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Coronary tortuosity is associated with reversible myocardial perfusion defects in patients without coronary artery disease 被引量:8
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作者 LI Yang LIU Nai-feng +5 位作者 GU Zhong-ze CHEN Yong LU Jun FENG Yi MA Gen-shan SHEN Cheng-xing 《Chinese Medical Journal》 SCIE CAS CSCD 2012年第19期3581-3583,共3页
Coronary artery disease (CAD) is the leading cause of cardiovascular death in the Chinese population.Coronary angiography is the golden standard for the diagnosis of CAD and coronary tortuosity (CT) is a common co... Coronary artery disease (CAD) is the leading cause of cardiovascular death in the Chinese population.Coronary angiography is the golden standard for the diagnosis of CAD and coronary tortuosity (CT) is a common coronary angiographic finding, however, little work has been done on clinical manifestation and significance of CT. It was hypothesized that CT may be associated with angina pectoris and abnormal exercise stress test in patients without CAD, but weather CT can lead to cardiac ischemia has not yet been clarified. The purpose of this study was to determine the impact of CT on myocardial perfusion detects. 展开更多
关键词 coronary tortuosity cardiac ischemia myocardial perfusion defects coronary pressure
原文传递
Relationship between Coronary Artery Tortuosity and Cardiorespiratory Fitness in Patients without Obstructed Coronaries
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作者 Wan-jun LIU Menaka DHUROMSINGH +4 位作者 Xing-wei HE Yang XIE Xiao-lei LIU Hong-jie WANG He-song ZENG 《Current Medical Science》 SCIE CAS 2022年第5期941-948,共8页
Objective This study aimed to analyze the relationship between cardiorespiratory fitness(CRF)and the increasing severity of coronary artery tortuosity(CAT)in patients with non-stenosed coronaries.Methods A total of 39... Objective This study aimed to analyze the relationship between cardiorespiratory fitness(CRF)and the increasing severity of coronary artery tortuosity(CAT)in patients with non-stenosed coronaries.Methods A total of 396 patients who underwent coronary angiography and cardiopulmonary exercise testing(CPET)between August 2020 and July 2021 were included in this single-center retrospective study after excluding patients with significant coronary artery disease(≥50%stenosis).Patients were divided into two groups:no or mild coronary artery tortuosity(N/M-CAT)and moderate to severe coronary artery tortuosity(M/S-CAT)and laboratory electrocardiographic,echocardiographic,and CPET parameters were compared between two groups.Results M/S-CAT was found in 46.9%of the study participants,with 66.7%being women.M/S-CAT was significantly associated with advanced age(P=0.014)and females(P=0.001).Diastolic dysfunction parameters,E velocity(P=0.011),and E/A ratio(P=0.004)also revealed significant differences between the M/S-CAT group and N/M-CAT group.VO2@peak(1.22±0.39 vs.1.07±0.39,P<0.01)and VO2@AT(0.77±0.22 vs.0.71±0.21,P=0.017)were significantly lower in the M/S-CAT group than in the N/M-CAT group.Multivariate logistic regression analysis identified females(OR=0.448;95%CI,0.296–0.676;P=0.000)and E/A ratio(OR=0.307;95%CI,0.139–0.680;P=0.004)to be independent risk factors of M/S-CAT and showed no association of CPET parameters to M/S-CAT.Conclusion The results indicate that increasing severity of CAT is strongly associated with female gender and E/A ratio and is not directly correlated with decreasing CRF.Further research with a larger patient population and a longer follow-up time is required to fully comprehend the impact of CAT on CRF. 展开更多
关键词 coronary angiography coronary artery tortuosity cardiopulmonary exercise testing left ventricular dysfunction
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