AIMTo determine the impact of rigid gas permeable (RGP) and silicone-hydrogel keratoconus lenses on the quality of life (QoL) in keratoconus (KCN) patients using the self-reported results from the Contact Lens Impact ...AIMTo determine the impact of rigid gas permeable (RGP) and silicone-hydrogel keratoconus lenses on the quality of life (QoL) in keratoconus (KCN) patients using the self-reported results from the Contact Lens Impact on Quality of Life (CLIQ) Questionnaire.METHODSFrom January 2013 to April 2013, 27 consecutive KCN patients who wore RGP contact lenses (conflexair100 UV KE Zeiss-Wöhlk) or soft silicone-hydrogel contact lenses (SHCLs) for KCN (KeraSoft IC- Bausch&Lomb or Hydrocone Toris K-Swiss lens) completed the CLIQ questionnaire.RESULTSThe mean age of 27 patients was 29.6±8.0y. Fifteen patients were RGP user. The groups were comparable with respect to the mean patient age, sex, and mean K values (P=0.1, P=0.8 and P=0.1, respectively). The mean CLIQperson measure was 42.8±5.5 in RGP group and 39.6±5.5 in SHCLs for KCN group (P=0.06). CLIQperson measure was positively correlated with steep K value (r=0.301, P=0.04). When eyes were stratified by visual acuity with contact lenses, the mean CLIQperson measure was 42.01±5.6 in eyes with a visual acuity of 20/20-20/25 (n=44) and 38.4±5.26 in eyes with a visual acuity of 20/32 or less (n=10; P=0.097).CONCLUSIONRGP lenses and SHCLs for KCN have similar impact on QoL.展开更多
AIM: To record aberrations with a corneal topographic device on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable (RGP) contact lenses. ...AIM: To record aberrations with a corneal topographic device on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable (RGP) contact lenses. The effect of wearing RGP on the anterior surface of the cornea was discussed to provide guidance for clinical refractive error correction.METHODS: The study objects were 24 eyes from 24 patients. All patients underwent identical examination procedures prior to lens use, as well as afterwards, including slit-lamp examination, non-contact tonometer measurement, computer optometry and corneal curvature measurement, subjective refraction test, and corneal topography analysis. The patients wore contact lenses everyday for 1 month and then discontinued. Corneal topographies were recorded at certain time points of 30 minutes, 1 day, 3, 7 and 14 days following use.RESULTS: Total corneal aberration at each time point following discontinued use of RGP contact lenses was less than the time point prior to use. Detailed results were as follows: root mean square (RMS) (pre)=(1.438± 0.328)μm, RMS (30 minutes) =(1.076 ±0.355)μm, RMS (1 day) =(1.362 ±0.402)μm, RMS (3 days) =(1.373 ±0.398)μm, RMS (7 days) =(1.387 ±0.415)μm, and RMS (14 days) = (1.430±0.423)μm. Results showed that at 30 minutes after discontinued use of RGP contact lenses, almost all 2 ndand 3 rd-order aberrations change. Quadrafoil Z10 and spherical Z12 of the 4 th-order were also changed. Alterations to Z5, Z6, and Z12 at 1 day after discontinued use were significant differences compared with the time period prior to RGP use: Z5 and Z6 decreased, and Z12 increased slightly. Z5 and Z6 remained decreased at 3 days after discontinued use, but Z9 and Z10 continued to increase and Z12 returned to levels prior to RGP use. At 14 days after discontinued use, all aberrations were notsignificantly different from the values prior to use.CONCLUSION: The use RGP contact lenses greatly reduced total aberration of the anterior surface of the cornea. Changes to 2 ndand 3 rd-order aberrations (including Z3, Z4, Z5, Z6, Z7, and Z8) were more significant. Following discontinued use of RGP contact lenses, the majority of lower order aberrations returned to original levels in a short period of time. During this process, a transient higher order aberration appeared, but all changes disappeared within 14 days after discontinued use of RGP contact lenses.展开更多
The prevalence of keratoconus is 1/2000 in the general population and is high in adolescents.Keratoconus is a progressive disease,which has a great impact on patients’quality of life and mental health.It can be manag...The prevalence of keratoconus is 1/2000 in the general population and is high in adolescents.Keratoconus is a progressive disease,which has a great impact on patients’quality of life and mental health.It can be managed by surgical and non-surgical means,rigid gas permeable(RGP)contact lens as its main non-surgical method is widely used in clinic.The efficacy of wearing RGP contact lens has been confirmed to some extent,but some studies have found that wearing RGP contact lens has adverse effects,which may promote disease progression.In this paper,the advantages and disadvantages of RGP contact lens in controlling keratoconus were reviewed to provide more suggestions and references for the clinical application of RGP contact lens.展开更多
AIM: To evaluate the effect of rigid gas permeable contact lens(RGP-CL) on corneal morphological parameters and vision-related quality of life in keratoconus(KC) patients.METHODS: Totally 57 eyes of 30 KC patients who...AIM: To evaluate the effect of rigid gas permeable contact lens(RGP-CL) on corneal morphological parameters and vision-related quality of life in keratoconus(KC) patients.METHODS: Totally 57 eyes of 30 KC patients who were followed-up for more than two years, including 17 RGP wearers(32 eyes) and 13 non-wearers(25 eyes) were retrospectively analyzed. Initial medical history and corneal topography were collected at baseline. Corneal topography, corneal aberration, optical coherence tomography, and vision-related quality of life questionnaires were performed at the last follow-up.RESULTS: According to corneal topography, increase of the flattest keratometric values was higher in RGP wearers than in non-wearers(P=0.038). The morphological parameters, including symmetry index of front corneal curvature(P=0.004) and Baiocchi-Calossi-Versaci index front(P=0.047), were lower in RGP wearers than in nonwearers. Vertical coma was smaller in RGP wearers than non-wearers in 3.0, 5.0, 6.0, and 7.0 mm pupil diameters, respectively(P<0.05). The environmental triggering domain of ocular surface disease index was worse in RGP wearers as compared to non-wearers(P=0.003). At the last followup, there were no significant differences in constituent ratios of KC progression, corneal thickness topography, epithelial thickness topography, morphological parameters of corneal topography, and other questionnaire scores between the two groups(all P>0.05).CONCLUSION: Long-term use of RGP does not worsen KC but may cause corneal epithelial remodeling to increase symmetry of corneal anterior surface, reduce corneal vertical coma and improve visual quality. However, RGP wearing causes a slight decrease in vision-related quality of life. The occurrence of ocular surface symptoms is mainly associated with environmental triggering factors.展开更多
Background:Evaluation of corneal biomechanical properties 3 months after using rigid gas permeable(RGP)contact lenses in keratoconus.Methods:In this prospective trial study,cases were 32 keratoconic eyes with no histo...Background:Evaluation of corneal biomechanical properties 3 months after using rigid gas permeable(RGP)contact lenses in keratoconus.Methods:In this prospective trial study,cases were 32 keratoconic eyes with no history of RGP lens wear.All eyes were examined with the Ocular Response Analyzer(ORA)and the Corneal Visualization Scheimpflug Technology(CORVIS-ST)to measure corneal hysteresis(CH),corneal resistance factor(CRF),deformation amplitude(DA),applanation velocity(AV)1 and 2,applanation length(AL)1 and 2,and peak distance before and 3 months after fitting aspheric RGP lenses.The effect of the correlation between contralateral eyes and maximum keratometry were controlled for in the analysis.Results were compared using repeated measures analysis of covariance.Results:At 3 months,neither the increases in mean CH(0.14±2.77 mm Hg,P=0.789),CRF(0.41±4.35 mm Hg,P=0.612),AV1(0.03±0.17 m/s,P=0.301),AV2(0.11±0.59 m/s,P=0.299),AL1(0.44±1.56 m/s,P=0.118),AL2(1.16±5.06 m/s,P=0.211),and peak distance(0.19±1.29 m/s,P=0.409),nor the decrease in mean DA(0.03±0.17 mm,P=0.402)was statistically significant.Conclusions:Results in our series of patients indicated that 3 months of RGP lens wear had no significant impact on corneal biomechanics,and perhaps non progression of keratoconus.Therefore,RGP lenses can be regarded safe and appropriate in keratoconic patients.展开更多
目的:研究硬性透氧性角膜接触镜(rigid gas permeable contact lens,RGP)对青少年复杂性屈光不正的矫正效果。方法:对51例90眼复杂屈光不正10～20岁的青少年患者给予验配RGP镜片,观察其矫正视力以及随访其并发症。结果:RGP镜片平均矫正...目的:研究硬性透氧性角膜接触镜(rigid gas permeable contact lens,RGP)对青少年复杂性屈光不正的矫正效果。方法:对51例90眼复杂屈光不正10～20岁的青少年患者给予验配RGP镜片,观察其矫正视力以及随访其并发症。结果:RGP镜片平均矫正视力为0.95±0.17,与框架眼镜平均矫正视力(0.39±0.11)相比,矫正视力有明显提高,差异有统计学意义(P<0.05)。所有病例均无严重并发症出现。结论:RGP镜片能有效提高复杂屈光不正患者的矫正视力,促进青少年视觉功能发育。展开更多
目的:初步观察Rose K硬性透氧性角膜接触镜(Rose K RGP)对圆锥角膜矫正视力的影响。方法:为经角膜地形图确诊为圆锥角膜的12例20眼验配Rose K RGP。该组病例球镜屈光度范围-1.00～-21.50DS;柱镜屈光度范围-1.25～-8.75DC。排除配戴禁忌...目的:初步观察Rose K硬性透氧性角膜接触镜(Rose K RGP)对圆锥角膜矫正视力的影响。方法:为经角膜地形图确诊为圆锥角膜的12例20眼验配Rose K RGP。该组病例球镜屈光度范围-1.00～-21.50DS;柱镜屈光度范围-1.25～-8.75DC。排除配戴禁忌证,经RGP规范验配程序(高度数球镜患者采用快速睫状肌麻痹检影,次日复查屈光度)和Rose K RGP试戴片戴镜验光,确定RGP镜片参数。配发镜片后,教育戴镜者依照规范操作方法及程序配戴和护理镜片。随访时间5～14mo。我们采用自身前后对照方法进行最佳矫正视力的对比研究。结果:该组病例中14眼(70%)为三点接触配适形态,5眼(25%)为顶点离开的配适形态,1眼(5%)为可接受的顶点接触配适形态。全部病例均能通过配戴Rose K RGP获得较框架眼镜更好的矫正视力(平均框架视力0.6±0.03,平均RGP视力0.9±0.05)。随访期内无严重并发症发生。结论:在角膜地形图指导下,圆锥角膜患者验配Rose K RGP容易达到比较理想的配适形态,获得较满意的矫正视力,矫正效果理想。展开更多
目的观察硬性透气性角膜接触镜(rigid gas permeable contact lens,RGPCL)与人工晶体睫状沟固定治疗无晶体眼的效果,比较两种方法治疗后的视力及散光情况。方法38例(39眼)无晶状体眼患者分为人工晶体睫状沟固定组(A组)和RGPCL组(B组),A...目的观察硬性透气性角膜接触镜(rigid gas permeable contact lens,RGPCL)与人工晶体睫状沟固定治疗无晶体眼的效果,比较两种方法治疗后的视力及散光情况。方法38例(39眼)无晶状体眼患者分为人工晶体睫状沟固定组(A组)和RGPCL组(B组),A组20例(21眼)行人工晶体睫状沟固定术,B组18例(18眼)行RGPCL矫正,分别记录治疗前裸眼视力及最佳矫正视力,以及治疗后7d、30d、90d视力和散光情况。结果两组治疗后视力和散光两者差别都有明显统计学意义(P<0.05),B组视力提高明显比A组视力提高较多,且B组残余散光明显小于A组。结论RGPCL在矫正无晶状体眼时较人工晶体睫状沟固定术视力提高更多,还能矫正患者部分不规则散光,同时并发症也少。展开更多
文摘AIMTo determine the impact of rigid gas permeable (RGP) and silicone-hydrogel keratoconus lenses on the quality of life (QoL) in keratoconus (KCN) patients using the self-reported results from the Contact Lens Impact on Quality of Life (CLIQ) Questionnaire.METHODSFrom January 2013 to April 2013, 27 consecutive KCN patients who wore RGP contact lenses (conflexair100 UV KE Zeiss-Wöhlk) or soft silicone-hydrogel contact lenses (SHCLs) for KCN (KeraSoft IC- Bausch&Lomb or Hydrocone Toris K-Swiss lens) completed the CLIQ questionnaire.RESULTSThe mean age of 27 patients was 29.6±8.0y. Fifteen patients were RGP user. The groups were comparable with respect to the mean patient age, sex, and mean K values (P=0.1, P=0.8 and P=0.1, respectively). The mean CLIQperson measure was 42.8±5.5 in RGP group and 39.6±5.5 in SHCLs for KCN group (P=0.06). CLIQperson measure was positively correlated with steep K value (r=0.301, P=0.04). When eyes were stratified by visual acuity with contact lenses, the mean CLIQperson measure was 42.01±5.6 in eyes with a visual acuity of 20/20-20/25 (n=44) and 38.4±5.26 in eyes with a visual acuity of 20/32 or less (n=10; P=0.097).CONCLUSIONRGP lenses and SHCLs for KCN have similar impact on QoL.
文摘AIM: To record aberrations with a corneal topographic device on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable (RGP) contact lenses. The effect of wearing RGP on the anterior surface of the cornea was discussed to provide guidance for clinical refractive error correction.METHODS: The study objects were 24 eyes from 24 patients. All patients underwent identical examination procedures prior to lens use, as well as afterwards, including slit-lamp examination, non-contact tonometer measurement, computer optometry and corneal curvature measurement, subjective refraction test, and corneal topography analysis. The patients wore contact lenses everyday for 1 month and then discontinued. Corneal topographies were recorded at certain time points of 30 minutes, 1 day, 3, 7 and 14 days following use.RESULTS: Total corneal aberration at each time point following discontinued use of RGP contact lenses was less than the time point prior to use. Detailed results were as follows: root mean square (RMS) (pre)=(1.438± 0.328)μm, RMS (30 minutes) =(1.076 ±0.355)μm, RMS (1 day) =(1.362 ±0.402)μm, RMS (3 days) =(1.373 ±0.398)μm, RMS (7 days) =(1.387 ±0.415)μm, and RMS (14 days) = (1.430±0.423)μm. Results showed that at 30 minutes after discontinued use of RGP contact lenses, almost all 2 ndand 3 rd-order aberrations change. Quadrafoil Z10 and spherical Z12 of the 4 th-order were also changed. Alterations to Z5, Z6, and Z12 at 1 day after discontinued use were significant differences compared with the time period prior to RGP use: Z5 and Z6 decreased, and Z12 increased slightly. Z5 and Z6 remained decreased at 3 days after discontinued use, but Z9 and Z10 continued to increase and Z12 returned to levels prior to RGP use. At 14 days after discontinued use, all aberrations were notsignificantly different from the values prior to use.CONCLUSION: The use RGP contact lenses greatly reduced total aberration of the anterior surface of the cornea. Changes to 2 ndand 3 rd-order aberrations (including Z3, Z4, Z5, Z6, Z7, and Z8) were more significant. Following discontinued use of RGP contact lenses, the majority of lower order aberrations returned to original levels in a short period of time. During this process, a transient higher order aberration appeared, but all changes disappeared within 14 days after discontinued use of RGP contact lenses.
基金Supported by the National Natural Science Foundation of China(No.81670837,No.81170828)the Tianjin Science&Technology Foundation(No.15JCZDJC35300)the Tianjin Health and Family Planning Communication Foundation(No.14KG133)。
文摘The prevalence of keratoconus is 1/2000 in the general population and is high in adolescents.Keratoconus is a progressive disease,which has a great impact on patients’quality of life and mental health.It can be managed by surgical and non-surgical means,rigid gas permeable(RGP)contact lens as its main non-surgical method is widely used in clinic.The efficacy of wearing RGP contact lens has been confirmed to some extent,but some studies have found that wearing RGP contact lens has adverse effects,which may promote disease progression.In this paper,the advantages and disadvantages of RGP contact lens in controlling keratoconus were reviewed to provide more suggestions and references for the clinical application of RGP contact lens.
文摘AIM: To evaluate the effect of rigid gas permeable contact lens(RGP-CL) on corneal morphological parameters and vision-related quality of life in keratoconus(KC) patients.METHODS: Totally 57 eyes of 30 KC patients who were followed-up for more than two years, including 17 RGP wearers(32 eyes) and 13 non-wearers(25 eyes) were retrospectively analyzed. Initial medical history and corneal topography were collected at baseline. Corneal topography, corneal aberration, optical coherence tomography, and vision-related quality of life questionnaires were performed at the last follow-up.RESULTS: According to corneal topography, increase of the flattest keratometric values was higher in RGP wearers than in non-wearers(P=0.038). The morphological parameters, including symmetry index of front corneal curvature(P=0.004) and Baiocchi-Calossi-Versaci index front(P=0.047), were lower in RGP wearers than in nonwearers. Vertical coma was smaller in RGP wearers than non-wearers in 3.0, 5.0, 6.0, and 7.0 mm pupil diameters, respectively(P<0.05). The environmental triggering domain of ocular surface disease index was worse in RGP wearers as compared to non-wearers(P=0.003). At the last followup, there were no significant differences in constituent ratios of KC progression, corneal thickness topography, epithelial thickness topography, morphological parameters of corneal topography, and other questionnaire scores between the two groups(all P>0.05).CONCLUSION: Long-term use of RGP does not worsen KC but may cause corneal epithelial remodeling to increase symmetry of corneal anterior surface, reduce corneal vertical coma and improve visual quality. However, RGP wearing causes a slight decrease in vision-related quality of life. The occurrence of ocular surface symptoms is mainly associated with environmental triggering factors.
文摘Background:Evaluation of corneal biomechanical properties 3 months after using rigid gas permeable(RGP)contact lenses in keratoconus.Methods:In this prospective trial study,cases were 32 keratoconic eyes with no history of RGP lens wear.All eyes were examined with the Ocular Response Analyzer(ORA)and the Corneal Visualization Scheimpflug Technology(CORVIS-ST)to measure corneal hysteresis(CH),corneal resistance factor(CRF),deformation amplitude(DA),applanation velocity(AV)1 and 2,applanation length(AL)1 and 2,and peak distance before and 3 months after fitting aspheric RGP lenses.The effect of the correlation between contralateral eyes and maximum keratometry were controlled for in the analysis.Results were compared using repeated measures analysis of covariance.Results:At 3 months,neither the increases in mean CH(0.14±2.77 mm Hg,P=0.789),CRF(0.41±4.35 mm Hg,P=0.612),AV1(0.03±0.17 m/s,P=0.301),AV2(0.11±0.59 m/s,P=0.299),AL1(0.44±1.56 m/s,P=0.118),AL2(1.16±5.06 m/s,P=0.211),and peak distance(0.19±1.29 m/s,P=0.409),nor the decrease in mean DA(0.03±0.17 mm,P=0.402)was statistically significant.Conclusions:Results in our series of patients indicated that 3 months of RGP lens wear had no significant impact on corneal biomechanics,and perhaps non progression of keratoconus.Therefore,RGP lenses can be regarded safe and appropriate in keratoconic patients.
文摘目的:研究硬性透氧性角膜接触镜(rigid gas permeable contact lens,RGP)对青少年复杂性屈光不正的矫正效果。方法:对51例90眼复杂屈光不正10～20岁的青少年患者给予验配RGP镜片,观察其矫正视力以及随访其并发症。结果:RGP镜片平均矫正视力为0.95±0.17,与框架眼镜平均矫正视力(0.39±0.11)相比,矫正视力有明显提高,差异有统计学意义(P<0.05)。所有病例均无严重并发症出现。结论:RGP镜片能有效提高复杂屈光不正患者的矫正视力,促进青少年视觉功能发育。
文摘目的:初步观察Rose K硬性透氧性角膜接触镜(Rose K RGP)对圆锥角膜矫正视力的影响。方法:为经角膜地形图确诊为圆锥角膜的12例20眼验配Rose K RGP。该组病例球镜屈光度范围-1.00～-21.50DS;柱镜屈光度范围-1.25～-8.75DC。排除配戴禁忌证,经RGP规范验配程序(高度数球镜患者采用快速睫状肌麻痹检影,次日复查屈光度)和Rose K RGP试戴片戴镜验光,确定RGP镜片参数。配发镜片后,教育戴镜者依照规范操作方法及程序配戴和护理镜片。随访时间5～14mo。我们采用自身前后对照方法进行最佳矫正视力的对比研究。结果:该组病例中14眼(70%)为三点接触配适形态,5眼(25%)为顶点离开的配适形态,1眼(5%)为可接受的顶点接触配适形态。全部病例均能通过配戴Rose K RGP获得较框架眼镜更好的矫正视力(平均框架视力0.6±0.03,平均RGP视力0.9±0.05)。随访期内无严重并发症发生。结论:在角膜地形图指导下,圆锥角膜患者验配Rose K RGP容易达到比较理想的配适形态,获得较满意的矫正视力,矫正效果理想。
文摘目的观察硬性透气性角膜接触镜(rigid gas permeable contact lens,RGPCL)与人工晶体睫状沟固定治疗无晶体眼的效果,比较两种方法治疗后的视力及散光情况。方法38例(39眼)无晶状体眼患者分为人工晶体睫状沟固定组(A组)和RGPCL组(B组),A组20例(21眼)行人工晶体睫状沟固定术,B组18例(18眼)行RGPCL矫正,分别记录治疗前裸眼视力及最佳矫正视力,以及治疗后7d、30d、90d视力和散光情况。结果两组治疗后视力和散光两者差别都有明显统计学意义(P<0.05),B组视力提高明显比A组视力提高较多,且B组残余散光明显小于A组。结论RGPCL在矫正无晶状体眼时较人工晶体睫状沟固定术视力提高更多,还能矫正患者部分不规则散光,同时并发症也少。
