期刊文献+
共找到1,354篇文章
< 1 2 68 >
每页显示 20 50 100
Drug-coated balloons for treating de novo lesions in large coronary vessels:A case report
1
作者 Zhi-Qiang Zhang Yi-Ran Qin +4 位作者 Man Yin Xue-Heng Chen Lei Chen Wen-Yan Liang Xi-Qing Wei 《World Journal of Clinical Cases》 SCIE 2023年第20期4920-4925,共6页
BACKGROUND Percutaneous transluminal coronary angioplasty,while an effective intervention,can frequently lead to acute occlusion with severe consequences.Although clinical trials have demonstrated the efficacy of drug... BACKGROUND Percutaneous transluminal coronary angioplasty,while an effective intervention,can frequently lead to acute occlusion with severe consequences.Although clinical trials have demonstrated the efficacy of drug-coated balloons(DCB)in treating acute coronary artery occlusion and in preventing restenosis,there has been limited exploration on the use of DCB in treating de novo lesions in large vessels.Currently,DCB are only recommended for patients with small vessel lesions and in-stent restenosis lesions,those at high risk of bleeding,and other special groups of patients.CASE SUMMARY This report presents a case of successful drug-coated balloon treatment of de novo lesions in large coronary vessels.Postoperatively,the patient demonstrated favorable recovery,with subsequent examination results revealing no significant differences from the previous examination.CONCLUSION The successful treatment of the patient in our case highlights the potential of DCB in the treatment of de novo lesions in large coronary vessels. 展开更多
关键词 Drug-coated balloons De novo lesions Large coronary vessels coronary artery disease Percutaneous coronary intervention Case report
下载PDF
Protocol to study the effects of AMPK-mTOR/PINK-Parkin dual signaling pathways on the formation of coronary heart disease showing blood stasis symptom pattern based on traditional Chinese medicine theory of“heart governing blood and vessels”
2
作者 An-Ni Chen Man-Li Zhou +4 位作者 Yun-Feng Yu Kang-Yan Tang Lin-Juan Yang Mo-Fei Shi Wei-Xiong Jian 《Aging Communications》 2023年第3期18-22,共5页
In this study,we aim to combine gene transfection techniques with the modeling methods previously employed by the research group to deeply investigate the corresponding theories of traditional Chinese medicine regard... In this study,we aim to combine gene transfection techniques with the modeling methods previously employed by the research group to deeply investigate the corresponding theories of traditional Chinese medicine regarding“myocardial energy metabolism”and“aortic thrombosis”.Our goal is to elucidate the biological mechanism underlying the occurrence and development of coronary heart disease with blood stasis syndrome from the perspectives of“heart and vessels”and“Qi(in traditional Chinese medicine,it refers to the most fundamental and subtle substances that constitute the human body and maintain life activities.At the same time,it also has the meaning of physiological function.In terms of traditional Chinese medicine,Qi and different words are used together to express different meanings)and blood”.The research content is divided into four modules as follows:1.establishment of an animal model of coronary heart disease with blood stasis syndrome through fibrinogen overexpression.2.Investigation of the mitochondrial quality control system in coronary heart disease with blood stasis syndrome under fibrinogen overexpression.3.Study of platelet autophagy in coronary heart disease with blood stasis syndrome under fibrinogen overexpression.4.Examination of the relationship between the AMPK-mTOR pathway and metabolism in platelet autophagy of coronary heart disease with blood stasis syndrome under fibrinogen overexpression.Ninety-six Sprague Dawley rats will be randomly assigned to the following groups:control group,model group,fibrinogen group and adeno-associated virus group.All rats will undergo a 14-week model construction process,and modern molecular biology methods will be employed to evaluate the model and examine relevant research indicators.The obtained data will be analyzed according to a predefined statistical analysis plan. 展开更多
关键词 coronary heart disease with blood stasis syndrome heart governing blood and vessels AMPK-mTOR/PINK-Parkin energy metabolism platelet autophagy study protocol
下载PDF
Evaluation of Clinical Outcomes of ses Stent in Patients with Coronary Artery Disease After Intracoronary Stenting in Small Vessels
3
作者 葛长江 吕树铮 柳弘 《心肺血管病杂志》 CAS 2010年第S1期67-67,共1页
Background:Limited data are available for sirolimus-eluting stent(SES,Cypher)implantation in patients with coronary artery disease in small vessels.The clinical longtermoutcomes of SES in patients with coronary artery... Background:Limited data are available for sirolimus-eluting stent(SES,Cypher)implantation in patients with coronary artery disease in small vessels.The clinical longtermoutcomes of SES in patients with coronary artery disease after intracoronary stenting in small vessels has not been yet evaluated. 展开更多
关键词 Evaluation of Clinical Outcomes of ses Stent in Patients with coronary Artery Disease After Intracoronary Stenting in Small vessels
下载PDF
Ultrasound-assessed non-culprit and culprit coronary vessels differ by age and gender 被引量:8
4
作者 Andreas W Schoenenberger Nadja Urbanek +3 位作者 Stefan Toggweiler Andreas E Stuck Thérèse J Resink Paul Erne 《World Journal of Cardiology》 CAS 2013年第3期42-48,共7页
AIM: To investigate age-and gender-related differences in non-culprit versus culprit coronary vessels assessed with virtual histology intravascular ultrasound (VH-IVUS). METHODS: In 390 patients referred for coronary ... AIM: To investigate age-and gender-related differences in non-culprit versus culprit coronary vessels assessed with virtual histology intravascular ultrasound (VH-IVUS). METHODS: In 390 patients referred for coronary angiography to a single center (Luzerner Kantonsspital, Switzerland) between May 2007 and January 2011, 691 proximal vessel segments in left anterior descending, circumflex and/or right coronary arteries were imaged by VH-IVUS. Plaque burden and plaque composition(fibrous, fibro-fatty, necrotic core and dense calcium volumes) were analyzed in 3 age tertiles, according to gender and separated for vessels containing non-culprit or culprit lesions. To classify as vessel containing a culprit lesion, the patient had to present with an acute coronary syndrome, and the VH-IVUS had to be performed in a vessel segment containing the culprit lesion according to conventional coronary angiography. RESULTS: In non-culprit vessels the plaque burden increased significantly with aging (in men from 37% ± 12% in the lowest to 46% ± 10% in the highest age tertile, P < 0.001; in women from 30% ± 9% to 40% ± 11%, P < 0.001); men had higher plaque burden than women at any age (P < 0.001 for each of the 3 age tertiles). In culprit vessels of the lowest age tertile, plaque burden was significantly higher than that in non- culprit vessels (in men 48% ± 6%, P < 0.001 as compared to non-culprit vessels; in women 44% ± 18%, P = 0.004 as compared to non-culprit vessels). Plaque burden of culprit vessels did not significantly change during aging (plaque burden in men of the highest age tertile 51% ± 9%, P = 0.523 as compared to lowest age tertile; in women of the highest age tertile 49% ± 8%, P = 0.449 as compared to lowest age tertile). In men, plaque morphology of culprit vessels became increasingly rupture-prone during aging (increasing percentages of necrotic core and dense calcium), whereas plaque morphology in non-culprit vessels was less rupture-prone and remained constant during aging. In women, necrotic core in non-culprit vessels was very low at young age, but increased during aging resulting in a plaque morphology that was very similar to men. Plaque morphology in culprit vessels of young women and men was similar. CONCLUSION: This study provides evidence that age-and gender-related differences in plaque burden and plaque composition significantly depend on whether the vessel contained a non-culprit or culprit lesion. 展开更多
关键词 coronary vessels ANATOMY and HISTOLOGY coronary ARTERY ULTRASONOGRAPHY coronary ARTERY disease Atherosclerosis ETIOLOGY Age factors
下载PDF
Challenging situation of coronary artery anomaly associated with ischemia and/or risk of sudden death
5
作者 Shigenori Ito 《World Journal of Cardiology》 2024年第4期173-176,共4页
Coronary artery anomaly is known as one of the causes of angina pectoris and sudden death and is an important clinical entity that cannot be overlooked.The incidence of coronary artery anomalies is as low as 1%-2%of t... Coronary artery anomaly is known as one of the causes of angina pectoris and sudden death and is an important clinical entity that cannot be overlooked.The incidence of coronary artery anomalies is as low as 1%-2%of the general population,even when the various types are combined.Coronary anomalies are practically challenging when the left and right coronary ostium are not found around their normal positions during coronary angiography with a catheter.If there is atherosclerotic stenosis of the coronary artery with an anomaly and percutaneous coronary intervention(PCI)is required,the suitability of the guiding catheter at the entrance and the adequate back up force of the guiding catheter are issues.The level of PCI risk itself should also be considered on a caseby-case basis.In this case,emission computed tomography in the R-1 subtype single coronary artery proved that ischemia occurred in an area where the coronary artery was not visible to the naked eye.Meticulous follow-up would be crucial,because sudden death may occur in single coronary arteries.To prevent atherosclerosis with full efforts is also important,as the authors indicated admirably. 展开更多
关键词 coronary artery anomaly Single coronary artery ISCHEMIA Sudden death Percutaneous coronary intervention coronary vessel anomalies Myocardial ischemia Sudden cardiac death
下载PDF
Clinical Value of the Quantitative Flow Ratio to Predict Long-term Target Vessel Failure in Patients with In-stent Restenosis after Drug-coated Balloon Angioplasty
6
作者 Xiang-qi WU Long-bo LI +6 位作者 Wei YOU Zhi-ming WU Lei ZHAO Zhi-hui WANG Pei-na MENG Bin LIU Fei YE 《Current Medical Science》 SCIE CAS 2024年第3期561-567,共7页
Objective The study sought to investigate the clinical predictive value of quantitative flow ratio(QFR)for the long-term target vessel failure(TVF)outcome in patients with in-stent restenosis(ISR)by using drug-coated ... Objective The study sought to investigate the clinical predictive value of quantitative flow ratio(QFR)for the long-term target vessel failure(TVF)outcome in patients with in-stent restenosis(ISR)by using drug-coated balloon(DCB)treatment after a long-term follow-up.Methods This was a retrospective study.A total of 186 patients who underwent DCB angioplasty for ISR in two hospitals from March 2014 to September 2019 were enrolled.The QFR of the entire target vessel was measured offline.The primary endpoint was TVF,including target vessel-cardiac death(TV-CD),target vessel-myocardial infarction(TV-MI),and clinically driven-target vessel revascularization(CD-TVR).Results The follow-up time was 3.09±1.53 years,and 50 patients had TVF.The QFR immediately after percutaneous coronary intervention(PCI)was significantly lower in the TVF group than in the no-TVF group.Multivariable Cox regression analysis indicated that the QFR immediately after PCI was an excellent predictor for TVF after the long-term follow-up[hazard ratio(HR):5.15×10−5(6.13×10−8−0.043);P<0.01].Receiver-operating characteristic(ROC)curve analysis demonstrated that the optimal cut-off value of the QFR immediately after PCI for predicting the long-term TVF was 0.925(area under the curve:0.886,95%confidence interval:0.834–0.938;sensitivity:83.40%,specificity:88.00;P<0.01).In addition,QFR≤0.925 post-PCI was strongly correlated with the TVF,including TV-MI and CD-TVR(P<0.01).Conclusion The QFR immediately after PCI showed a high predictive value of TVF after a long-term follow-up in ISR patients who underwent DCB angioplasty.A lower QFR immediately after PCI was associated with a worse TVF outcome. 展开更多
关键词 percutaneous coronary intervention in-stent restenosis target vessel failure quantitative flow ratio
下载PDF
Correlation of neutrophil to lymphocyte ratio to severity of coronary artery disease and in-hospital clinical outcomes in patients with acute coronary syndrome: A prospective observational study
7
作者 Vinodhkumar Kandibendla GThiruvikrama Prakash +1 位作者 Subash Chandra Bose Prafull Dhewle 《Journal of Acute Disease》 2024年第1期14-19,共6页
Objective:To explore correlation of neutrophil-to-lymphocyte ratio(NLR)to severity of coronary artery disease(CAD)and in-hospital clinical outcomes in patients with acute coronary syndrome(ACS).Methods:In this prospec... Objective:To explore correlation of neutrophil-to-lymphocyte ratio(NLR)to severity of coronary artery disease(CAD)and in-hospital clinical outcomes in patients with acute coronary syndrome(ACS).Methods:In this prospective and observational study,we recruited 500 patients with ACS.For all the eligible patients,demographic details were collected,and laboratory parameters were evaluated.The CAD severity was evaluated in terms of the number of involved vessels.The NLR was calculated based on neutrophils and lymphocytes and the correlation of various risk factors and severity and outcome of CAD was performed.Results:77.2%of Patients was male,and 52%of the patients aged between 55-70 years.Based on the type of ACS,396 out of 500 patients had ST-elevation myocardial infarction.An ascending trend in the white blood cell levels and NLR value was noted as the severity of the ACS increased and the highest white blood cell levels and NLR was noted among classⅣpatients.The mean NLR value among the non-survivors were higher compared to the survivors(9.52±5.72 vs.4.76±2.36;P<0.01).Receiver operating curve showed that the cut-off NLR value was 5.76 with a sensitivity of 75.0%and a specificity of 77.3%.Conclusions:The NLR can be used as an independent prognostic marker in ACS.An elevated NLR value serves as a reliable predictor for short-term complications,notably in-hospital mortality. 展开更多
关键词 Acute coronary syndrome coronary artery disease coronary vessels Hospital mortality LYMPHOCYTES NEUTROPHILS Prognosis Risk factors
下载PDF
Intracoronary thrombolysis combined with drug balloon angioplasty in a young ST-segment elevation myocardial infarction patient:A case report
8
作者 Li-Qiong She De-Kui Gao +3 位作者 Le Hong Yin Tian Hui-Zhen Wang Sheng Huang 《World Journal of Cardiology》 2024年第9期531-541,共11页
BACKGROUND The combination of acute ST-segment elevation myocardial infarction(STEMI)and gastric ulcers poses a challenge to primary percutaneous coronary intervention(PPCI),particularly for young patients.The role of... BACKGROUND The combination of acute ST-segment elevation myocardial infarction(STEMI)and gastric ulcers poses a challenge to primary percutaneous coronary intervention(PPCI),particularly for young patients.The role of drug-coated balloons(DCBs)in the treatment of de novo coronary artery lesions in large vessels remains unclear,especially for patients with STEMI.Our strategy is to implement drug balloon angioplasty following the intracoronary administration of low-dose prourokinase and adequate pre-expansion.CASE SUMMARY A 54-year-old male patient presented to the emergency department due to chest pain on June 24,2019.Within the first 3 minutes of the initial assessment in the emergency room,the electrocardiogram(ECG)showed significant changes.There was atrial fibrillation with ST-segment elevation.Subsequently,atrial fibrillation terminated spontaneously and reverted to sinus rhythm.Soon after,the patient experienced syncope.The ECG revealed torsades de pointes ventricular tachycardia.A few seconds later,it returned to sinus rhythm.High-sensitivity tropon in I was normal.The diagnosis was acute STEMI.Emergency coronary angiography revealed subtotal occlusion with thrombus formation in the proximal segment of the left anterior descending artery.Considering the patient's age and history of peptic ulcer disease,after the intracoronary injection of prourokinase,percutaneous transluminal coronary angioplasty and cutting balloon angioplasty were conducted for thorough preconditioning,and paclitaxel drug-eluting balloon angioplasty was performed without any stents,achieving favorable outcomes.CONCLUSION A PPCI without stents may be a viable treatment strategy for select patients with STEMI,and further research is warranted. 展开更多
关键词 STsegment elevation myocardial infarction Recombinant human prourokinase De novo coronary lesion Large vessels Drug-eluting balloon angioplasty Case report
下载PDF
The effectiveness and safety of the RESTORE R drug-eluting balloon versus a drug-eluting stent for small coronary vessel disease: study protocol for a multi-center, randomized, controlled trial 被引量:5
9
作者 Yi-Da TANG Shu-Bin QIAO +16 位作者 Xi SU Yun-Dai CHEN Ze-Ning JIN Hui CHEN Biao XU Xiang-Qing KONG Wen-Yue PANG Yong LIU Zai-Xin YU Xue LI Hui LI Yan-Yan ZHAO Wei LI Jian TIAN Chang-Dong GUAN Bo XU Run-Lin GAO 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2018年第7期469-475,共7页
bjective Small coronary vessel disease (disease affecting coronary vessels with main branch diameters of 〈 2.75 mm) is a common and intractable problem in percutaneous coronary intervention (PCI). This study was ... bjective Small coronary vessel disease (disease affecting coronary vessels with main branch diameters of 〈 2.75 mm) is a common and intractable problem in percutaneous coronary intervention (PCI). This study was designed to test the theory that the effectiveness and safety of drug-eluting balloons for the treatment of de novo lesions in small coronary vessels are non-inferior to those of drug-eluting stents. Methods We designed a prospective, multicenter, randomized, controlled clinical trial aiming to assess the effectiveness and safety of the RESTORE R (Cardionovum, Bonn, Germany) drug-eluting balloon (DEB) versus the RESOLUTE R (Medtronic, USA) drug-eluting stent (DES) in the treatment of small coronary vessel disease. This trial started in August 2016. A total of 230 patients with a reference vessel diameter (RVD) 〉 2.25 mm and 〈 2.75 mm were randomly assigned to treatment with a DEB or a DES at a 1:1 ratio. The study was also designed to enroll 30 patients with an RVD 〉 2.00 mm and 〈 2.25 mm in the tiny vessel cohort. Results The key baseline data include demographic characteristics, relative medical history, baseline angiographic values and baseline procedural characteristics. The primary endpoint is in-segment diameter stenosis at nine months after the index procedure. Secondary endpoints include acute success, all-cause death, myocardial infarction, target vessel revascularization, target lesion revascularization and stent thrombosis. Conclusions The study will evaluate the clinical efficacy, angiographic outcomes, and safety of DEBs compared to DESs in the treatment of de novo coronary artery lesions in small vessels. 展开更多
关键词 Drag eluting balloon Percutaneous coronary intervention Small vessel disease
下载PDF
Nine-year clinical outcomes of drug-eluting stents vs. bare metal stents for large coronary vessel lesions 被引量:1
10
作者 Dong YIN Jia LI +6 位作者 Yue-Jin YANG Yang WANG Yan-Yan ZHAO Shi-Jie YOU Shu-Bin QIAO Bo XU Ke-Fei DOU 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第1期35-41,共7页
Objectives To evaluate the very long-term safety and effectiveness of drug-eluting stents (DES) compared to bare-metal stents (BMS) for patients with large coronary vessels. Methods From April 2004 to October 2006... Objectives To evaluate the very long-term safety and effectiveness of drug-eluting stents (DES) compared to bare-metal stents (BMS) for patients with large coronary vessels. Methods From April 2004 to October 2006, 2407 consecutive patients undergoing de novo lesion percutaneous coronary intervention with reference vessel diameter greater than or equal to 3.5 mm at Fu Wai Hospital in Beijing, China, were prospectively enrolled into this study. We obtained 9-year clinical outcomes including death, myocardial infarction (MI), thrombosis, target lesion revascularization (TLR), target vessel revascularization (TVR), and major adverse cardiac events (MACE, the composite of death, MI, and TVR). We performed Cox's proportional-hazards models to assess relative risks of all the outcome measures after propensity match. Results After propensity scoring, 514 DES-treated patients were matched to 514 BMS-treated patients. The patients treated with BMS were associated with higher risk ofTLR (HR: 2.55, 95%CI: 1.520-4.277, P = 0.0004) and TVR (HR: 1.889, 95%CI: 1.185-3.011, P = 0.0075), but the rates of death/MI and MACE were not statistically different. All Academic Research Consortium definition stent thrombosis at 9-year were comparable in the two groups. Conclusions During long-term follow-up through nine years, use of DES in patients with large coronary arteries was still associated with significant reductions in the risks of TLR and TVR. 展开更多
关键词 Bare metal stent Drug-eluting stent Large coronary artery REVASCULARIZATION Target vessel
下载PDF
Value of the 6 minute walk test in predicting multi vessel coronary arterial disease 被引量:1
11
作者 Ruvan Ekanayaka Yasindu Waniganayake 《Open Journal of Internal Medicine》 2013年第2期42-49,共8页
The 6 minute walk test (6MWT) is well established in the clinical assessment of heart failure, pulmonary hypertension and COPD. Its value as a submaximal stress test in the risk stratification of chronic stable ischae... The 6 minute walk test (6MWT) is well established in the clinical assessment of heart failure, pulmonary hypertension and COPD. Its value as a submaximal stress test in the risk stratification of chronic stable ischaemic syndromes is as yet not validated. 95 patients undergoing coronary angiography for assessment of chronic stable angina performed the 6MWT according to a modified protocol. The gamma correlation test indicated a moderately significant relationship between ECG changes plus symptoms at the end of the 6MWT and multi vessel coronary arterial disease. The T wave changes showed no significant correlation. Hence the 6MWT is a useful tool in the risk stratification of stable ischaemic syndromes which can be safely performed in a general ward prior to hospital discharge. It would be a useful preliminary test before planning a programme of cardiac rehabilitation. 展开更多
关键词 coronary ANGIOGRAM 6 MINUTE WALK Test MULTI vessel coronary Disease
下载PDF
Clinical Outcomes in Patients Undergoing Triple-Vessel Angioplasty for Symptomatic Coronary Artery Disease
12
作者 Ashraf Safiya Manzil Jithu Sam Rajan Venkatesh Radhakrishnan 《International Journal of Clinical Medicine》 2015年第10期746-752,共7页
Current treatment strategies for multi-vessel coronary artery disease include either coronary artery bypass surgery or percutaneous coronary intervention with stenting. The present study evaluates the morbidity and mo... Current treatment strategies for multi-vessel coronary artery disease include either coronary artery bypass surgery or percutaneous coronary intervention with stenting. The present study evaluates the morbidity and mortality among coronary artery disease patients undergoing triple-vessel angioplasty. This prospective record based descriptive study was carried out in Medical College, Pariyaram, Kannur, Kerala;a tertiary care cardiac centre in South India. Fifty consecutive patients who underwent angioplasty of one or more lesions in each of the three major coronary arteries from May 2010 to July 2012 were included in the study. The study describes the clinical profile of the patients and a moderate term clinical follow-up to reassess the symptoms, functional status and left ventricular function by history, electrocardiogram, echocardiogram, and treadmill test. Mortality and morbidity were considered as end-points of the study. Event-free survival rate was 94% at a mean follow-up of 20 months. Overall 98% continued success was obtained with triple-vessel angioplasty. Triple-vessel angioplasty is a safe and effective therapy as an alternative to surgical revascularization in selected patients with triple-vessel coronary artery disease. 展开更多
关键词 coronary Artery Disease REVASCULARIZATION STENTS Triple-vessel ANGIOPLASTY
下载PDF
Topological distance-constrained feature descriptor learning model for vessel matching in coronary angiographies
13
作者 Xiaojiao SONG Jianjun ZHU +2 位作者 Jingfan FAN Danni AI Jian YANG 《Virtual Reality & Intelligent Hardware》 2021年第4期287-301,共15页
Background Feature matching technology is vital to establish the association between virtual and real objects in virtual reality and augmented reality systems.Specifically,it provides them with the ability to match a ... Background Feature matching technology is vital to establish the association between virtual and real objects in virtual reality and augmented reality systems.Specifically,it provides them with the ability to match a dynamic scene.Many image matching methods,of which most are deep learning-based,have been proposed over the past few decades.However,vessel fracture,stenosis,artifacts,high background noise,and uneven vessel gray-scale make vessel matching in coronary angiography extremely difficult.Traditional matching methods perform poorly in this regard.Methods In this study,a topological distance-constrained feature descriptor learning model is proposed.This model regards the topology of the vasculature as the connection relationship of the centerline.The topological distance combines the geodesic distance between the input patches and constrains the descriptor network by maximizing the feature difference between connected and unconnected patches to obtain more useful potential feature relationships.Results Matching patches of different sequences of angiographic images are generated for the experiments.The matching accuracy and stability of the proposed method is superior to those of the existing models.Conclusions The proposed method solves the problem of matching coronary angiographies by generating a topological distance-constrained feature descriptor. 展开更多
关键词 vessel matching Deep learning Feature descriptor coronary angiographies Geodesic distance Topological distance-constrained
下载PDF
中性粒细胞/淋巴细胞比值对冠状动脉粥样硬化性心脏病三支病变PCI术后患者预后的判断价值
14
作者 朱揆 沈德新 +9 位作者 赵江涛 秦奋 陈晓伟 于凤仪 吕炎 杨宇 秦臻 高佳敏 陶海龙 唐俊楠 《郑州大学学报(医学版)》 CAS 北大核心 2024年第5期673-677,共5页
目的:探讨中性粒细胞/淋巴细胞比值(NLR)在冠状动脉粥样硬化性心脏病(CAD)三支病变患者经皮冠状动脉介入术(PCI)术后预后评估中的价值。方法:回顾性收集2019年6月1日至2023年10月31日郑州大学第一附属医院收治并接受PCI的CAD三支病变患... 目的:探讨中性粒细胞/淋巴细胞比值(NLR)在冠状动脉粥样硬化性心脏病(CAD)三支病变患者经皮冠状动脉介入术(PCI)术后预后评估中的价值。方法:回顾性收集2019年6月1日至2023年10月31日郑州大学第一附属医院收治并接受PCI的CAD三支病变患者的临床资料,根据NLR中位数分为高NLR组(n=209)和低NLR组(n=208),绘制Kaplan-Meier风险曲线,采用Cox回归分析NLR与不良结局的关系。结果:在完全调整模型中,NLR对于全因性死亡和主要不良心血管事件的HR(95%CI)分别为1.057(1.021~1.092)和1.031(1.004~1.055),而高NLR组的HR(95%CI)分别为2.730(1.244~6.009)和1.883(1.171~3.033)。NLR对于全因性死亡和主要不良心血管事件的曲线下面积(95%CI)、敏感度、特异度分别为0.823(0.782~0.863)、0.886、0.312和0.750(0.658~0.842)、0.692、0.324,具有良好的预测价值。结论:NLR可作为CAD三支病变患者PCI术后预后的可靠预测指标。 展开更多
关键词 冠状动脉粥样硬化性心脏病三支病变 经皮冠状动脉介入术 预后 中性粒细胞/淋巴细胞比值
下载PDF
药物涂层球囊与雷帕霉素洗脱支架治疗冠状动脉小血管病变患者的效果比较 被引量:1
15
作者 仇庆华 黄兰薰 +1 位作者 常青 郭艾武 《中国民康医学》 2024年第5期153-155,共3页
目的:比较药物涂层球囊与雷帕霉素洗脱支架治疗冠状动脉小血管病变患者的效果。方法:选取2021年3月至2022年2月该院收治的60例冠状动脉小血管病变患者进行前瞻性研究,依据随机数字表法将其分为对照组与研究组各30例。两组均接受经皮冠... 目的:比较药物涂层球囊与雷帕霉素洗脱支架治疗冠状动脉小血管病变患者的效果。方法:选取2021年3月至2022年2月该院收治的60例冠状动脉小血管病变患者进行前瞻性研究,依据随机数字表法将其分为对照组与研究组各30例。两组均接受经皮冠状动脉介入治疗,对照组植入雷帕霉素洗脱支架,研究组使用药物涂层球囊治疗,术后随访1年。比较两组术前、术后即刻、术后1年时病变血管最小管腔直径(MLD)和狭窄程度,晚期管腔丢失情况以及并发症发生率。结果:术后即刻,两组MLD均大于术前,狭窄程度均低于术前,但组间比较差异均无统计学意义(P>0.05);术后1年,两组MLD均小于术后即刻,狭窄程度均高于术后即刻,但研究组MLD大于对照组,狭窄程度低于对照组,差异有统计学意义(P<0.05);术后1年,研究组晚期管腔丢失小于对照组,差异有统计学意义(P<0.05);研究组并发症发生率为13.33%(4/30),低于对照组的36.67%(11/30),差异有统计学意义(P<0.05)。结论:药物涂层球囊治疗冠状动脉小血管病变患者近期疗效与雷帕霉素洗脱支架相当,但远期疗效更好,术后1年时MLD更大、狭窄程度更低,可减少晚期管腔丢失,降低支架内血栓形成、再狭窄等并发症发生率。 展开更多
关键词 雷帕霉素 药物洗脱支架 药物涂层球囊 冠状动脉小血管病变 再狭窄 远期疗效
下载PDF
先天性右单支冠状动脉畸形并第三冠状动脉1例
16
作者 林裕霖 陈漪 +2 位作者 杨桂汉 凌文峰 杨志企 《中国介入影像与治疗学》 北大核心 2024年第10期642-642,共1页
患者女,69岁,反复活动后心前区压榨样疼痛半年、加重3天,持续1 h后逐渐缓解;否认其他特殊病史。查体未见明显异常。24 h动态心电图显示偶发多源房性期前收缩、部分连发伴反复短阵房性心动过速,偶发室性期前收缩伴短阵室性心动过速。实... 患者女,69岁,反复活动后心前区压榨样疼痛半年、加重3天,持续1 h后逐渐缓解;否认其他特殊病史。查体未见明显异常。24 h动态心电图显示偶发多源房性期前收缩、部分连发伴反复短阵房性心动过速,偶发室性期前收缩伴短阵室性心动过速。实验室检查:高敏肌钙蛋白-Ⅰ0.07 ng/ml,高敏C反应蛋白2.27mg/L。 展开更多
关键词 冠状血管 先天性畸形 CT血管成像
下载PDF
Auto-kV技术联合AI深度学习算法(Clear Infinity)在冠脉“精准”双低成像中的应用
17
作者 张斌 高思喆 +1 位作者 郭文力 李雨桐 《中国临床医学影像杂志》 CAS CSCD 北大核心 2024年第4期283-287,共5页
目的:探讨Auto-kV技术联合AI深度学习算法(Clear Infinity)在冠状动脉“双低”成像中的价值。方法:连续选取62位行冠脉CTA检查者,分为A、B两组,每组31例。A组(实验组)采用Auto-kV技术扫描,O-Dose=0.7;B组(对照组)采用常规120kV扫描,O-Do... 目的:探讨Auto-kV技术联合AI深度学习算法(Clear Infinity)在冠状动脉“双低”成像中的价值。方法:连续选取62位行冠脉CTA检查者,分为A、B两组,每组31例。A组(实验组)采用Auto-kV技术扫描,O-Dose=0.7;B组(对照组)采用常规120kV扫描,O-Dose=1.0。A组对比剂用量依据Auto-kV技术给定管电压:140kV-0.9mL/kg;120kV-0.8mL/kg;100kV-0.7mL/kg;80 kV-0.6 mL/kg;70 kV-0.5 mL/kg;60 kV-0.4 mL/kg,B组对比剂用量统一为0.8 mL/kg。对比剂注射速率=对比剂用量/12 s。将A组原始数据采用迭代重建算法(Clear View)及AI重建算法(Clear Infinity)重建出两组图像,分别命名为A1组和A2组。迭代及AI算法的权重均设定为70%。B组原始数据采用滤波反投影法(FBP)重建。采用统计学分析图像质量、碘负荷及辐射剂量的差异。结果:A1、A2组图像冠脉各节段内CT值均高于B组,差异均有统计学意义(P均<0.001)。A1、A2组的噪声显著低于B组,差异有统计学意义(P均<0.001)。A1、A2组的信噪比及对比噪声比显著高于B组,差异有统计学意义(P均<0.001)。A、B两组间CTDI、DLP、ED及碘负荷的差异均有统计学意义(P均<0.001),A组的碘负荷及辐射剂量均显著低于B组。主观评测中三组间对比度无统计学差异;A1、A2组的主观噪声及诊断置信度优于B组,有统计学意义,A1、A2组间没有统计学意义;在锐利度及细节显示上三组间均有统计学意义,且A2组优于A1组优于B组。结论:Auto-kV技术联合AI深度学习算法(Clear Infinity)应用于冠状动脉CTA中可实现个体化扫描,显著降低对比剂用量及辐射剂量,并保证图像质量。 展开更多
关键词 冠状血管 体层摄影术 X线计算机
下载PDF
高尿酸血症与支架内再狭窄及再次介入治疗的相关性研究
18
作者 江尕学 朱友琦 +2 位作者 徐吉喆 张博 白明 《中国卫生标准管理》 2024年第10期91-94,共4页
目的 探讨高尿酸血症与经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后支架内再狭窄(in-stent restenosis,ISR)及支架内狭窄再介入治疗的相关性。方法 选取2021年1—12月在兰州大学第一医院行PCI且术后1年复查冠状... 目的 探讨高尿酸血症与经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后支架内再狭窄(in-stent restenosis,ISR)及支架内狭窄再介入治疗的相关性。方法 选取2021年1—12月在兰州大学第一医院行PCI且术后1年复查冠状动脉造影的480例急性冠脉综合征(acute coronary syndrome,ACS)患者。按照尿酸水平分为2组,高尿酸血症组(n=91)和非高尿酸血症组(n=389)。对比2组基线资料及首次造影结果,对比1年随访复查造影时ISR发生率及ISR需再次血运重建率。采用多因素分析ISR及ISR再次血运重建的影响因素。结果 高尿酸血症组男性比例低于非高尿酸血症组,年龄大于非高尿酸血症组,且血清肌酐水平高于非高尿酸血症组(P<0.05)。高尿酸血症组冠脉病变多为三支病变,随访1年时ISR发生率为21.98%,ISR需再次PCI发生率为17.58%,均高于非高尿酸血症组的10.28%、7.45%(P<0.05)。多因素回归分析显示,高尿酸血症不能独立预测ISR发生。结论 ACS患者合并高尿酸血症时冠脉病变较重,高尿酸血症可增加ISR发生率及再次血运重建率,但无法独立预测ISR发生。 展开更多
关键词 急性冠脉综合征 高尿酸血症 经皮冠状动脉介入治疗 多支病变 支架内再狭窄 血运重建
下载PDF
人工智能触发技术与传统团注追踪触发技术在冠状动脉血管成像中的对比研究
19
作者 刘杰 原典 +1 位作者 张怡存 高剑波 《中国CT和MRI杂志》 2024年第7期83-86,共4页
目的评估人工智能(AI)触发技术在冠状动脉CT血管成像(CCTA)中对血管峰值增强时间预测的准确性,并将其与传统的团注追踪技术进行比较。方法在这项前瞻性研究中,将204名连续患者连续分为两组进行CCTA扫描:以固定的5秒触发后延迟(PTD)为特... 目的评估人工智能(AI)触发技术在冠状动脉CT血管成像(CCTA)中对血管峰值增强时间预测的准确性,并将其与传统的团注追踪技术进行比较。方法在这项前瞻性研究中,将204名连续患者连续分为两组进行CCTA扫描:以固定的5秒触发后延迟(PTD)为特点的传统团注追踪技术组(A组);以患者特异性PTD为特点的AI触发技术组(B组)。所有扫描参数(管电压100kV结合CARE Dose 4D的智能管电流调节技术)和对比剂注射方案(320mgI/mL;0.7mL/kg)在各组之间保持一致。一位医师评估了客观图像质量,而两位医师使用Likert 5级评分法评估主观图像质量。通过双样本t检验比较各组之间的客观图像质量,同时用卡方检验比较主观评分。结果两组均有102名患者(A组平均年龄50±10岁;B组平均年龄51±9岁),具有可比较的基线特征。两位医师都对B组的主观图像质量进行了评分(P<0.001)。B组所有冠状动脉血管平均血管增强显着增高(P均<0.05)。结论与传统团注追踪技术相比,AI触发技术可以实现可靠的扫描时间,优化血管强化峰值,获得更好的CCTA图像质量。 展开更多
关键词 人工智能 冠状血管 体层摄影术 X线计算机
下载PDF
药物涂层球囊治疗冠状动脉原位病变后靶血管正性重构的多因素分析
20
作者 张帆 贾永平 《心血管康复医学杂志》 CAS 2024年第3期322-326,共5页
目的:探究影响药物涂层球囊(DCB)治疗冠状动脉原位病变后靶血管正性重构的因素。方法:回顾性分析2019年6月-2021年6月于我院行DCB治疗冠状动脉原位病变并出院后行血管内超声(IVUS)或光学相干断层成像(OCT)复查冠状动脉靶血管情况的130... 目的:探究影响药物涂层球囊(DCB)治疗冠状动脉原位病变后靶血管正性重构的因素。方法:回顾性分析2019年6月-2021年6月于我院行DCB治疗冠状动脉原位病变并出院后行血管内超声(IVUS)或光学相干断层成像(OCT)复查冠状动脉靶血管情况的130例患者的临床资料。根据冠状动脉靶血管情况,患者被分为正性重构组(57例)和负性重构组(73例),采用多因素Logistic回归分析影响冠状动脉原位病变患者DCB治疗后靶血管正性重构的因素。结果:与负性重构组比较,正性重构组男性(74.0%比89.5%)、使用棘突球囊(31.5%比49.1%)、右冠或后降支左室后支病变(11.0%比28.1%)、年收入>10万元(19.2%比35.1%)、运动频数≥5次/周(6.8%比64.9%)比例、随访期间最小管腔直径[(2.22±0.87)mm比(2.95±0.34)mm]、住院费用[70218.42(51461.18,96114.17)元比91003.74(61930.16,116948.25)元]显著升高,吸烟史(67.1%比38.6%)和睡眠质量差(86.3%比22.8%)比例显著降低,P<0.05或<0.01。多因素Logistic回归分析显示运动频次≥3次/周、睡眠质量好和棘突/切割球囊的使用是此类患者DCB治疗后靶血管正性重构的独立保护因素(OR=0.014~0.097,P均<0.01),而吸烟史是其独立危险因素(OR=3.970,P=0.047)。结论:吸烟史是药物涂层球囊治疗冠状动脉原位病变后靶血管正性重构的独立危险因素,而运动频次≥3次/周、睡眠质量好和棘突/切割球囊的使用是其独立保护因素。 展开更多
关键词 冠状动脉疾病 药物涂层球囊 靶血管重构 影响因素
下载PDF
上一页 1 2 68 下一页 到第
使用帮助 返回顶部