Continuous-flow microchannels are widely employed for synthesizing various materials,including nanoparticles,polymers,and metal-organic frameworks(MOFs),to name a few.Microsystem technology allows precise control over...Continuous-flow microchannels are widely employed for synthesizing various materials,including nanoparticles,polymers,and metal-organic frameworks(MOFs),to name a few.Microsystem technology allows precise control over reaction parameters,resulting in purer,more uniform,and structurally stable products due to more effective mass transfer manipulation.However,continuous-flow synthesis processes may be accompanied by the emergence of spatial convective structures initiating convective flows.On the one hand,convection can accelerate reactions by intensifying mass transfer.On the other hand,it may lead to non-uniformity in the final product or defects,especially in MOF microcrystal synthesis.The ability to distinguish regions of convective and diffusive mass transfer may be the key to performing higher-quality reactions and obtaining purer products.In this study,we investigate,for the first time,the possibility of using the information complexity measure as a criterion for assessing the intensity of mass transfer in microchannels,considering both spatial and temporal non-uniformities of liquid’s distributions resulting from convection formation.We calculate the complexity using shearlet transform based on a local approach.In contrast to existing methods for calculating complexity,the shearlet transform based approach provides a more detailed representation of local heterogeneities.Our analysis involves experimental images illustrating the mixing process of two non-reactive liquids in a Y-type continuous-flow microchannel under conditions of double-diffusive convection formation.The obtained complexity fields characterize the mixing process and structure formation,revealing variations in mass transfer intensity along the microchannel.We compare the results with cases of liquid mixing via a pure diffusive mechanism.Upon analysis,it was revealed that the complexity measure exhibits sensitivity to variations in the type of mass transfer,establishing its feasibility as an indirect criterion for assessing mass transfer intensity.The method presented can extend beyond flow analysis,finding application in the controlling of microstructures of various materials(porosity,for instance)or surface defects in metals,optical systems and other materials that hold significant relevance in materials science and engineering.展开更多
For many continuous bio-medieal signals with both strong nonlinearity and non-stationarity, two criterions were proposed for their complexity estimation : (1) Only a short data set is enough for robust estimation; ...For many continuous bio-medieal signals with both strong nonlinearity and non-stationarity, two criterions were proposed for their complexity estimation : (1) Only a short data set is enough for robust estimation; (2) No over-coarse graining preproeessing, such as transferring the original signal into a binary time series, is needed. Co complexity measure proposed by us previously is one of such measures. However, it lacks the solid mathematical foundation and thus its use is limited. A modified version of this measure is proposed, and some important properties are proved rigorously. According to these properties, this measure can be considered as an index of randomness of time series in some senses, and thus also a quantitative index of complexity under the meaning of randomness finding complexity. Compared with other similar measures, this measure seems more suitable for estimating a large quantity of complexity measures for a given task, such as studying the dynamic variation of such measures in sliding windows of a long process, owing to its fast speed for estimation.展开更多
The complexities of multi-wing chaotic systems based on the modified Chen system and a multi-segment quadratic function are investigated by employing the statistical complexity measure (SCM) and the spectral entropy...The complexities of multi-wing chaotic systems based on the modified Chen system and a multi-segment quadratic function are investigated by employing the statistical complexity measure (SCM) and the spectral entropy (SE) algorithm. How to choose the parameters of the SCM and SE algorithms is discussed. The results show that the complexity of the multi-wing chaotic system does not increase as the number of wings increases, and it is consistent with the results of the Grassberger-Procaccia (GP) algorithm and the largest Lyapunov exponent (LLE) of the multi-wing chaotic system.展开更多
The detection of early gastric cancer that often develops asymptomatically is crucial for improving patient survival.The photodynamic diagnosis(PDD)of gastric cancer using 5-aminolevulinic acid/protoporphyrin IX(5-ALA...The detection of early gastric cancer that often develops asymptomatically is crucial for improving patient survival.The photodynamic diagnosis(PDD)of gastric cancer using 5-aminolevulinic acid/protoporphyrin IX(5-ALA/PpIX)has been reported in several studies.However,the selectivity of PDD of gastric tumor is poor with often false-positive results that require the development of new methods to improve PDD for early gastric cancer.Therefore,a measure of the complexity of gastric microcirculation(multi-scale entropy,MSE)and the detrendedfluctuation analysis(DFA)were applied as additional tools to detect early gastric cancer in rats.In this experimental study,we used our original model of metastatic adenocarcinoma in the stomach of a rat.To induce a gastric tumor,we used a long-term combination(for 9 months,which is 1/2 of the life of rats)of two natural factors,such as chronic stress(overpopulation being typical for modern cities)and the daily presence of nitrites in food and drinks,which are common ingredients added to processed meat andfish to help preserve food.Our results clearly show that both methods,namely,PDD using 5-ALA/PpIX and complexity/correlation analysis,can detect early gastric cancer,which was confirmed by histological analysis.Pre-cancerous areas in the stomach were detected as an intermediatefluorescent signal or MSE level between normal and malignant lesions of the stomach.However,in some cases,PDD with 5-ALA/PpIX produced a false-positivefluorescence of exogenousfluorophores due to its accumulation in benign and inflammatory areas of the mucosa.This fact indicates that the PDD itself is not sufficient for the correct diagnosis of gastric cancer,and the use of additional characteristics,e.g.,complexity measures or scaling exponents,can significantly improve the diagnostic accuracy of PDD of gastric cancer that should be confirmed in further clinical studies and applications.展开更多
<div style="text-align:justify;"> <span style="font-family:Verdana;">Three design principles are prominent in software development-encapsulation, data hiding, and separation of concerns...<div style="text-align:justify;"> <span style="font-family:Verdana;">Three design principles are prominent in software development-encapsulation, data hiding, and separation of concerns. These principles are used as subjective quality criteria for both procedural and object-oriented applications. The purpose of research is to quantify encapsulation, data hiding, and separation of concerns is quantified using cyclomatic-based metrics. As a result of this research, the derived design metrics, coefficient of encapsulation, coefficient of data hiding, and coefficient of separation of concerns, are defined and applied to production software indicating whether the software has low or high encapsulation, data hiding, and separation of concerns.</span> </div>展开更多
Let d μ=ψ d ν be a complex valued measure where ν is a non negative measure and ψ is a complex valued function which satisfies b + p or b + ∞∩a 1 condition. We prove some basic martingale i...Let d μ=ψ d ν be a complex valued measure where ν is a non negative measure and ψ is a complex valued function which satisfies b + p or b + ∞∩a 1 condition. We prove some basic martingale inequalities such as B G inequalities, weak ( p,p) and strong (p,p) type inequalities for Banach space valued martingale with respect to complex measure μ .展开更多
In this paper we study the solutions and stability of the generalized Wilson's functional equation fc f(xty)dtt(t) + fc f(xtσ(y))dtt(t) =2f(x)g(y), x,y C G, where G is a locally compact group, a is a ...In this paper we study the solutions and stability of the generalized Wilson's functional equation fc f(xty)dtt(t) + fc f(xtσ(y))dtt(t) =2f(x)g(y), x,y C G, where G is a locally compact group, a is a continuous involution of G and # is an idempotent complex measure with compact support and which is a-invariant. We show that ∫Gg(xty)dp(t) + fcg(xta(y))dp(t) = 2g(x)g(y) if f = 0 and fcf(t.)dp(t) =0, where [fcf(t.)dp(t)](x) = fc f(tx)dμ(t). We also study some stability theorems of that equation and we establish the stability on noncommutative groups of the classical Wilson's functional equation f(xy) + X(y)f(xa(y)) = 2f(x)g(y) x, y C G, where X is a unitary character of G.展开更多
The event-related desynchronization/synchronization(ERD/ERS) time courses of lower and upper alpha band rhythms during hand motor imagery are investigated respectively by Fourier Sectral Entropy (FSE) in this paper. B...The event-related desynchronization/synchronization(ERD/ERS) time courses of lower and upper alpha band rhythms during hand motor imagery are investigated respectively by Fourier Sectral Entropy (FSE) in this paper. By analyzing one group of BCI competition data, it was found that FSE within upper alpha band displays a pronounced increase and decrease over contralateral and ipsilateral brain areas respectively at the onset of hand motor imagery, which is corresponding to the antagonistic ERD/ERS patterns in previous studies. Different from the upper alpha activity pattern, FSE within lower alpha band displays a consistent increase over both two hemispheres hand representative areas. The preliminary results show that FSE could disclose the different behaviors of the upper and lower alpha band rhythms so that a new idea with the complexity measure is provided to characterize functional dissociation of lower and upper frequency alpha rhythms in relation to hand motor imagery.展开更多
The popular single-factor complexity measure cannot comprehensively reflect program complexity and the existing hybrid complexity measure cannot express the interactive behaviors of programs. To treat these problems, ...The popular single-factor complexity measure cannot comprehensively reflect program complexity and the existing hybrid complexity measure cannot express the interactive behaviors of programs. To treat these problems, in this paper, we propose a complexity measure based on program slicing(CMBPS). CMPBS not only can evaluate factors which affect program complexity such as the length of the program, control flow, data flow and data types of output variables, but also can give expression of the interactive relation between programs. And we also prove that CMBPS satisfies all of Weyuker properties. Compared with the popular complexity measures, CMBPS is a well-structured complexity measure.展开更多
The spreading of the quantum-mechanical probability distribution density of the three-dimensional system is quantitatively determined by means of the local information-theoretic quantity of the Shannon information and...The spreading of the quantum-mechanical probability distribution density of the three-dimensional system is quantitatively determined by means of the local information-theoretic quantity of the Shannon information and information energy in both position and momentum spaces. The complexity measure which is equivalent to Cramer–Rao uncertainty product is determined. We have obtained the information content stored, the concentration of quantum system and complexity measure numerically for n = 0, 1, 2 and 3 respectively.展开更多
Traction force microscopy(TFM)is one of the most successful and broadly-used force probing technologies to quantify the mechanical forces in living cells.The displacement recovery of the fluorescent beads within the g...Traction force microscopy(TFM)is one of the most successful and broadly-used force probing technologies to quantify the mechanical forces in living cells.The displacement recovery of the fluorescent beads within the gel substrate,which serve as the fiducial markers,is one of the key processes.The traditional methods of extracting beads displacements,such as PTV,PIV,and DIC,persistently suffer from mismatching and loss of high-frequency information while dealing with the complex deformation around the focal adhesions.However,this information is crucial for the further analysis since the cells mainly transmit the force to the extracellular surroundings through focal adhesions.In this paper,we introduced convolutional neural network(CNN)to solve the problem.We have generated the fluorescent images of the non-deformable fluorescent beads and the displacement fields with different spatial complexity to form the training dataset.Considering the special image feature of the fluorescent images and the deformation with high complexity,we have designed a customized network architecture called U-DICNet for the feature extraction and displacement estimation.The numerical simulation and real experiment show that U-DICNet outperforms the traditional methods(PTV,PIV,and DIC).Particularly,the proposed U-DICNet obtains a more reliable result for the analysis of the local complex deformation around the focal adhesions.展开更多
The grating fringe on the reference plane is broadened in the intersecting axis system because of oblique-angle projection. In order to solve this problem, we study the theoretical model of the temporal phase unwrappi...The grating fringe on the reference plane is broadened in the intersecting axis system because of oblique-angle projection. In order to solve this problem, we study the theoretical model of the temporal phase unwrapping method based on the fringe cycle correction. We also study the 3D shape measurement theoretical model of the larger complex objects after considering the coordinate deviation and lens distortion. Experimental results demonstrate that the fringe cycle on the reference plane can be corrected to a constant value, the lens distortion can be corrected, and 3D shape of larger complex objects can be accurately measured.展开更多
基金supported by the Ministry of Science and High Education of Russia(Theme No.368121031700169-1 of ICMM UrB RAS).
文摘Continuous-flow microchannels are widely employed for synthesizing various materials,including nanoparticles,polymers,and metal-organic frameworks(MOFs),to name a few.Microsystem technology allows precise control over reaction parameters,resulting in purer,more uniform,and structurally stable products due to more effective mass transfer manipulation.However,continuous-flow synthesis processes may be accompanied by the emergence of spatial convective structures initiating convective flows.On the one hand,convection can accelerate reactions by intensifying mass transfer.On the other hand,it may lead to non-uniformity in the final product or defects,especially in MOF microcrystal synthesis.The ability to distinguish regions of convective and diffusive mass transfer may be the key to performing higher-quality reactions and obtaining purer products.In this study,we investigate,for the first time,the possibility of using the information complexity measure as a criterion for assessing the intensity of mass transfer in microchannels,considering both spatial and temporal non-uniformities of liquid’s distributions resulting from convection formation.We calculate the complexity using shearlet transform based on a local approach.In contrast to existing methods for calculating complexity,the shearlet transform based approach provides a more detailed representation of local heterogeneities.Our analysis involves experimental images illustrating the mixing process of two non-reactive liquids in a Y-type continuous-flow microchannel under conditions of double-diffusive convection formation.The obtained complexity fields characterize the mixing process and structure formation,revealing variations in mass transfer intensity along the microchannel.We compare the results with cases of liquid mixing via a pure diffusive mechanism.Upon analysis,it was revealed that the complexity measure exhibits sensitivity to variations in the type of mass transfer,establishing its feasibility as an indirect criterion for assessing mass transfer intensity.The method presented can extend beyond flow analysis,finding application in the controlling of microstructures of various materials(porosity,for instance)or surface defects in metals,optical systems and other materials that hold significant relevance in materials science and engineering.
文摘For many continuous bio-medieal signals with both strong nonlinearity and non-stationarity, two criterions were proposed for their complexity estimation : (1) Only a short data set is enough for robust estimation; (2) No over-coarse graining preproeessing, such as transferring the original signal into a binary time series, is needed. Co complexity measure proposed by us previously is one of such measures. However, it lacks the solid mathematical foundation and thus its use is limited. A modified version of this measure is proposed, and some important properties are proved rigorously. According to these properties, this measure can be considered as an index of randomness of time series in some senses, and thus also a quantitative index of complexity under the meaning of randomness finding complexity. Compared with other similar measures, this measure seems more suitable for estimating a large quantity of complexity measures for a given task, such as studying the dynamic variation of such measures in sliding windows of a long process, owing to its fast speed for estimation.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 61161006 and 61073187)
文摘The complexities of multi-wing chaotic systems based on the modified Chen system and a multi-segment quadratic function are investigated by employing the statistical complexity measure (SCM) and the spectral entropy (SE) algorithm. How to choose the parameters of the SCM and SE algorithms is discussed. The results show that the complexity of the multi-wing chaotic system does not increase as the number of wings increases, and it is consistent with the results of the Grassberger-Procaccia (GP) algorithm and the largest Lyapunov exponent (LLE) of the multi-wing chaotic system.
基金This collaborative work was supported in the frames of Russian Science Foundation project#18-15-00139\Optical technologies for early diagnostics of stomach cancer."Fluorescence measurements were made using spectrometric system purchased in the frames of Bulgarian NSF-MES project#DFNIB02/9/2014\Development of biophotonics methods as a basis of oncology theranostics."。
文摘The detection of early gastric cancer that often develops asymptomatically is crucial for improving patient survival.The photodynamic diagnosis(PDD)of gastric cancer using 5-aminolevulinic acid/protoporphyrin IX(5-ALA/PpIX)has been reported in several studies.However,the selectivity of PDD of gastric tumor is poor with often false-positive results that require the development of new methods to improve PDD for early gastric cancer.Therefore,a measure of the complexity of gastric microcirculation(multi-scale entropy,MSE)and the detrendedfluctuation analysis(DFA)were applied as additional tools to detect early gastric cancer in rats.In this experimental study,we used our original model of metastatic adenocarcinoma in the stomach of a rat.To induce a gastric tumor,we used a long-term combination(for 9 months,which is 1/2 of the life of rats)of two natural factors,such as chronic stress(overpopulation being typical for modern cities)and the daily presence of nitrites in food and drinks,which are common ingredients added to processed meat andfish to help preserve food.Our results clearly show that both methods,namely,PDD using 5-ALA/PpIX and complexity/correlation analysis,can detect early gastric cancer,which was confirmed by histological analysis.Pre-cancerous areas in the stomach were detected as an intermediatefluorescent signal or MSE level between normal and malignant lesions of the stomach.However,in some cases,PDD with 5-ALA/PpIX produced a false-positivefluorescence of exogenousfluorophores due to its accumulation in benign and inflammatory areas of the mucosa.This fact indicates that the PDD itself is not sufficient for the correct diagnosis of gastric cancer,and the use of additional characteristics,e.g.,complexity measures or scaling exponents,can significantly improve the diagnostic accuracy of PDD of gastric cancer that should be confirmed in further clinical studies and applications.
文摘<div style="text-align:justify;"> <span style="font-family:Verdana;">Three design principles are prominent in software development-encapsulation, data hiding, and separation of concerns. These principles are used as subjective quality criteria for both procedural and object-oriented applications. The purpose of research is to quantify encapsulation, data hiding, and separation of concerns is quantified using cyclomatic-based metrics. As a result of this research, the derived design metrics, coefficient of encapsulation, coefficient of data hiding, and coefficient of separation of concerns, are defined and applied to production software indicating whether the software has low or high encapsulation, data hiding, and separation of concerns.</span> </div>
文摘Let d μ=ψ d ν be a complex valued measure where ν is a non negative measure and ψ is a complex valued function which satisfies b + p or b + ∞∩a 1 condition. We prove some basic martingale inequalities such as B G inequalities, weak ( p,p) and strong (p,p) type inequalities for Banach space valued martingale with respect to complex measure μ .
文摘In this paper we study the solutions and stability of the generalized Wilson's functional equation fc f(xty)dtt(t) + fc f(xtσ(y))dtt(t) =2f(x)g(y), x,y C G, where G is a locally compact group, a is a continuous involution of G and # is an idempotent complex measure with compact support and which is a-invariant. We show that ∫Gg(xty)dp(t) + fcg(xta(y))dp(t) = 2g(x)g(y) if f = 0 and fcf(t.)dp(t) =0, where [fcf(t.)dp(t)](x) = fc f(tx)dμ(t). We also study some stability theorems of that equation and we establish the stability on noncommutative groups of the classical Wilson's functional equation f(xy) + X(y)f(xa(y)) = 2f(x)g(y) x, y C G, where X is a unitary character of G.
基金National Natural Science Foundation of China (No.30370395and30670534)Chinese Post-doctoral Science Foundation (No.20070410380)
文摘The event-related desynchronization/synchronization(ERD/ERS) time courses of lower and upper alpha band rhythms during hand motor imagery are investigated respectively by Fourier Sectral Entropy (FSE) in this paper. By analyzing one group of BCI competition data, it was found that FSE within upper alpha band displays a pronounced increase and decrease over contralateral and ipsilateral brain areas respectively at the onset of hand motor imagery, which is corresponding to the antagonistic ERD/ERS patterns in previous studies. Different from the upper alpha activity pattern, FSE within lower alpha band displays a consistent increase over both two hemispheres hand representative areas. The preliminary results show that FSE could disclose the different behaviors of the upper and lower alpha band rhythms so that a new idea with the complexity measure is provided to characterize functional dissociation of lower and upper frequency alpha rhythms in relation to hand motor imagery.
基金Supported by the National High Technology Research and Development Program of China(863 Program)(2009AA01220)the National Natural Science Foundation of China(91118007)
文摘The popular single-factor complexity measure cannot comprehensively reflect program complexity and the existing hybrid complexity measure cannot express the interactive behaviors of programs. To treat these problems, in this paper, we propose a complexity measure based on program slicing(CMBPS). CMPBS not only can evaluate factors which affect program complexity such as the length of the program, control flow, data flow and data types of output variables, but also can give expression of the interactive relation between programs. And we also prove that CMBPS satisfies all of Weyuker properties. Compared with the popular complexity measures, CMBPS is a well-structured complexity measure.
文摘The spreading of the quantum-mechanical probability distribution density of the three-dimensional system is quantitatively determined by means of the local information-theoretic quantity of the Shannon information and information energy in both position and momentum spaces. The complexity measure which is equivalent to Cramer–Rao uncertainty product is determined. We have obtained the information content stored, the concentration of quantum system and complexity measure numerically for n = 0, 1, 2 and 3 respectively.
基金supported by the National Natural Science Foundation of China(Grant Nos.11872354,11627803,and 12102423)the National Science and Technology Major Project(Grant No.J2019-V-0006-0100)。
文摘Traction force microscopy(TFM)is one of the most successful and broadly-used force probing technologies to quantify the mechanical forces in living cells.The displacement recovery of the fluorescent beads within the gel substrate,which serve as the fiducial markers,is one of the key processes.The traditional methods of extracting beads displacements,such as PTV,PIV,and DIC,persistently suffer from mismatching and loss of high-frequency information while dealing with the complex deformation around the focal adhesions.However,this information is crucial for the further analysis since the cells mainly transmit the force to the extracellular surroundings through focal adhesions.In this paper,we introduced convolutional neural network(CNN)to solve the problem.We have generated the fluorescent images of the non-deformable fluorescent beads and the displacement fields with different spatial complexity to form the training dataset.Considering the special image feature of the fluorescent images and the deformation with high complexity,we have designed a customized network architecture called U-DICNet for the feature extraction and displacement estimation.The numerical simulation and real experiment show that U-DICNet outperforms the traditional methods(PTV,PIV,and DIC).Particularly,the proposed U-DICNet obtains a more reliable result for the analysis of the local complex deformation around the focal adhesions.
基金supported by the National Natural Science Foundation of China(No.51365045)the Natural Science Foundation of Jiangxi Province(No.20122BAB202012)+1 种基金the Aviation Science Fund(No.2013ZE56013)the Education Department of Jiangxi Province(No.GJJ13522)
文摘The grating fringe on the reference plane is broadened in the intersecting axis system because of oblique-angle projection. In order to solve this problem, we study the theoretical model of the temporal phase unwrapping method based on the fringe cycle correction. We also study the 3D shape measurement theoretical model of the larger complex objects after considering the coordinate deviation and lens distortion. Experimental results demonstrate that the fringe cycle on the reference plane can be corrected to a constant value, the lens distortion can be corrected, and 3D shape of larger complex objects can be accurately measured.