The emergence of coronavirus disease-2019 induced by a newly identified bcoronavirus, namely severe acute respiratory syndrome coronavirus 2(SARSCoV-2) has constituted a public health emergency. Even though it was con...The emergence of coronavirus disease-2019 induced by a newly identified bcoronavirus, namely severe acute respiratory syndrome coronavirus 2(SARSCoV-2) has constituted a public health emergency. Even though it was considered a zoonotic disease, the virus has also spread among humans via respiratory secretions. The expression and distribution of angiotensin converting enzyme type 2(ACE2) in various human organs might also show other possible infection routes. High ACE2 ribonucleic acid expression has been identified in the gastrointestinal tract(GI) indicating its importance as a possible infection pathway of SARS-CoV-2. ACE2 induces viral entry into the host and most importantly has been found to be associated with the function of the gut. Its deficiency has been implicated in several pathologies such as colorectal inflammation. The renin-angiotensin system(RAS) is an essential regulatory cascade operating both at a local tissue level and at the systemic or circulatory level. The RAS may be important in the pathogenesis of chronic liver disease and is associated with the up-regulation of ACE2. Thus, the aim of this review is firstly, the analysis of some important general and genome characteristics of SARS-CoV-2 and secondly, and most importantly, to focus on the utility of ACE2 receptors in both SARS-CoV-2 replication and pathogenesis, especially in the GI tract.展开更多
Through a third⁃order mathematical model of grid⁃oriented LCL⁃type converters,this paper analyzes the complicated dynamic characteristics and resonance problems which may influence the system stability.To realize acti...Through a third⁃order mathematical model of grid⁃oriented LCL⁃type converters,this paper analyzes the complicated dynamic characteristics and resonance problems which may influence the system stability.To realize active damping for LCL filters and improve dynamic performance of current regulators,a state space current PI controller is proposed whose parameters can be tuned based on the polynomial equations approach.An extended state observer is integrated with the regulation scheme,where additional sensors are not necessary in contrast with conventional active damping strategies.Synchronous reference frame PLL(SRF⁃PLL)equipped with filter technology is proposed for grid voltage disturbance suppression.This method is then applied to establish a double⁃closed⁃loop power regulator that demonstrates improved performance compared with other controllers.The simulation results are displayed to illustrate the efficiency of the regulation methods.展开更多
文摘The emergence of coronavirus disease-2019 induced by a newly identified bcoronavirus, namely severe acute respiratory syndrome coronavirus 2(SARSCoV-2) has constituted a public health emergency. Even though it was considered a zoonotic disease, the virus has also spread among humans via respiratory secretions. The expression and distribution of angiotensin converting enzyme type 2(ACE2) in various human organs might also show other possible infection routes. High ACE2 ribonucleic acid expression has been identified in the gastrointestinal tract(GI) indicating its importance as a possible infection pathway of SARS-CoV-2. ACE2 induces viral entry into the host and most importantly has been found to be associated with the function of the gut. Its deficiency has been implicated in several pathologies such as colorectal inflammation. The renin-angiotensin system(RAS) is an essential regulatory cascade operating both at a local tissue level and at the systemic or circulatory level. The RAS may be important in the pathogenesis of chronic liver disease and is associated with the up-regulation of ACE2. Thus, the aim of this review is firstly, the analysis of some important general and genome characteristics of SARS-CoV-2 and secondly, and most importantly, to focus on the utility of ACE2 receptors in both SARS-CoV-2 replication and pathogenesis, especially in the GI tract.
文摘Through a third⁃order mathematical model of grid⁃oriented LCL⁃type converters,this paper analyzes the complicated dynamic characteristics and resonance problems which may influence the system stability.To realize active damping for LCL filters and improve dynamic performance of current regulators,a state space current PI controller is proposed whose parameters can be tuned based on the polynomial equations approach.An extended state observer is integrated with the regulation scheme,where additional sensors are not necessary in contrast with conventional active damping strategies.Synchronous reference frame PLL(SRF⁃PLL)equipped with filter technology is proposed for grid voltage disturbance suppression.This method is then applied to establish a double⁃closed⁃loop power regulator that demonstrates improved performance compared with other controllers.The simulation results are displayed to illustrate the efficiency of the regulation methods.
