Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to Ja...Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to January 2006, nerve conduction velocities and skin temperatures of 20 healthy students were tested with questionnaire investigation. The results show that the nerve conduction velocities as well as skin temperatures present an obvious decline trend in a continuous draught, and that the nerve conduction velocities and skin temperatures have a definite linear relationship. Draught velocity is an important factor in winter that affects body comfort, and the subjects are sensitive to air velocity.展开更多
Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in pa...Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in patients with moderate to severe cubital tunnel syndrome and to analyze prognostic factors, we retrospectively reviewed 62 patients（65 elbows） diagnosed with cubital tunnel syndrome who underwent anterior subcutaneous transposition. Preoperatively, the initial severity of the disease was evaluated using the Mc Gowan scale as modified by Goldberg： 18 patients（28%） had grade IIA neuropathy, 20（31%） had grade IIB, and 27（42%） had grade III. Postoperatively, according to the Wilson ＆ Krout criteria, treatment outcomes were excellent in 38 patients（58%）, good in 16（25%）, fair in 7（11%）, and poor in 4（6%）, with an excellent and good rate of 83%. A negative correlation was found between the preoperative Mc Gowan grade and the postoperative Wilson ＆ Krout score. The patients having fair and poor treatment outcomes had more advanced age, lower nerve conduction velocity, and lower action potential amplitude compared with those having excellent and good treatment outcomes. These results suggest that anterior subcutaneous transposition of the ulnar nerve is effective and safe for the treatment of moderate to severe cubital tunnel syndrome, and initial severity, advancing age, and electrophysiological parameters can affect treatment outcome.展开更多
The distribution of sensory symptoms in carpal tunnel syndrome is strongly dependent on the degree of electrophysiological dysfunction of the median nerve. The association between carpal tunnel syndrome and ulnar nerv...The distribution of sensory symptoms in carpal tunnel syndrome is strongly dependent on the degree of electrophysiological dysfunction of the median nerve. The association between carpal tunnel syndrome and ulnar nerve entrapment is still unclear. In this study, we measured ulnar nerve function in 82 patients with carpal tunnel syndrome. The patients were divided into group I with minimal carpal tunnel syndrome （n = 35） and group II with mild to moderate carpal tunnel syndrome （n = 47） according to electrophysiological data. Sixty-one age- and sex-matched subjects without carpal tunnel syndrome were used as a control group. There were no significant differences in ulnar sensory nerve peak latencies or conduction velocities from the 4th and 5th fingers between patients with carpal tunnel syndrome and the control group. The ulnar sensory nerve action potential amplitudes from the 4th and 5th fingers were lower in patients with carpal tunnel syndrome than in the control group. The ratios of the ulnar sensory nerve action potential amplitudes from the 4th and 5th fingers were almost the same in patients with carpal tunnel syndrome as in the control group. These findings indicate that in patients with minimal to moderate carpal tunnel syndrome, there is some electrophysiological evidence of traction on the adjacent ulnar nerve fibers. The findings do not indicate axonal degeneration of the ulnar nerve.展开更多
Objective:To study the correlation between serum homocysteine (Hcy) content and the changes in patients with type 2 diabetic peripheral neuropathy (DPN).Methods: The patients who were diagnosed with T2DM between March...Objective:To study the correlation between serum homocysteine (Hcy) content and the changes in patients with type 2 diabetic peripheral neuropathy (DPN).Methods: The patients who were diagnosed with T2DM between March 2015 and April 2018 in our hospital were chosen and divided into the DPN group combined with DPN and the T2DM group not combined with DPN;healthy volunteers were chosen as the control group. The serum contents of Hcy, folic acid (FA), vitamin B12 (VitB12), inflammation indexes and oxidation indexes as well as sensory nerve conduction velocity (SCV) in extremities were measured.Results:Serum Hcy, soluble vascular cell adhesion molecule-1 (sVCAM-1), interleukin-1β (IL-1β) and high mobility group B1 (HMGB1) contents of DPN group were significantly higher than those of T2DM group and control group while serum FA, VitB12, superoxide dismutase (SOD) and glutathione peroxidase (GSH) contents as well as median nerve, ulnar nerve, radial nerve, common peroneal nerve and tibial nerve SCV levels were significantly lower than those of T2DM group and control group;serum sVCAM-1, IL-1β and HMGB1 contents significantly increased while serum SOD and GSH contents as well as median nerve, ulnar nerve, radial nerve, common peroneal nerve and tibial nerve SCV levels significantly decreased in DPN group of patients with hyperhomocysteinemia.Conclusion: Serum Hcy content significantly increases in patients with DPN, and it can aggravate the nerve conduction function injury and activate the inflammatory and oxidative reaction.展开更多
基金Project(CSTC 2004AA7008) supported by the State I mportant Project of the Science and Technology
文摘Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to January 2006, nerve conduction velocities and skin temperatures of 20 healthy students were tested with questionnaire investigation. The results show that the nerve conduction velocities as well as skin temperatures present an obvious decline trend in a continuous draught, and that the nerve conduction velocities and skin temperatures have a definite linear relationship. Draught velocity is an important factor in winter that affects body comfort, and the subjects are sensitive to air velocity.
基金supported by grants from the National Program on Key Basic Research Project of China(973 Program),No.2014CB542200a grant from Innovation Program of Ministry of Education,No.IRT1201+1 种基金the National Natural Science Foundation of China,No.31271284,31171150,81171146,30971526,31100860,31040043,31371210Program for New Century Excellent Talents in University of Ministry of Education of China,No.BMU20110270
文摘Although several surgical procedures exist for treating cubital tunnel syndrome, the best surgical option remains controversial. To evaluate the efficacy of anterior subcutaneous transposition of the ulnar nerve in patients with moderate to severe cubital tunnel syndrome and to analyze prognostic factors, we retrospectively reviewed 62 patients（65 elbows） diagnosed with cubital tunnel syndrome who underwent anterior subcutaneous transposition. Preoperatively, the initial severity of the disease was evaluated using the Mc Gowan scale as modified by Goldberg： 18 patients（28%） had grade IIA neuropathy, 20（31%） had grade IIB, and 27（42%） had grade III. Postoperatively, according to the Wilson ＆ Krout criteria, treatment outcomes were excellent in 38 patients（58%）, good in 16（25%）, fair in 7（11%）, and poor in 4（6%）, with an excellent and good rate of 83%. A negative correlation was found between the preoperative Mc Gowan grade and the postoperative Wilson ＆ Krout score. The patients having fair and poor treatment outcomes had more advanced age, lower nerve conduction velocity, and lower action potential amplitude compared with those having excellent and good treatment outcomes. These results suggest that anterior subcutaneous transposition of the ulnar nerve is effective and safe for the treatment of moderate to severe cubital tunnel syndrome, and initial severity, advancing age, and electrophysiological parameters can affect treatment outcome.
文摘The distribution of sensory symptoms in carpal tunnel syndrome is strongly dependent on the degree of electrophysiological dysfunction of the median nerve. The association between carpal tunnel syndrome and ulnar nerve entrapment is still unclear. In this study, we measured ulnar nerve function in 82 patients with carpal tunnel syndrome. The patients were divided into group I with minimal carpal tunnel syndrome （n = 35） and group II with mild to moderate carpal tunnel syndrome （n = 47） according to electrophysiological data. Sixty-one age- and sex-matched subjects without carpal tunnel syndrome were used as a control group. There were no significant differences in ulnar sensory nerve peak latencies or conduction velocities from the 4th and 5th fingers between patients with carpal tunnel syndrome and the control group. The ulnar sensory nerve action potential amplitudes from the 4th and 5th fingers were lower in patients with carpal tunnel syndrome than in the control group. The ratios of the ulnar sensory nerve action potential amplitudes from the 4th and 5th fingers were almost the same in patients with carpal tunnel syndrome as in the control group. These findings indicate that in patients with minimal to moderate carpal tunnel syndrome, there is some electrophysiological evidence of traction on the adjacent ulnar nerve fibers. The findings do not indicate axonal degeneration of the ulnar nerve.
文摘Objective:To study the correlation between serum homocysteine (Hcy) content and the changes in patients with type 2 diabetic peripheral neuropathy (DPN).Methods: The patients who were diagnosed with T2DM between March 2015 and April 2018 in our hospital were chosen and divided into the DPN group combined with DPN and the T2DM group not combined with DPN;healthy volunteers were chosen as the control group. The serum contents of Hcy, folic acid (FA), vitamin B12 (VitB12), inflammation indexes and oxidation indexes as well as sensory nerve conduction velocity (SCV) in extremities were measured.Results:Serum Hcy, soluble vascular cell adhesion molecule-1 (sVCAM-1), interleukin-1β (IL-1β) and high mobility group B1 (HMGB1) contents of DPN group were significantly higher than those of T2DM group and control group while serum FA, VitB12, superoxide dismutase (SOD) and glutathione peroxidase (GSH) contents as well as median nerve, ulnar nerve, radial nerve, common peroneal nerve and tibial nerve SCV levels were significantly lower than those of T2DM group and control group;serum sVCAM-1, IL-1β and HMGB1 contents significantly increased while serum SOD and GSH contents as well as median nerve, ulnar nerve, radial nerve, common peroneal nerve and tibial nerve SCV levels significantly decreased in DPN group of patients with hyperhomocysteinemia.Conclusion: Serum Hcy content significantly increases in patients with DPN, and it can aggravate the nerve conduction function injury and activate the inflammatory and oxidative reaction.
