTI-CANCER IMMUNOMODULA-TIVE EFFECT OF THE POLYSOCOHARIBE-PEPTIDE OF CORIOLUS VERSICOLOR

Polysocoharibe-peptide of Coriolus Versicolor (PSP) is a new anti-cancer immunomodulative drug. The present paper reports on the experimental research done with this drug. It was found that PSP had the ability to recover hemolysin HC50, to increase the weight of the thymus, and increase the alexin of serum C3 and the IgG content of tumor bearing mice. FSP also significantly raised the pha-gocytic activity of macrophages in normal mice. PSP had a significant inhibitory effect on P38S and S180 cells. At the concentration of 1 mg/ml, PSP inhibited the proliferating activity of some human tumor call lines, such as SGC 7901, SPC, SLY and Mei. It had a direct toxic effect on SPC cells. PSP significantly inhibited the synthesis of nucleic acids of Ehrlich ascites carcinoma cells. In addition, PSP was antagonistic to the side effects of chemotherapy and radiotherapy.

Confounding Effect in Clinical Research of Otolaryngology and Its Control

Confounding effect is a critical issue in clinical research of otolaryngology because it can distort the research's conclusion. In this review, we introduce the definition of confounding effect, the methods of verifying and controlling the effect. Confounding effect can be prevented by research's design, and adjusted by data analysis. Clinicians would be aware and cautious about confounding effect in their research. They would be able to set up a research's design in which appropriate methods have been applied to prevent this effect.They would know how to adjust confounding effect after data collection. It is important to remember that sometimes it is impossible to eliminate confounding effect completely, and statistical method is not a master key. Solid research knowledge and critical thinking of our brain are the most important in controlling confounding effect.

Research funding and citations in papers of Nobel Laureates in Physics, Chemistry and Medicine, 2019-2020

Purpose:The goal of this study is a comparative analysis of the relation between funding(a main driver for scientific research)and citations in papers of Nobel Laureates in physics,chemistry and medicine over 2019-2020 and the same relation in these research fields as a whole.Design/methodology/approach:This study utilizes a power law model to explore the relationship between research funding and citations of related papers.The study here analyzes 3,539 recorded documents by Nobel Laureates in physics,chemistry and medicine and a broader dataset of 183,016 documents related to the fields of physics,medicine,and chemistry recorded in the Web of Science database.Findings:Results reveal that in chemistry and medicine,funded researches published in papers of Nobel Laureates have higher citations than unfunded studies published in articles;vice versa high citations of Nobel Laureates in physics are for unfunded studies published in papers.Instead,when overall data of publications and citations in physics,chemistry and medicine are analyzed,all papers based on funded researches show higher citations than unfunded ones.Originality/value:Results clarify the driving role of research funding for science diffusion that are systematized in general properties:a)articles concerning funded researches receive more citations than(un)funded studies published in papers of physics,chemistry and medicine sciences,generating a high Matthew effect(a higher growth of citations with the increase in the number of papers);b)research funding increases the citations of articles in fields oriented to applied research(e.g.,chemistry and medicine)more than fields oriented towards basic research(e.g.,physics).Practical implications:The results here explain some characteristics of scientific development and diffusion,highlighting the critical role of research funding in fostering citations and the expansion of scientific knowledge.This finding can support decision-making of policymakers and R&D managers to improve the effectiveness in allocating financial resources in science policies to generate a higher positive scientific and societal impact.

Facilitating faster and more effective research discovery

Wiley Open Access journals are supported by a network of authoritative journals and societies as well as internationally renowned editorial board members.All research articles published in Wiley Open Access journals are immediately freely available to read,download and share.Wiley Open Access journals are a group of high-quality open access journals offering authors a great venue to publish their work.

General laws of funding for scientific citations:how citations change in funded and unfunded research between basic and applied sciences

Purpose:The goal of this study is to analyze the relationship between funded and unfunded papers and their citations in both basic and applied sciences.Design/methodology/approach:A power law model analyzes the relationship between research funding and citations of papers using 831,337 documents recorded in the Web of Science database.Findings:The original results reveal general characteristics of the diffusion of science in research fields:a)Funded articles receive higher citations compared to unfunded papers in journals;b)Funded articles exhibit a super-linear growth in citations,surpassing the increase seen in unfunded articles.This finding reveals a higher diffusion of scientific knowledge in funded articles.Moreover,c)funded articles in both basic and applied sciences demonstrate a similar expected change in citations,equivalent to about 1.23%,when the number of funded papers increases by 1%in journals.This result suggests,for the first time,that funding effect of scientific research is an invariant driver,irrespective of the nature of the basic or applied sciences.Originality/value:This evidence suggests empirical laws of funding for scientific citations that explain the importance of robust funding mechanisms for achieving impactful research outcomes in science and society.These findings here also highlight that funding for scientific research is a critical driving force in supporting citations and the dissemination of scientific knowledge in recorded documents in both basic and applied sciences.Practical implications:This comprehensive result provides a holistic view of the relationship between funding and citation performance in science to guide policymakers and R&D managers with science policies by directing funding to research in promoting the scientific development and higher diffusion of results for the progress of human society.

Henan Cultural Information Resources Sharing Project Persistent Effect Mechanism Research

In order to reduce east--west section area of “digital divider” in China, Ministry of Culture laun- ches the National Cultural Information Resources Sharing Project in the mid-west provinces, and the state finance gives certain funds subsidy in the project construction period. Embarks highly from strategy during construction plan chosen and operational system management, as while as union digital library to construct a persistent effect mechanism. With the principle of state guidance, enterprise operation and benefit farmers, expand culture industry within the provincial and safeguard Cultural Information Resources Sharing Project sustainable development's, then promotes the rural economy culture full scale development.

Advances in Research of Extraction Processes and Anti-aging Effect of Flavonoids in Traditional Chinese Medicines

Flavonoids are secondary metabolites in plants and possess extensive pharmacological activities.Flavonoids have remarkable effect in prevent anti-tumor and cancer,but flavonoids can't be synthesized directly in the body.According to the different properties and structures of flavonoids in Traditional Chinese medicines,different extraction methods should be selected.Besides,flavonoids have good anti-aging effects.Based on three theories of modern aging,the anti-aging effect of flavonoids was discussed.It is expected to provide a beneficial reference for further development and utilization of natural flavonoid resources.

The Assessment of Non-Linear Effects in Clinical Research

Background: Novel models for the assessment of non-linear data are being developed for the benefit of making better predictions from the data. Objective: To review traditional and modern models. Results, and Conclusions: 1) Logit and probit transformations are often successfully used to mimic a linear model. Logistic regression, Cox regression, Poisson regression, and Markow modeling are examples of logit transformation;2) Either the x- or y-axis or both of them can be logarithmically transformed. Also Box Cox transformation equations and ACE (alternating conditional expectations) or AVAS (additive and variance stabilization for regression) packages are simple empirical methods often successful for linearly remodeling of non-linear data;3) Data that are sinusoidal, can, generally, be successfully modeled using polynomial regression or Fourier analysis;4) For exponential patterns like plasma concentration time relationships exponential modeling with or without Laplace transformations is a possibility. Spline and Loess are computationally intensive modern methods, suitable for smoothing data patterns, if the data plot leaves you with no idea of the relationship between the y- and x-values. There are no statistical tests to assess the goodness of fit of these methods, but it is always better than that of traditional models.

Research progress on effective chemical constituents of Sijunzi Decoction and mechanism of prevention and treatment of digestive system diseases

Sijunzi Decoction,as one of the classic Chinese traditional prescriptions,has been used clinically by major physicians since the Song Dynasty.This article reviewed and sorted out the literature on the effective chemistry of Sijunzi Decoction and the mechanism of its prevention and treatment of digestive system diseases.At present,its effective chemical components are derived from the saponins and flavonoids in ginseng and licorice,and are effective for gastrointestinal mucosal injury diseases and malignant digestive system.Digestive system diseases such as tumors,functional gastrointestinal diseases,non-alcoholic fatty liver,acute liver injury,and liver failure show a multi-path,multi-target effect mechanism.This article reviews the effective chemical components and research of Sijunzi Decoction and the related mechanisms of prevention and treatment of digestive system diseases,and provides valuable clues for the follow-up research of Sijunzi Decoction.

Teaching Reform Path of Architecture Specialty under the Collaborative Education of “Production, Teaching and Research” and Its Application Effect

To break through the development bottleneck of architecture specialty,it should think about how to realize the high-quality cultivation of talents through the adjustment of teaching system.Reform path of architecture under the collaborative education of "production,teaching and research" and its application effect are systemically studied.By analyzing the relationship among production,teaching and scientific research,the essence of integration and mutual assistance among the three is analyzed.A series of teaching reforms are carried out on the reform principles of teaching content,setting principles of practice curriculum and implementation paths of practice curriculum in the theoretical and practical courses of architecture specialty.The purpose is to make the achievements of scientific research and production contribute to the development of teaching,so that the three sections of "production,teaching and research" form a benign interaction,mutual assistance and common promotion.This teaching system under the collaborative education of "production,teaching and research" is of positive significance to the cultivation of architectural talents’ innovative ability,practical ability and comprehensive ability.

Research progress of protective effect of traditional Chinese medicine on brain cells

Objective:To review the protective effect of traditional Chinese medicine(TCM)on brain cells.Methods:The domestic journals and literature are searched and reviewed,classifies them according to the mechanisms of TCM,summaries their protective effect on brain cells.Results:Some single medicine and prescriptions possess a variety of biological activity,and has a protective effect on brain cells.Conclusion:Some TCM possess a variety of biological activity and have a protective effect on brain cells,so there are broad prospects to develop and apply these TCM.

Exploring the Factors Influencing the Effectiveness of Employee Recognition:An Analysis of Recognition Practices in Chinese Businesses

This research investigated the existing employee recognition methods in Chinese businesses and assessed their effectiveness.An in-depth interview was conducted in a commercial bank and a telecommunication company in China.Data was collected from thirty managers who were asked to share their opinions on employee recognition effectiveness and then analyzed using the thematic analysis method.The findings indicate that an effective recognition scheme included increased job satisfaction,employee motivation,work performance,and employee commitment.Furthermore,it suggested that organizational culture,the various forms of recognition practices,awareness of giving recognition,communication,and managerial skills,can all influence recognition effectiveness.This study adds to the development of a theoretical model to help understand what makes employee recognition more effective and to clarify the value generated by effective recognition.It also contributes to the understanding of employee recognition in the Chinese workplace.Practically,this study gives recommendations to managers regarding how to better evaluate their employee recognition systems and how to improve their effectiveness.

Research review in the main chemical constituents and pharmacological effects of Daphne acutiloba Rehd

Daphne acutiloba Rehd., belonging to Daphne genus of Thymelaeaceae is an evergreen shrub mainly distributed in the west of China. The roots, stem barks, leaves and fruits of this plant had been used as folk medicines for the treatment of rheumatoid arthriths, apoplesia and stomachache ache. Daphne diterpenes and tieranes diterpenes, guaiacane type sesquiterpene, lignans, diflavane and flavonoids, sterides, aliphatics and phenols were isolated from Daphne acutiloba Rehd. Researches demonstrated that the main chemical constituents of D. acutiloba Rehd. have multiple activities and good development prospect. This paper is presented as a review centering on the main chemical constituents and pharmacological effects of D. acutiloba Rehd. for the further research and development of this plant.

Research review on the main chemical constituents and pharmacological effects of Elephantopus scaber L.

Elephantopus scaber L.belongs to Elephantopus plant of Compositae,is widely used as the common Chinese herbal medicine in folk.Phytochemical investigations of the E.scaber have resulted in the isolation of triterpennoids,sesquiterpene lactones,sesquiterpene phenols,steroids,flavones,anthraquinones,peptides,lipid compounds and aryl compounds.It possesses the effects of antibacterial,clearing away heat and detoxification,detumescence and diuresis,and is used for treating lung cancer,cervical cancer,liver cancer,nasopharyngeal cancer,breast cancer,anemia and diarrhea.The research progress in the chemical constituents ofE scaber and pharmacological effects are reviewed for better explore and utilize theE scaber resource.