目的:探究宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症的效果。方法:前瞻性选取2021年10月—2022年10月新泰市人民医院收治的104例子宫内膜息肉不孕症患者,按手术方法不同分为研究组52例和对照组52例。对照组采取宫腔镜下刮...目的:探究宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症的效果。方法:前瞻性选取2021年10月—2022年10月新泰市人民医院收治的104例子宫内膜息肉不孕症患者,按手术方法不同分为研究组52例和对照组52例。对照组采取宫腔镜下刮宫术治疗,研究组采取宫腔镜下电切术治疗,且两组均联合屈螺酮炔雌醇治疗,治疗3个周期。比较两组临床疗效、月经失血图(pictorial blood loss assessment chart,PBAC)评分、子宫内膜厚度、并发症、复发率及妊娠率。结果:研究组疗效、总有效率均高于对照组,差异有统计学意义(P<0.05)。术后3个周期,两组PBAC评分低于术前,且研究组PBAC评分低于对照组,差异有统计学意义(P<0.05)。术后3个周期,两组子宫内膜厚度低于术前,且研究组子宫内膜厚度低于对照组,差异有统计学意义(P<0.05)。两组宫颈狭窄、子宫粘连、宫内感染等并发症总发生率比较,差异无统计学意义(P>0.05)。研究组术后6个月、12个月复发率低于对照组,妊娠率均高于对照组,差异有统计学意义(P<0.05)。结论:宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症临床效果更好,可有效改善患者PBAC评分与子宫内膜厚度,降低复发率,提高妊娠率,且安全性较好。展开更多
This study aimed to assess the reliability of experienced Chinese orthodontists in evaluating treatment outcome and to determine the correlations between three diagnostic information sources. Sixty-nine experienced Ch...This study aimed to assess the reliability of experienced Chinese orthodontists in evaluating treatment outcome and to determine the correlations between three diagnostic information sources. Sixty-nine experienced Chinese orthodontic specialists each evaluated the outcome of orthodontic treatment of 108 Chinese patients. Three different information sources： study casts （SC）, lateral cephalometric X-ray images （LX） and facial photographs （PH） were generated at the end of treatment for 108 patients selected randomly from six orthodontic treatment centers throughout China. Six different assessments of treatment outcome were made by each orthodontist using data from the three information sources separately and in combination. Each assessment included both ranking and grading for each patient. The rankings of each of the 69 judges for the 108 patients were correlated with the rankings of each of the other judges yielding 13 873 Spearman rs values, ranging from -0.08 to ＋0.85. Of these, 90% were greater than 0.4, showing moderate-to-high consistency among the 69 orthodontists. In the combined evaluations, study casts were the most significant predictive component （R2=0.86, P〈0.000 1）, while the inclusion of lateral cephalometric films and facial photographs also contributed to a more comprehensive assessment （R2=0.96, P〈0.000 1）. Grading scores for SC＋LX and SC＋PH were highly significantly correlated with those for SC＋LX＋PH （r（SC＋LX）vs.（SC＋LX＋PH）=0.96, r（SC＋PH）vs.（SC＋LX＋PH）=0.97）, showing that either SC＋LX or SC＋PH is an excellent substitute for all three combined assessment,展开更多
OBJECTIVE: To observe the clinical effect of Gushenyutai plaster administered at the Guanyuan(CV4) acupoint on male infertility associated with semen non-liquefaction.METHODS: Sixty-two male patients with infertility ...OBJECTIVE: To observe the clinical effect of Gushenyutai plaster administered at the Guanyuan(CV4) acupoint on male infertility associated with semen non-liquefaction.METHODS: Sixty-two male patients with infertility caused by semen non-liquefaction were random-ized into a treatment and control group. The control group received comprehensive therapy, which included oral administration of clarithromycin sustained release tablets, hip bath with Zhongyaoxiaoyan granules, prostate massage, and transurethral microwave treatment. The treatment group was administered Gushenyutai plaster in addition to the comprehensive therapy. Both groups were treated for 8 weeks. After treatment, the clinical effect and pregnancy rate were assessed and compared between the two groups.RESULTS: The effective rate of the treatment group was significantly higher than that of the control group(96.77% vs 70.97%, P<0.05) and the pregnancy rates of the treatment group and control groups were 38.71% and 16.13%, respectively(P<0.05).CONCLUSION: The effect of Gushenyutai plaster plus comprehensive therapy was better than that of the comprehensive therapy alone on male infertility induced by semen non-liquefaction.展开更多
文摘目的:探究宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症的效果。方法:前瞻性选取2021年10月—2022年10月新泰市人民医院收治的104例子宫内膜息肉不孕症患者,按手术方法不同分为研究组52例和对照组52例。对照组采取宫腔镜下刮宫术治疗,研究组采取宫腔镜下电切术治疗,且两组均联合屈螺酮炔雌醇治疗,治疗3个周期。比较两组临床疗效、月经失血图(pictorial blood loss assessment chart,PBAC)评分、子宫内膜厚度、并发症、复发率及妊娠率。结果:研究组疗效、总有效率均高于对照组,差异有统计学意义(P<0.05)。术后3个周期,两组PBAC评分低于术前,且研究组PBAC评分低于对照组,差异有统计学意义(P<0.05)。术后3个周期,两组子宫内膜厚度低于术前,且研究组子宫内膜厚度低于对照组,差异有统计学意义(P<0.05)。两组宫颈狭窄、子宫粘连、宫内感染等并发症总发生率比较,差异无统计学意义(P>0.05)。研究组术后6个月、12个月复发率低于对照组,妊娠率均高于对照组,差异有统计学意义(P<0.05)。结论:宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症临床效果更好,可有效改善患者PBAC评分与子宫内膜厚度,降低复发率,提高妊娠率,且安全性较好。
基金supported by the Specific Research Project of Health Pro Bono Sector, Ministry of Health, China (200802056)
文摘This study aimed to assess the reliability of experienced Chinese orthodontists in evaluating treatment outcome and to determine the correlations between three diagnostic information sources. Sixty-nine experienced Chinese orthodontic specialists each evaluated the outcome of orthodontic treatment of 108 Chinese patients. Three different information sources： study casts （SC）, lateral cephalometric X-ray images （LX） and facial photographs （PH） were generated at the end of treatment for 108 patients selected randomly from six orthodontic treatment centers throughout China. Six different assessments of treatment outcome were made by each orthodontist using data from the three information sources separately and in combination. Each assessment included both ranking and grading for each patient. The rankings of each of the 69 judges for the 108 patients were correlated with the rankings of each of the other judges yielding 13 873 Spearman rs values, ranging from -0.08 to ＋0.85. Of these, 90% were greater than 0.4, showing moderate-to-high consistency among the 69 orthodontists. In the combined evaluations, study casts were the most significant predictive component （R2=0.86, P〈0.000 1）, while the inclusion of lateral cephalometric films and facial photographs also contributed to a more comprehensive assessment （R2=0.96, P〈0.000 1）. Grading scores for SC＋LX and SC＋PH were highly significantly correlated with those for SC＋LX＋PH （r（SC＋LX）vs.（SC＋LX＋PH）=0.96, r（SC＋PH）vs.（SC＋LX＋PH）=0.97）, showing that either SC＋LX or SC＋PH is an excellent substitute for all three combined assessment,
基金the Science and Technology Planning for social development Project of Guangdong Province[Guangdong S&T Planning(2011)No.71]the Construction of Chinese Medicine Strong Province Project supported by Administration of Traditional Chinese Medicine of Guangdong Province[Guangdong TCM(2012)No.23]The Social Development Project of Shantou[Shantou Finance(2010)No.480]
文摘OBJECTIVE: To observe the clinical effect of Gushenyutai plaster administered at the Guanyuan(CV4) acupoint on male infertility associated with semen non-liquefaction.METHODS: Sixty-two male patients with infertility caused by semen non-liquefaction were random-ized into a treatment and control group. The control group received comprehensive therapy, which included oral administration of clarithromycin sustained release tablets, hip bath with Zhongyaoxiaoyan granules, prostate massage, and transurethral microwave treatment. The treatment group was administered Gushenyutai plaster in addition to the comprehensive therapy. Both groups were treated for 8 weeks. After treatment, the clinical effect and pregnancy rate were assessed and compared between the two groups.RESULTS: The effective rate of the treatment group was significantly higher than that of the control group(96.77% vs 70.97%, P<0.05) and the pregnancy rates of the treatment group and control groups were 38.71% and 16.13%, respectively(P<0.05).CONCLUSION: The effect of Gushenyutai plaster plus comprehensive therapy was better than that of the comprehensive therapy alone on male infertility induced by semen non-liquefaction.
