Taking the process of treating coronavirus disease 2019(COVID-19)with Western medicine and traditional Chinese medicine(TCM)as the research object,this article compares the characteristics of Western medicine and TCM ...Taking the process of treating coronavirus disease 2019(COVID-19)with Western medicine and traditional Chinese medicine(TCM)as the research object,this article compares the characteristics of Western medicine and TCM from the perspectives of aetiology,pathogenesis,diagnosis,and treatment.Western medicine and TCM each has its own theoretical system.Each has its own exposition in explaining the etiology and pathogenesis of the disease,and each has its own characteristics and advantages in diagnosis and treatment.Integrating TCM and Western medicine can improve the effect of treatment by forming a coordinated traditional Chinese and Western medicine treatment method.展开更多
Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients. Methods: Through parallel control design, 49 SARS patients were obs...Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients. Methods: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc. , on the basis of 'Recommended Protocol for Infectious Atypical Pneumonia' (abbreviated as 'Recommended Protocol') issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in 'Special Science and Technological Action to Prevent and Treat SARS' (abbreviated as 'Special S-T Action'), issued by Ministry of Science and Technology, together with the same WM as those for the control group. Results: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively, P<0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference, P>0. 05;(3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (P<0. 05). Conclusion: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.展开更多
By conducting specific comparison on traditional Chinese and western cultural connotations,it can be summarized that the specific differences existing in the elements of traditional cultural connotations as well as th...By conducting specific comparison on traditional Chinese and western cultural connotations,it can be summarized that the specific differences existing in the elements of traditional cultural connotations as well as their impacts on the overall development of social cultures. Effective research and exploration processes could be further formed to propel the overall development of social cultures,so that the roles of traditional Chinese and western cultural connotations in inheriting and developing traditional cultures can be fully revealed.展开更多
Objective: In comparison with chemotherapy, to evaluate therapeutic effects on advanced pancreatic cancer treated by integrative Chinese and western medicine (ICWM) therapies. Methods: Based on the retrospective study...Objective: In comparison with chemotherapy, to evaluate therapeutic effects on advanced pancreatic cancer treated by integrative Chinese and western medicine (ICWM) therapies. Methods: Based on the retrospective study of 56 patients with advanced pancreatic cancer, life table was applied to the analysis of patients' survival rate and Xz test to the comparison of therapeutic response between ICWM and chemotherapy groups. Results: The results showed that 1-year survival rate in the ICWM group was 55. 37%±3.24%; 2-year survival rate 34. 61%±16. 31%; 3-year survival rate 25. 96%±24. 64%; 5-year survival rate 25. 96%±24.64%; and median survival period 16. 3 months. However 1-year survival rate in the chemotherapy group was 21. 95%±27. 54% ; 2-year survival rate 7. 31%±27. 54% ; 3-year survival rate 0 % ; and median survival period 7. 5 months. The therapeutic effects between two groups were significantly different (P=0. 004). Further analysis suggested that the reduction of cancer mass in the ICWM group was more than that in chemotherapy group (P=0.049) and the improvement of advanced pancreatic cancer related-symptoms better than that of chemotherapy group (P = 0. 002). Conclusion: The ICWM comprehensive therapy is of important value in the treatment of advanced pancreatic cancer.展开更多
Metastasis and recurrence of tumors is the chief cause of death for such patients. Therefore, researches on the mechanism of its metastasis, prevention and treatment are the focal points in the field of traditional Ch...Metastasis and recurrence of tumors is the chief cause of death for such patients. Therefore, researches on the mechanism of its metastasis, prevention and treatment are the focal points in the field of traditional Chinese medicine (TCM) and Western medicine (WM) at present. WM practitioners" study on tumor metastasis involved its occurrence and development including every detail and process, and now it even has developed into the molecular biological field. py is used as the main means, but the efficacy is not n treatment surgical operation and radio- chemotheratoo optimistic. In recent years, TOM, as part of the comprehensive therapy, has been gradually gaining attention of oncologists. Aimed at solving the difficult problems in metastasis of tumor, many TOM practitioners on the basis of syndrome differentiation have raised theories about the cause of tumor metastasis. On the basis of these theories, some TOM recipes against tumor metastasis have been developed to serve as an effective supplement to surgical operation, radio- and chemotherapy. The present article summarizes research results in recent years about the cause of formation of tumor and its metastasis by TOM and WM, so as to offer some theoretical clues to the study of tumors metastasis.展开更多
Object:Traditional Chinese medicine(TCM)has been taught widely in the both Eastern and Western world countries.This study compared the origin,student source,duration,and curriculum design of TCM higher education progr...Object:Traditional Chinese medicine(TCM)has been taught widely in the both Eastern and Western world countries.This study compared the origin,student source,duration,and curriculum design of TCM higher education programs in China and five Western countries.Method:We searched the Internet and the China National Knowledge Infrastructure(CNKI)database to gather relevant information.Result:All the six countries offer acupuncture and/or Chinese herbal medicine programs at universities and/or private schools.However,there are great large differences among them in the education of curriculum and TCM students enrollment and curriculum policies of TCM courses.Conclusions:There are large differences among their curriculum and enrollment policies.This comparison should provide information about the further development of international standards in TCM education.展开更多
General survey ofhypertension has beencarried out in our coun—try for three times.Thelast time was in 1999,with the result showingthat in our country theincidence of hyperten-sion among people over15 years old was11...General survey ofhypertension has beencarried out in our coun—try for three times.Thelast time was in 1999,with the result showingthat in our country theincidence of hyperten-sion among people over15 years old was11.26%.The incidencehas been raised by 25%展开更多
Objective: To evaluate the effectiveness of a comprehensive therapy of traditional Chinese medicine (TCM) in reducing the relapse and metastasis of stage Ⅱ and Ⅲ colorectal cancer based on conventional Western me...Objective: To evaluate the effectiveness of a comprehensive therapy of traditional Chinese medicine (TCM) in reducing the relapse and metastasis of stage Ⅱ and Ⅲ colorectal cancer based on conventional Western medicine (WM) therapy. Methods: Two hundred and twenty-two patients in total, diagnosed as stage Ⅱ and Ⅲ colorectal cancer from February 2000 to March 2006, were recruited from Xiyuan Hospital, China Academy of Chinese Medical Sciences and the General Hospital of Beijing Military Area. They were followed-up once every 3-6 months. Twenty cases dropped out from the cohort. The remaining 202 patients were all treated with routine WM treatment [including R0 radical operation, or chemotherapy or/and radiotherapy according to national comprehensive cancer network (NCCN) clinical guidelines]. These patients were assigned to two groups based on whether or not they were additionally treated with TCM comprehensive therapy (orally administered with a decoction according to syndrome differentiation, combined with a traditional patent drug over one year). Ninety-eight patients from Xiyuan Hospital were treated with WM and TCM (combined group), and 104 patients from the General Hospital of Beijing Military Area were treated with WM alone (WM group). The demographic data at baseline were comparable, including the operation times, age, sex, TNM staging, and pathological types. The patients were followed-up for one to five years. Up to now, there are 98, 98, 77, 64, and 47 patients with 1, 2, 3, 4, and 5 years of follow-up in the combined group, respectively; and 104, 104, 97, 81, and 55 patients in the WM group, respectively. The results of the 5-year follow-up of all the patients will be available in 2011. Results: The relapse/metastasis rate of 1-, 2-, 3-, 4-, and 5-year were 0 (0/98), 2.04% (2/98), 11.69% (9/77), 14.06% (9/64), and 21.28% (10/47) in the combined group, and were 4.80%(5/104), 16.35% (17/104), 21.65% (21/97), 25.93% (21/81), and 38.18%(21/55) in the WM group, respectively. A significant difference was found in the second year between the two groups (X^2=12.117, P = 0.000). Median relapse/metastasis time was 26.5 months in the combined group and 16.0 months in the WM group. Conclusion: The combined therapy of TCM and WM may have great clinical value and a potential for decreasing the relapse or metastasis rate in stage Ⅱ and Ⅲ colorectal cancer after conventional WM therapy.展开更多
Objective: To explore the mechanisms of integrated traditional Chinese and western medicine (TCM-WM) in treating sudden deafness. Methods: One hundred and forty-six patients suffered from sudden deafness were divided ...Objective: To explore the mechanisms of integrated traditional Chinese and western medicine (TCM-WM) in treating sudden deafness. Methods: One hundred and forty-six patients suffered from sudden deafness were divided into two groups, 64 cases in the treated group were treated with TCM-WM therapy and the other 82 cases treated with western medicine alone for control. Results: The total effective rate of the treated group was 92. 19 %, that of the control group was 75. 61 %. The difference between the two groups was significant, P < 0. 01. Conclusion: The TCM-WM therapy is very effective in treating sudden deafness. Its mechanism might be: (1) Decrease of the blood viscosity and increase of the red blood cell's tenacity, so that the blood stream could pass through unimpededly. (2) Decrease of the plasma TXA2 level and increase of the PGI2 level,to benefit the blood supply for inner ear. (3) Increase of the activity of SOD and clearing away the free radicals so as to reduce the damage to the inner ear.展开更多
To evaluate objectively the clinical effect and superiority of integrated traditional Chinese and western medicine (TCM-WM) in treating mid-late hepatocarcinoma.Methods: The 313 patients observed were divided randomly...To evaluate objectively the clinical effect and superiority of integrated traditional Chinese and western medicine (TCM-WM) in treating mid-late hepatocarcinoma.Methods: The 313 patients observed were divided randomly into 3 groups, Group Ⅰ, Ⅱ and Ⅲ, they were treated with protocol TACE, protocol PEI and comprehensive conservative therapy respectively. Each group was sub-divided into 2 sub-groups, sub-group A and B, and sub-group As was treated coordinately with different Chinese herbal medicine, Sisheng Decoction to sub-group ⅠA and ⅡA, and cinobufacin or norcantharidin to ⅢA respectively. And Chinese herbal medicine prescribed according to TCM Syndrome Differentiation was also given to all the sub-group As.Results: The integrated therapy showed significant effect in treating mid-late hepatocarcinoma, as it could improve significantly the clinical symptoms and signs, raise the quality of life and prolong the survival time in patients. When TCM-WM cooperated with TACE, it could alleviate the toxic effect and enhance the therapeutic effect of chemotherapy. There was statistical significant difference in clinical effect between the TCM-WM treated groups and the western medicine treated groups (P<0.05).Conclusion: TCM-WM therapy displays not only the action in enhancing the short-term therapeutic effect of treatment in treating mid-late hepatocarcinoma but also shows significant effect in enhancing long-term therapeutic effect and prolonging survival time in patients. It is worth further spreading.展开更多
Traditional Chinese medicine(TCM)has played an important role in the prevention and treatment of Coronavirus disease 2019(COVID-19)epidemic in China.The integration of Chinese and Western medicine is an important feat...Traditional Chinese medicine(TCM)has played an important role in the prevention and treatment of Coronavirus disease 2019(COVID-19)epidemic in China.The integration of Chinese and Western medicine is an important feature of Chinese COVID-19 prevention and treatment.According to a series of evidence-based studies,TCM can reduce the infection rate of severe acute respiratory syndrome coronavirus 2 in high-risk groups.For patients with mild and moderate forms of COVID-19,TCM can relieve the related signs and symptoms,shorten the period of nucleic-acid negative conversion,and reduce conversion rate to the severe form of the disease.For COVID-19 patients with severe and critical illnesses,TCM can improve inflammatory indicators and blood oxygen saturation,shorten the hospital stay,and reduce the mortality rate.During recovery,TCM can improve patients’symptoms,promote organ function recovery,boost the quality of patients’life,and reduce the nucleic-acid repositive conversion rate.A series of mechanism research studies revealed that capability of TCM to treat COVID-19 through antiviral and anti-inflammatory effects,immune regulation,and protection of organ function via a multicomponent,multitarget,and multipathway approach.展开更多
43 cases of heart failure due to diastolic insufficiency of the left ventricle were treated with TCM differential treatment as the treatment group, the total effective rate being 86.0%. Statistically significant duTer...43 cases of heart failure due to diastolic insufficiency of the left ventricle were treated with TCM differential treatment as the treatment group, the total effective rate being 86.0%. Statistically significant duTerence (P【 0.05) in the therapeutic effects was found between the treatment group and the control (25 cases) group. Improvement of the left ventricular diastole in the treatment group was more obvious than that of the control group (P【 0.01), while contractility of the left ventricle was also improved to a certain extent.展开更多
The impact of evidence-based medicine and clinical epidemiology on clinical research has contributed to the development of Chinese medicine in modem times over the past two decades.Many concepts and methods of modem s...The impact of evidence-based medicine and clinical epidemiology on clinical research has contributed to the development of Chinese medicine in modem times over the past two decades.Many concepts and methods of modem science and technology are emerging in Chinese medicine research,resulting in constant progress.Systematic reviews,randomized controlled trials and other advanced mathematic approaches and statistical analysis methods have brought reform to Chinese medicine.In this new era,Chinese medicine researchers have many opportunities and challenges.On the one hand,Chinese medicine researchers need to dedicate themselves to providing enough evidence to the world through rigorous studies,whilst on the other hand,they also need to keep up with the speed of modem medicine research.For example,recently,real world study,comparative effectiveness research,propensity score techniques and registry study have emerged.This article aims to inspire Chinese medicine researchers to explore new areas by introducing these new ideas and new techniques.展开更多
中药监管科学(Traditional Chinese Medicine Rugulatory Science)作为我国新兴的、亟待发展的中西医交叉融合科学,不仅是监管科学(Rugulatory Science)作为国际前沿科学在中药监管领域的全新应用场景,更是一种根植于传统中医药学土壤...中药监管科学(Traditional Chinese Medicine Rugulatory Science)作为我国新兴的、亟待发展的中西医交叉融合科学,不仅是监管科学(Rugulatory Science)作为国际前沿科学在中药监管领域的全新应用场景,更是一种根植于传统中医药学土壤的中西医融合研究新模式和原创性科学思维方式。中药监管科学具有融合科学(Convergence Science)的问题导向性、多学科交叉、覆盖创新价值链、多元主体协同参与等特点。发展中药监管科学意味着中药监管科技创新朝向融合科学发生根本性变革,将有助于探索建立既符合中医药特点,又体现中西医融通的中药审评审批体系,以期获得中国式现代化中药监管领域的重大科技突破。展开更多
基金2018 Shanghai Leading Talents Training ProgramShanghai Clinical Research Center for Acupuncture and Moxibustion Accelerating(No.20MC1920500)+1 种基金the Development of Chinese Medicine Three-Year Action Plan of Shanghai(No.ZY(2018-2020)-CCCX-2004-04)Clinical Key Specialty Construction Foundation of Shanghai(No.shslczdzk04701).
文摘Taking the process of treating coronavirus disease 2019(COVID-19)with Western medicine and traditional Chinese medicine(TCM)as the research object,this article compares the characteristics of Western medicine and TCM from the perspectives of aetiology,pathogenesis,diagnosis,and treatment.Western medicine and TCM each has its own theoretical system.Each has its own exposition in explaining the etiology and pathogenesis of the disease,and each has its own characteristics and advantages in diagnosis and treatment.Integrating TCM and Western medicine can improve the effect of treatment by forming a coordinated traditional Chinese and Western medicine treatment method.
基金The study is supporded by The Ministry of Science Technology of 863 Programme "The Developing the Key of Technique and Products for Preventing SARS" (No.2003AA208101)
文摘Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients. Methods: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc. , on the basis of 'Recommended Protocol for Infectious Atypical Pneumonia' (abbreviated as 'Recommended Protocol') issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in 'Special Science and Technological Action to Prevent and Treat SARS' (abbreviated as 'Special S-T Action'), issued by Ministry of Science and Technology, together with the same WM as those for the control group. Results: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively, P<0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference, P>0. 05;(3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (P<0. 05). Conclusion: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.
文摘By conducting specific comparison on traditional Chinese and western cultural connotations,it can be summarized that the specific differences existing in the elements of traditional cultural connotations as well as their impacts on the overall development of social cultures. Effective research and exploration processes could be further formed to propel the overall development of social cultures,so that the roles of traditional Chinese and western cultural connotations in inheriting and developing traditional cultures can be fully revealed.
文摘Objective: In comparison with chemotherapy, to evaluate therapeutic effects on advanced pancreatic cancer treated by integrative Chinese and western medicine (ICWM) therapies. Methods: Based on the retrospective study of 56 patients with advanced pancreatic cancer, life table was applied to the analysis of patients' survival rate and Xz test to the comparison of therapeutic response between ICWM and chemotherapy groups. Results: The results showed that 1-year survival rate in the ICWM group was 55. 37%±3.24%; 2-year survival rate 34. 61%±16. 31%; 3-year survival rate 25. 96%±24. 64%; 5-year survival rate 25. 96%±24.64%; and median survival period 16. 3 months. However 1-year survival rate in the chemotherapy group was 21. 95%±27. 54% ; 2-year survival rate 7. 31%±27. 54% ; 3-year survival rate 0 % ; and median survival period 7. 5 months. The therapeutic effects between two groups were significantly different (P=0. 004). Further analysis suggested that the reduction of cancer mass in the ICWM group was more than that in chemotherapy group (P=0.049) and the improvement of advanced pancreatic cancer related-symptoms better than that of chemotherapy group (P = 0. 002). Conclusion: The ICWM comprehensive therapy is of important value in the treatment of advanced pancreatic cancer.
文摘Metastasis and recurrence of tumors is the chief cause of death for such patients. Therefore, researches on the mechanism of its metastasis, prevention and treatment are the focal points in the field of traditional Chinese medicine (TCM) and Western medicine (WM) at present. WM practitioners" study on tumor metastasis involved its occurrence and development including every detail and process, and now it even has developed into the molecular biological field. py is used as the main means, but the efficacy is not n treatment surgical operation and radio- chemotheratoo optimistic. In recent years, TOM, as part of the comprehensive therapy, has been gradually gaining attention of oncologists. Aimed at solving the difficult problems in metastasis of tumor, many TOM practitioners on the basis of syndrome differentiation have raised theories about the cause of tumor metastasis. On the basis of these theories, some TOM recipes against tumor metastasis have been developed to serve as an effective supplement to surgical operation, radio- and chemotherapy. The present article summarizes research results in recent years about the cause of formation of tumor and its metastasis by TOM and WM, so as to offer some theoretical clues to the study of tumors metastasis.
基金the Innovative Research Team of Beijing University of Chinese Medicine(2011-CXTD-09)partially supported by the“Capacity Building Project for TCM Clinical Researchers”(Grant No.:201207007)from the State Administration of TCM in China.
文摘Object:Traditional Chinese medicine(TCM)has been taught widely in the both Eastern and Western world countries.This study compared the origin,student source,duration,and curriculum design of TCM higher education programs in China and five Western countries.Method:We searched the Internet and the China National Knowledge Infrastructure(CNKI)database to gather relevant information.Result:All the six countries offer acupuncture and/or Chinese herbal medicine programs at universities and/or private schools.However,there are great large differences among them in the education of curriculum and TCM students enrollment and curriculum policies of TCM courses.Conclusions:There are large differences among their curriculum and enrollment policies.This comparison should provide information about the further development of international standards in TCM education.
文摘General survey ofhypertension has beencarried out in our coun—try for three times.Thelast time was in 1999,with the result showingthat in our country theincidence of hyperten-sion among people over15 years old was11.26%.The incidencehas been raised by 25%
基金Supported by Norway National Evidence Based Medicine to Provide Financial Assistance Project(No.0221)
文摘Objective: To evaluate the effectiveness of a comprehensive therapy of traditional Chinese medicine (TCM) in reducing the relapse and metastasis of stage Ⅱ and Ⅲ colorectal cancer based on conventional Western medicine (WM) therapy. Methods: Two hundred and twenty-two patients in total, diagnosed as stage Ⅱ and Ⅲ colorectal cancer from February 2000 to March 2006, were recruited from Xiyuan Hospital, China Academy of Chinese Medical Sciences and the General Hospital of Beijing Military Area. They were followed-up once every 3-6 months. Twenty cases dropped out from the cohort. The remaining 202 patients were all treated with routine WM treatment [including R0 radical operation, or chemotherapy or/and radiotherapy according to national comprehensive cancer network (NCCN) clinical guidelines]. These patients were assigned to two groups based on whether or not they were additionally treated with TCM comprehensive therapy (orally administered with a decoction according to syndrome differentiation, combined with a traditional patent drug over one year). Ninety-eight patients from Xiyuan Hospital were treated with WM and TCM (combined group), and 104 patients from the General Hospital of Beijing Military Area were treated with WM alone (WM group). The demographic data at baseline were comparable, including the operation times, age, sex, TNM staging, and pathological types. The patients were followed-up for one to five years. Up to now, there are 98, 98, 77, 64, and 47 patients with 1, 2, 3, 4, and 5 years of follow-up in the combined group, respectively; and 104, 104, 97, 81, and 55 patients in the WM group, respectively. The results of the 5-year follow-up of all the patients will be available in 2011. Results: The relapse/metastasis rate of 1-, 2-, 3-, 4-, and 5-year were 0 (0/98), 2.04% (2/98), 11.69% (9/77), 14.06% (9/64), and 21.28% (10/47) in the combined group, and were 4.80%(5/104), 16.35% (17/104), 21.65% (21/97), 25.93% (21/81), and 38.18%(21/55) in the WM group, respectively. A significant difference was found in the second year between the two groups (X^2=12.117, P = 0.000). Median relapse/metastasis time was 26.5 months in the combined group and 16.0 months in the WM group. Conclusion: The combined therapy of TCM and WM may have great clinical value and a potential for decreasing the relapse or metastasis rate in stage Ⅱ and Ⅲ colorectal cancer after conventional WM therapy.
文摘Objective: To explore the mechanisms of integrated traditional Chinese and western medicine (TCM-WM) in treating sudden deafness. Methods: One hundred and forty-six patients suffered from sudden deafness were divided into two groups, 64 cases in the treated group were treated with TCM-WM therapy and the other 82 cases treated with western medicine alone for control. Results: The total effective rate of the treated group was 92. 19 %, that of the control group was 75. 61 %. The difference between the two groups was significant, P < 0. 01. Conclusion: The TCM-WM therapy is very effective in treating sudden deafness. Its mechanism might be: (1) Decrease of the blood viscosity and increase of the red blood cell's tenacity, so that the blood stream could pass through unimpededly. (2) Decrease of the plasma TXA2 level and increase of the PGI2 level,to benefit the blood supply for inner ear. (3) Increase of the activity of SOD and clearing away the free radicals so as to reduce the damage to the inner ear.
文摘To evaluate objectively the clinical effect and superiority of integrated traditional Chinese and western medicine (TCM-WM) in treating mid-late hepatocarcinoma.Methods: The 313 patients observed were divided randomly into 3 groups, Group Ⅰ, Ⅱ and Ⅲ, they were treated with protocol TACE, protocol PEI and comprehensive conservative therapy respectively. Each group was sub-divided into 2 sub-groups, sub-group A and B, and sub-group As was treated coordinately with different Chinese herbal medicine, Sisheng Decoction to sub-group ⅠA and ⅡA, and cinobufacin or norcantharidin to ⅢA respectively. And Chinese herbal medicine prescribed according to TCM Syndrome Differentiation was also given to all the sub-group As.Results: The integrated therapy showed significant effect in treating mid-late hepatocarcinoma, as it could improve significantly the clinical symptoms and signs, raise the quality of life and prolong the survival time in patients. When TCM-WM cooperated with TACE, it could alleviate the toxic effect and enhance the therapeutic effect of chemotherapy. There was statistical significant difference in clinical effect between the TCM-WM treated groups and the western medicine treated groups (P<0.05).Conclusion: TCM-WM therapy displays not only the action in enhancing the short-term therapeutic effect of treatment in treating mid-late hepatocarcinoma but also shows significant effect in enhancing long-term therapeutic effect and prolonging survival time in patients. It is worth further spreading.
基金supported by National Key Research and Development Han—ateatcgic International Science and Technology Innovation Cooperation Key Project“Ineernational Cooperation Research on the Mechanism of the Treatment of COVID-19 by Hanshiyi Formula”(No.2021YFE0201100)National Key Research and Development Plan—“Public Safety Risk Control and Emergency Technical Equipment”Key Project Special“Demonstration Research on New Drug Development of Sanhan Huashi Granules for the treatment of COVID-19”(No.2022YFC0868300).
文摘Traditional Chinese medicine(TCM)has played an important role in the prevention and treatment of Coronavirus disease 2019(COVID-19)epidemic in China.The integration of Chinese and Western medicine is an important feature of Chinese COVID-19 prevention and treatment.According to a series of evidence-based studies,TCM can reduce the infection rate of severe acute respiratory syndrome coronavirus 2 in high-risk groups.For patients with mild and moderate forms of COVID-19,TCM can relieve the related signs and symptoms,shorten the period of nucleic-acid negative conversion,and reduce conversion rate to the severe form of the disease.For COVID-19 patients with severe and critical illnesses,TCM can improve inflammatory indicators and blood oxygen saturation,shorten the hospital stay,and reduce the mortality rate.During recovery,TCM can improve patients’symptoms,promote organ function recovery,boost the quality of patients’life,and reduce the nucleic-acid repositive conversion rate.A series of mechanism research studies revealed that capability of TCM to treat COVID-19 through antiviral and anti-inflammatory effects,immune regulation,and protection of organ function via a multicomponent,multitarget,and multipathway approach.
文摘43 cases of heart failure due to diastolic insufficiency of the left ventricle were treated with TCM differential treatment as the treatment group, the total effective rate being 86.0%. Statistically significant duTerence (P【 0.05) in the therapeutic effects was found between the treatment group and the control (25 cases) group. Improvement of the left ventricular diastole in the treatment group was more obvious than that of the control group (P【 0.01), while contractility of the left ventricle was also improved to a certain extent.
基金Supported by National Natural Science Foundation of China(No.81202776)the Seventh-Science Foundation of China Academy of Chinese Medical Sciences(No.ZZ070817)the Sixth-Science Foundation of Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences(No.Z0215)
文摘The impact of evidence-based medicine and clinical epidemiology on clinical research has contributed to the development of Chinese medicine in modem times over the past two decades.Many concepts and methods of modem science and technology are emerging in Chinese medicine research,resulting in constant progress.Systematic reviews,randomized controlled trials and other advanced mathematic approaches and statistical analysis methods have brought reform to Chinese medicine.In this new era,Chinese medicine researchers have many opportunities and challenges.On the one hand,Chinese medicine researchers need to dedicate themselves to providing enough evidence to the world through rigorous studies,whilst on the other hand,they also need to keep up with the speed of modem medicine research.For example,recently,real world study,comparative effectiveness research,propensity score techniques and registry study have emerged.This article aims to inspire Chinese medicine researchers to explore new areas by introducing these new ideas and new techniques.
文摘中药监管科学(Traditional Chinese Medicine Rugulatory Science)作为我国新兴的、亟待发展的中西医交叉融合科学,不仅是监管科学(Rugulatory Science)作为国际前沿科学在中药监管领域的全新应用场景,更是一种根植于传统中医药学土壤的中西医融合研究新模式和原创性科学思维方式。中药监管科学具有融合科学(Convergence Science)的问题导向性、多学科交叉、覆盖创新价值链、多元主体协同参与等特点。发展中药监管科学意味着中药监管科技创新朝向融合科学发生根本性变革,将有助于探索建立既符合中医药特点,又体现中西医融通的中药审评审批体系,以期获得中国式现代化中药监管领域的重大科技突破。