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Trends of Noninvasive Radiofrequency and Minimally Invasive Treatment for the Management of Facial Aging
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作者 Sunghee Kim Moonjong Kim 《Journal of Cosmetics, Dermatological Sciences and Applications》 2019年第1期30-40,共11页
Various treatments for the management of facial aging have been performed among which noninvasive radio-frequency (RF;i.e., thermage) treatment and minimally invasive treatments are on the rise. The purpose of this st... Various treatments for the management of facial aging have been performed among which noninvasive radio-frequency (RF;i.e., thermage) treatment and minimally invasive treatments are on the rise. The purpose of this study was to analyze trends of the treatment of facial aging in Korea and to investigate relationships between the use of noninvasive RF and minimally invasive treatments. A retrospective analysis conducted on data from 4021 patients showed that thermage treatment increased by 134.9% over 5 years. As a person ages, the rate of facial treatment with both the botulinum toxin (for the masseter and lines of the glabella, lateral canthus, and forehead) and the PDO thread lift increases. The use of the treatments, nasolabial fold filler and Silhouette Soft Thread, however, was not associated with aging. The patients receiving thermage treatment were less likely to undergo any of the other treatments including PDO thread lift, Silhouette Soft Thread, nasolabial fold filler, or any of the botulinum toxin treatments. Overall, the results showed that patients who had received noninvasive RF tended to receive less minimally invasive treatment. 展开更多
关键词 facial aging NONINVASIVE TREATMENT RADIO-FREQUENCY Thermage MINIMALLY INVASIVE TREATMENT
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Expanded Follicle-Sulcus-Crack Complex Is an Early Warning Sign of Facial Skin Aging: Improvement by Application of Galactomyces Ferment Filtrate-Containing Skin Product
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作者 Kukizo Miyamoto Bandara Dissanayake +3 位作者 Shenal Wanigasekara Keisuke Fujii Xianghong Yan Masutaka Furue 《Journal of Cosmetics, Dermatological Sciences and Applications》 2023年第2期91-106,共16页
Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together... Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together adjacent sulci. This follicle-sulcus-crack complex (FSCC) is exacerbated by dehydration. Purpose: Although dehydration is associated with facial skin aging, FSCC’s implications in facial skin aging remain unresolved. Method: We measured facial skin parameters in 1999 and 2010 in 108 Japanese women, and in 2006 and 2016 in 182 Chinese women. We addressed whether expansion of FSCC is associated with other skin aging parameters. We also examined whether skin moisturizer can reverse the expanded FSCC. Results: In both clinical studies, FSCC severity as well as wrinkles, spots, and roughness significantly deteriorated with age. Notably, FSCC significantly increased as early as in subjects in their 20s, whereas wrinkles, spots, and roughness became conspicuous in those in their 40s or older. Moreover, subjects with more severe FSCC in the initial measurement exhibited significantly worse wrinkles, spots, and roughness in the second measurement a decade later. Dehydration was significantly correlated with expanded FSCC. Furthermore, FSCC expansion was reversed after appropriate moisturization by daily application of Galactomyces ferment filtrate (GFF)-containing skincare product (SK-II Skin Power Cream) for 4 weeks in 37 women. Conclusion: The expanded FSCC is likely to be an early indicator of facial skin aging. Appropriate moisturization may reduce FSCC formation and decelerate facial skin aging. 展开更多
关键词 facial Skin aging Follicle-Sulcus-Crack Complex DEHYDRATION Hyperpigmented Spot WRINKLE Galactomyces Ferment Filtrate
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Six Amino Acids among Natural Moisturizing Factors Responsible for Skin Hydration: Improvement and Anti-Aging of Skin by Galactomyces Ferment Filtrate-PiteraTM Containing Skin Moisturizer
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作者 Kukizo Miyamoto Yoko Munakata +4 位作者 Keisuke Fujii Wang Summer Ley Yang Suda Sudarsana Masutaka Furue 《Journal of Cosmetics, Dermatological Sciences and Applications》 2024年第2期113-127,共15页
Background: Natural moisturizing factors (NMFs) are filaggrin-derived components in the cornified layer that are critical for maintaining healthy skin moisturization and barrier function. However, studies have reporte... Background: Natural moisturizing factors (NMFs) are filaggrin-derived components in the cornified layer that are critical for maintaining healthy skin moisturization and barrier function. However, studies have reported conflicting findings on the relationship between NMF levels and aging, while few studies have investigated this relationship clinically. To fill this research gap, we determined the levels of major NMF components such as free amino acids, pyrrolidone carboxylic acid, and urocanic acids, and individually verified their relationships with skin hydration, barrier function, age, and skin aging. Purpose: The objective of this study was to clinically investigate the relationship between NMF components levels and skin aging in facial skin. The main NMF components were obtained from facial skin and quantified. We then selected NMF components showing strong relationships to skin hydration, and analyzed the relationships of the levels of these selected NMF components with signs of skin aging, namely, texture, pores, wrinkles, and dullness (L-value). We also examined the efficacy of treatment with a skin care formula (SK-II Facial Treatment Essence, called SK-II FTE hereafter) including Galactomyces ferment filtrate (GFF, PiteraTM) on the selected NMF component levels associated with skin hydration and barrier function, and the signs of skin aging of texture, pores, wrinkles, and dullness (L-value). Method: We conducted two clinical trials in this research. In Study 1, we measured 23 NMF components using tape-stripped cornified layer to quantify them via an HPLC method in 196 Asian females aged 20 to 59 (mean S.D., 38.6 9.4). Facial visual aging parameters [texture, pores, wrinkles, and dullness (L-value)], as well as elasticity (R7), skin hydration, and TEWL, were quantified using facial skin imaging and skin physical property measurement devices. Study 2 was performed to evaluate whether the facial application of SK-II FTE affects the NMF levels and skin aging parameters in 63 Asian female volunteers aged 20 to 55 (38.4 9.03). During the course of Study 2, 0.6 mL of SK-II FTE was applied to the face twice daily in the morning and afternoon. Skin measurements were performed at the start of the day (baseline) and at week 8. Results: In Study 1, we examined the stratum corneum levels of 23 NMF components comparing to the skin hydration status in 196 female subjects. The subjects were divided into two groups using the median of each measured NMF component. Skin hydration values were compared between the two groups defined for each NMF component. The results showed that subjects with higher levels of six amino acids, alanine, arginine, asparagine, glutamine, glycine, and histidine, exhibited significantly higher skin hydration than those with lower amino acid levels. No significant differences in skin hydration values were found for the other 17 NMF components. We then analyzed whether the sum of these six amino acid NMF components (called 6-AA-NMFs, hereafter) is affected by aging. The 6-AA-NMF level peaked in the subjects aged 25-29, and then gradually and significantly decreased with age. Interestingly, the 6-AA-NMF level was significantly correlated with the skin hydration value, but not with TEWL. In addition, the 6-AA-NMF level demonstrated significant correlations with the signs of skin aging of texture, pores, wrinkles, and dullness (L-value). Then, in Study 2, we examined whether the daily application of SK-II FTE affects the 6-AA-NMF level and visual aging parameters in 63 females. SK-II FTE demonstrated significant increases of the levels of 6-AA-NMFs and each of its components associated with hydration and barrier function, and improvements of skin texture, pores, wrinkles, and dullness (L-value) during the 8 weeks of treatment of facial skin. Conclusion: These clinical studies with large numbers of subjects across a wide age range revealed that six amino acids as NMF components were highly correlated with facial skin hydration in the stratum corneum. The levels of these six NMF components were also found to decrease at ages after the 30 s and were significantly correlated with major signs of skin aging. Notably, these six NMF components (6-AA-NMFs) were increased by SK-II FTE treatment associated with improvements of skin hydration and signs of skin aging, namely, texture, pores, wrinkles, and dullness (L-value). These studies were limited by the lack of investigation of why some NMF components were not associated with skin hydration. More clinical trials examining various NMF components and their relationship with aging are anticipated. 展开更多
关键词 NMF Amino Acid Visual aging Parameter Hydration aging Texture Pore Wrinkle Dullness Galactomyces Ferment Filtrate PiteraTM SK-II facial Treatment Essence
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Quantification of In Vivo Epidermal Keratinocyte Architecture Associated with the Signs of Skin Aging and the Skin Benefit Evaluation by Application of Galactomyces Ferment Filtrate (Pitera)-Containing Skin Care Product
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作者 Kukizo Miyamoto Yoko Munakata +4 位作者 Keisuke Fujii Chenlu Lei Ley Yang Suda Sudarsana Masutaka Furue 《Journal of Cosmetics, Dermatological Sciences and Applications》 2024年第1期12-28,共17页
Background: Aged skin exhibits visual alterations such as wrinkles, rough texture, pore dilation, and dull skin tone, as well as physiological aging, namely, decreased hydration and increased transepidermal water loss... Background: Aged skin exhibits visual alterations such as wrinkles, rough texture, pore dilation, and dull skin tone, as well as physiological aging, namely, decreased hydration and increased transepidermal water loss (TEWL). Recent advances in coherence tomography have also revealed that skin aging affects in vivo epidermal keratinocyte architecture. However, the interconnectivity between spatial architectural aging and visual/physiological aging parameters remains largely unknown. Purpose: To elucidate whether the tomographic keratinocyte architectural aging is correlated with visual and physiological skin aging parameters and to quantitatively evaluate the improvements of the architectural, visual, and physiological aging parameters by the daily treatment of the skin care formula containing Galactomyces Ferment Filtrate (GFF, 8X Pitera<sup>TM</sup>). Method: We measured the in vivo keratinocyte cellular architecture with two-photon stereoscopic tomography obtaining by-layer epidermal section images in 78 Asian females of various ages. Visual aging parameters were analyzed using a portable image capture system. Hydration and TEWL were also assessed. The anti-aging effects of GFF-containing skin moisturizer (SK-II LXP Cream<sup>TM</sup>) were also examined in two studies after twice-daily application for 2 (N = 35) and 4 (N = 32) weeks. Results: As for the keratinocyte cellular architecture, skin aging was significantly associated with decreased cell density and increased cell uniformity. These architectural aging parameters were significantly correlated with visual and physiological aging parameters, namely, rough texture, wrinkles, pore dilation, dull skin tone, dehydration, and increased TEWL. The strong interconnectivity allowed us to develop formulae to estimate the keratinocyte architecture from visual aging parameters. Moreover, twice-daily application of SK-II significantly improved the keratinocyte architecture associated with multiple skin aging visual and physiological parameters. Conclusion: Skin aging is a process involving mutual interconnections among epidermal keratinocyte cellular architecture, visual, and physiological parameters. The GFF-containing moisturizer SK-II effectively improves spatial architecture of keratinocytes in epidermis and these evaluated skin aging parameters in a new trajectory over the course of treatment. . 展开更多
关键词 facial Skin aging In Vivo Keratinocyte Cellular Architecture Visual aging Pa-rameter Dehydration INTERCONNECTIVITY New Trajectory Galactomyces Fer-ment Filtrate PiteraTM SK-II LXP CreamTM
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基于标记适应的人脸年龄识别优化算法
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作者 张会影 圣文顺 《计算机工程》 北大核心 2025年第1期174-181,共8页
缺乏完整和足够的人脸年龄标记数据集是当前人脸年龄识别问题中最突出的挑战之一。由于相近年龄的面部具有相似性,因此在年龄识别中可以学习并利用相邻年龄的面部信息,将每张人脸图像看作相关年龄的标记分布(LD),从而有效缓解了训练和... 缺乏完整和足够的人脸年龄标记数据集是当前人脸年龄识别问题中最突出的挑战之一。由于相近年龄的面部具有相似性,因此在年龄识别中可以学习并利用相邻年龄的面部信息,将每张人脸图像看作相关年龄的标记分布(LD),从而有效缓解了训练和测试数据集不足的问题。但是在不同年龄阶段,人的面部衰老变化速度显著不同,如儿童和老年时期面部变化较快,而中年时期面部变化较平缓,当前常用的LD方法存在模式单一的缺点,难以适应不同年龄阶段人脸特征的变化规律。为提高人脸年龄识别算法的通用性,提出一种深度学习框架下基于标记适应的人脸年龄识别优化算法IFAR-LA。引入标记适应机制,能够更好地学习特征表示,挖掘人脸图像数据中丰富的语义信息,从而有效提取不同年龄阶段面部变化的特征,大幅提升表示学习能力和泛化能力。改进后的标记适应算法能够适应不同年龄阶段人脸变化规律,使每幅人脸图像在学习其真实年龄和相关年龄的时候都能发挥作用,缓解训练数据不足的问题,同时,提升了算法普适性,能够适应不同年龄阶段人的面部衰老变化速度。在公开的人脸数据集MORPH和FG-NET上的实验结果表明,IFAR-LA算法相比改进前的人脸年龄识别算法平均绝对误差分别降低了6.5%和11.5%。 展开更多
关键词 标记分布学习 深度学习 卷积神经网络 人脸年龄识别 平均绝对误差
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Facial Beautification Method Based on Age Evolution 被引量:1
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作者 CHEN Yan DING Shou-hong +1 位作者 HU Gan-le MA Li-zhuang 《Computer Aided Drafting,Design and Manufacturing》 2013年第4期7-13,共7页
This paper proposes a new facial beautification method using facial rejuvenation based on the age evolution. Traditional facial beautification methods only focus on the color of skin and deformation and do the transfo... This paper proposes a new facial beautification method using facial rejuvenation based on the age evolution. Traditional facial beautification methods only focus on the color of skin and deformation and do the transformation based on an experimental standard of beauty. Our method achieves the beauty effect by making facial image looks younger, which is different from traditional methods and is more reasonable than them. Firstly, we decompose the image into different layers and get a detail layer. Secondly, we get an age-related parameter: the standard deviation of the Gaussian distribution that the detail layer follows, and the support vector machine (SVM) regression is used to fit a function about the age and the standard deviation. Thirdly, we use this function to estimate the age of input image and generate a new detail layer with a new standard deviation which is calculated by decreasing the age. Lastly, we combine the original layers and the new detail layer to get a new face image. Experimental results show that this algo- rithm can make facial image become more beautiful by facial rejuvenation. The proposed method opens up a new way about facial beautification, and there are great potentials for applications. 展开更多
关键词 facial beautification method age evolution support vector machine
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3D Modelling, Simulation and Prediction of Facial Wrinkles
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作者 Sokyna Alqatawneh Ali Mehdi Thamer Al Rawashdeh 《通讯和计算机(中英文版)》 2014年第4期365-370,共6页
关键词 面部皱纹 3D建模 预测 NURBS曲线 仿真 三维系统 警察部门 研究人员
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老年髋部骨折术后1年病死率的危险因素分析及年龄矫正查尔森合并指数对其的预测价值 被引量:1
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作者 陈晓鹏 何久盛 +5 位作者 陈楚鹰 张浩 李林 赵雪东 许渴 廖文利 《骨科临床与研究杂志》 2024年第3期176-182,共7页
目的分析影响老年髋部骨折患者手术后1年病死率的危险因素及年龄矫正查尔森合并指数对其的预测价值。方法回顾性分析2018年1月至2022年11月在北京市顺义区医院创伤骨科行髋部骨折手术治疗的老年患者的病历资料,符合纳入标准共652例,收... 目的分析影响老年髋部骨折患者手术后1年病死率的危险因素及年龄矫正查尔森合并指数对其的预测价值。方法回顾性分析2018年1月至2022年11月在北京市顺义区医院创伤骨科行髋部骨折手术治疗的老年患者的病历资料,符合纳入标准共652例,收集年龄、性别、骨折侧别、骨折类型、美国麻醉医师协会(ASA)分级、住院天数、麻醉方式、术后白蛋白、术后白细胞、术后血红蛋白、年龄矫正查尔森合并指数(ACCI)和是否发生肺炎等信息,分析与患者1年病死率相关的危险因素。结果652例患者术后1年的病死率为21.5%(140/652)。单因素Cox回归分析显示年龄、住院时间、ACCI及术后是否发生肺炎与术后1年病死率有统计学意义。多因素Cox回归分析显示年龄(HR=1.087,95%CI:1.060~1.114,P=0),ACCI(HR=1.645,95%CI:1.548~1.747,P=0),术后发生肺炎(HR=2.353,95%CI:1.624~3.408,P=0)是老年髋部骨折患者1年内死亡的危险因素。ACCI预测老年髋部骨折患者术后1年病死率的AUC为0.912,最佳阈值为5.5时的特异度为0.834,敏感度为0.871。结论年龄、ACCI、术后发生肺炎时老年髋部骨折术后1年死亡的独立危险因素,ACCI对预测老年髋部骨折术后1年病死率有一定价值,可为临床病情评估提供方法。 展开更多
关键词 老年人 髋骨折 术后1年死亡率 年龄矫正查尔森合并指数
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聚焦超声技术在面部抗衰老美容中的应用效果观察
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作者 乔冠群 陈威 +1 位作者 邓乐曲 蔡薇 《南通大学学报(医学版)》 2024年第4期346-348,共3页
目的:探讨聚焦超声技术在面部抗衰老美容中的应用效果。方法:以2023年1—9月在南京医科大学第二附属医院就诊的30例求美者为研究对象。所有求美者均接受聚焦超声技术进行面部美容,应用面部松弛度(facial laxity reflectance,FLR)量表、... 目的:探讨聚焦超声技术在面部抗衰老美容中的应用效果。方法:以2023年1—9月在南京医科大学第二附属医院就诊的30例求美者为研究对象。所有求美者均接受聚焦超声技术进行面部美容,应用面部松弛度(facial laxity reflectance,FLR)量表、全局美容效果(global aesthetic improvement scale,GAIS)量表对美容效果进行评估,应用FACE-Q量表对求美者治疗前、治疗后3个月的外观满意度、心理状态和社会功能进行评价,并观察不良反应。结果:求美者术前的FLR量表评分较高,治疗后即刻评分明显下降,且治疗后1、3个月的评分仍显著低于术前(P<0.01),而治疗后即刻、1个月及3个月的评分差异无统计学意义(P>0.05)。治疗后GAIS量表评估结果显示,1级15例(50.00%),2级10例(33.33%),3级5例(16.67%);求美者术前的FACE-Q量表中外观满意度、心理状态及社会功能评分均较低,治疗后3个月时均较治疗前明显提高(P<0.01);治疗后出现红斑1例,肿胀疼痛1例,发生不良反应共2例(6.67%)。结论:聚焦超声技术在面部抗衰老美容中的应用效果良好,不良反应较少,能显著提升患者美观度,减轻求美者自卑心理,提高自信心和社交能力,生活质量显著改善,值得临床推广应用。 展开更多
关键词 聚焦超声技术 面部 抗衰老 满意度
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面向视频侦查应用的退化人像GFP深度复原技术
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作者 倪新龙 孙鹏 +3 位作者 郎宇博 赵理夫 田天泽 周纯冰 《刑事技术》 2024年第2期111-119,共9页
在视频侦查工作中时常遇到视频人像质量过低难以辨识的情况,而GFP等人像深度复原方法只适用于单张人像的复原。为此,本文提出一种基于GFP的监控视频人像复原技术,将GFP方法扩展至视频侦查应用,便于及时锁定犯罪嫌疑人,提高破案效率。首... 在视频侦查工作中时常遇到视频人像质量过低难以辨识的情况,而GFP等人像深度复原方法只适用于单张人像的复原。为此,本文提出一种基于GFP的监控视频人像复原技术,将GFP方法扩展至视频侦查应用,便于及时锁定犯罪嫌疑人,提高破案效率。首先对监控视频进行视频分帧、人像裁剪对齐、倾斜透视校正等预处理操作,然后使用GFP方法对预处理后得到的人像进行深度复原,最后经过逆处理将复原人像整合成高质量人像视频。在大量经过预处理后的模拟退化人像和无参考退化人像测试集上进行对比实验,结果表明,GFP方法在主观视觉效果和FID、PSFR、SSIM、NIQE等客观量化指标上均优于其他人像深度复原方法,相较于其他人像深度复原方法,能够更有效地复原复杂应用场景下的低质量退化人像,更适用于视频侦查应用;通过使用YTF视频人像数据集进行对比测试实验,结果显示,本文所提出的添加预处理与逆处理过程的基于GFP的监控视频人像复原技术,对于低质量视频人像有更加优秀的复原效果。 展开更多
关键词 视频侦查 监控视频 人像复原 视频分帧 倾斜透视校正 GFP
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SFSR-Age:一种基于人脸强语义的年龄识别算法 被引量:1
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作者 孙旭菲 缪新颖 +2 位作者 毕甜甜 王水涛 喻芳宇 《吉林大学学报(理学版)》 CAS 北大核心 2024年第2期347-356,共10页
针对因光照、拍摄角度及图片质量等因素导致的经典深度学习算法难以有效提取人脸特征、人物身份识别准确率难以达到理想精度的问题,提出一种基于人脸强语义的年龄识别算法.首先,通过注意力矩阵增强人脸区域的特征权重,达到提取特征区域... 针对因光照、拍摄角度及图片质量等因素导致的经典深度学习算法难以有效提取人脸特征、人物身份识别准确率难以达到理想精度的问题,提出一种基于人脸强语义的年龄识别算法.首先,通过注意力矩阵增强人脸区域的特征权重,达到提取特征区域的目的;其次,使用级联双向长短期记忆(Bi-LSTM)网络学习时序帧之间的特征依赖关系,弥补部分特征缺失对识别精度的影响.在人脸数据集IMDB-WIKI和数据集Adience上进行测试,该算法的年龄识别准确率分别达到78.34%和77.89%.实验结果表明,相比于其他基于深度学习算法的方法,该算法在基于图片数据集的人物年龄识别任务上具有更高的准确率. 展开更多
关键词 年龄识别 人脸识别 深度学习算法 注意力矩阵 级联Bi-LSTM
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龄期、食料和密度对小地老虎幼虫自残的影响
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作者 韦东顺 官涵杰 +3 位作者 邹晓 杨茂发 杨相 于晓飞 《山东农业科学》 北大核心 2024年第5期126-131,共6页
小地老虎是农林作物苗期的重要地下害虫,自残行为影响其种群消长,对理清其种群动态规律和预测防治具有重要意义。本研究通过室内建立玉米、小白菜、烟草和人工饲料种群小地老虎,测定龄期、食料和密度对幼虫自残的影响,旨在明确小地老虎... 小地老虎是农林作物苗期的重要地下害虫,自残行为影响其种群消长,对理清其种群动态规律和预测防治具有重要意义。本研究通过室内建立玉米、小白菜、烟草和人工饲料种群小地老虎,测定龄期、食料和密度对幼虫自残的影响,旨在明确小地老虎的自残特性。结果表明,龄期、食料和密度均对小地老虎幼虫校正自残率有显著影响。其中,4个种群同龄期间的校正自残率最高均为5龄,最低均为2龄;不同种群间的自残程度依次为人工饲料种群>小白菜种群>玉米种群>烟草种群;30头/瓶的饲养密度校正自残率最高。不同龄期混合后各种群均显示2龄幼虫被高龄幼虫残杀概率最高,5龄幼虫最低。不同种群的5龄幼虫混合后玉米种群的被残杀率最高,人工饲料种群的较低。龄期、食料和密度对幼虫校正自残率变异均具有显著影响,其中龄期影响最大(26.80%),食料影响最小(4.40%);龄期对幼虫被残杀率变异具有显著影响,解释11%的变异量。 展开更多
关键词 小地老虎 自残 食料 密度 幼虫龄期 校正自残率
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基于自适应尺度混合海森滤波器的面部皱纹检测及评分
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作者 冯月宝平 何冰冰 +3 位作者 郭振宇 张梅 马骁 张榆锋 《应用科技》 CAS 2024年第2期24-30,共7页
为解决全面部皱纹缺乏量化评价方法的问题,提出了一种基于自适应尺度混合海森滤波器(adaptive scale hybrid Hessian filter,ASHHF)的面部皱纹检测方法及评分机制。根据受试者年龄自适应调整海森滤波器的尺寸(σ)范围及步长参数并对其... 为解决全面部皱纹缺乏量化评价方法的问题,提出了一种基于自适应尺度混合海森滤波器(adaptive scale hybrid Hessian filter,ASHHF)的面部皱纹检测方法及评分机制。根据受试者年龄自适应调整海森滤波器的尺寸(σ)范围及步长参数并对其面部高分辨率图像进行滤波,基于81个面部特征点在滤波结果中去除五官、背景,仅保留面部皱纹,使用不同颜色将不同深度的皱纹检测结果标注在原始图像中,最后计算得分量化皮肤衰老程度。以专业医生标注皱纹为参考,50名受试者(年龄为22~65岁)的检测结果表明,相比于传统的固定尺度混合海森滤波器(fixed scale hybrid Hessian filter,FSHHF),ASHHF方法的检测准确率平均提升68.57%,运行时间平均缩短26.26%,评分机制结果与检测准确率的变化趋势一致。综上,本文检测方法能够准确、快速检测面部皱纹分布、深度及宽度,所提评分机制能够科学反映受试者皮肤衰老程度,有望为化妆品、医疗美容等抗衰方法提供功效量化评价手段。 展开更多
关键词 皮肤衰老 面部皮肤 皱纹检测 皱纹识别 皱纹评分机制 混合海森滤波器 自适应尺度 年龄
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面部埋线提升术联合自体脂肪颗粒移植行面部轮廓年轻化
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作者 张继 陈言汤 《中国医疗美容》 2024年第8期46-49,共4页
目的 分析面部埋线提升术联合自体脂肪颗粒移植术对中老年面部轮廓的改善效果。方法 将2023年1月至2024年1月在郑州蒂莱美医疗美容医院寻求面部年轻化的34例中老年患者纳入研究。给予患者面部埋线提升术联合自体脂肪颗粒移植术。比较患... 目的 分析面部埋线提升术联合自体脂肪颗粒移植术对中老年面部轮廓的改善效果。方法 将2023年1月至2024年1月在郑州蒂莱美医疗美容医院寻求面部年轻化的34例中老年患者纳入研究。给予患者面部埋线提升术联合自体脂肪颗粒移植术。比较患者治疗前、治疗3个月后面部皱纹量表(front wrinkle scale,FWS)评分、皱纹严重程度评价量表(wrinkle severity rating scale,WSRS)评分;分析患者不良反应发生率。结果 治疗3个月后,患者FWS、WSRS评分与治疗前比较均有明显下降(P<0.05);患者治疗并发症主要为水肿(41.18%)、疼痛(17.65%)、淤青(32.35%)、左右不对称(5.88%)和面部凹凸不平(5.88%),经对症处理后,并发症迅速缓解,未影响患者远期预后。结论 面部埋线提升术联合自体脂肪颗粒移植术可面部轮廓提升、饱满,具有显著的年轻化效果。 展开更多
关键词 面部轮廓 中老年 面部埋线提升术 自体脂肪颗粒移植术 面部年轻化
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Correction to:SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer
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《Protein & Cell》 SCIE CSCD 2024年第1期76-77,共2页
This is a correction to:Shijia Bi and others,SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer,Protein&Cell,Volume 11,Issue 7,July 2020,Pages 483-504,https://doi.org/10.1007/s13238-020-00728-... This is a correction to:Shijia Bi and others,SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer,Protein&Cell,Volume 11,Issue 7,July 2020,Pages 483-504,https://doi.org/10.1007/s13238-020-00728-4 The authors wish to introduce the following corrections to their article. 展开更多
关键词 correctION aging STABILIZER
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面部深层脂肪室研究进展及临床应用
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作者 杨焜丞 牟浩 +1 位作者 黎丹 张恒术 《中国医疗美容》 2024年第1期112-116,共5页
面部脂肪被肌肉、韧带、筋膜等组织分隔为一个个的独立的脂肪室,且被浅表肌肉腱膜系统(SMAS)分为深浅两层。面部深层脂肪室大部分位于SMAS及骨膜之间,起着缓冲、润滑、支撑等作用。深层脂肪室随年龄出现选择性的增大或萎缩能导致面部外... 面部脂肪被肌肉、韧带、筋膜等组织分隔为一个个的独立的脂肪室,且被浅表肌肉腱膜系统(SMAS)分为深浅两层。面部深层脂肪室大部分位于SMAS及骨膜之间,起着缓冲、润滑、支撑等作用。深层脂肪室随年龄出现选择性的增大或萎缩能导致面部外观出现皱褶、凹陷等老化表现。在临床针对面部年轻化的治疗中,可以通过对面部深层脂肪室进行提升或填充等处理以达到恢复年轻外观、重现青春活力等效果。本文就面部深层脂肪室的解剖、老化改变及相关填充技术进行综述。 展开更多
关键词 深面部 脂肪室 衰老 面部年轻化
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复方血栓通辅助贝伐单抗治疗对湿性老年黄斑变性主要和次要结局的作用
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作者 任刚 甘国菊 《临床误诊误治》 CAS 2024年第13期95-100,共6页
目的探讨复方血栓通辅助贝伐单抗治疗湿性老年黄斑变性(wAMD)的临床效果。方法选取2021年4月至2023年5月收治的62例wAMD患者,随机数字表法分为2组,各31例。单抗组予以贝伐单抗治疗,联合组予以复方血栓通联合贝伐单抗治疗,2组均治疗3个... 目的探讨复方血栓通辅助贝伐单抗治疗湿性老年黄斑变性(wAMD)的临床效果。方法选取2021年4月至2023年5月收治的62例wAMD患者,随机数字表法分为2组,各31例。单抗组予以贝伐单抗治疗,联合组予以复方血栓通联合贝伐单抗治疗,2组均治疗3个月。比较2组临床疗效、最佳矫正视力(BCVA)最小分辨角对数(LogMAR)、黄斑中心凹视网膜厚度(CRT)、眼血流动力学[收缩期峰值流速(PSV)、舒张末期流速(EDV)、阻力指数(RI)]、血清因子[血管内皮生长因子(VEGF)、白细胞介素-1(IL-1)、IL-6、IL-17、血管内皮细胞生长抑制因子(VEGI)、肿瘤坏死因子-α(TNF-α)]及不良反应。结果联合组总有效率为93.55%(29/31)高于单抗组70.97%(22/31)(P<0.05)。联合组治疗1、3个月后BCVA(LogMAR)优于单抗组,CRT低于单抗组(P<0.05);联合组治疗1、3个月后RI、IL-6、TNF-α、IL-1、IL-17、VEGF低于单抗组,PSV、EDV、VEGI高于单抗组(P<0.05)。联合组贝伐单抗的注射次数少于单抗组(P<0.01)。2组不良反应发生率比较无显著差异(P>0.05)。结论复方血栓通辅助贝伐单抗治疗wAMD可有效调控血管生成因子水平,抑制促炎因子,改善眼血流动力学,减少贝伐单抗注射次数,从而改善局部病变,且治疗安全性高。 展开更多
关键词 湿性黄斑变性 老年人 复方血栓通 贝伐单抗 最佳矫正视力 血流动力学 血管内皮生长因子 白细胞介素-1
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比较YEARS评分与简化Wells联合年龄校正D-二聚体评分用于疑似肺栓塞患者的诊断价值
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作者 谭笑 郭燕妮 《临床肺科杂志》 2024年第12期1838-1843,共6页
目的通过前瞻性研究比较YEARS评分与简化Wells联合年龄校正D-二聚体评分(sWells-Age)用于疑似肺栓塞患者的诊断价值。方法纳入2021年3月3日到2022年4月30日于宜宾市第二人民医院就诊且符合纳排标准的可疑肺栓塞病人522名,采用前瞻性观... 目的通过前瞻性研究比较YEARS评分与简化Wells联合年龄校正D-二聚体评分(sWells-Age)用于疑似肺栓塞患者的诊断价值。方法纳入2021年3月3日到2022年4月30日于宜宾市第二人民医院就诊且符合纳排标准的可疑肺栓塞病人522名,采用前瞻性观察研究,由临床医师对照YEARS评分收集患者基线信息,计算患者YEARS评分及sWells-Age评分判断其目前肺栓塞临床可能性。所有排除肺栓塞且未进行抗凝治疗的患者进行3个月随访。以CTPA检查结果作为诊断金标准,分别计算YEARS评分及sWells-Age评分敏感度、特异度、κ值等指标,绘制两者ROC曲线并计算AUC值。结果sWells-Age评分及YEARS评分灵敏度分别为85.71%、93.41%(P<0.001),特异度分别为69.23%、56.92%(P<0.001),AUC值分别为0.775(95%CI 0.688~0.816)、0.752(95%CI 0.711~0.838),与CTPA的κ值分别为0.526、0.465,均>0.410,结果一致性均属于中等,两者灵敏度比较(χ^(2)=5.143,P<0.025),差异具有统计学意义,两者特异度比较(χ^(2)=12.500,P<0.001),差异具有显著统计学意义。结论sWells-Age评分优于YEARS评分,但YEARS评分项目少,灵敏度及安全性高,可应用于早期肺栓塞患者的筛查。 展开更多
关键词 肺栓塞 YEARS评分 简化Wells评分 年龄校正 D-二聚体
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透明质酸无针水光注射配合黄金微针射频治疗皮肤老化的效果观察 被引量:1
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作者 杨林洪 董美丽 +1 位作者 王东霞 翟婉芳 《中国医疗美容》 2024年第4期53-56,共4页
目的探析透明质酸无针水光注射配合黄金微针射频治疗皮肤老化的效果。方法回顾性分析2021年7月~2023年12月来桂林市人民医院皮肤科要求改善面部皮肤老化的就医者60例,按治疗方式的差异将其分为A组与B组,各30例。A组患者采用单独黄金微... 目的探析透明质酸无针水光注射配合黄金微针射频治疗皮肤老化的效果。方法回顾性分析2021年7月~2023年12月来桂林市人民医院皮肤科要求改善面部皮肤老化的就医者60例,按治疗方式的差异将其分为A组与B组,各30例。A组患者采用单独黄金微针射频治疗,B组患者采用黄金微针射频联合透明质酸无针水光注射治疗(于射频治疗后第1周、第2周、第3周、第4周给予透明质酸无针水光注射)。两组患者均间隔3个月进行一次黄金微针射频治疗,2次为1个疗程。比较两组临床疗效、面部年轻化程度[面部皱纹量表(FWS)、皱纹严重程度评价量表(WSRS)]、面部VISIA评分、不良反应。结果治疗24周结束时,B组有效率高于A组(P<0.05);治疗24周,两组FWS、WSRS评分均高于治疗前,且B组更高(P<0.05);两组治疗前VISIA评分比较,差异无统计学意义(P>0.05);治疗后4周、治疗后12周、治疗后24周两组VISIA评分高于治疗前,且B组治疗后4周、治疗后12周、治疗后24周VISIA评分均高于A组(P<0.05);两组患者不良反应比较,无明显差异(P>0.05)。结论透明质酸无针水光注射配合黄金微针射频治疗皮肤老化的疗效确切,可显著实现面部年轻化。 展开更多
关键词 透明质酸注射 黄金微针 面部皮肤老化
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人际互动中沉没成本效应的年龄差异:面孔与行为可信度的作用
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作者 李国根 牟忠琛 +2 位作者 程雨 贵文君 张林 《心理技术与应用》 2024年第9期513-526,共14页
探讨人际互动中互动对象可信度对沉没成本效应的影响,及在不同年龄群体中的变化趋势。共设计两个实验,结果显示:(1)面孔信任度对沉没成本效应的影响存在年龄差异,即与年轻人相比,老年人与高信任面孔互动时表现出更大的沉没成本效应,(2)... 探讨人际互动中互动对象可信度对沉没成本效应的影响,及在不同年龄群体中的变化趋势。共设计两个实验,结果显示:(1)面孔信任度对沉没成本效应的影响存在年龄差异,即与年轻人相比,老年人与高信任面孔互动时表现出更大的沉没成本效应,(2)不同可信度信息对沉没成本效应的影响存在差异。老年人的沉没成本效应主要受面孔可信度的持续影响,而行为可信度对其影响较小。年轻人的沉没成本效应在初期主要受面孔可信度影响,但随着互动次数的增加,行为可信度逐渐起主导作用。研究揭示在人际互动中不同年龄群体对可信度信息的处理存有差异,提示在设计信息传递方式和决策支持系统中应当针对不同年龄段的个体采取差异化策略。 展开更多
关键词 沉没成本效应 人际互动 面孔可信度 行为可信度 老化
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