Script-Based GPU-Ready ELM Development for Continuous Code Integration

Designing and optimizing complex scientific code for new computing architectures is a challenging task. To address this issue in the E3SM land model (ELM) development, we developed a software tool called SPEL, which facilitates code generation, verification, and performance tuning using compiler directives within a Function Unit Test framework. In this paper, we present a SPEL extension that leverages the version control system (e.g., Git) to autonomous code generation and demonstrate its application to continuous code integration and development of the ELM software system. The study can benefit the scientific software development community.

Microarrow sensor array with enhanced skin adhesion for transdermal continuous monitoring of glucose and reactive oxygen species

Conventional blood sampling for glucose detection is prone to cause pain and fails to continuously record glucose fluctuations in vivo.Continuous glucose monitoring based on implantable electrodes could induce pain and potential tissue inflammation,and the presence of reactive oxygen species(ROS)due to inflammationmay affect glucose detection.Microneedle technology is less invasive,yet microneedle adhesion with skin tissue is limited.In this work,we developed a microarrow sensor array(MASA),which provided enhanced skin surface adhesion and enabled simultaneous detection of glucose and H_(2)O_(2)(representative of ROS)in interstitial fluid in vivo.The microarrows fabricated via laser micromachining were modified with functional coating and integrated into a patch of a three-dimensional(3D)microneedle array.Due to the arrow tip mechanically interlocking with the tissue,the microarrow array could better adhere to the skin surface after penetration into skin.The MASA was demonstrated to provide continuous in vivo monitoring of glucose and H_(2)O_(2) concentrations,with the detection of H_(2)O_(2) providing a valuable reference for assessing the inflammation state.Finally,the MASA was integrated into a monitoring system using custom circuitry.This work provides a promising tool for the stable and reliable monitoring of blood glucose in diabetic patients.

Scalable and fast fabrication of graphene integrated micro-supercapacitors with remarkable volumetric capacitance and flexibility through continuous centrifugal coating

Microscale electrochemical energy storage devices,e.g., micro-supercapacitors(MSCs),possessing tailored performance and diversified form factors of lightweight,miniaturization,flexibility and exceptional integration are highly necessary for the smart power sources-unitized electronics.Despite the great progress,the fabrication of MSCs combining high integration with high volumetric performance remains largely unsolved.Herein,we develop a simple,fast and scalable strategy to fabricate graphene based highly integrated MSCs by a new effective continuous centrifugal coating technique.Notably,the resulting highly conductive graphene films can act as not only patterned microelectrodes but also metal-free current collectors and interconnects,endowing modular MSCs with high integrity,remarkable flexibility,tailored voltage and capacitance output,and outstanding performance uniformity.More importantly,the strong centrifugal force and shear force generated in continuous centrifugal coating process lead to graphene films with high alignment,compactness and packing density,contributing to excellent volumetric capacitance of ~31.8 F cm^(-3) and volumetric energy density of ~2.8 mWh cm^(-3),exceeding most reported integrated MSCs.Therefore,our work paves a novel way for simple and scalable fabrication of integrated MSCs and offers promising opportunities as standalone microscale power sources for new-generation electronics.

Evaluation of vertical impact factor coefficients for continuous and integral railway bridges under high-speed moving loads

In the railway bridge analysis and design method,dynamic train loads are regarded as static loads enhanced by an impact factor(IF).The IF coefficients for various railway bridges have been reported as a function of span length or frequency of the bridges in Eurocode(2003).However,these IF coefficient values neglect the effects of very high speeds(>200 km/h)and soil-structure interaction(SSI).In this work,a comprehensive study to assess the impact factor coefficients of mid-span vertical displacements for continuous and integral railway bridges subjected to high-speed moving loads is reported.Three different configurations,each for the three-dimensional(3D)continuous and integral bridge,are considered.Also,single-track(1-T)and two-track(2-T)“real train”loading cases for both these bridge types are considered.Subsequently,finite element analysis of the full-scale 3D bridge models,to identify their IF values,considering the effects of SSI for three different soil conditions,is conducted.The IF values obtained from the study for both bridge types are comparable and are greater than the values recommended by Eurocode(2003).The results reveal that with a loss of soil stiffness,the IF value reduces;thus,it confirms the importance of SSI analysis.

CONTINUOUS IMPROVEMENT THROUGH INTEGRATION OF QUALITY TOOLS

The relationship between major quality tools such as quality function development （QFD）, failure mode and effects analysis （FMEA）, design of experiments （DOE） and statistical process control （SPC） is analyzed through an extensive review of the literature and the concurrent quality engineering philosophy, and a basic structure for the integration of quality tools is presented. An integrated quality management system （IQMS） is developed using C＋＋ Builder, running in the Windows 2000 Server environment with the basic internet connections, and SQL Server 2000 as the platform for developing the database, An illustrative example applying IQMS to the continuous quality improvement for a crane equipment manufacturing is reported. The result shows that the application of IQMS can optimize the process of design and manufacturing, shorten the cycle time of product, reduce the cost, and realize quality improvement continuously, The proposed integrated framework with IOMS is believed to be applicable to continuous quality improvement in many manufacturing companies.

Integrated continuous replenishment planning in VMI system of retail industry

In order to let suppliers monitor customers＇ inventory levels and make supply decisions regarding order quantities and delivery time, an integrated continuous replenishment planning （CRP） strategy of fresh food oriented to retail industry is presented, which integrates the consolidation of shipment and inventory replenishment considering the deterioration of items to guarantee the quality safety of fresh food during the replenishment cycle. A vendor managed inventory （VMI） mathematical model to compute upper-level inventory and delivery cycle is built. Based on the real-time sales data exchange, it enables suppliers to make the decision of the optimal time and the quantities of replenishment for retailers during a delivery cycle, in order to replenish the consumers＇ stock initiatively and minimize the long-run average cost.

Role of hepatitis B virus DNA integration in human hepatocarcinogenesis

Liver cancer ranks sixth in cancer incidence, and is the third leading cause of cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, which arises from hepatocytes and accounts for approximately 70%-85% of cases. Hepatitis B virus (HBV) frequently causes liver inflammation, hepatic damage and subsequent cirrhosis. Integrated viral DNA is found in 85%-90% of HBV-related HCCs. Its presence in tumors from non-cirrhotic livers of children or young adults further supports the role of viral DNA integration in hepatocarcinogenesis. Integration of subgenomic HBV DNA fragments into different locations within the host DNA is a significant feature of chronic HBV infection. Integration has two potential consequences: (1) the host genome becomes altered (“cis” effect); and (2) the HBV genome becomes altered (“trans” effect). The cis effect includes insertional mutagenesis, which can potentially disrupt host gene function or alter host gene regulation. Tumor progression is frequently associated with rearrangement and partial gain or loss of both viral and host sequences. However, the role of integrated HBV DNA in hepatocarcinogenesis remains controversial. Modern technology has provided a new paradigm to further our understanding of disease mechanisms. This review summarizes the role of HBV DNA integration in human carcinogenesis.

Integrated design optimization of composite frames and materials for maximum fundamental frequency with continuous fiber winding angles

Fiber reinforced composite frame structure is an ideal lightweight and large-span structure in the fields of aerospace,satellite and wind turbine.Natural fundamental frequency is one of key indicators in the design requirement of the composite frame since structural resonance can be effectively avoided with the increase of the fundamental frequency.Inspired by the concept of integrated design optmization of composite frame structures and materials,the design optimization for the maximum structural fundamental frequency of fiber reinforced frame structures is proposed.An optimization model oriented at the maximum structural fundamental frequency under a composite material volume constraint is established.Two kinds of independent design variables are optimized,in which one is variables represented structural topology,the other is variables of continuous fiber winding angles.Sensitivity analysis of the frequency with respect to the two kinds of independent design variables is implemented with the semi-analytical sensitivity method.Some representative examples in the manuscript demonstrate that the integrated design optimization of composite structures can effectively explore coupled effects between structural configurations and material properties to increase the structural fundamental frequency.The proposed integrated optimization model has great potential to improve composite frames structural dynamic performance in aerospace industries.

The Static Stability Region of an Integrated Electricity-Gas System Considering Voltage and Gas Pressure

In an integrated electricity-gas system(IEGS),load fluctuations affect not only the voltage in the power system but also the gas pressure in the natural gas system.The static voltage stability region(SVSR)method is a tool for analyzing the overall static voltage stability in a power system.However,in an IEGS,the SVSR boundary may be overly optimistic because the gas pressure may collapse before the voltage collapses.Thus,the SVSR method cannot be directly applied to an IEGS.In this paper,the concept of the SVSR is extended to the IEGS-static stability region(SSR)while considering voltage and gas pressure.First,criteria for static gas pressure stability in a natural gas system are proposed,based on the static voltage stability criteria in a power system.Then,the IEGS-SSR is defined as a set of active power injections that satisfies multi-energy flow(MEF)equations and static voltage and gas pressure stability constraints in the active power injection space of natural gas-fired generator units(NGUs).To determine the IEGSSSR,a continuation MEF(CMEF)method is employed to trace the boundary point in one specific NGU scheduling direction.A multidimensional hyperplane sampling method is also proposed to sample the NGU scheduling directions evenly.The obtained boundary points are further used to form the IEGSSSR in three-dimensional(3D)space via a Delaunay triangulation hypersurface fitting method.Finally,the numerical results of typical case studies are presented to demonstrate that the proposed method can effectively form the IEGS-SSR,providing a tool for IEGS online monitoring and dispatching.

基于PPO算法的CIES低碳优化调度方法

阶梯式碳交易机制以及优化调度模型求解算法是进行园区综合能源系统(community integrated energy system,CIES)优化调度的重要因素,现有文献对这两个因素的考虑不够全面。为此,文中在考虑阶梯式碳交易机制的基础上,提出采用近端策略优化(proximal policy optimization,PPO)算法求解CIES低碳优化调度问题。该方法基于低碳优化调度模型搭建强化学习交互环境,利用设备状态参数及运行参数定义智能体的状态、动作空间及奖励函数,再通过离线训练获取可生成最优策略的智能体。算例分析结果表明,采用PPO算法得到的CIES低碳优化调度方法能够充分发挥阶梯式碳交易机制减少碳排放量和提高能源利用率方面的优势。

L2 Syntactic Alignment in the Reading-Writing Integrated Continuation Task: Evidence From Chinese EFL Learners’ Description of Motion Events

This study investigated how the mode in which the reading-writing integrated continuation task was conducted modulates the effects of second language(L2) syntactic alignment, through the English motion event construction with manner verbs. Ninety Chinese students were assigned to either of the two experimental groups or a control group, and they all experienced a pretest, an alignment phase and a posttest. In the alignment phase, the two experimental groups completed a reading-writing integrated continuation task but in different modes. For the multi-turn mode,participants reconstructed a picture story by continuing the episodes extracted from the story with one episode presented and continued at a time;for the single-turn mode, the first half of the same picture story was presented as a chunk, and then participants read and continued it. Results show that L2 learners aligned with the target structure in completing the story, and the alignment effect was retained in the posttest conducted after a delay of two weeks. Moreover, syntactic alignment was modulated by task mode with the multi-turn group exhibiting stronger immediate and longterm alignment effects. We conclude that the continuation task is a fruitful context for L2 structural alignment, and the magnitude of alignment effect hinges on interactive intensity.

Continuous Dependence of Bounded Φ-variation Solutions on Parameter for a Class of Discontinuous Systems

The functions of bounded φ-variation are development and generalization of bounded variation functions in the usual sense.Henstock-Kurzweil integral is a very useful tool for some discontinuous systems. In this paper, by using Henstock-Kurzweil integral, we establish theorems of continuous dependence of bounded D-variation solutions on parameter for a class of discontinuous systems on the base of D-function. These results are essential generalizations of continuous dependence of bounded variation solutions on parameter for the systems.

Downward continuation of airborne gravimetry data based on Poisson integral iteration method

The research and application of airborne gravimetry technology has become one of the hottest topics in gravity field in recent years. Downward continuation is one of the key steps in airborne gravimetry data processing, and the quality of continuation results directly influence the further application of surveying data. The Poisson integral iteration method is proposed in this paper, and the modified Poisson integral discretization formulae are also introduced in the downward continuation of airborne gravimerty data. For the test area in this paper, compared with traditional Poisson integral discretization formula, the continuation result of modified formulae is improved by 10.8 mGal, and the precision of Poisson integral iteration method is in the same amplitude as modified formulae. So the Poisson integral iteration method can reduce the discretization error of Poisson integral formula effectively. Therefore, the research achievements in this paper can be applied directly in the data processing of our country＇s airborne scalar and vector gravimetry.

Expert consensus on diagnosis and treatment of ulcerative colitis with integrated traditional Chinese and Western medicine:A nursing perspective

Ulcerative colitis(UC)is a chronic nonspecific intestinal inflammatory disease of unclear etiology,characterized by continuous and diffuse inflammatory changes of colorectal mucosa.In recent years,the incidence rate of UC in China has increased year by year,but there is no effective cure method in Western medicine.Traditional Chinese medicine treatment based on syndrome differentiation has the unique advantages of simplicity,convenience,effectiveness,and low cost.Therefore,integration of Chinese and Western medicine has become an important strategy for UC diagnosis and treatment,and has made significant progress in UC.On the basis of learning from a number of consensuses at home and abroad,combined with Chinese research results and the actual clinical situation of traditional Chinese and Western medicine,the UC group of the Chinese Association of Integrative Medicine has formulated the expert consensus on the diagnosis and treatment of UC with integrated traditional Chinese and Western medicine.In this consensus,the pathogenesis,etiology and pathogenesis,diagnosis,integrated traditional Chinese and Western medicine treatment,and chronic disease management with integrated traditional Chinese and Western medicine for UC were recommended by experts.This article interprets the consensus from the perspective of nursing in order to provide reference basis for clinical nursing workers.

THE INTEGRATION OF ALGEBROIDAL FUNCTIONS

In this paper, we introduce the integration of algebroidal functions on Riemann surfaces for the first time. Some properties of integration are obtained. By giving the defi- nition of residues and integral function element, we obtain the condition that the integral is independent of path. At last, we prove that the integral of an irreducible algebroidal function is also an irreducible algebroidal function if all the residues at critical points are zeros.

Recent Developments in the Continuous Processing of Steels

This paper reviews recent developments in the contin- uous processing of steels in Japan.The following items are discussed:continuous casting-direct rolling(CC-DR) process of hot-rolled strip:thermomechanical control process(TMCP)of heavy plates:in—line heat treating pro- cess of rails:direct lead patenting(DLP)process of wire rods;and fully integrated processing line(FIPL)of cold-rolled strip.

CONTINUOUS FRAME WAVELETS

Let π be a unitary representation of a locally compact topological group G on a separable Hilbert space H. A vector ψ∈ H is called a continuous frame wavelet if there exist A, B 〉 0 such that A｜｜Ф｜｜2≤fG｜〈π（G）ψ,Ф｜2dg≤B｜｜Ф｜｜2（Ф∈H）,in which dg is the left Haar measure of G. Similar to the study of wavelets, an essential problem in the study of continuous frame wavelets is how to characterize them under the given unitary representation. Moreover, we investigate a relation between admissible vectors of π and its components.

Continuous Quantum Nondemolition Measurements of a Particle in Electromagnetic and Gravitational Fields

The detection of a particle in electromagnetic plus gravitational fields is investigated. We obtain a set of quantum nondemolition variables. The continuous measurements of these nondemolition parameters are analyzed in the framework of restricted path integral formalism. We manipulate the corresponding propagators, and deduce the probabilities associated with the possible measurement outputs.

Applications of Analytic Continuation to Tables of Integral Transforms and Some Integral Equations with Hyper-Singular Kernels

Analytic continuation of some classical formulas with respect to a parameter is discussed. Examples are presented. The validity of these formulas is greatly expanded. Application of these results to solving some integral equations with hyper-singular kernels is given.