An efficient approach for the synthesis of N-arylated amides was developed via copper(Ⅱ) triflate-catalyzed direct oxidation of(aryl)methylamines to primary arylamides by air and subsequent N-arylation by diaryliodon...An efficient approach for the synthesis of N-arylated amides was developed via copper(Ⅱ) triflate-catalyzed direct oxidation of(aryl)methylamines to primary arylamides by air and subsequent N-arylation by diaryliodonium salts. Various substituted benzylamines could be applied in the reaction, providing a series of N-arylated amides in moderate to good yields. This method showed convenient, practical, and environment friendly advantages.展开更多
A facile and efficient one-pot three-component synthesis of bis（5-methyl-2-furyl）methanes has been achieved via the reaction of 2-methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones i...A facile and efficient one-pot three-component synthesis of bis（5-methyl-2-furyl）methanes has been achieved via the reaction of 2-methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones in presence of copper（II） triflate under solvent free conditions. The bis（5-methyl-2-furyl）methanes were obtained in 34%--72% yields and the catalyst was recycled up to four successive cycles without much loss in catalytic activity.展开更多
The regioselective ring-opening of epoxides with aniline and p-chlorop niline catalyzed by copper(Ⅱ) triflate provides the corresponding β-amino alcohols in excellent yields.
基金This work was financially supported by the National Nature Science Foundation of China(21272069,20672035)the Fundamental Reearch Funds for the Central Universities and Key Laboratory of Organofluorine Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences.
文摘An efficient approach for the synthesis of N-arylated amides was developed via copper(Ⅱ) triflate-catalyzed direct oxidation of(aryl)methylamines to primary arylamides by air and subsequent N-arylation by diaryliodonium salts. Various substituted benzylamines could be applied in the reaction, providing a series of N-arylated amides in moderate to good yields. This method showed convenient, practical, and environment friendly advantages.
文摘A facile and efficient one-pot three-component synthesis of bis（5-methyl-2-furyl）methanes has been achieved via the reaction of 2-methylfuran with a series of aliphatic and aromatic aldehydes and aliphatic ketones in presence of copper（II） triflate under solvent free conditions. The bis（5-methyl-2-furyl）methanes were obtained in 34%--72% yields and the catalyst was recycled up to four successive cycles without much loss in catalytic activity.
基金Project (No. 29790127) supported by the National Natural Science Foundation of China
文摘The regioselective ring-opening of epoxides with aniline and p-chlorop niline catalyzed by copper(Ⅱ) triflate provides the corresponding β-amino alcohols in excellent yields.
