[Objectives]Through data mining and analysis,the medication characters and ideas of ye Tianshi,a famous physician in Qing Dynasty,in the treatment of tinnitus were explored,so as to provide reference for clinical tinn...[Objectives]Through data mining and analysis,the medication characters and ideas of ye Tianshi,a famous physician in Qing Dynasty,in the treatment of tinnitus were explored,so as to provide reference for clinical tinnitus treatment.[Methods]The medical records of Ye Tianshi's treatment of tinnitus in the Ancient and Modern Consilia Cloud Platform were retrieved and sorted,and the use frequency,properties,metabolic organ and compatibility of related Chinese herbs in the cases were analyzed through system-integrated statistical analysis,cluster analysis,association rules analysis and complex network analysis.[Results]A total of 46 medical cases were finally included,with 15 frequently used Chinese herbs,including poria with hostwood,Radix Rehmanniae Preparata,magnetitum,etc.Most of the drugs are cold and neutral in nature,sweet and bitter in taste,and metabolized in liver and heart.The results of cluster analysis show that the therapeutic drugs for tinnitus are mainly divided into four categories:strengthening spleen,nourishing yin,suppressing symptoms,and clearing heat.The results of association rules analysis show that the commonly used traditional Chinese medicine combination is composed of three herbs,poria with hostwood,Radix Ophiopogonis,and Radix et Rhizoma Glycyrrhizae,which have spleen-strengthening and stomach-tonifying effects.The results of complex network analysis show that the core prescription is based on Siwu Decoction.[Conclusions]In the treatment of tinnitus,Ye Tianshi paid attention to the three internal organs of heart,kidney and gallbladder,and made good use of lung qi-dispersing drugs to clear heat,sweet and cold drugs to tonify stomach and nourish yin,and tonic drugs to suppress symptoms.The core prescription is mainly composed of Radix Rehmanniae,Radix Rehmanniae Preparata,oyster,poria with hostwood,Fructus Forsythiae,Radix Paeoniae Alba,antelope horn,magnetitum and Radix Asparagi.The commonly used single herbs are poria with hostwood,Radix Rehmanniae Preparata and magnetitum.The combination of poria with hostwood,Radix Ophiopogonis and Radix et Rhizoma Glycyrrhizae is more common.展开更多
基金Supported by The Second Batch of Training Projects for Excellent Clinical Talents of Traditional Chinese Medicine in Guangdong Province(Yue Zhong Yi Ban Han[2017]No.267).
文摘[Objectives]Through data mining and analysis,the medication characters and ideas of ye Tianshi,a famous physician in Qing Dynasty,in the treatment of tinnitus were explored,so as to provide reference for clinical tinnitus treatment.[Methods]The medical records of Ye Tianshi's treatment of tinnitus in the Ancient and Modern Consilia Cloud Platform were retrieved and sorted,and the use frequency,properties,metabolic organ and compatibility of related Chinese herbs in the cases were analyzed through system-integrated statistical analysis,cluster analysis,association rules analysis and complex network analysis.[Results]A total of 46 medical cases were finally included,with 15 frequently used Chinese herbs,including poria with hostwood,Radix Rehmanniae Preparata,magnetitum,etc.Most of the drugs are cold and neutral in nature,sweet and bitter in taste,and metabolized in liver and heart.The results of cluster analysis show that the therapeutic drugs for tinnitus are mainly divided into four categories:strengthening spleen,nourishing yin,suppressing symptoms,and clearing heat.The results of association rules analysis show that the commonly used traditional Chinese medicine combination is composed of three herbs,poria with hostwood,Radix Ophiopogonis,and Radix et Rhizoma Glycyrrhizae,which have spleen-strengthening and stomach-tonifying effects.The results of complex network analysis show that the core prescription is based on Siwu Decoction.[Conclusions]In the treatment of tinnitus,Ye Tianshi paid attention to the three internal organs of heart,kidney and gallbladder,and made good use of lung qi-dispersing drugs to clear heat,sweet and cold drugs to tonify stomach and nourish yin,and tonic drugs to suppress symptoms.The core prescription is mainly composed of Radix Rehmanniae,Radix Rehmanniae Preparata,oyster,poria with hostwood,Fructus Forsythiae,Radix Paeoniae Alba,antelope horn,magnetitum and Radix Asparagi.The commonly used single herbs are poria with hostwood,Radix Rehmanniae Preparata and magnetitum.The combination of poria with hostwood,Radix Ophiopogonis and Radix et Rhizoma Glycyrrhizae is more common.
