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Breeding design in wheat by combining the QTL information in a GWAS panel with a general genetic map and computer simulation
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作者 Xiaobo Wang Weiwei Mao +5 位作者 Yongfa Wang Hongyao Lou Panfeng Guan Yongming Chen Huiru Peng Jiankang Wang 《The Crop Journal》 SCIE CSCD 2023年第6期1816-1827,共12页
A large amount of genome-wide association study(GWAS)panels together with quantitative-trait locus(QTL)information associated with breeding-targeted traits have been described in wheat(Triticum aestivum L.).However,th... A large amount of genome-wide association study(GWAS)panels together with quantitative-trait locus(QTL)information associated with breeding-targeted traits have been described in wheat(Triticum aestivum L.).However,the application of mapping results from a GWAS panel to conventional wheat breeding remains a challenge.In this study,we first report a general genetic map which was constructed from 44 published linkage maps.It permits the estimation of genetic distances between any two genetic loci with physical map positions,thereby unifying the linkage relationships between QTL,genes,and genomic markers from multiple genetic populations.Second,we describe QTL mapping in a wheat GWAS panel of 688 accessions,identifying 77 QTL associated with 12 yield and grain-quality traits.Because these QTL have known physical map positions,they could be mapped onto the general map.Finally,we present a design approach to wheat breeding by using known QTL information and computer simulation.Potential crosses between parents in the GWAS panel may be evaluated by the relative frequency of the target genotype,trait correlations in simulated progeny populations,and genetic gain of selected progenies.It is possible to simultaneously improve yield and grain quality by suitable parental selection,progeny population size,and progeny selection scheme.Applying the design approach will allow identifying the most promising crosses and selection schemes in advance of the field experiment,increasing predictability and efficiency in wheat breeding. 展开更多
关键词 Wheat breeding Breeding design GWAS panel General genetic map Computer simulation
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Cosserat Dynamic Modeling and Simulation of Mobile Cable on Satellite
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作者 Ziquan Wang Jinzhu Li +4 位作者 Weinan Chen Xuefeng Gao You Lü Leijie Shen Haojie Chen 《Journal of Beijing Institute of Technology》 EI CAS 2023年第6期740-753,共14页
Mainly for the problems that the configuration of the mobile cable on the satellite is very easy to change,the motion trajectory and dynamic characteristics of the cable can not be accu-rately predicted,which affects ... Mainly for the problems that the configuration of the mobile cable on the satellite is very easy to change,the motion trajectory and dynamic characteristics of the cable can not be accu-rately predicted,which affects the laying quality seriously,the dynamic modeling and simulation of mobile cable on the satellite are carried out.On the basis of referring to the previous papers,the existing mathematical model is improved.The equations of the base vector of the cable section principal axis coordinate system with respect to the arc coordinate s,the distribution force of cable balance equation,the matrix expression of the base vector after the rotation motion transformation in the section principal axis coordinate system,the angular velocity of cable,the section elastic strain and velocity calculation equations are given,and the Cosserat dynamic modeling of the mobile cable is established.Finally,the dynamic simulation model of the mobile cable assembly of the kinematic mechanism is established,and the changes of the force and torque on the cable con-straint end are obtained,which provides a reference for the dynamic modeling and simulation of the mobile cable on satellite. 展开更多
关键词 flexible cable large deformation curve geometry Cosserat modeling computer simulation
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Simulation of Crack Pattern Formation Due to Shrinkage in a Drying Material
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作者 Takuya Uehara 《Open Journal of Modelling and Simulation》 2023年第1期1-13,共13页
Crack patterns observed in nature have attracted the interest of researchers in various fields, and the mechanism of the pattern formation has been investigated. However, the phenomenon is very complicated, and many f... Crack patterns observed in nature have attracted the interest of researchers in various fields, and the mechanism of the pattern formation has been investigated. However, the phenomenon is very complicated, and many factors affect the process. Therefore, we are motivated to construct a general simulation code with a simple algorithm. In this study, crack pattern formation due to shrinkage caused by the drying of a wet material was simulated. The process was simplified as follows: tensile force is generated in the model, and a crack is generated when the tension exceeds a critical value. The tensile forces in the x and y directions are independently evaluated. A crack propagates perpendicular to the tension until it reaches another crack or a boundary. Based on this modeling, simulations with a two-dimensional square domain were performed. Consequently, a cross-divided pattern was generated. Assuming zigzag crack propagation, more realistic patterns were obtained. The effects of the boundary and domain size were also considered, and various characteristic patterns were obtained. Furthermore, the orientation dependency was simulated, and 45&#730 declined patterns and rectangularly divided patterns were generated. The model presented in this study is very simplified and is expected to be applicable to various objects. 展开更多
关键词 Desiccation Crack Tensile Force Crack Initiation Crack Propagation Pattern Formation Computer simulation
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Phase-field simulations of forced flow effect on dendritic growth perpendicular to flow 被引量:4
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作者 王智平 王军伟 +2 位作者 朱昌盛 冯力 肖荣振 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2011年第3期612-617,共6页
The effect of supercooled melt forced laminar flow at low Reynolds Number on dendritic growth perpendicular to melt flow direction was investigated with the phase-field method by incorporating melt convection and ther... The effect of supercooled melt forced laminar flow at low Reynolds Number on dendritic growth perpendicular to melt flow direction was investigated with the phase-field method by incorporating melt convection and thermal noise under non-isothermal condition. By taking the dendritic growth of high pure succinonitrile (SCN) supercooled melt as an example, side-branching shape difference of melts with flow and without flow was analyzed. Relationships among supercooled melt inflow velocity, deflexion angle of dendritic arm and dendritic tip growth velocity were studied. Results show that the melt inflow velocity has few effects on the dendritic tip growth velocity. A formula of relationship between the velocity of the melt in front of primary dendritic tip and the dendritic growth time was deduced, and the calculated result was in quantitative agreement with the simulation result. 展开更多
关键词 phase-field method laminar flow dendritic growth computer simulation SOLIDIFICATION flow velocity
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Sheet Metal Forming Simulation and Its Application in Stamping Process of Automobile Panels 被引量:4
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作者 张扬 张连洪 +1 位作者 李双义 王洪志 《Transactions of Tianjin University》 EI CAS 2002年第4期269-272,共4页
The paper starts with a brief overview to the necessity of sheet metal forming simulation and the complexity of automobile panel forming, then leads to finite element analysis (FEA) which is a powerful simulation too... The paper starts with a brief overview to the necessity of sheet metal forming simulation and the complexity of automobile panel forming, then leads to finite element analysis (FEA) which is a powerful simulation tool for analyzing complex three-dimensional sheet metal forming problems. The theory and features of the dynamic explicit finite element methods are introduced and the available various commercial finite element method codes used for sheet metal forming simulation in the world are discussed,and the civil and international status quo of automobile panel simulation as well. The front door outer panel of one certain new automobile is regarded as one example that the dynamic explicit FEM code Dynaform is used for the simulation of the front door outer panel forming process. Process defects such as ruptures are predicted. The improving methods can be given according to the simulation results. Foreground of sheet metal forming simulation is outlined. 展开更多
关键词 finite element analysis dynamic explicit methods sheet metal forming finite element method codes automobile panel computer simulation APPLICATION
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MONTE CARLO SIMULATION OF RADIATION FIELD OPTIMIZATION FOR MEDICAL LINAC 被引量:2
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作者 赵洪斌 张新 +2 位作者 包尚联 黄斐增 李泉凤 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2010年第1期7-12,共6页
A method for designing an X-ray flatness filter for medical electron linac is developed. It is used in the optimization process in the electron beam radiation system. Monte Carlo simulation method is used and two exam... A method for designing an X-ray flatness filter for medical electron linac is developed. It is used in the optimization process in the electron beam radiation system. Monte Carlo simulation method is used and two examples of real radiation system optimization processes for China-made medical electron linac are provided: 15 MV X- ray system of BJ-20 linac, and 12 MeV electron system of BJ-14. Results are verified by using the traditional method. 展开更多
关键词 linear accelerators computer simulation and Monte Carlo methods radiation system optimization flatness filter design
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Phase-field simulation of forced flow effect on random preferred growth direction of multiple grains 被引量:1
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作者 王军伟 朱昌盛 +2 位作者 王智平 冯力 肖荣振 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2011年第7期1620-1626,共7页
The random distribution problem of dendrite preferred growth direction was settled by random grid method.This method was used to study the influence of forced laminar flow effect on multiple grains during solidificati... The random distribution problem of dendrite preferred growth direction was settled by random grid method.This method was used to study the influence of forced laminar flow effect on multiple grains during solidification.Taking high pure succinonitrile (SCN) undercooled melt as an example,the forced laminar flow effect on multiple grains was studied by phase-field model of single grain which coupled with flow equations at non-isothermal condition.The simulation results show that the random grid method can reasonably settle the problem of random distribution and is more effective.When the solid fraction is relatively low,melt particles flow around the downstream side of dendrite,and the flow velocity between two dendrite arms becomes high.At the stage of solidification time less than 1800Δt,every dendrite grows freely;the upstream dendrites are stronger than the downstream ones.The higher the melt flow rate,the higher the solid fraction.However,when the solid fraction is relatively high,the dendrite arm intertwins and only a little residual melt which is not encapsulated can flow;the solid fraction will gradually tend to equal to solid fraction of melt without flow. 展开更多
关键词 phase-field method multiple grains laminar flow preferred growth direction computer simulation SOLIDIFICATION flow velocity
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Application of the Computer Simulation Technique to Developing EFI Engine 被引量:1
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作者 张付军 赵长禄 +2 位作者 黄英 葛蕴珊 孙业保 《Journal of Beijing Institute of Technology》 EI CAS 2000年第2期205-210,共6页
The application of computer simulation technique to electronic controlled fuel injection(EFI) engine was studied to increase the development speed and improve the overall performance of the engine and car. On the bas... The application of computer simulation technique to electronic controlled fuel injection(EFI) engine was studied to increase the development speed and improve the overall performance of the engine and car. On the basis of an EFI system developed by ourselves, the simulation model of the initial control data and engine operation points during a driving cycle and the car performance pridiction model were established. This method was applied to a mini car. The experiment showed that the simulated control data has good accuracy; and the engine test points and car performances obtained by simulation are useful for the matching of EFI system with gasoline engine and the development speed is increased. 展开更多
关键词 computer simulation electronic-controlled fuel injection (EFI) gasoline engine
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COMPUTER SIMULATION OF GRAIN BOUNDARY SEGREGATION BEHAVIOR AND MECHANISMS OF STRENGTHENING OF Mg IN Ni-BASED SUPERALLOYS 被引量:2
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作者 陈国良 葛红林 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 1995年第2期108+84-91,共9页
This paper used EAM and static relaxation method to simulate the grain boundary segregation behavior of Mg in Ni-based superalloys. The results offer a better understanding in the strengthening mechanism of Mg additio... This paper used EAM and static relaxation method to simulate the grain boundary segregation behavior of Mg in Ni-based superalloys. The results offer a better understanding in the strengthening mechanism of Mg addition in superalloys. The segregation of Mg increases the grain boundary cohesive bond and the vacancy formation energy, and decreases the mobility of grain boundary dislocation. It results in the retardation of creep voids initiation and growth. 展开更多
关键词 Mg in Superalloys Grain boundary segregation SUPERALLOY computer simulation
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A VIDEO SPECTRUM SPLITTING ENCODING SCHEME BASED ON HUMAN VISION AND ITS COMPUTER SIMULATION
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作者 赵宇 李华 +1 位作者 俞斯乐 滕建辅 《Transactions of Tianjin University》 EI CAS 1995年第1期79+76-79,共5页
In this paper, a 3-D video encoding scheme suitable for digital TV/HDTV (high definition television) is studied through computer simulation. The encoding scheme is designed to provide a good match to human vision. Bas... In this paper, a 3-D video encoding scheme suitable for digital TV/HDTV (high definition television) is studied through computer simulation. The encoding scheme is designed to provide a good match to human vision. Basically, this involves transmission of low frequency luminance information at full frame rate for good motion rendition and transmission of high frequency luminance signal at reduced frame rate for good detail in static images. 展开更多
关键词 D video encoding discrete wavelet transform human vision computer simulation
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Simulation of Restraint System Performance upon the Occupant's Response During Impact
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作者 孙立清 林逸 孙逢春 《Journal of Beijing Institute of Technology》 EI CAS 1999年第2期96-102,共7页
Aim To study the influence of restraint system performance upon the occupant's response during impact, and provide a scientific base for occupant restraint system design. Methods \ In the light of basic th... Aim To study the influence of restraint system performance upon the occupant's response during impact, and provide a scientific base for occupant restraint system design. Methods \ In the light of basic theory of multibody system dynamics and impact dynamics on the basis of classical theory of impact, R W method is adopted to construct the vehicle occupant system model consisting of fourteen rigid bodies, thirty seven DOFs and slip joints for the simulation. A software named SVC3D(3 dimensional simulation of vehicle crash) is developed in the FORTRAN language. Results\ The results of simulation have a good coincidence with those of tests and the restraint system with low elongation webbing and equipped with pretensioner provides better restraint effect for the occupant. Conclusion\ The model of vehicle occupant multibody system and SVC3D are suitable for use. Occupant should be belted with low elongation webbing to a certain degree and occupant restraint system should be equipped with pretensioner. 展开更多
关键词 vehicle occupant multibody system model multibody system dynamics impact dynamics computer simulation vehicle passive safety
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Computer Simulation of Compensation Method for Infrared Focal Plane Array
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作者 康长赓 《Journal of Beijing Institute of Technology》 EI CAS 2000年第3期330-334,共5页
A major motivation for this work is to investigate a method of computer simulation for compensating fixed pattern noise of the infrared focal plane arrays. A mathematical model of the output signal of focal plane arra... A major motivation for this work is to investigate a method of computer simulation for compensating fixed pattern noise of the infrared focal plane arrays. A mathematical model of the output signal of focal plane array was established; a compensating algorithm utilizing reference source was derived and simulating programs were designed. The images of compensating process verify the influence of nonuniformity of responsibility and offset on fixed pattern noise. The result show that simulating method of investigating compensation technology for focal plane arrays is feasible, the generated images and methods can be used to the study of image recognition. 展开更多
关键词 computer simulation mathematical model infrared focal plane array fixed pattern noise NONUNIFORMITY COMPENSATION
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Formation mechanism and crystal simulation of Na_2O-doped calcium aluminate compounds 被引量:2
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作者 田勇攀 潘晓林 +1 位作者 于海燕 涂赣峰 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2016年第3期849-858,共10页
Calcium aluminate clinkers doped with Na2O were synthesized using analytically pure reagents CaCO3, Al2O3, SiO2 and Na2CO3. The effects of Na2O-doping on the formation mechanism of calcium aluminate compounds and the ... Calcium aluminate clinkers doped with Na2O were synthesized using analytically pure reagents CaCO3, Al2O3, SiO2 and Na2CO3. The effects of Na2O-doping on the formation mechanism of calcium aluminate compounds and the crystal property of 12CaO·7Al2O3 (C12A7) cell were studied. The results show that the minerals containing Na2O mainly include 2Na2O·3CaO·5Al2O3 and Na2O·Al2O3, when the Na2O content in clinkers is less than 4.26% (mass fraction). The rest of Na2O is mainly doped in 12CaO·7Al2O3, which results in the decrease of the crystallinity of 12CaO·7Al2O3. The crystallinity of 2Na2O·3CaO·5Al2O3 is also inversely proportional to the Na2O content in clinkers. The formation processes of 2Na2O·3CaO·5Al2O3 and 12CaO·7Al2O3 can be divided into two ways, which are the direct reactions of raw materials and the transformation of CaO·Al2O3, respectively. The simulation shows that the covalency of O-Na bond in Na2O-doped 12CaO·7Al2O3 cell is weaker than those of O-Ca and O-Al bonds. The free energy of the unit cell increases because of Na2O doping, which results in the improvement of chemical activity of 12CaO·7Al2O3. The leaching efficiency of Al2O3 in clinker is improved from 34.81% to 88.17% when the Na2O content in clinkers increases from 0 to 4.26%. 展开更多
关键词 calcium aluminate Na_2O-doping formation mechanism crystal structure SINTERING computer simulation
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Modeling, Simulation and Optimization of a Whole Industrial Catalytic Naphtha Reforming Process on Aspen Plus Platform 被引量:14
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作者 侯卫锋 苏宏业 +1 位作者 胡永有 褚健 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2006年第5期584-591,共8页
A new 18-lump kinetic model for naphtha catalytic reforming reactions is discussed. By developing this model as a user module, a whole industrial continuous catalytic reforming process is simulated on Aspen plus plat-... A new 18-lump kinetic model for naphtha catalytic reforming reactions is discussed. By developing this model as a user module, a whole industrial continuous catalytic reforming process is simulated on Aspen plus plat-form. The technique utilizes the strong databases, complete sets of modules, and flexible simulation tools of the Aspen plus system and retains the characteristics of the proposed kinetic model. The calculated results are in fair agreement with the actual operating data. Based on the model of the whole reforming process, the process is opti-mized and the optimization results are tested in the actual industrial unit for about two months. The test shows that the process profit increases about 1000yuan·h-1 averagely, which is close to the calculated result. 展开更多
关键词 catalytic reforming kinetic model Aspen plus computer simulation process optimization
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Simulation aided hot zone design for faster growth of CZ silicon mono crystals 被引量:14
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作者 CAO Jianwei GAO Yu +2 位作者 CHEN Ying ZHANG Guohu QIU Minxiu 《Rare Metals》 SCIE EI CAS CSCD 2011年第2期155-159,共5页
Computer simulation was used for optimizing a hot zone for Czochralski (CZ) silicon crystal growth. The heater structure and heat shield material were investigated. With this optimized hot zone, the temperature grad... Computer simulation was used for optimizing a hot zone for Czochralski (CZ) silicon crystal growth. The heater structure and heat shield material were investigated. With this optimized hot zone, the temperature gradient near the crystal/melt interface increased and the CZ crystal could be grown at a faster rate. It is a great contribution for saving power consumption. 展开更多
关键词 crystal growth SILICON computer simulation temperature gradient
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Study on Intelligent Control and 3D Real-time Distributed Animation Simulation for Super-maneuver Attack of the New Generation Fighter 被引量:8
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作者 黎明 姜长生 +1 位作者 叶文青 张立 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2001年第4期235-244,共10页
The super-maneuver flight performance has a very high tactical value, and the development of this tactical value has great significance. A discussion is devoted to the study of intelligent control methods and technolo... The super-maneuver flight performance has a very high tactical value, and the development of this tactical value has great significance. A discussion is devoted to the study of intelligent control methods and technologies of real-time distributed 3-dimensional animation simulation for the super-maneuverable attack of new generational fighter in this paper. A flight control system of super-maneuver is reconstructed by adopting three layers BP neural networks of number 3, and the fire/flight coupler is designed by introducing a fuzzy control rule whose universe of discourse and gain are regulated adaptively on the line. Furthermore, a new method of real-time distributed 3-dimensional animation simulation is put forward, and a real-time distributed 3-dimensional animation simulation tool platform is constructed in this paper. The simulation result is lifelike, perceivable directly and useful. 展开更多
关键词 ANIMATION Computer simulation Flight dynamics Fuzzy control Intelligent control MANEUVERABILITY Neural networks
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Digestion mechanism and crystal simulation of roasted low-grade high-sulfur bauxite 被引量:9
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作者 Hong-fei WU Chao-yi CHEN +4 位作者 Jun-qi LI Yuan-pei LAN Lin-zhu WANG Bian-li QUAN Hui-xin JIN 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第6期1662-1673,共12页
Low-grade high-sulfur bauxite was pretreated via suspension roasting and muffle furnace roasting to remove sulfur and enhance digestion properties.The results show that sulfur can be efficiently removed,and the alumin... Low-grade high-sulfur bauxite was pretreated via suspension roasting and muffle furnace roasting to remove sulfur and enhance digestion properties.The results show that sulfur can be efficiently removed,and the alumina digestion properties are significantly improved after suspension roasting.Under optimal conditions(t=70 min,T=280°C,w(CaO)=8%and Nk=245 g/L),the digestion ratios are 94.45%and 92.08%for the suspension-roasted and muffle-roasted ore,respectively,and the apparent activation energies are 63.26 and 64.24 kJ/mol,respectively.Two crystal models were established by Materials Studio based on the XRD patterns.The DFT simulation shows that the existing Al—O bands after suspension roasting can improve alumina digestion.The(104)and(113)planes of Al2O3 after suspension roasting are found to combine with NaOH more easily than those of Al2O3 treated in a muffle furnace. 展开更多
关键词 high-sulfur bauxite suspension roasting reaction kinetics digestion mechanism crystal structure computer simulation
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Multifractal Simulation of GeochemicalMap Patterns 被引量:10
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作者 Agterberg Frederik P Geological Survey of Canada, 601 Booth Street, Ottawa, K1A 0E8, Canada 《Journal of China University of Geosciences》 SCIE CSCD 2001年第1期31-39,共9页
Using a simple multifractal model based on the model De Wijs, various geochemical map patterns for element concentration values are being simulated. Each pattern is self-similar on the average in that a similar patter... Using a simple multifractal model based on the model De Wijs, various geochemical map patterns for element concentration values are being simulated. Each pattern is self-similar on the average in that a similar pattern can be derived by application of the multiplicative cascade model used to any small subarea on the pattern. In other experiments, the original, self-similar pattern is distorted by superimposing a 2-dimensional trend pattern and by mixing it with a constant concentration value model. It is investigated how such distortions change the multifractal spectrum estimated by means of the 3-step method of moments. Discrete and continuous frequency distribution models are derived for patterns that satisfy the model of De Wijs. These simulated patterns satisfy a discrete frequency distribution model that as upper bound has a continuous frequency distribution to which it approaches in form when the subdivisions of the multiplicative cascade model are repeated indefinitely. This limiting distribution is lognormal in the center and has Pareto tails. Potentially, this approach has important implications in mineral and oil resource evaluation. 展开更多
关键词 fractals MULTIFRACTALS model of De Wijs GEOCHEMISTRY map patterns computer simulation.
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Numerical simulation of temperature field in horizontal core-filling continuous casting for copper cladding aluminum rods 被引量:6
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作者 Ya-jun Su Xin-hua Liu +2 位作者 Yong-fu Wu Hai-you Huang Jian-xin Xie 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2013年第7期684-692,共9页
The steady-state temperature field of horizontal core-filling continuous casting (HCFC) for producing copper cladding aluminum rods was simulated by finite element method to investigate the effects of key processing... The steady-state temperature field of horizontal core-filling continuous casting (HCFC) for producing copper cladding aluminum rods was simulated by finite element method to investigate the effects of key processing parameters on the positions of solid-liquid interfaces (SLIs) of copper and aluminum. It is found that mandrel tube length and mean withdrawing speed have significant effects on the SLI positions of both copper and aluminum. Aluminum casting temperature (TAI) (1003-1123 K) and secondary cooling water flux (600-900 L.h-1) have little effect on the SLI of copper but cause the SLI of aluminum to move 2-4 mm. When TA1 is in a range of 1043-1123 K, the liquid aluminum can fill continuously into the pre-solidified copper tube. Based on the numerical simulation, reasonable processing parameters were determined. 展开更多
关键词 metal cladding copper ALUMINUM continuous casting INTERFACES computer simulation
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Dynamic Simulation of the Aircraft Environmental Control System 被引量:6
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作者 何君 赵竞全 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2001年第3期129-133,共5页
The dynamic research of aircraft environmental control system (ECS) is an important step in the advanced ECS design process. Based on the thermodynamics theory, mathematical models for the dynamic performance simulati... The dynamic research of aircraft environmental control system (ECS) is an important step in the advanced ECS design process. Based on the thermodynamics theory, mathematical models for the dynamic performance simulating of aircraft ECS were set up and an ECS simulation toolbox (ECS_1.0) was created with MATLAB language. It consists of main component modules (ducts, valves, heat exchangers, compressor, turbine, etc.). An aircraft environmental control system computer model was developed to assist engineers with the design and development of ECS dynamic optimization. An example simulating an existing ECS was given which shows the satisfactory effects. 展开更多
关键词 Aircraft engines Compressors Computer programming languages Computer simulation Control system analysis Heat exchangers Mathematical models OPTIMIZATION
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