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Arterial hypertension and electrocardiographic diagnosis of left ventricular hypertension in the group of geriatric patients with coronary heart disease living in the far north 被引量:2
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作者 Natalya Arkhipova Elena Popova Aleksandr Ariev 《Health》 2013年第6期122-127,共6页
As a result of research, high prevalence of arterial hypertension has been identified in the group of patients with coronary heart disease aged 60 and older. Most often, occurring form of arterial hypertension among g... As a result of research, high prevalence of arterial hypertension has been identified in the group of patients with coronary heart disease aged 60 and older. Most often, occurring form of arterial hypertension among geriatric patients is isolated systolic arterial hypertension (ISAH). The comparison of two ethnic groups of the population has showed higher levels of systolic and diastolic blood pressure (SBP and DBP) in the group of patients of non-indigenous nationality, rather than Yakut patients. Correlation was recorded in the group of non-indigenous patients as they age. Significant increase in the level of SBP was identified in the group of senile and long-livers than in the elderly. Detection of ECG signs of LVH showed the lowest specificity of Cornell voltage criterion comparing to Sokolow-Lyon criterion with its more often occurrence. ECG-signs of left ventricle hypertrophy are significantly more often established by Sokolow-Lyon criterion for men, Cornell voltage—for women. Correlation has been found between the presence of LVH and combination of Cornell voltage criterion with both Gubner-Ungerleider and Sokolow-Lyon criteria. 展开更多
关键词 Arterial HYPERTENSION coronary heart disease GERIATRIC Age NON-INDIGENOUS and Yakut patients Electrocardiographic Criteria of Left VENTRICLE HYPERTROPHY
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Relationship between the Self-Efficacy and Mental Health of Elderly Patients with Coronary Heart Disease in Rural Hebei Province 被引量:1
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作者 Ling-ling Li Jing Wang +7 位作者 Yi-Lin Wang Jin Jiao Jia Meng Yan Su Xiao-Jing Du Yan Wang Gui-Ping Sun Yan-Ling Li 《Proceedings of Anticancer Research》 2022年第2期14-19,共6页
Objective:To investigate the self-efficacy and mental health of elderly patients with coronary heart disease(CHD)in rural Hebei Province as well as to analyze the relationship between them.Methods:From June 2021 to De... Objective:To investigate the self-efficacy and mental health of elderly patients with coronary heart disease(CHD)in rural Hebei Province as well as to analyze the relationship between them.Methods:From June 2021 to December 2021,480 elderly patients with CHD from rural areas,who had been discharged by the Department of Cardiology from three tertiary hospitals in three cities with different economic levels in Hebei Province for more than a year,were selected as the research subjects.The general self-efficacy scale(GSES)and symptom self-rating scale(SCL-90)were used to investigate the self-efficacy and mental health of these patients.SPSS 25.0 was used for data analysis.Results:The total mean self-efficacy score of elderly patients with CHD in rural Hebei Province was 17.18±4.68,which is lower than the international norm(t=-32.067,P=0.000)and the national norm(t=-28.783,P=0.000);the total average SCL-90 score was 148.64±55.13,which is higher than the national norm for adults and the reference norm for ordinary elderly people;except for hostility and psychosis,the other dimensions were significantly higher than the national norm for adults(P<0.05);except for psychosis,the other dimensions were significantly higher than the reference norm for ordinary elderly people(P<0.05);the self-efficacy score was found to be negatively correlated with the total SCL-90 score and the score for each dimension(P<0.05).Conclusion:Elderly CHD patients with higher self-efficacy in rural Hebei Province have higher mental health level.It is suggested that the mental health of elderly patients with CHD in rural areas can be improved by improving their self-efficacy. 展开更多
关键词 RURAL Elderly patients coronary heart disease SELF-EFFICACY Mental health
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A Readmission Risk Prediction Model for Elderly Patients with Coronary Heart Disease 被引量:1
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作者 Yan-Ling Li Xiao-Hui Qi +8 位作者 Yi-Lin Wang Jin Jiao Jing Li Jia Meng Yan Su Xiao-Jing Du Yan Wang Gui-Ping Sun Hui Wang 《Journal of Clinical and Nursing Research》 2022年第2期126-133,共8页
Objective:To analyze the independent risk factors and establish a risk prediction model by investigating the readmission of elderly patients with coronary heart disease(CHD)within 1 year after discharge.Methods:A tota... Objective:To analyze the independent risk factors and establish a risk prediction model by investigating the readmission of elderly patients with coronary heart disease(CHD)within 1 year after discharge.Methods:A total of 480 CHD patients,who were hospitalized in the Affiliated Hospital of Hebei University from October 2019 to December 2020,were included in this study.A general data scale,mental health status scale,the Clinical Frailty Scale,Pittsburgh Sleep Quality Index,as well as the Family Adaptability and Cohesion Evaluation Scale were used to collect data.According to the number of readmissions due to CHD within 1 year after discharge,the patients were divided into two groups:the readmission group(n=212)and the no readmission group(n=268).General data,laboratory examination indicators,frailty,mental health status,sleep status,as well as family intimacy and adaptability were compared between the two groups.Logistic regression was used to analyze the independent risk factors for the readmission of these patients,and R software was used to construct a line diagram model for predicting readmission of elderly patients with CHD.Results:Five factors including body mass index(OR=1.045),low density lipoprotein(OR=1.123),frailty(OR=1.946),mental health(OR=1.099),as well as family intimacy and adaptability(OR=0.928)were included to construct the risk prediction model for the readmission of elderly patients with CHD within 1 year after discharge.The ROC curve showed that the area under the curve for predicting readmission of elderly patients with CHD was 0.816;Hosmer-Lemeshow goodness of fit test showed X2=1.456 and P=0.989;the maximum Youden index corresponding to the predicted value of risk was 0.526.The results showed that the model could accurately predict the risk of readmission in elderly patients with CHD within 1 year after discharge.Conclusion:This study constructed a line diagram model based on five independent risk factors of the readmission of elderly patients with CHD:body mass index,low density lipoprotein,frailty,mental health status,as well as family intimacy and adaptability.This model has good discrimination,accuracy,and predictive efficiency,providing reference for the early prevention and intervention of readmission in elderly patients with CHD recurrence. 展开更多
关键词 Elderly patients coronary heart disease(CHD) READMISSION Risk prediction model
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Feasibility of percutaneous coronary intervention via transulnar artery approachin selective patients with coronary heart disease
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作者 傅向华 马宁 +10 位作者 刘君 吴伟力 王燕 郭靖涛 苗青 李世强 谷新顺 姜云发 李亮 郝国桢 张斌 《介入放射学杂志》 CSCD 2003年第S1期-,共2页
Objective To probe the clinic feasibility of percutaneous coronary intervention(PCI) via transulnar artery approach (PCI TRU).Methods Fourty patients with unstable ischemic manifestation(male 34,female 6;age 59.3 ... Objective To probe the clinic feasibility of percutaneous coronary intervention(PCI) via transulnar artery approach (PCI TRU).Methods Fourty patients with unstable ischemic manifestation(male 34,female 6;age 59.3 ±9.10 years)whose radial artery of right hand was thin with a weak pulse that was not suitable to transradial artery PCI while whose ulnar artery was thick with a strong pulse based on their larger diameter in ulnar artery as compared with those in radial artery ( 3.30 ±0.22mm vs 2.43 ±0.33 mm, P <0.05 ) by the investigation of vessel echography,but revesered Allen’s test for radial and ulnar artery was positive,were selected as the subjects for PCI TRU. The radio of ulnar artery versus radial artery was 1.35:1.00 and the time of Allen’s test in ulnar artery side was shorter than that in radial artery side ( 2.70 ±0.36 s vs 4.68 ±0.52s , P <0.05 ) before PCI. The efficiency of PCI TRU was evaluated. The time of manipulative duration for each procedure of PCI TRU was recorded. The time of Allen’s test, luminal diameter (mm) , cross area of vessel lumin (mm 2), blood velocity (Vs max), blood resistance (RI) in ulnar artery and radial artery and the level of blood oxygen in finger (PaO 2、SatO 2) were measured and recorded , respectively , as well were compared quantitatively before and after 1 month of procedure . Results Fourty eight lesion segments of 42 vessels in all patients were angioplasticized successfully via TRU by 6F guiding catheter including 23 segments of type B1 , 14 segments of type B2 and 11 segments of type C. PCI TRU in all of 40 patients was performed successfully. Fourty eight stents were implanted including 2 lesions of intrastent restenosis angioplasticized with cutting balloon technique before re stenting . The average time of manipulative duration of guiding catheters engaging in osicum of target coronary, crossing the vessel lesions of guidewire, dilatation and implantation of stents,and under X ray fluoroscopy were 4.30 ±0.59 min , 2.52 ±0.40min , 2.66 ±0.40 min ,and 25.9 ±0.49 min , respectively, and the total time of the whole procedure was 56.6 ±14.8 min . When the ulnar introducer was taken off, the access site in ulnar artery was suppressed by tourniquet with no bleeding in the access site and no limitation of physical activation under maintaining infusion of heparin immediately after procedure . There was no significant change in the diameter of ulnar artery and the time of Allen’s test after 1 month of PCI procedure as compared with those before procedure ( 3.22 ±0.48mm vs 3.26 ±0.22 mm , P >0.05 ; 2.96 ±0.98 s vs 2.72 ±0.47 s , P >0.05 ). No significant change was found in the parameters of blood velocity , cross area of vessel lumin, blood resistance and the level of blood oxygen in finger after 1 month of PCI procedure. The average total hospital stay was 5.21 ±0.43 days. Following up 1 month, no complications such as occlusion of ulnar artery, abnormal sensitivity and movement disability were found in right hands in all patients.Conclusions The ulnar artery might be selected as one approach of antebrachial artery for PCI in the patients with coronary heart disease whose radial artery was difficulty as access vessels of PCI, while reversed Allen’s test for radial and ulnar artery are positive and the luminal diameter of ulnar artery was larger than that of radial artery. 展开更多
关键词 河北医科大学第二医院 Feasibility of percutaneous coronary intervention via transulnar artery approachin selective patients with coronary heart disease of with
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Change and significance of fibrinolysis in coronary heart disease patients with angina pactoris
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作者 MA Jian-lin,LIN Jing,SU Zhe-tan (Department of Cardiovascular Disease of Hainan Provincial People’s Hospital,Haikou 570311) 《岭南心血管病杂志》 2011年第S1期74-74,共1页
Objectives To study change and the clinical significance of fibrinolysis in coronary heart disease(CHD) patients with angina pactoris(AP).Methods Levels of plas-min plasminogen activator inhibitor-1(PAI-1),tissue-type... Objectives To study change and the clinical significance of fibrinolysis in coronary heart disease(CHD) patients with angina pactoris(AP).Methods Levels of plas-min plasminogen activator inhibitor-1(PAI-1),tissue-type plasminogen activator(t-PA),fibrinogen(FIB) in 110 CHD patients with AP and 20 normal cases as control group were analyzed in the same ways.Results Levels of PAI-1,FIB in CHD patients with AP were significantly higher than those in control cases,and those of t-PA were significantly lower than control cases;Levels of PAI-1,FIB in UA patients with UA heart events were significantly higher than those in patients with SA,and those of t-PA were significantly lower than patients with SA;Levels of PAI-1,FIB in patients with AP events were significantly higher than those in patients without AP events,and those of t-PA were significantly lower than patients without AP events.Conclusions There was abnormal of fibrinolysis function in CHD patients with AP, specially in patients with UA or with AP events,the abnormal of fibrinolysis might be play an important rule in coronary heart disease(CHD) patients with angina pactoris. 展开更多
关键词 CHD PAI than Change and significance of fibrinolysis in coronary heart disease patients with angina pactoris FIB
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Clinical efficacy and significance of serum fibroblast growth factor-21 and ghrelin in the treatment of type 2 diabetes complicated with coronary heart disease with integrated traditional Chinese and western medicine
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作者 Su Gao Xue Tian +1 位作者 Wei-Na Jiang Yao Ma 《Journal of Hainan Medical University》 2018年第22期13-17,共5页
Objective: To treat the patients with type 2 diabetes mellitus complicated with coronary heart disease, to explore the clinical efficacy and mechanism of conventional western medicine combined with Yiqi Yangyin Huoxue... Objective: To treat the patients with type 2 diabetes mellitus complicated with coronary heart disease, to explore the clinical efficacy and mechanism of conventional western medicine combined with Yiqi Yangyin Huoxue herbs, and to detect the level of serum fibroblast growth factor-21 (FGF-21) and Ghrelin. Changes and significance. Methods: A randomized control method was used to collect 100 patients with type 2 diabetes mellitus complicated with coronary heart disease who were diagnosed and treated in our hospital from March 2015 to March 2018.They were randomly divided into two groups according to the random number table method: 50 patients separately. The patients in the control group were treated with conventional western medicine and basic treatment;the observation group was treated with the addition and subtraction of traditional Chinese medicine formulas on the basis of the control group;the clinical curative effect was evaluated after two months of treatment, and the treatment efficiency and scores of traditional Chinese medicine symptoms were observed in the two groups. Basic laboratory indicators were improved, and serum levels of FGF-21 and Ghrelin in patients were measured and the difference between the results of the tests was compared with the condition and efficacy. Results: After treatment, the total effective rate of the observation group (86.0%) was significantly higher than that of the control group (68.0%) (P<0.05), suggesting that the combination of Chinese and Western medicine treatment can significantly improve the clinical efficacy;before treatment,there is no difference between the two groups of Chinese medicine symptom scores (P>0.05). After treatment, the symptom scores of the two groups were significantly improved after treatment (P<0.05). The observation group was better among the two groups (P<0.05).After treatment, the basic biochemical indicators were improved. The observation group was better than the control group (P<0.05);Serum FGF-21 levels were significantly lower in both groups after treatment (P<0.05), and Ghrelin levels were significantly increased. There was a statistically significant difference between the two groups (P<0.05). Conclusion: The use of conventional western medicine in combination with Yiqi Yangyin Huoxue Chinese medicine for the treatment of type 2 diabetes mellitus patients with coronary heart disease can significantly improve the clinical efficacy, effectively promote the improvement of symptoms, and can be used in clinical work through serum FGF-21, Ghrelin levels combined detection of the value of Abnormal changes to predict the severity of type 2 diabetes mellitus with coronary heart disease severity and treatment effect should be widely used in clinical diagnosis and treatment. 展开更多
关键词 Type 2 diabetes mellitus complicated coronary heart disease INTEGRATED TRADITIONAL Chinese and western medicine FGF-21 GHRELIN
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Risk of cardiovascular,cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease 被引量:58
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作者 Stefano Ballestri Amedeo Lonardo +3 位作者 Stefano Bonapace Christopher D Byrne Paola Loria Giovanni Targher 《World Journal of Gastroenterology》 SCIE CAS 2014年第7期1724-1745,共22页
Non-alcoholic fatty liver disease(NAFLD)has emerged as a public health problem of epidemic proportions worldwide.Accumulating clinical and epidemiological evidence indicates that NAFLD is not only associated with live... Non-alcoholic fatty liver disease(NAFLD)has emerged as a public health problem of epidemic proportions worldwide.Accumulating clinical and epidemiological evidence indicates that NAFLD is not only associated with liver-related morbidity and mortality but also with an increased risk of coronary heart disease(CHD),abnormalities of cardiac function and structure(e.g.,left ventricular dysfunction and hypertrophy,and heart failure),valvular heart disease(e.g.,aortic valve sclerosis)and arrhythmias(e.g.,atrial fibrillation).Experimental evidence suggests that NAFLD itself,especially in its more severe forms,exacerbates systemic/hepatic insulin resistance,causes atherogenic dyslipidemia,and releases a variety of pro-inflammatory,pro-coagulant and pro-fibrogenic mediators that may play important roles in the pathophysiology of cardiac and arrhythmic complications.Collectively,these findings suggest that patients with NAFLD may benefit from more intensive surveillance and early treatment interventions to decrease the risk for CHD and other cardiac/arrhythmic complications.The purpose of this clinical review is to summarize the rapidly expanding body of evidence that supports a strong association between NAFLD and cardiovascular,cardiac and arrhythmic complications,to briefly examine the putative biological mechanisms underlying this association,and to discuss some of the current treatment options that may influence both NAFLD and its related cardiac and arrhythmic complications. 展开更多
关键词 Non-alcoholic fatty liver disease Cardiovascular disease Cardiac complications coronary heart disease Myocardial dysfunction Valvular heart disease ARRHYTHMIAS Arrhythmic complications
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Research Progress on the Depression Status and Nursing Intervention in Patients after Percutaneous Coronary Intervention
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作者 Hui Qiang Li Li +1 位作者 Yan Hua Lin Han 《Journal of Clinical and Nursing Research》 2024年第2期33-43,共11页
Percutaneous coronary intervention(PCI)is an effective treatment method for myocardial ischemic necrosis.Postoperative depression caused by PCI stress will adversely affect the prognosis of patients.This article revie... Percutaneous coronary intervention(PCI)is an effective treatment method for myocardial ischemic necrosis.Postoperative depression caused by PCI stress will adversely affect the prognosis of patients.This article reviews the current status and influencing factors of postoperative depression after PCI and summarizes the corresponding nursing interventions,to provide a literature reference to implement effective nursing interventions for depressed patients after clinical PCI. 展开更多
关键词 coronary heart disease Percutaneous coronary intervention patients with coronary heart disease DEPRESSION Nursing interventions Research progress
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Effect of St. John's wort extract on depressive disorder in elderly patients with unstable angina
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作者 Jian Liu Zhao-wci Mcng +2 位作者 Li-yu Li Li-sha Fcng Hui Yang 《World Journal of Emergency Medicine》 SCIE CAS 2010年第1期41-44,共4页
The elderly patients with coronary heart disease (CHD) are often accompanied with depression. This study aimed to assess the effect of St. John's wort extract (SWE) on depressive disorder in elderly patients with... The elderly patients with coronary heart disease (CHD) are often accompanied with depression. This study aimed to assess the effect of St. John's wort extract (SWE) on depressive disorder in elderly patients with unstable angina pectoris. Altogether 170 patients who met the set criteria were enrolled in this prospective study. They were randomly divided into SWE group (44 patients), Deanxit group (44), psychotherapy group (42), and control group (40). The effectiveness of SWE was evaluated by reduced percentage of Hamilton depression (HAMD) scale and reduced frequency of angina pectoris attack, which were measured before and at 12 weeks after the treatment with SWE. The reduced percentages of HAMD scale were 79.5%, 56.8% and 57.1% in the SWE, Deanxit and psychotherapy groups, respectively. Compared with the control, the three groups had significant differences in the percentages (P〈0.001). The improvement after the treatment was more significant in the SWE group than in the Deanxit or psychotherapy group (P〈0,05). The improvement of angina pectoris evaluated by the Canadian Cardiac Society Classification was significantly better in the treatment groups (88.7%, 65.9%, 57.1%) than in the control group, and it was marked in the SWE group (P〈0.001). Angina pectoris attack, its frequencies, durations and electrocardiographic changes were significantly improved in the treatment groups than in the control group (F=6.05, 4.58, 5.12, P〈0.01). They are markedly improved in the SWE group (P〈0.05). SWE can improve depressive symptoms more significantly in elderly patients with unstable angina pectoris than Deanxit or psychotherapy, proving that SWE contributes to better treatment of angina attack as well. 展开更多
关键词 St. John's wort extract DEPRESSION Elderly patients coronary heart disease Unstable angina pectoris PSYCHOTHERAPY
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Thinking on Treatment of Post-reperfusion Events in Patients with Coronary Heart Disease by Integrated Traditional Chinese and Western Medicine
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作者 史载祥 《Chinese Journal of Integrative Medicine》 SCIE CAS 2007年第1期3-5,共3页
In the 1970's, promoting blood circulation to remove blood stasis (PCRS) was the main method in integrative traditional Chinese and Western medicine (ICWM) in treating acute myocardial infarction (AMI). It decr... In the 1970's, promoting blood circulation to remove blood stasis (PCRS) was the main method in integrative traditional Chinese and Western medicine (ICWM) in treating acute myocardial infarction (AMI). It decreased the case fatality rate of AMI from 30% to 13%-16% as compared with that treated by simple Western internal medical conservative treatment. Later in the 1980's, such therapeutic approaches as infarction related arterial revascularization, thrombolysis and percutaneous coronary intervention (PCI) became the most effective means in treating AMI, which could re-canalize the obstructed coronary vessels, recover the blood perfusion of myocardium, and thus to save the ischemic myocardium, diminute the infarcted size, preserve the ventricular function and improve the patient's near and long-term prognosis, with the fatality rate reduced by 5%-7%. Hence, the some-time superiority of ICWM in treating AMI was overshadowed with no more luster left. 展开更多
关键词 Thinking on Treatment of Post-reperfusion Events in patients with coronary heart disease by Integrated Traditional Chinese and Western Medicine PCI AMI CHD TIMI
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Management of chronic heart failure in the older population 被引量:26
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作者 Nahid Azad Genevieve Lemay 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2014年第4期329-337,共9页
Chronic heart failure (CHF) is the leading cause of hospitalization for those over the age of 65 and represents a significant clinical and economic burden. About half of hospital re-admissions are related to co-morb... Chronic heart failure (CHF) is the leading cause of hospitalization for those over the age of 65 and represents a significant clinical and economic burden. About half of hospital re-admissions are related to co-morbidities, polypharmacy and disabilities associated with CHF. Moreover, CHF also has an enormous cost in terms of poor prognosis with an average one year mortality of 33%–35%. While more than half of patients with CHF are over 75 years, most clinical trials have included younger patients with a mean age of 61 years. Inadequate data makes treatment decisions challenging for the providers. Older CHF patients are more often female, have less cardiovascular diseases and associated risk factors, but higher rates of non-cardiovascular conditions and diastolic dysfunction. The prevalence of CHF with reduced ejection fraction, ischemic heart disease, and its risk factors declines with age, whereas the prevalence of non-cardiac co-morbidities, such as chronic renal failure, dementia, anemia and malignancy increases with age. Diabetes and hypertension are among the strongest risk factors as predictors of CHF particularly among women with coronary heart disease. This review paper will focus on the specific consideration for CHF assessment in the older population. Management strategies will be reviewed, including non-pharmacologic, pharmacologic, quality care indicators, quality improvement in care transition and lastly, end-of-life issues. Palliative care should be an integral part of an interdiscipli-nary team approach for a comprehensive care plan over the whole disease trajectory. In addition, frailty contributes valuable prognostic in-sight incremental to existing risk models and assists clinicians in defining optimal care pathways for their patients. 展开更多
关键词 heart failure Elderly patient MANAGEMENT HYPERTENSION coronary artery disease DIABETES
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A meta-analysis of the effects of statins on serum C-reactive protein in Chinese population with coronary heart disease or hyperlipidemia 被引量:1
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作者 HAO PanPan CHEN YuGuo +3 位作者 WANG XingLi XU Feng WANG JiaLi ZHANG Yun 《Chinese Science Bulletin》 SCIE EI CAS 2009年第23期4404-4410,共7页
There is little doubt that statins reduce cardiovascular events more than what the lipid lowering effect can account for. Additional mechanisms have been postulated including the anti-inflammatory effects manifested b... There is little doubt that statins reduce cardiovascular events more than what the lipid lowering effect can account for. Additional mechanisms have been postulated including the anti-inflammatory effects manifested by reduced C-reactive protein (CRP). It is not known, however, whether statins can decrease CRP in Chinese population. The aim of this study is to investigate the effects of statins on serum CRP in Chinese patients with coronary heart disease (CHD) or hyperlipidemia. Trials were retrieved through Medline (1980 to May, 2009), bibliographies, and the author’s reference files limited to English-language articles. Data were extracted and meta-analysis was performed. Analysis showed statistically significant reduction in CRP after statin treatment (weighted mean difference [WMD] = -0.73, 95% confidence interval [CI] = [-0.80, -0.66], P < 0.00001) and lower CRP after statin treatment than non-statin routine treatment ([WMD] = -0.52, 95% CI [-0.86, -0.18], P = 0.002). In conclusion, statins significantly reduce serum CRP in Chinese population, which may contribute to statin-induced reduction in the cardiovascular risk in addition to the lipid lowering effect. 展开更多
关键词 他汀类药物 C反应蛋白 高脂血症 冠心病 血清 人口 大规模杀伤性武器 心血管疾病
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Exploration on Relationship between Syndrome Differentiation ofPhlegm Stasis Syndrome and Serum Lipoprotein EleotrophoretogramIn Patients of Senile Coronary Heart Disease
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作者 梁东辉 +4 位作者 曾昭龙 李小敏 陈允钦 钱学贤 尹炳生 《Chinese Journal of Integrative Medicine》 SCIE CAS 1999年第2期147-147,共1页
关键词 PSS Exploration on Relationship between Syndrome Differentiation ofPhlegm Stasis Syndrome and Serum Lipoprotein EleotrophoretogramIn patients of Senile coronary heart disease
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Effects of N-3 Fatty Acids on the Coronary Heart Disease Patients
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作者 李琳 李远红 余薇 《South China Journal of Cardiology》 CAS 2008年第4期179-183,共5页
Objectives To evaluate the effects of n-3 fatty acids on the coronary heart disease patients. Methods From September 2007 to March 2008, 60 patients with coronary heart disease were randomly assigned to n-3 fatty acid... Objectives To evaluate the effects of n-3 fatty acids on the coronary heart disease patients. Methods From September 2007 to March 2008, 60 patients with coronary heart disease were randomly assigned to n-3 fatty acids group (group N) and control group (group C). Both groups received standard coronary artery disease secondary prevention treatment and group N also received eicosapentaenoic acid (EPA) 1.8 g plus docosahexaenoic acid (DHA) 1.2 g per day for 12 weeks. Plasma triacylglycerols, total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and blood pressure were measured before and after the study. Results Plasma triacylglycerols, blood pressure and LDL-C level were lower in group N after n-3 fatty acids treatment while no change was found in group C (P<0.05). HDL-C level slightly increased and total cholesterol level slightly decreased after n-3 fatty acids but both change were not significant (P>0.05). Conclusions N-3 fatty acids have beneficial effects on the coronary artery disease patients. 展开更多
关键词 coronary heart disease patients n-3 fatty acids eicosapentaenoic acid docosahexaenoic acid triacylglycerols total cholesterol low-density lipoprotein cholesterol high-density lipoprotein cholesterol blood pressure
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A Pilot Study about the First Cases of Coronary Angioplasty in Democratic Republic of Congo/Kinshasa: Patient Profile
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作者 David Ipungu Gondele Eulethère Vita Kintoki +9 位作者 Yves Lubenga Georges Ngoyi Trésor Mvunzi Dominique Mupepe Nathan Buila Zéphirin Kamuanga Fahd Qureshi Aliosha Nkodila Jean Robert Rissasi Makulo Jean René M’buyamba-Kabangu 《Case Reports in Clinical Medicine》 2023年第10期371-388,共18页
Background: The objective of this pilot study was to describe clinical profile, electric, echocardiographic and angiographic caracteristics with procedural outcome of congolease patients undergoing coronarography in t... Background: The objective of this pilot study was to describe clinical profile, electric, echocardiographic and angiographic caracteristics with procedural outcome of congolease patients undergoing coronarography in the first and only one cardiac catheterization center opened in Kinshasa. Methods: An analytical cross-sectional study was carried out over a period from October 2019 (date of establishment of the first coronary angiography unit in DR Congo) to March 2021. We proceeded to a serial sampling of the consecutive cases of all the patients who have an angiographic exploration of coronary arteries. Clinical, ECG and cardiac ultrasound data were collected in all patients. The indications for the coronary angiography examination were set by differents cardiologists on the basis of repolarization troubles in the electrocardiogram, cinetic troubles in echocardiography, positive stress test and chest pain in patients with cardiovascular risq factors. Results: The serie (47 patients) was predominantly male with a sex ratio M/W of 2.6. The average age was 59.8 ± 10.5 years. Arterial hypertension (HBP) was the main risk factor (89.4%);followed by diabetes mellitus (14.9%). Chest pain was the main functional sign with an atypical character in 44.7%. The ECG showed ST segment depression (17%) and T wave inversion (17%), the anterior region being the most affected. Hypokinesia was the most common echocardiographic abnormality (34%), followed by akinesia (10.6%). The anteroseptal and apical territories were affected in 12.8%. Dilated myocardiopathy (DMC) was significantly predominant in the male sex (29.4% vs 7.7%;p = 0.011). With radial puncture as the main approach, coronary angiography was pathological in 44% revealing mono-truncal lesions. The left coronary network was the most affected: the middle inter ventricular artery (12.8%), the proximal interventricular artery (10.6%) and the proximal circonflex artery (10.6%). In multivariate logistic regression analysis, age (for age > 50 years for men and >60 years for women), arterial hypertension and dilated cardiomyopathy emerged as independent determinants of pathological coronary angiography. Transluminal angioplasty was performed in 27.7% of patients. The bypass indication was retained in 4.3% of cases and medical treatment in 68%. Conclusion: Coronary angiography was used to diagnose lesions responsible for ischemic heart disease and to treat 27.7% of patients locally. The young age of patients and limited financial resources encourage the strengthening of preventive measures against cardio vascular risq factors. 展开更多
关键词 heart disease coronary Angioplasty Patient Profile Pilot Study Democratic Republic of Congo
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Impact of subclinical hypothyroidism on clinical outcome of patients coronary heart disease undergoing percutaneous coronary intervention
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作者 WU Jiutao 《China Medical Abstracts(Internal Medicine)》 2019年第2期92-93,共2页
Objective To compare the clinical outcome of coronaryheart disease patients with normal TSH (ET) andsubclinical hypothyroidism ( SCH) after PCI. MethodsThis prospective cohort study analyzed the impact of differentlev... Objective To compare the clinical outcome of coronaryheart disease patients with normal TSH (ET) andsubclinical hypothyroidism ( SCH) after PCI. MethodsThis prospective cohort study analyzed the impact of differentlevels of thyroid stimulating hormone ( TSH) onclinical outcomes in patients with coronary heart diseasepost PCI. All the patients were divided into two groupswith normal thyroid function (ET group) and subclinicalhypothyroidism ( SCH group);SCH group was furtherdivided into: SCH group 1 (slightly elevated TSH level:4. 5 - 6. 9 mIU/L) and SCH group 2 (Intermediate elevationof TSH levels > 7. 0 mIU /L). Adverse clinicaloutcome includes: non-fatal myocardial infarction,revascularization,complex events, cardiogenic death afterPCI. The independent correlation between various thyroidhormone levels and adverse clinical outcomes wasassessed by multivariate Cox regression analysis. 展开更多
关键词 PCI IMPACT SUBCLINICAL HYPOTHYROIDISM patients coronary heart disease Cox
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达格列净治疗糖尿病合并冠心病老年患者的效果及对心功能的影响
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作者 王智勇 饶盛环 叶文成 《中国当代医药》 CAS 2024年第8期43-46,共4页
目的探讨达格列净治疗糖尿病合并冠心病老年患者的效果及对心功能的影响。方法选取2021年7月至2022年12月抚州市第一人民医院收治的80例糖尿病合并冠心病老年患者作为研究对象,按照随机数字表法分为观察组(40例)与对照组(40例),观察组... 目的探讨达格列净治疗糖尿病合并冠心病老年患者的效果及对心功能的影响。方法选取2021年7月至2022年12月抚州市第一人民医院收治的80例糖尿病合并冠心病老年患者作为研究对象,按照随机数字表法分为观察组(40例)与对照组(40例),观察组采用达格列净治疗,对照组采用二甲双胍治疗。比较两组的治疗总有效率、氨基末端pro脑钠肽(NT-proBNP)、超敏C反应蛋白(hs-CRP)、心功能水平。结果观察组治疗后总有效率高于对照组,差异有统计学意义(P<0.05);观察组治疗后NT-proBNP水平低于对照组,差异有统计学意义(P<0.05);观察组治疗后hs-CRP水平低于对照组,差异有统计学意义(P<0.05);观察组治疗后左室舒张末期内径(LVEDD)低于对照组,观察组治疗后左室射血分数(LVEF)、舒张早期和舒张晚期二尖瓣口最大血流速度之比(E/A)、6 min步行距离高于对照组,差异有统计学意义(P<0.05)。结论达格列净治疗投入临床糖尿病合并冠心病老年患者治疗中,所得干预的评估结果更好。在实施治疗之后,患者的症状得到较好的改善,且NT-proBNP、hs-CRP指数减少,患者心功能水平得到一定的改善,值得被临床应用推广。 展开更多
关键词 达格列净 糖尿病合并冠心病 老年患者 心功能
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双心照护模式在冠脉介入术后患者生活质量中的相关性分析
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作者 刘媛媛 张亚玲 +1 位作者 王志强 李辉 《新疆医学》 2024年第8期1002-1007,共6页
目的探索双心照护模式对老年冠心病患者冠脉介入术后的不良心理状态与生活质量的影响。方法选取经皮冠状动脉介入术后患者64例,其中男41例,女23例,平均年龄73.45±3.26岁,随机分为观察组和对照组,对照组给予常规护理及心理健康教育... 目的探索双心照护模式对老年冠心病患者冠脉介入术后的不良心理状态与生活质量的影响。方法选取经皮冠状动脉介入术后患者64例,其中男41例,女23例,平均年龄73.45±3.26岁,随机分为观察组和对照组,对照组给予常规护理及心理健康教育指导,观察组在常规护理的基础上给予双心照护,3个月后分别比较两组患者一般临床资料、医院焦虑抑郁量表(HADS)、健康调查简表(SF-36)及满意度差异。结果(1)观察组与对照组的一般临床资料无明显差异(P>0.05)。(2)双心照护干预后,观察组焦虑、抑郁评分、SF-36评分、满意度评分均得到改善,差异均有统计学意义(P<0.05)。(3)相关性分析显示,干预后与出院前观察组HADS中焦虑、抑郁评分差值与患者的情感职能、精神健康评分差值均呈正相关(P<0.05)。结论双心照护模式不仅改善PCI手术后老年患者焦虑、抑郁的不良心理状态,提高患者的生活质量,而且这种心理健康的恢复与生活质量的转变存在正相关性。 展开更多
关键词 冠心病 经皮冠状动脉介入治疗术后 双心照护 老年患者
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地奥心血康软胶囊联合依那普利对冠心病合并心房颤动患者血压测量波动性的影响
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作者 廖然 罗潇 陈玲 《吉林医学》 CAS 2024年第2期404-408,共5页
目的:探讨地奥心血康软胶囊联合依那普利对冠心病合并心房颤动患者血压测量波动性的影响。方法:选取2021年1月~2021年10月就诊于九江市第一人民医院的136例冠心病合并持续性非瓣膜性心房颤动患者,计算分析包括年龄、性别、合并疾病、合... 目的:探讨地奥心血康软胶囊联合依那普利对冠心病合并心房颤动患者血压测量波动性的影响。方法:选取2021年1月~2021年10月就诊于九江市第一人民医院的136例冠心病合并持续性非瓣膜性心房颤动患者,计算分析包括年龄、性别、合并疾病、合并用药等参数在内的各项因素和血压波动的相关性,并就是否联合使用地奥心血康软胶囊在管理血压波动方面的价值进行探索。结果:年龄、性别、合并疾病(高血压、糖尿病、卒中、心力衰竭、高脂血症)、合并用药[血管紧张素转化酶抑制剂(ACEI)、血管紧张素受体拮抗剂(ARB)、β受体阻滞剂、钙离子通道阻滞剂(CCB)、利尿剂、抗凝药、抗血小板药、他汀]与基线水平血压波动之间的相关性差异无统计学意义(P>0.05);在将计算血压波动结点值设置为“6 mmHg”这一前提下,总体研究对象的血压波动达标率为29.4%,联药组在随访过程中的血压波动达标率呈逐渐上升趋势,单药组的血压波动达标率也呈现了波动性,单药组对应时间节点的血压波动达标率较之于联药组均偏低。结论:地奥心血康软胶囊与血压管理具有良好的相关性且能够降低血压的波动性,可以考虑联合依那普利作为降压控压方案。 展开更多
关键词 地奥心血康软胶囊 冠心病合并房颤 血压测量 波动性 新型降压方案
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基于隐结构模型探讨冠心病合并高血压糖尿病患者中医证候特征 被引量:2
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作者 肖欣昂 李洁韵 +3 位作者 夏雨墨 许朝霞 林洁琪 王忆勤 《中国中医药信息杂志》 CAS CSCD 2024年第7期141-147,共7页
目的基于隐结构模型探讨冠心病合并高血压糖尿病患者的中医证候特征。方法采用多中心横断面研究的方法,使用本课题组研制的《冠心病中医四诊采集量表》收集患者中医四诊信息,建立临床数据库。结合频次分析和专家意见筛选四诊信息构建隐... 目的基于隐结构模型探讨冠心病合并高血压糖尿病患者的中医证候特征。方法采用多中心横断面研究的方法,使用本课题组研制的《冠心病中医四诊采集量表》收集患者中医四诊信息,建立临床数据库。结合频次分析和专家意见筛选四诊信息构建隐结构模型。结果共收集冠心病合并高血压糖尿病患者702例,筛选得到高频四诊症状40个,隐结构模型分析得到18个隐变量,模型贝叶斯信息准则评分为-17604.38。对模型中隐变量进行综合聚类,发现冠心病合并高血压糖尿病患者病位证素主要有心、肝、肾等,病性证素主要有气虚、阴虚、气滞、痰浊、血瘀等,归纳其证型主要有痰瘀互结证、脾肾阳虚证、肝郁气滞证、肝肾阴虚证、湿热内蕴证5类,并提示各证型与四诊信息间的互信息及信息覆盖度。结论隐结构模型分析可为冠心病合并高血压糖尿病患者的证候分类提供一定的定性定量依据。 展开更多
关键词 冠心病 合并病 隐结构模型 证候特征
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