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Epidemic of Rabies and Effect of Its Vaccine against a Dog That Consecutively Attacked Ten People in One Day 被引量:1
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作者 GAO Li Dong ZHANG Hong +15 位作者 CAI Liang CHEN Bo Zhong JIANG Yong Lin LIU Yun Zhi LV Xin Jun YU Peng Cheng HU Shi Xiong LIU Fu Qiang LI Hao LI Ge Ying SHEN Xin Xin TAO Xiao Yan ZHANG Si Yu LIU Jia Hui TANG Qing LI Jun Hua 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2014年第1期60-64,共5页
On December 21, 20:10, a stray dog consecutively attacked 10 people in Lengshui Village, Ningyuan County, Yongzhou City, Hunan Province, China. The dog was killed by the local CDC staff and vicinity villager, its bra... On December 21, 20:10, a stray dog consecutively attacked 10 people in Lengshui Village, Ningyuan County, Yongzhou City, Hunan Province, China. The dog was killed by the local CDC staff and vicinity villager, its brain tissue sample was taken within 24 h. The epidemic focus was disinfected and the injured people received post exposure prophylaxis (PEP). Pathogens were detected in the tissue sample by the provincial CDC. The immunity and safety of rabies vaccine were assayed after PEP, the injured people were regularly followed up in the following 2 y and 6 mon. 展开更多
关键词 Epidemic of Rabies and Effect of Its Vaccine against a Dog That consecutively Attacked Ten People in One Day gene Figure PV PEP
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Effects of Consecutively Monocultured Rehmannia glutinosa L.on Diversity of Fungal Community in Rhizospheric Soil 被引量:19
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作者 ZHANG Zhong-yi LIN Wen-xiong +2 位作者 YANG Yan-hui CHEN Hui CHEN Xin-jian 《Agricultural Sciences in China》 CAS CSCD 2011年第9期1374-1384,共11页
Continuous monoculture problems, or replanting diseases, are one of the key factors affecting productivity and quality of Chinese medicinal plants. The underlying mechanism is still being explored. Most of the studies... Continuous monoculture problems, or replanting diseases, are one of the key factors affecting productivity and quality of Chinese medicinal plants. The underlying mechanism is still being explored. Most of the studies on continuous monoculture ofRehmannia glutinosa L. are focused on plant nutritional physiology, root exudate, and its autotoxieity. However, the changes in the diversity of microflora in the rhizosphere mediated by the continuous monoculture pattern have been remained unknown. In this study, terminal restriction fragment length polymorphism (T-RFLP) technique was used for fingerprinting fungal diversity in the rhizosphere soil sampled from the fields ofR. glutinosa monocultured for 1 and 2 yr. The results showed that the structure of fungal community in consecutively moncultured rhizosphere soil was different from that in control soil (no cropping soil), and varied with the consecutive monoeulture years (1 and 2 yr). The comprehensive evaluation index (D) of fungal community estimated by principal component analysis of fragment number, peak area, Shannon-Weiner index, and Margalef index was higher in 1 yr monoculture soil than that in 2 yr monoculture soil, suggesting that consecutive monoculture of R. glutinosa could be a causative agent to decrease the diversity of fungal community in the rhizosphere soil. 展开更多
关键词 BIODIVERSITY consecutive monoculture problem fungal community Rehmannia glutinosa rhizosphere soil T-RFLP
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Projecting Spring Consecutive Rainfall Events in the Three Gorges Reservoir Based on Triple-Nested Dynamical Downscaling 被引量:2
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作者 Yanxin ZHENG Shuanglin LI +2 位作者 Noel KEENLYSIDE Shengping HE Lingling SUO 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第8期1539-1558,共20页
Spring consecutive rainfall events(CREs) are key triggers of geological hazards in the Three Gorges Reservoir area(TGR), China. However, previous projections of CREs based on the direct outputs of global climate model... Spring consecutive rainfall events(CREs) are key triggers of geological hazards in the Three Gorges Reservoir area(TGR), China. However, previous projections of CREs based on the direct outputs of global climate models(GCMs) are subject to considerable uncertainties, largely caused by their coarse resolution. This study applies a triple-nested WRF(Weather Research and Forecasting) model dynamical downscaling, driven by a GCM, MIROC6(Model for Interdisciplinary Research on Climate, version 6), to improve the historical simulation and reduce the uncertainties in the future projection of CREs in the TGR. Results indicate that WRF has better performances in reproducing the observed rainfall in terms of the daily probability distribution, monthly evolution and duration of rainfall events, demonstrating the ability of WRF in simulating CREs. Thus, the triple-nested WRF is applied to project the future changes of CREs under the middle-of-the-road and fossil-fueled development scenarios. It is indicated that light and moderate rainfall and the duration of continuous rainfall spells will decrease in the TGR, leading to a decrease in the frequency of CREs. Meanwhile, the duration, rainfall amount, and intensity of CREs is projected to regional increase in the central-west TGR. These results are inconsistent with the raw projection of MIROC6. Observational diagnosis implies that CREs are mainly contributed by the vertical moisture advection. Such a synoptic contribution is captured well by WRF, which is not the case in MIROC6,indicating larger uncertainties in the CREs projected by MIROC6. 展开更多
关键词 triple-nested downscaling Three Gorges Reservoir area consecutive rainfall events geological hazards PROJECTION
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The Fusion of Temporal Sequence with Scene Priori Information in Deep Learning Object Recognition
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作者 Yongkang Cao Fengjun Liu +2 位作者 Xian Wang Wenyun Wang Zhaoxin Peng 《Open Journal of Applied Sciences》 2024年第9期2610-2627,共18页
For some important object recognition applications such as intelligent robots and unmanned driving, images are collected on a consecutive basis and associated among themselves, besides, the scenes have steady prior fe... For some important object recognition applications such as intelligent robots and unmanned driving, images are collected on a consecutive basis and associated among themselves, besides, the scenes have steady prior features. Yet existing technologies do not take full advantage of this information. In order to take object recognition further than existing algorithms in the above application, an object recognition method that fuses temporal sequence with scene priori information is proposed. This method first employs YOLOv3 as the basic algorithm to recognize objects in single-frame images, then the DeepSort algorithm to establish association among potential objects recognized in images of different moments, and finally the confidence fusion method and temporal boundary processing method designed herein to fuse, at the decision level, temporal sequence information with scene priori information. Experiments using public datasets and self-built industrial scene datasets show that due to the expansion of information sources, the quality of single-frame images has less impact on the recognition results, whereby the object recognition is greatly improved. It is presented herein as a widely applicable framework for the fusion of information under multiple classes. All the object recognition algorithms that output object class, location information and recognition confidence at the same time can be integrated into this information fusion framework to improve performance. 展开更多
关键词 Computer Vison Object Recognition Deep Learning Consecutive Scene Information Fusion
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Analysis of the Maximum Consecutive Precipitation Variation in Liaoning Artificial Precipitation Test Area
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作者 杨旭 高杰 +3 位作者 杨青 田广元 陈刚 胡伟 《Meteorological and Environmental Research》 CAS 2010年第9期46-47,96,共3页
According to the daily precipitation data in artificial precipitation season during May to September from 1961 to 2008 in Liaoning Province,the maximum consecutive precipitation in the artificial precipitation test ar... According to the daily precipitation data in artificial precipitation season during May to September from 1961 to 2008 in Liaoning Province,the maximum consecutive precipitation in the artificial precipitation test area is studied based on the maximum consecutive precipitation from May to September in 48 years.The results shows that the period of maximum consecutive precipitation in each month is different,and the variance trends of maximum consecutive precipitation in May,July,August and September are decreasing,while the variance trend of maximum consecutive precipitation in June is increasing. 展开更多
关键词 Artificial precipitation test area Maximum consecutive precipitation Variation analysis China
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国内近十年认知心理学视域下的交替传译研究综述
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作者 温菲 《黑龙江教育学院学报》 2017年第8期112-114,共3页
近些年,国内很多专家和学者从认知心理学的角度对交替传译进行了深入的研究和探讨,取得了很多让人深思,给人启发的研究成果。但是从整体上看,对理论的推测和研究偏多,实证和案例研究较少。因此,通过搜集近十年认知心理学视角下的交替传... 近些年,国内很多专家和学者从认知心理学的角度对交替传译进行了深入的研究和探讨,取得了很多让人深思,给人启发的研究成果。但是从整体上看,对理论的推测和研究偏多,实证和案例研究较少。因此,通过搜集近十年认知心理学视角下的交替传译的研究的文章100多篇,对各篇观点进行归纳和整理,希望为今后的交替传译的认知心理学研究提供一些新的思路和视角。 展开更多
关键词 交替传译(consecutive interpreting) 认知心理学 综述
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A “Green” Cyclohexanone Oxidation Route Catalyzed by Hollow Titanium Silicate Zeolite for Preparing ε-Caprolactone,6-Hydroxyhexanoic Acid and Adipic Acid 被引量:5
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作者 Xia Changjiu Zhu Bin +1 位作者 Lin Min Shu Xingtian 《China Petroleum Processing & Petrochemical Technology》 SCIE CAS 2012年第4期33-41,共9页
Hollow titanium silicalite (HTS) molecular sieve has been synthesized, and information on its structure, physico- chemical characterization, as well as surface property was investigated by a host of analytical metho... Hollow titanium silicalite (HTS) molecular sieve has been synthesized, and information on its structure, physico- chemical characterization, as well as surface property was investigated by a host of analytical methods, such as XRF, XRD, low-temperature N2 adsorption/desorption, TEM, FT-IR, UV-Vis, 29Si MAS NIVIR, and XPS techniques. The characterization results suggest that HTS zeolite has a special hollow crystal structure and its mesopore volume is larger than that of TS-1 zeolite. The titanium species in this zeolite are composed of the framework tetrahedral Ti (IV) ions and extra-framework octahedral Ti (IV) ions, which tend to disperse into its bulk phase. This zeolite material also has been applied to catalyze the cyclohexanone oxidation process, and the products are not completely consistent with those results obtained by using TS-1 zeolite, which might be caused by their difference in pore structure and pore volume, especially the mesopore volume. Cy- clohexanone oxidation catalyzed by HTS zeolite is a representative consecutive reaction, the main target products of which are e-caprolactone, 6-hydroxyhexanoic acid and adipic acid. The effect of H202/cyclohexanone mole ratio on the cyclohexa- none conversion, the total target product selectivity, the distribution of three target products selectivity and their variations along with reaction time is also researched and analyzed, which indicate that HTS zeolite shows a high performance for the Baeyer-Villiger reaction of cyclohexanone and catalytic oxidation of 6-hydroxyhexanoic acid under mild conditions, and the quantity of active surface titanium species as well as the pore structure and mesopore volume controlling the mass diffusion rate are the key factors determining the catalytic activity of HTS zeolite and product selectivity. 展开更多
关键词 catalytic oxidation CYCLOHEXANONE HTS zeolite Baeyer-Villiger reaction consecutive reaction
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Spatial and temporal patterns of drought in Zambia 被引量:3
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作者 Brigadier LIBANDA ZHENG Mie Chilekana NGONGA 《Journal of Arid Land》 SCIE CSCD 2019年第2期180-191,共12页
Drought acutely affects economic sectors, natural habitats and communities. Understanding the past spatial and temporal patterns of drought is crucial because it facilitates the forecasting of future drought occurrenc... Drought acutely affects economic sectors, natural habitats and communities. Understanding the past spatial and temporal patterns of drought is crucial because it facilitates the forecasting of future drought occurrences and informs decision-making processes for possible adaptive measures. This is especially important in view of a changing climate. This study employed the World Meteorological Organization(WMO)-recommended standardized precipitation index(SPI) to investigate the spatial and temporal patterns of drought in Zambia from 1960 to 2016. The relationship between the occurrence of consecutive dry days(CDD; consecutive days with less than 1 mm of precipitation) and SPI was also investigated. Horizontal wind vectors at 850 hPa during the core of the rainy season(December–February)were examined to ascertain the patterns of flow during years of extreme and severe drought; and these were contrasted with the patterns of flow in 2007, which was a generally wet year. Pressure vertical velocity was also investigated. Based on the gamma distribution, SPI successfully categorized extremely dry(with a SPI value less than or equal to –2.0) years over Zambia as 1992 and 2015, a severely dry(–1.9 to –1.5) year as 1995, moderately dry(–1.4 to –1.0) years as 1972, 1980, 1987, 1999 and 2005, and 26 near normal years(–0.9 to 0.9). The occurrence of CDD was found to be strongly negatively correlated with SPI with a coefficient of –0.6. Further results suggest that, during wet years, Zambia is influenced by a clockwise circulating low-pressure zone over the south-eastern Angola, a second such zone over the northern and eastern parts, and a third over the Indian Ocean. In stark contrast, years of drought were characterized by an anti-clockwise circulating high-pressure zone over the south-western parts of Zambia,constraining precipitation activities over the country. Further, wet years were characterized by negative pressure vertical velocity anomalies, signifying ascending motion; while drought years were dominated by positive anomalies, signifying descending motion, which suppresses precipitation. These patterns can be used to forecast drought over Zambia and aid in strategic planning to limit the potential damage of drought. 展开更多
关键词 standardized PRECIPITATION index patterns of DROUGHT consecutive DRY DAYS vertical velocity GAMMA distribution RAINFALL
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Modified consecutive modal pushover procedure for seismic investigation of one-way asymmetric-plan tall buildings 被引量:4
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作者 Faramarz Khoshnoudian Mahdi Kiani 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2012年第2期221-232,共12页
The effects of higher modes and torsion have a significant impact on the seismic responses of asymmetric-plan tall buildings. A consecutive modal pushover (CMP) procedure is one of the pushover methods that have been ... The effects of higher modes and torsion have a significant impact on the seismic responses of asymmetric-plan tall buildings. A consecutive modal pushover (CMP) procedure is one of the pushover methods that have been developed to consider these effects. The aim of this paper is to modify the (CMP) analysis procedure to estimate the seismic demands of one-way asymmetric-plan tall buildings with dual systems. An analysis of 10-, 15- and 20-story asymmetric-plan buildings is carried out, and the results from the modified consecutive modal pushover (MCMP) procedure are compared with those obtained from the modal pushover analysis (MPA) procedure and the nonlinear time history analysis (NLTHA). The MCMP estimates of the seismic demands of one-way asymmetric-plan buildings demonstrate a reasonable accuracy, compared to the results obtained from the NLTHA. Furthermore, the accuracy of the MCMP procedure in the prediction of plastic hinge rotations is better than the MPA procedure. The new pushover procedure is also more accurate than the FEMA load distribution and the MPA procedure. 展开更多
关键词 modified consecutive modal pushover seismic demands nonlinear time history analysis asymmetric-plan tall buildings TORSION
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Importance measure of system reliability upgrade for multi-state consecutive k-out-of-n systems 被引量:3
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作者 HonQvan Dui Shubin si Zhiqiang Cai Shudong Sun Yingfeng Zhang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2012年第6期936-942,共7页
Importance measures in reliability systems are used to identify weak components in contributing to a proper function of the system. Traditional importance measures mainly concerned the changing value of the system rel... Importance measures in reliability systems are used to identify weak components in contributing to a proper function of the system. Traditional importance measures mainly concerned the changing value of the system reliability caused by the change of the reliability of the component, and seldom considered the joint effect of the probability distribution, improvement rate of the object component. This paper studies the rate of the system reliability upgrading with an improvement of the component reliability for the multi-state consecutive k-out-of-n system. To verify the multi-state consecutive k-out-of-n system reliability upgrading by improving one component based on its improvement rate, an increasing potential importance (IPI) and its physical meaning are described at first. Secondly, the relationship between the IPI and Birnbaum importance measures are discussed. And the IPI for some different improvement actions of the component is further discussed. Thirdly, the characteristics of the IPI are analyzed. Finally, an application to an oil pipeline system is given. 展开更多
关键词 system reliability multi-state consecutive k-out-of-nsystem IMPROVEMENT Birnbaum importance.
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A Quantized Kernel Least Mean Square Scheme with Entropy-Guided Learning for Intelligent Data Analysis 被引量:5
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作者 Xiong Luo Jing Deng +3 位作者 Ji Liu Weiping Wang Xiaojuan Ban Jenq-Haur Wang 《China Communications》 SCIE CSCD 2017年第7期127-136,共10页
Quantized kernel least mean square(QKLMS) algorithm is an effective nonlinear adaptive online learning algorithm with good performance in constraining the growth of network size through the use of quantization for inp... Quantized kernel least mean square(QKLMS) algorithm is an effective nonlinear adaptive online learning algorithm with good performance in constraining the growth of network size through the use of quantization for input space. It can serve as a powerful tool to perform complex computing for network service and application. With the purpose of compressing the input to further improve learning performance, this article proposes a novel QKLMS with entropy-guided learning, called EQ-KLMS. Under the consecutive square entropy learning framework, the basic idea of entropy-guided learning technique is to measure the uncertainty of the input vectors used for QKLMS, and delete those data with larger uncertainty, which are insignificant or easy to cause learning errors. Then, the dataset is compressed. Consequently, by using square entropy, the learning performance of proposed EQ-KLMS is improved with high precision and low computational cost. The proposed EQ-KLMS is validated using a weather-related dataset, and the results demonstrate the desirable performance of our scheme. 展开更多
关键词 quantized kernel least mean square (QKLMS) consecutive square entropy data analysis
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Predictive Tracking Control of Network-Based Agents With Communication Delays 被引量:4
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作者 Tianyong Zhang Guoping Liu 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2018年第6期1150-1156,共7页
This paper investigates the remote tracking control problem of Network-based Agents with communication delays existing in both forward and feedback communication channels.A networked predictive tracking controller is ... This paper investigates the remote tracking control problem of Network-based Agents with communication delays existing in both forward and feedback communication channels.A networked predictive tracking controller is proposed to compensate the negative effects caused by bilateral time-delays in a wireless network. Furthermore, the problem of consecutive data loss in the feedback channel is solved using aforementioned controller, where lateral movement perturbations are introduced.Simulations and experiments are provided for several cases,which verify the realizability and effectiveness of the proposed controller. 展开更多
关键词 Consecutive data loss network-based agents networked predictive control remote tracking time-delay
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Study of the material removal mechanism of glass-ceramics based on consecutive incremental loading in ductile-regime grinding 被引量:2
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作者 Xue Li 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2020年第2期88-95,共8页
Glass-ceramics have many excellent properties and are widely used in various fields. During the grinding process,the workpiece surface is typically subject to material removal by grit of incremental heights, which has... Glass-ceramics have many excellent properties and are widely used in various fields. During the grinding process,the workpiece surface is typically subject to material removal by grit of incremental heights, which has rarely been the focus of research. As such, it is necessary to study the material removal mechanism of glass-ceramics under consecutive incremental loading, which more closely reflects the actual grinding process. In this paper,to analyze the plastic deformation and residual stress of lithium aluminosilicate(LAS) glass-ceramics, a finite element model is established based on the Drucker–Prager yield criterion for ductile regimes. A nano-scratch test was also conducted and the test results show that both the residual depth and residual stress increase with an increase in the number of increments, and that consecutive incremental loading promotes the plastic deformation of glass-ceramics and increases the residual stress of the material in the ductile-regime process. These findings provide guidance for achieving higher dimensional accuracy in the actual grinding of glass-ceramics parts. 展开更多
关键词 GRINDING GLASS-CERAMICS Scratch tests Material removal mechanism Consecutive incremental loading
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Clinical risk factors for the development of consecutive exotropia:a comparative clinical study 被引量:2
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作者 Hande Tayla Sekeroglu Kadriye Erkan Turan +2 位作者 Jale Karakaya Emin Cumhur Sener Ali Sefik Sanac 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2016年第6期886-889,共4页
AIM: To compare a group of patients with consecutive exotropia with patients who had ≤ 10 prism diopters (PD) esotropia or no deviation postoperatively in terms of probable clinical risk factors for the developmen... AIM: To compare a group of patients with consecutive exotropia with patients who had ≤ 10 prism diopters (PD) esotropia or no deviation postoperatively in terms of probable clinical risk factors for the development of consecutive exotropia. METHODS: The study recruited fourteen patients who developed consecutive exodeviation during follow-up period after the correction of esotropia who were categorized as group 1 and thirty-one patients who had still ≤10 PD esotropia or no deviation at the final visit that were considered as group 2. Clinical risk factors leading the development of consecutive deviation were analyzed as the main outcome measures. RESULTS: The mean age of patients was 4.57±3.11y in group 1 and 5.10±3.52y in group 2 (P=0.634). There was no significant difference of preoperative near and distant deviations among two groups (P =0.835, 0.928 respectively). The mean amount of medial rectus recession and lateral rectus resection was similar in both groups (P=0.412, 0.648 respectively). Convergence insufficiency and neurological diseases were more frequent in group 1 (P-0.007, 0.045). Accompanying neurological disease was found to be as a significant factor increasing the risk of the development of consecutive exotropia significantly [odds ratios (OR): 5.75 (1.04-31.93)]. CONCLUSION: Accompanying neurological disease appears to be a significant clinical risk factor for the development of consecutive exodeviation during postoperative follow-up after the correction of esotropia. However, larger studies are needed in order to interpret the results to the clinical practice and to ascertain other concurrent risk factors. 展开更多
关键词 consecutive exotropia ESOTROPIA medial rectus recession neurological disorder lateral rectus resection
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Selectivity modulation in the consecutive hydrogenation of benzaldehyde via functionalization of carbon nanotubes 被引量:2
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作者 Yonghua Zhou Jing Liu +2 位作者 Xingyun Li Xiulian Pan Xinhe Bao 《Journal of Natural Gas Chemistry》 EI CAS CSCD 2012年第3期241-245,共5页
Hydrogenation of benzaldehyde is a typical consecutive reaction, since the intermediate benzyl alcohol is apt to be further hydrogenated. Here we demonstrate that the selectivity of benzyl alcohol can be tuned via fun... Hydrogenation of benzaldehyde is a typical consecutive reaction, since the intermediate benzyl alcohol is apt to be further hydrogenated. Here we demonstrate that the selectivity of benzyl alcohol can be tuned via functionalization of carbon nanotubes (CNTs), which are used as the support of Pd. With the original CNTs, the selectivity of benzyl alcohol is 88% at a 100% conversion of benzaldehyde. With introduction of oxygen-containing groups onto CNTs, it drops to 27%. In contrast, doping CNTs with N atoms, the selectivity reaches 96% under the same reaction conditions. The kinetic study shows that hydrogenation of benzyl alcohol is significantly suppressed, which can be attributed to weakened adsorption of benzyl alcohol. This is most likely related to the modified electronic structure of Pd species via interaction with functionalized CNTs, as shown by XPS characterization. 展开更多
关键词 BENZALDEHYDE benzyl alcohol HYDROGENATION consecutive reaction N-doped carbon nanotube PALLADIUM
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Strategy for Synthesizing Novel Acetamidines as CO_2-Triggered Switchable Surfactants via Acetimidates 被引量:1
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作者 Yan Xu Fan Wang +3 位作者 Qingfeng Hou Yujun Zhao Guosheng Ding Xingguang Xu 《Transactions of Tianjin University》 EI CAS 2019年第3期237-244,共8页
In this study, we developed a strategy for using the Scoggins procedure in the synthesis of acetamidines as novel C02-triggered switchable surfactants via acetimidates by effectively tuning the chemical equilibrium. T... In this study, we developed a strategy for using the Scoggins procedure in the synthesis of acetamidines as novel C02-triggered switchable surfactants via acetimidates by effectively tuning the chemical equilibrium. The as-synthesized N'-alkyl-N,Ndiethylacetamidines exhibit excellent CO_2/N_2 switchability and their bicarbonate salts have the ability to emulsify oil-water mixtures. 展开更多
关键词 CO2 SWITCHABLE SURFACTANTS Acetimidate Acetamidine Consecutive REACTION
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APOPTOSIS AND PROLIFERATION OF TUMOR CELLS IN LOCALLY ADVANCED CERVICAL CANCER AFTER NEOADJUVANT INTRAARTERIAL CHEMOTHERAPY 被引量:1
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作者 朱雪琼 岳天孚 +2 位作者 惠京 张颖 王德华 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2003年第3期227-231,共5页
Objective: Through observing the clinical response toneoadjuvant intraarterial chemotherapy in locally advanced cervical cancer and investigating the changes of p53 proteinexpression, proliferation and apoptosis of tu... Objective: Through observing the clinical response toneoadjuvant intraarterial chemotherapy in locally advanced cervical cancer and investigating the changes of p53 proteinexpression, proliferation and apoptosis of tumor cells afterchemotherapy, to study the relationship between biological markers and chemotherapeutic response. Methods: 20women with locally advanced squamous cervical cancerreceived consecutive infusion chemotherapy of five days ofcisplatin and adriamycin via the superselective uterineartery. The response to chemotherapy was evaluated bygynecologic examination and ultrasonography 3 weeks after chemotherapy. The changes of apoptotic index (AI), proliferation index (PI) and p53 expression of tumor cellswere detected by immunohistochemical technique.Results: The clinical response rate of locally advancedsquamous cervical cancer to uterine artery infusionchemotherapy was 70%. No change of PI was found 3 weeks after treatment, but AI significantly increased from2.79?.76 to 4.29?.13 (P<0.01), and AI/PI from 5.68?.21 to 9.00?.95 (P<0.05). On the contrary, the expression of p53was significantly decreased (P<0.05). Patients whoresponded to chemotherapy showed higher PI before chemotherapy and significantly increased AI and AI/PIafter chemotherapy than non-responders (P<0.05).Conclusion: Higher PI was an indication for neoadjuvantintraarterial chemotherapy. One more cycle ofchemotherapy should be given to those who have significantly increased AI or AI/PI after chemotherapy, while definite treatment such as surgery or/and radiotherapy should be immediately given to those patients without increased AI or AI/PI. 展开更多
关键词 Neoadjuvant chemotherapy Consecutive artery infusion Cervical cancer APOPTOSIS PROLIFERATION p53
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A simulation study comparing the Texas two-step and the multistage consecutive fracturing method 被引量:1
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作者 Wan Cheng Guo-Sheng Jiang +3 位作者 Jing-Yu Xie Zi-Jun Wei Zhi-Dong Zhou Xiao-Dong Li 《Petroleum Science》 SCIE CAS CSCD 2019年第5期1121-1133,共13页
Multistage hydraulic fracturing in horizontal wells is a critical technique for developing unconventional oil and gas resources.Stress interactions among neighboring fractures cause immature fracture development.The T... Multistage hydraulic fracturing in horizontal wells is a critical technique for developing unconventional oil and gas resources.Stress interactions among neighboring fractures cause immature fracture development.The Texas two-step fracturing(TTSF)method is a new technique that aims to enhance fracture complexity and conductivity.This paper compares the fracture development of consecutive fracturing and the TTSF.The fracturing sequence in the multistage fracturing method has a significant effect on the fracture length,fracture width and injection pres sure.The consecutive fracturing results in relatively uneven fracture length and width.Certain fractures in consecutive fracturing are restrained to be closed due to the strong stress shadowing effect.In contrast,TTSF has considerable potential for alleviating the negative effects of stress interactions and producing a larger stimulated reservoir volume. 展开更多
关键词 Horizontal well Consecutive fracturing Texas two-step fracturing Hydraulic fracturing
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Extended consecutive modal pushover procedure for estimating seismic responses of one-way asymmetric plan tall buildings considering soil-structure interaction 被引量:1
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作者 Mohammad Hadikhan Tehrani Faramarz Khoshnoudian 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2014年第3期487-507,共21页
Performance based design becomes an effective method for estimating seismic demands of buildings. In asymmetric plan tall building the effects of higher modes and torsion are crucial. The consecutive modal pushover (... Performance based design becomes an effective method for estimating seismic demands of buildings. In asymmetric plan tall building the effects of higher modes and torsion are crucial. The consecutive modal pushover (CMP) procedure is one of the procedures that consider these effects. Also in previous studies the influence of soil-structure interaction (SSI) in pushover analysis is ignored. In this paper the CMP procedure is modified for one-way asymmetric plan mid and high-rise buildings considering $SI. The extended CMP (ECMP) procedure is proposed in order to overcome some limitations of the CMP procedure. In this regard, 10, 15 and 20 story buildings with asymmetric plan are studied considering SSI assuming three different soil conditions. Using nonlinear response history analysis under a set of bidirectional ground motion; the exact responses of these buildings are calculated. Then the ECMP procedure is evaluated by comparing the results of this procedure with nonlinear time history results as an exact solution as well as the modal pushover analysis procedure and FEMA 356 load patterns. The results demonstrate the accuracy of the ECMP procedure. 展开更多
关键词 consecutive modal pushover procedure soil-structure interaction bidirectional ground motion tall buildings seismic demands engineering demand parameters
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Advances of Allelopathic Autotoxicity in Rehmannia glutinosa L. 被引量:1
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作者 Xiaoran WANG Weixi LI +3 位作者 Zhen LI Yuhong WANG Zhongyi ZHANG Xinjian CHEN 《Agricultural Biotechnology》 CAS 2019年第3期46-50,53,共6页
Allelopathic autotoxicity occurs when a plant releases toxic chemical substances into the environment which inhibits development and growth of the same plant species.Rehmannia glutinosa L.( R.glutinosa ) is one of the... Allelopathic autotoxicity occurs when a plant releases toxic chemical substances into the environment which inhibits development and growth of the same plant species.Rehmannia glutinosa L.( R.glutinosa ) is one of the most common traditional Chinese medicines,whose productivity and quality,however,are seriously impacted by consecutive monoculture obstacle.Allelopathic autotoxicity is one reason for consecutive monoculture obstacle.In this paper,we reviewed the categories of allelochemicals,the methods of allelochemicals identification,and the mechanisms of allelopathic autotoxicity,which provides clues for further study of the molecular mechanisms of allelopathic autotoxicity and consecutive monoculture obstacle. 展开更多
关键词 REHMANNIA glutinosa Allelopathic AUTOTOXICITY Consecutive MONOCULTURE OBSTACLE AUTOTOXINS Self-DNA
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